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Alan S. Gamis
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Journal Articles

Rapid Long-Read Epigenomic Diagnosis and Prognosis of Acute Myeloid Leukemia

Free
Francisco Marchi, Ann-Kathrin Schade, Vivek M. Shastri, Xueyuan Cao, Raul C. Ribeiro, Jeffrey E. Rubnitz, Jeffery M Klco, Alan S Gamis, Rhonda E. Ries, Anders Kolb, Richard Aplenc, Todd A. Alonzo, Stanley Pounds, Soheil Meshinchi, Jatinder K. Lamba
Journal: Blood
Blood (2024) 144 (Supplement 1): 103.
https://doi.org/10.1182/blood-2024-207665
Published: 2024
Journal Articles

Treatment Intensification Does Not Improve Outcome for Children with Myeloid Leukemia of Down Syndrome (ML-DS) Who Are MRD-Positive after Induction Therapy: A Report from the Children's Oncology Group

Free
Johann K. Hitzler, Todd A. Alonzo, Robert Gerbing, Jim Wang, Amy Beckman, Betsy Hirsch, Susana C. Raimondi, Karen M Chisholm, Shelton A. Viola, Anupam Verma, Lisa Eidenschink Brodersen, Michael R. Loken, Jeffrey W. Taub, Alan S Gamis, E. Anders Kolb, Todd M Cooper, Jason N. Berman
Journal: Blood
Blood (2024) 144 (Supplement 1): 2949.
https://doi.org/10.1182/blood-2024-202621
Published: 2024
Journal Articles

Gene Expression Profiling in Pediatric AML Patients with Febrile Neutropenia during Induction Therapy

Free
Satyavardhan Rao Nittu, Nam Nguyen, Jim Wang, Todd A. Alonzo, Richard Aplenc, Alan S Gamis, Anders Kolb, Soheil Meshinchi, Jatinder K. Lamba
Journal: Blood
Blood (2024) 144 (Supplement 1): 6119.
https://doi.org/10.1182/blood-2024-210446
Published: 2024
Journal Articles

Proteomic Characterization of Pediatric Acute Lymphoblastic Leukemias Sheds Light on Subtype-Specific Molecular Mechanisms

Free
Irina Pushel, Zachary Clark, Michaella J Rekowski, Lisa A Lansdon, Byunggil Yoo, Keith J August, Alan S Gamis, Erin M. Guest, Michael P Washburn, Midhat S Farooqi
Journal: Blood
Blood (2024) 144 (Supplement 1): 5920.
https://doi.org/10.1182/blood-2024-208937
Published: 2024
Journal Articles

Molecular Characteristics Influencing Relapse Risk in Low-Risk Pediatric Acute Myeloid Leukemia

Free
Lusha Cao, Yang Xu, Tina Glisovic-Aplenc, Han R Fisher, Saamia Farooki, Kelly D. Getz, Todd A. Alonzo, Alan S Gamis, Soheil Meshinchi, Yi Xing, Richard Aplenc
Journal: Blood
Blood (2024) 144 (Supplement 1): 2932.
https://doi.org/10.1182/blood-2024-200851
Published: 2024
Journal Articles

Anti-Leukemic Activity of Luveltamab Tazevibulin (LT, STRO-002), a Novel Folate Receptor-α (FR-α)-Targeting Antibody Drug Conjugate (ADC) in Relapsed/Refractory CBF2AT3::GLIS2 AML

Free
Robin Williams, Lane Miller, Stephanie Massaro, Elizabeth Krieger, Melinda Pauly, Catherine Nelson, Rebecca Johnson, Jennifer J.G. Welch, Deepa Bhojwani, Babak Moghimi, Philip Neff, Terzah M. Horton, Hamayun Imran, Raul C. Ribeiro, Terri L. Guinipero, Matthew A. Kutny, Felipe Bautista, Amy Johnson, Karen Lewing, Alan S Gamis, Julienne Brackett, David McCall, Teena Bhatla, Maria Luisa Sulis, Amy Tellinghuisen, Jill C. Beck, Soheil Meshinchi
Journal: Blood
Blood (2023) 142 (Supplement 1): 4295.
https://doi.org/10.1182/blood-2023-180141
Published: 2023
Journal Articles

The Methylome Atlas of Acute Leukemia Enables Novel Clinical Diagnostic Tool for AML

