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Adele Capucci
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Journal Articles

REL-Protocol PhilosoPhi34: An Open Label, Single Arm, Phase II Study of Nilotinib 300 Mg BID in Newly Diagnosed Chronic Phase Chronic Myeloid Leukaemia Patients, to Study the Disappearance of CD34+/Lin-Ph+ Cells from Bone Marrow during Treatment. Preliminary Data

Ester Pungolino, MD, Giuseppe Rossi, MD, Maria Angela Mura, Alessandra Perego, MD, Ester Maria Orlandi, MD, Mauro Turrini, MD, Lorenza Borin, MD, Maria Adele Capucci, MD, Alessandra Iurlo, MD PhD, Alessandra Trojani, PhD, Mariella D'Adda, MD, Francesco Spina, MD, Gabriella De Canal, Maria Luisa Pioltelli, Maria Luisa Latargia, MD, Sergio Pauli, MD, Chiara Elena, MD, Stefania Brusorio, Francesco Lanza, MD, Simona Malato, MD, Michela Anghilieri, MD, Maria C Carraro, MD, Enrica Morra, MD, Roberto Cairoli, MD
Journal: Blood
Blood (2015) 126 (23): 1597.
https://doi.org/10.1182/blood.V126.23.1597.1597
Published: 2015
Journal Articles

Gene Expression Profiling of CD34+/Lin- Cells of Patients with Chronic Myeloid Leukemia at Diagnosis and after 12 Months of Nilotinib

Alessandra Trojani, Milena Lodola, Barbara Di Camillo, Giuseppe Rossi, MD, Adele Capucci, Alessandra Perego, Enrico Maria Pogliani, MD, Ester Orlandi, MD, Alessandra Iurlo, MD PhD, Simona Malato, Paolo Corradini, MD, Roberto Cairoli, Marco Bregni, Salvatore Artale, Enrica Morra, Ester Pungolino, MD
Journal: Blood
Blood (2014) 124 (21): 5177.
https://doi.org/10.1182/blood.V124.21.5177.5177
Published: 2014
Journal Articles

Microarray of Bone Marrow CD34+/Lin- Cells from Patients with Chronic Myeloid Leukemia (CML)

Alessandra Trojani, Milena Lodola, Barbara Di Camillo, Giuseppe Rossi, MD, Adele Capucci, Alessandra Perego, Enrico Maria Pogliani, MD, Ester Orlandi, MD, Alessandra Iurlo, MD PhD, Simona Malato, Paolo Corradini, MD, Roberto Cairoli, Marco Bregni, Sergio Pauli, Enrica Morra, Ester Pungolino, MD
Journal: Blood
Blood (2014) 124 (21): 5178.
https://doi.org/10.1182/blood.V124.21.5178.5178
Published: 2014
Journal Articles

Frontline Treatment With Imatinib Mesylate in Chronic Myeloid Leukemia Patients in Early Chronic Phase: a Very Long-Term Analysis by the GIMEMA CML Working Party

Fausto Castagnetti, Gabriele Gugliotta, Massimo Breccia, Giorgina Specchia, Tamara Intermesoli, Adele Capucci, Bruno Martino, MD, Mario Tiribelli, MD, Gianni Binotto, MD, Elisabetta Abruzzese, MD, PhD, Fabio Stagno, MD, Pietro Leoni, MD, Dario Ferrero, MD, Filippo Gherlinzoni, MD, Francesca Palandri, Claudia Venturi, Maria Teresa Bochicchio, Simona Soverini, Giuliana Alimena, MD, Giovanni Martinelli, Fabrizio Pane, MD, Giuseppe Saglio, MD, Michele Cavo, MD, Michele Baccarani, MD, Gianantonio Rosti
Journal: Blood
Blood (2013) 122 (21): 258.
https://doi.org/10.1182/blood.V122.21.258.258
Published: 2013
Journal Articles

Cytogenetic and Molecular Responses At 3 Months Are Associated with A Better Outcome in Early Chronic Phase (ECP) Chronic Myeloid Leukemia (CML) Patients Treated with Nilotinib.

Gabriele Gugliotta, Fausto Castagnetti, Francesca Palandri, Massimo Breccia, Luciano Levato, Fabio Stagno, Giovanna Rege-Cambrin, Alfonso Zaccaria, Giorgina Specchia, Emilio Usala, Antonella Gozzini, Bruno Martino, Adele Capucci, Pellegrino Musto, Mario Tiribelli, Elisabetta Abruzzese, Simona Soverini, Maria Teresa Bochicchio, Nicoletta Testoni, Giuseppe Saglio, Giovanni Martinelli, Fabrizio Pane, Giuliana Alimena, Michele Baccarani, MD, Gianantonio Rosti, prof
Journal: Blood
Blood (2012) 120 (21): 2797.
https://doi.org/10.1182/blood.V120.21.2797.2797
Published: 2012
Journal Articles

Five-Year Results of Nilotinib 400 Mg BID in Early Chronic Phase Chronic Myeloid Leukemia (CML): High Rate of Deep Molecular Response - Update of the Gimema CML WP Trial CML0307

Gianantonio Rosti, prof, Gabriele Gugliotta, Fausto Castagnetti, Massimo Breccia, Luciano Levato, Giovanna Rege-Cambrin, Adele Capucci, Mario Tiribelli, Alfonso Zaccaria, Monica Bocchia, Fabio Stagno, Francesco Cavazzini, Giorgina Specchia, Bruno Martino, Michele Cedrone, Tamara Intermesoli, Francesca Palandri, Simona Soverini, Maria Teresa Bochicchio, Nicoletta Testoni, Giuliana Alimena, Fabrizio Pane, Giuseppe Saglio, Giovanni Martinelli, Michele Baccarani, MD
Journal: Blood
Blood (2012) 120 (21): 3784.
https://doi.org/10.1182/blood.V120.21.3784.3784
Published: 2012
Journal Articles

Additional chromosomal abnormalities in Philadelphia-positive clone: adverse prognostic influence on frontline imatinib therapy: a GIMEMA Working Party on CML analysis

Clinical Trials & Observations
Simona Luatti, Fausto Castagnetti, Giulia Marzocchi, Carmen Baldazzi, Gabriele Gugliotta, Ilaria Iacobucci, Giorgina Specchia, Lucia Zanatta, Giovanna Rege-Cambrin, Marco Mancini, Elisabetta Abruzzese, Alfonso Zaccaria, Maria Grazia Grimoldi, Alessandro Gozzetti, Gaia Ameli, Maria Adele Capucci, Giandomenico Palka, Paolo Bernasconi, Francesca Palandri, Fabrizio Pane, Giuseppe Saglio, Giovanni Martinelli, Gianantonio Rosti, Michele Baccarani, Nicoletta Testoni
Journal: Blood
Blood (2012) 120 (4): 761–767.
https://doi.org/10.1182/blood-2011-10-384651
Published: 2012
Journal Articles

Early CP CML, Nilotinib 400 mg Twice Daily Frontline: Beyond 3 Years, Results Remain Excellent and Stable (A GIMEMA CML Working Party Trial)

Gabriele Gugliotta, Fausto Castagnetti, Massimo Breccia, Luciano Levato, Adele Capucci, Mario Tiribelli, Alfonso Zaccaria, Monica Bocchia, Antonio Cuneo, Fabio Stagno, Giorgina Specchia, Maurizio Musso, Bruno Martino, Michele Cedrone, Tamara Intermesoli, Francesca Palandri, Simona Soverini, Carmen Baldazzi, Sandra Durante, Nicoletta Testoni, Giuliana Alimena, Fabrizio Pane, Giuseppe Saglio, MD, Michele Baccarani, MD, Giovanni Martinelli, Gianantonio Rosti, MD
Journal: Blood
Blood (2011) 118 (21): 2756.
https://doi.org/10.1182/blood.V118.21.2756.2756
Published: 2011
Journal Articles