Free
Francisco Marchi, Marieke Landwehr, Fernando Sckaff, Xueyuan Cao, Raul C. Ribeiro, Jeffrey E. Rubnitz, Alan S Gamis, E. Anders Kolb, Richard Aplenc, Stanley Pounds, Todd A. Alonzo, Soheil Meshinchi, Jatinder K. Lamba
Journal: Blood
Blood (2023) 142 (Supplement 1): 121.
https://doi.org/10.1182/blood-2023-186894
Published: 2023
Journal Articles

Leveraging Custom CRISPR/Cas9 Screens to Identify AraC-Daunorubicin-Etoposide (ADE), Gemtuzumab Ozogamicin (GO), and Bortezomib Response Modulators Association with Clinical Outcomes in Pediatric AML

Free
Nam Nguyen, Phani Krishna Parcha, Abderrahmane Tagmount, Bailey Gregory, Jeffrey E. Rubnitz, Raul C. Ribeiro, Xueyuan Cao, Todd A. Alonzo, Richard Aplenc, Alan S Gamis, Todd Cooper, E. Anders Kolb, Soheil Meshinchi, Stanley Pounds, Christopher Vulpe, Jatinder K. Lamba
Journal: Blood
Blood (2023) 142 (Supplement 1): 1558.
https://doi.org/10.1182/blood-2023-178832
Published: 2023
Journal Articles

Relapse-Enriched Gene Expression Signature of Prognostic Relevance in Pediatric Acute Myeloid Leukemia

Free
Satyavardhan Rao Nittu, Francisco Marchi, Nam Nguyen, Vivek M. Shastri, Xueyuan Cao, Raul C. Ribeiro, Jeffrey E. Rubnitz, Alan S Gamis, E. Anders Kolb, Richard Aplenc, Jeffery Klco, Stanley Pounds, Todd A. Alonzo, Soheil Meshinchi, Jatinder K. Lamba
Journal: Blood
Blood (2023) 142 (Supplement 1): 2926.
https://doi.org/10.1182/blood-2023-189029
Published: 2023
Journal Articles

Single-Cell RNA Sequencing Facilitates Study of Cancer Mechanisms across Pediatric Leukemias

Free
Irina Pushel, Byunggil Yoo, Daniel Louiselle, Margaret Gibson, Alan S Gamis, Keith J. August, Terrie Flatt, Tomi Pastinen, Erin M. Guest, Midhat S Farooqi
Journal: Blood
Blood (2023) 142 (Supplement 1): 1614.
https://doi.org/10.1182/blood-2023-187340
Published: 2023
Journal Articles

A DNA Methylation Signature Predicts Clinical Outcome in Pediatric AML Patients

Free
Francisco Marchi, Marieke Landwehr, Fernando Sckaff, Xueyuan Cao, Raul C. Ribeiro, Jeffrey E. Rubnitz, Alan S Gamis, E. Anders Kolb, Richard Aplenc, Stanley Pounds, Todd A. Alonzo, Soheil Meshinchi, Jatinder K. Lamba
Journal: Blood
Blood (2023) 142 (Supplement 1): 835.
https://doi.org/10.1182/blood-2023-186505
Published: 2023
Journal Articles

ACS10- Cytarabine Pharmacogenomics Score Impacts Survival in Pediatric AML Patients Treated on AAML1031 Trial and Associates with Outcome Differences in Black AML Patients

Free
Richard J Marrero, Vivek M. Shastri, Richard Aplenc, Todd Cooper, Todd A. Alonzo, Alan S Gamis, Jim Wang, Soheil Meshinchi, E. Anders Kolb, Jatinder K. Lamba
Journal: Blood
Blood (2023) 142 (Supplement 1): 4314.
https://doi.org/10.1182/blood-2023-187515
Published: 2023
Journal Articles

Impact of Molecular Risk on Efficacy of Blood and Marrow Transplantation for Pediatric Acute Myeloid Leukemia: A Report from the Children's Oncology Group

Free
Benjamin J Huang, Lauren K. Meyer, Adam Lamble, Jim Wang, Rhonda E Ries, Alan S Gamis, Richard Aplenc, Katherine Tarlock, Todd Cooper, E. Anders Kolb, Todd A. Alonzo, Soheil Meshinchi, Joseph Chewning, William G. Woods, John T. Horan
Journal: Blood
Blood (2023) 142 (Supplement 1): 655.
https://doi.org/10.1182/blood-2023-186955
Published: 2023
Journal Articles