Alternating Nilotinib 400 mg twice daily and Imatinib 400 mg once daily as Frontline Treatment of Ph+ Chronic Myeloid Leukemia. A Phase 2 Multicentric Study of the GIMEMA CML Working Party

Fausto Castagnetti, Gianantonio Rosti, MD, Massimo Breccia, Antonella Gozzini, MD, Fabio Stagno, MD, PhD, Giovanna Rege Cambrin, Ivana Pierri, Luigia Luciano, MD, Giorgina Specchia, Elisabetta Abruzzese, Bruno Martino, Adele Capucci, Monica Bocchia, Francesco Cavazzini, Mario Tiribelli, Gabriele Gugliotta, Francesca Palandri, Sandra Durante, Simona Soverini, Nicoletta Testoni, Fabrizio Pane, Giuseppe Saglio, MD, Giuliana Alimena, Giovanni Martinelli, MD, Michele Baccarani, MD
Journal: Blood
Blood (2011) 118 (21): 453.
https://doi.org/10.1182/blood.V118.21.453.453
Published: 2011
Journal Articles

Frontline imatinib treatment of chronic myeloid leukemia: no impact of age on outcome, a survey by the GIMEMA CML Working Party

CME
Gabriele Gugliotta, Fausto Castagnetti, Francesca Palandri, Massimo Breccia, Tamara Intermesoli, Adele Capucci, Bruno Martino, Patrizia Pregno, Serena Rupoli, Dario Ferrero, Filippo Gherlinzoni, Enrico Montefusco, Monica Bocchia, Mario Tiribelli, Ivana Pierri, Federica Grifoni, Giulia Marzocchi, Marilina Amabile, Nicoletta Testoni, Giovanni Martinelli, Giuliana Alimena, Fabrizio Pane, Giuseppe Saglio, Michele Baccarani, Gianantonio Rosti, on behalf of the Gruppo Italiano Malattie Ematologiche dell'Adulto CML Working Party
Journal: Blood
Blood (2011) 117 (21): 5591–5599.
https://doi.org/10.1182/blood-2010-12-324228
Published: 2011
Journal Articles

First Line Treatment with Nilotinib 800 Mg Daily Results In Unprecedentedly High Rate of Rapid, “Deep” and Stable Molecular Responses as Assessed by a High Sensitive Nanofluidic Array for the Detection of Rare Copies of BCR-ABL1 Transcript: Results of a Phase 2 Trial of the GIMEMA CML Working Party

Giovanni Martinelli, Angela Poerio, Marilina Amabile, Ilaria Iacobucci, Simona Soverini, Fausto Castagnetti, Francesca Palandri, Gabriele Gugliotta, Adele Capucci, Mario Tiribelli, Fabio Stagno, MD, Alfonso Zaccaria, Tamara Intermesoli, Bruno Martino, Monica Bocchia, Michele Cedrone, Nicoletta Testoni, Massimo Breccia, MD, Giuliana Alimena, MD, Luciano Levato, Cristina Papayannidis, Annalisa Lonetti, Carolina Terragna, Domenico Russo, Fabrizio Pane, MD, Giuseppe Saglio, MD, PhD, Gianantonio Rosti, Michele Baccarani, MD
Journal: Blood
Blood (2010) 116 (21): 2720.
https://doi.org/10.1182/blood.V116.21.2720.2720
Published: 2010
Journal Articles

Excellent Outcomes at 3 Years with Nilotinib 800 Mg Daily In Early Chronic Phase, Ph+ Chronic Myeloid Leukemia (CML): Results of a Phase 2 GIMEMA CML WP Clinical Trial

Gianantonio Rosti, Fausto Castagnetti, Gabriele Gugliotta, Massimo Breccia, Luciano Levato, Adele Capucci, Mario Tiribelli, Alfonso Zaccaria, Monica Bocchia, Antonio Cuneo, Fabio Stagno, Giorgina Specchia, Ferdinando Porretto, Bruno Martino, Michele Cedrone, Tamara Intermesoli, Francesca Palandri, Marilina Amabile, Simona Soverini, Nicoletta Testoni, Giuliana Alimena, Fabrizio Pane, Giuseppe Saglio, Giovanni Martinelli, Michele Baccarani
Journal: Blood
Blood (2010) 116 (21): 359.
https://doi.org/10.1182/blood.V116.21.359.359
Published: 2010
Journal Articles

BCR-ABL Fusion Transcript Do Not Significantly Influence the Outcome of Chronic Myeloid Leukemia Patients In Early Chronic Phase Treated with Imatinib Mesylate: a GIMEMA CML WP Analysis.

Fausto Castagnetti, Gabriele Gugliotta, Francesca Palandri, Massimo Breccia, Giorgina Specchia, Elisabetta Abruzzese, Tamara Intermesoli, Adele Capucci, Bruno Martino, Fabio Stagno, Patrizia Pregno, Marilina Amabile, Simona Soverini, Nicoletta Testoni, Giuliana Alimena, Giovanni Martinelli, Fabrizio Pane, Giuseppe Saglio, Michele Baccarani, Gianantonio Rosti
Journal: Blood
Blood (2010) 116 (21): 1230.
https://doi.org/10.1182/blood.V116.21.1230.1230
Published: 2010
Journal Articles

Nilotinib for the frontline treatment of Ph + chronic myeloid leukemia

Clinical Trials & Observations
Gianantonio Rosti, Francesca Palandri, Fausto Castagnetti, Massimo Breccia, Luciano Levato, Gabriele Gugliotta, Adele Capucci, Michele Cedrone, Carmen Fava, Tamara Intermesoli, Giovanna Rege Cambrin, Fabio Stagno, Mario Tiribelli, Marilina Amabile, Simona Luatti, Angela Poerio, Simona Soverini, Nicoletta Testoni, Giovanni Martinelli, Giuliana Alimena, Fabrizio Pane, Giuseppe Saglio, Michele Baccarani, for the GIMEMA CML Working Party
Journal: Blood
Blood (2009) 114 (24): 4933–4938.
https://doi.org/10.1182/blood-2009-07-232595
Published: 2009
Journal Articles

Chronic Myeloid Leukemia (CML) Patients with “Suboptimal” Response to Imatinib (IM) According to European LeukemiaNet Criteria Have a Poorer Outcome with Respect to “Optimal” Responders: A GIMEMA CML WORKING PARTY Analysis.

Fausto Castagnetti, Gabriele Gugliotta, Francesca Palandri, Massimo Breccia, Marilina Amabile, Ilaria Iacobucci, Nicoletta Testoni, Giulia Marzocchi, Simona Luatti, Giorgina Specchia, Tamara Intermesoli, Elisabetta Abruzzese, Adele Capucci, Luciano Levato, Franca Radaelli, Bruno Martino, Patrizia Pregno, Enrico Montefusco, Livio Trentin, Giuliana Alimena, Giovanni Martinelli, Fabrizio Pane, Giuseppe Saglio, MD, Michele Baccarani, Gianantonio Rosti
Journal: Blood
Blood (2009) 114 (22): 2196.
https://doi.org/10.1182/blood.V114.22.2196.2196
Published: 2009
Journal Articles

Nilotinib 800 Mg Daily as Frontline Therapy of Ph + Chronic Myeloid Leukemia: Dose Delivered and Safety Profile for the GIMEMA CML Working Party.