DNMT3A Mutants Are Enriched in NPMc+ AML and Associated with Adverse Outcome in Childhood AML

Free
Rhonda E Ries, Xiaotu Ma, Claudia Tregnago, Todd A. Alonzo, Jim Wang, Tiffany Hylkema, Benjamin J Huang, Alireza Torabi, Jack H Peplinski, Logan K Wallace, Richard Aplenc, Alan S Gamis, Katherine Tarlock, Franco Locatelli, Martina Pigazzi, Soheil Meshinchi
Journal: Blood
Blood (2023) 142 (Supplement 1): 4306.
https://doi.org/10.1182/blood-2023-181060
Published: 2023
Journal Articles

Integrated Methylation and Transcriptional Landscape and Evolution of Pediatric AML

Free
Benjamin J Huang, Hamid Bolouri, Colin Y. Smith, Jim Wang, Rhonda E Ries, Elizabeth Conran, Alan S Gamis, Richard Aplenc, Todd A. Alonzo, Xiaotu Ma, Timothy Junius Triche, Jason E Farrar, Soheil Meshinchi
Journal: Blood
Blood (2023) 142 (Supplement 1): 2956.
https://doi.org/10.1182/blood-2023-187819
Published: 2023
Journal Articles

Pathogenic TP53 mutations Are Associated with a Poor Prognosis in De Novo AML

Free
Adam J. Lamble, Rhonda E. Ries, Alice Dang, Todd A. Alonzo, Karen Chisholm, Pandurang Kolekar, Yanling Liu, Quang Tran, Todd M. Cooper, Richard Aplenc, Alan S. Gamis, Edward A. Kolb, Xiaotu Ma, Soheil Meshinchi
Journal: Blood
Blood (2022) 140 (Supplement 1): 6297–6298.
https://doi.org/10.1182/blood-2022-162832
Published: 2022
Journal Articles

A Robust Long Non-Coding RNA Expression Classifier for Risk Stratification in Pediatric AML

Free
Jason E Farrar, Jenny L. Smith, Megan Othus, Benjamin J. Huang, Yi-Cheng Wang, Rhonda E. Ries, Tiffany A. Hylkema, Era L Pogosova-Agadjanyan, Sneha Challa, Amanda R. Leonti, Timothy I. Shaw, Timothy Junius Triche, Jr., Alan S. Gamis, Richard Aplenc, Anders E. Kolb, Xiaotu Ma, Derek Stirewalt, Todd A. Alonzo, Soheil Meshinchi
Journal: Blood
Blood (2022) 140 (Supplement 1): 9173–9174.
https://doi.org/10.1182/blood-2022-168296
Published: 2022
Journal Articles

Desensitization to Pegaspargase in Children with Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma Is Safe and Does Not Require Intensive Care - a Single Center Experience

Free
Keith J August, Tristan Flatt, Joy M. Fulbright, Alan S. Gamis, Julia A. Hays, Maxine J Hetherington, Karen Lewing, Amanda August, Erin Guest
Journal: Blood
Blood (2022) 140 (Supplement 1): 6037–6038.
https://doi.org/10.1182/blood-2022-167549
Published: 2022
Journal Articles

Distinct Latent Trajectory Phenotypes of Left Ventricular Function Associated with Differential Survival Among Children Treated for Acute Myeloid Leukemia: A Report from the Children's Oncology Group

Free
Kelly D. Getz, Robert B. Gerbing, Todd A. Alonzo, Yimei Li, Kasey J Leger, Jessica A. Pollard, Dava Szalda, Lillian Sung, Todd M. Cooper, Edward A. Kolb, Alan S. Gamis, Bonnie Ky, Richard Aplenc
Journal: Blood
Blood (2022) 140 (Supplement 1): 1014–1015.
https://doi.org/10.1182/blood-2022-170218
Published: 2022
Journal Articles

Clinical and Functional Implications of MYC Variants As a New Class of Pathogenic Variants in AML

Free
Danielle C. Kirkey, Xiaoying Wu, Rhonda E. Ries, Tiffany A. Hylkema, Yanling Liu, Pandurang Kolekar, Quang Tran, Alan S. Gamis, Richard Aplenc, Anders E. Kolb, Todd A. Alonzo, Katherine Tarlock, Robert Eisenman, Soheil Meshinchi
Journal: Blood
Blood (2022) 140 (Supplement 1): 3395–3396.
https://doi.org/10.1182/blood-2022-168469
Published: 2022