Gianantonio Rosti, Fausto Castagnetti, Francesca Palandri, Massimo Breccia, Luciano Levato, Gabriele Gugliotta, Adele Capucci, Michele Cedrone, Carmen Fava, MD, Tamara Intermesoli, MD, Giovanna Rege Cambrin, Fabio Stagno, Mario Tiribelli, Marilina Amabile, Simona Luatti, Angela Poerio, Simona Soverini, PhD, Nicoletta Testoni, Giuliana Alimena, Fabrizio Pane, MD, Giuseppe Saglio, MD, Michele Baccarani, Giovanni Martinelli, MD
Journal: Blood
Blood (2009) 114 (22): 2205.
https://doi.org/10.1182/blood.V114.22.2205.2205
Published: 2009
Journal Articles

Epidemiology, Risk Factors and Outcome of 282 Bloodstream Infections among Hematological Patients: Results of a 50 Months Prospective Surveillance Study

Chiara Cattaneo, Francesca Bracchi, Salvatore Casari, Erika Borlenghi, Maria Adele Capucci, Anna Maria Pelizzari, Liana Signorini, Massimiliano De Vecchi, Monica Drera, Alessandro Re, Giampiero Carosi, Giuseppe Rossi
Journal: Blood
Blood (2008) 112 (11): 4835.
https://doi.org/10.1182/blood.V112.11.4835.4835
Published: 2008
Journal Articles

High and Early Rates of Cytogenetic and Molecular Response with Nilotinib 800 Mg Daily as First Line Treatment of Ph-Positive Chronic Myeloid Leukemia in Chronic Phase: Results of a Phase 2 Trial of the GIMEMA CML Working Party

Gianantonio Rosti, Fausto Castagnetti, Angela Poerio, Massimo Breccia, Luciano Levato, Adele Capucci, Mario Tiribelli, Fabio Stagno, Alfonso Zaccaria, Tamara Intermesoli, Bruno Martino, Monica Bocchia, Michele Cedrone, Francesco Bartucci, Francesca Palandri, Gabriele Gugliotta, Nicoletta Testoni, Giuliana Alimena, Giovanni Martinelli, Fabrizio Pane, MD, Giuseppe Saglio, Michele Baccarani
Journal: Blood
Blood (2008) 112 (11): 181.
https://doi.org/10.1182/blood.V112.11.181.181
Published: 2008
Journal Articles

A 3-Year Prospective Surveillance Study of Microbiological Isolates among Hematologic Inpatients Shows a High Frequency of Both Community-Acquired and Nosocomial Methicillin-Resistant (MR) and Fluoroquinolone-Resistant (FqR) Strains and the Recent Increase of Enterococci, Viridans Streptococci and Pseudomonaceae with Frequent Antibiotic Multiresistance.

Chiara Cattaneo, MD, Salvatore Casari, MD, Erika Borlenghi, MD, Maria Adele Capucci, MD, Moira Micheletti, MD, Alessandro Re, MD, Giampiero Carosi, MD, Giuseppe Rossi, MD
Journal: Blood
Blood (2007) 110 (11): 2286.
https://doi.org/10.1182/blood.V110.11.2286.2286
Published: 2007
Journal Articles

Treatment of Philadelphia Positive Chronic Myeloid Leukemia with Imatinib: Introducing the Concept of Confirmed Molecular Response.

Francesca Palandri, MD, Gianantonio Rosti, MD, Ilaria Iacobucci, MD, Nicoletta Testoni, MD, Fausto Castagnetti, MD, Massimo Breccia, MD, Elisabetta Abruzzese, MD, Bruno Martino, MD, Daniela Cilloni, MD, Fabrizio Pane, MD, Marco Gobbi, MD, Tamara Intermesoli, MD, Fabio Stagno, MD, Adele Capucci, MD, Giovanni Martinelli, MD, Michele Baccarani, MD
Journal: Blood
Blood (2007) 110 (11): 1933.
https://doi.org/10.1182/blood.V110.11.1933.1933
Published: 2007