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Volume 99, Issue 8

April 15 2002

In this Issue

INSIDE BLOOD
PLENARY PAPERS
REVIEW ARTICLES
CHEMOKINES
CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS
HEMATOPOIESIS
HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY
IMMUNOBIOLOGY
NEOPLASIA
PHAGOCYTES
RED CELLS
TRANSFUSION MEDICINE
TRANSPLANTATION
BRIEF REPORTS
CORRESPONDENCE

INSIDE BLOOD

Acute promyelocytic leukemia: STATs, HATs, and HDACs

Steven J. Collins

View Articletitled, Acute promyelocytic leukemia: STATs, HATs, and HDACs

Reconstitution of active NADPH oxidase in nonhematopoietic cells: a milestone in the study of a complex system

Tomas Ganz

View Articletitled, Reconstitution of active NADPH oxidase in nonhematopoietic cells: a milestone in the study of a complex system

Gene therapy for hemophilia B in dogs: finally prevention of bleeding, but concerns about inhibitors remain

Katherine Ponder

View Articletitled, Gene therapy for hemophilia B in dogs: finally prevention of bleeding, but concerns about inhibitors remain

PLENARY PAPERS

Interactions of STAT5b-RARα, a novel acute promyelocytic leukemia fusion protein, with retinoic acid receptor and STAT3 signaling pathways

Shuo Dong,David J. Tweardy

View Articletitled, Interactions of STAT5b-RARα, a novel acute promyelocytic leukemia fusion protein, with retinoic acid receptor and STAT3 signaling pathways

The Stat5-RARα fusion protein represses transcription and differentiation through interaction with a corepressor complex

Alexander B. Maurer,Christian Wichmann,Alexandra Gross,Hana Kunkel,Thorsten Heinzel,Martin Ruthardt,Bernd Groner,Manuel Grez

View Articletitled, The Stat5-RARα fusion protein represses transcription and differentiation through interaction with a corepressor complex

Creation of a genetic system for analysis of the phagocyte respiratory burst: high-level reconstitution of the NADPH oxidase in a nonhematopoietic system

Marianne O. Price,Linda C. McPhail,J. David Lambeth,Chang-Hoon Han,Ulla G. Knaus,Mary C. Dinauer

View Articletitled, Creation of a genetic system for analysis of the phagocyte respiratory burst: high-level reconstitution of the NADPH oxidase in a nonhematopoietic system

IRTAs: a new family of immunoglobulinlike receptors differentially expressed in B cells

Ira Miller,Georgia Hatzivassiliou,Giorgio Cattoretti,Cathy Mendelsohn,Riccardo Dalla-Favera

View Articletitled, IRTAs: a new family of immunoglobulinlike receptors differentially expressed in B cells

Sustained phenotypic correction of hemophilia B dogs with a factor IX null mutation by liver-directed gene therapy

Jane D. Mount,Roland W. Herzog,D. Michael Tillson,Susan A. Goodman,Nancy Robinson,Mark L. McCleland,Dwight Bellinger,Timothy C. Nichols,Valder R. Arruda,Clinton D. Lothrop, Jr,Katherine A. High

View Articletitled, Sustained phenotypic correction of hemophilia B dogs with a factor IX null mutation by liver-directed gene therapy

Plasmodium yoelii uses the murine Duffy antigen receptor for chemokines as a receptor for normocyte invasion and an alternative receptor for reticulocyte invasion

Christine J. Swardson-Olver,Tracey C. Dawson,Robert C. Burnett,Stephen C. Peiper,Nobuyo Maeda,Anne C. Avery

View Articletitled, Plasmodium yoelii uses the murine Duffy antigen receptor for chemokines as a receptor for normocyte invasion and an alternative receptor for reticulocyte invasion

Dose-adjusted EPOCH chemotherapy for untreated large B-cell lymphomas: a pharmacodynamic approach with high efficacy

Wyndham H. Wilson,Michael L. Grossbard,Stefania Pittaluga,Diane Cole,Deborah Pearson,Nicole Drbohlav,Seth M. Steinberg,Richard F. Little,John Janik,Martin Gutierrez,Mark Raffeld,Louis Staudt,Bruce D. Cheson,Dan L. Longo,Nancy Harris,Elaine S. Jaffe,Bruce A. Chabner,Robert Wittes,Frank Balis

View Articletitled, Dose-adjusted EPOCH chemotherapy for untreated large B-cell lymphomas: a pharmacodynamic approach with high efficacy

REVIEW ARTICLES

Autoimmunity in human primary immunodeficiency diseases

Peter D. Arkwright,Mario Abinun,Andrew J. Cant

View Articletitled, Autoimmunity in human primary immunodeficiency diseases

CHEMOKINES

Regulation of endothelial cell branching morphogenesis by endogenous chemokine stromal-derived factor-1

Ombretta Salvucci,Lei Yao,Sabrina Villalba,Agatha Sajewicz,Stefania Pittaluga,Giovanna Tosato

View Articletitled, Regulation of endothelial cell branching morphogenesis by endogenous chemokine stromal-derived factor-1

CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS

A humanized non–FcR-binding anti-CD3 antibody, visilizumab, for treatment of steroid-refractory acute graft-versus-host disease
Clinical Trials & Observations

Paul A. Carpenter,Frederick R. Appelbaum,Lawrence Corey,H. Joachim Deeg,Kris Doney,Theodore Gooley,James Krueger,Paul Martin,Sandra Pavlovic,Jean Sanders,John Slattery,Daniel Levitt,Rainer Storb,Ann Woolfrey,Claudio Anasetti

View Articletitled, A humanized non–FcR-binding anti-CD3 antibody, visilizumab, for treatment of steroid-refractory acute graft-versus-host disease

A prospective study of venous thromboembolism in relation to factor V Leiden and related factors
Clinical Trials & Observations

Aaron R. Folsom,Mary Cushman,Michael Y. Tsai,Nena Aleksic,Susan R. Heckbert,Lori L. Boland,Albert W. Tsai,N. David Yanez,Wayne D. Rosamond

View Articletitled, A prospective study of venous thromboembolism in relation to factor V Leiden and related factors

Association of CD34 cell dose with hematopoietic recovery, infections, and other outcomes after HLA-identical sibling bone marrow transplantation
Clinical Trials & Observations

Henrique Bittencourt,Vanderson Rocha,Sylvie Chevret,Gérard Socié,Hélène Espérou,Agnès Devergie,Liliane Dal Cortivo,Jean-Pierre Marolleau,Federico Garnier,Patricia Ribaud,Eliane Gluckman

View Articletitled, Association of CD34 cell dose with hematopoietic recovery, infections, and other outcomes after HLA-identical sibling bone marrow transplantation

Comparison of Escherichia coli–asparaginase withErwinia-asparaginase in the treatment of childhood lymphoid malignancies: results of a randomized European Organisation for Research and Treatment of Cancer—Children's Leukemia Group phase 3 trial
Clinical Trials & Observations

Michel Duval,Stefan Suciu,Alina Ferster,Xavier Rialland,Brigitte Nelken,Patrick Lutz,Yves Benoit,Alain Robert,Anne-Marie Manel,Etienne Vilmer,Jacques Otten,Noël Philippe,for the European Organisation for Research and Treatment of Cancer—Children's Leukemia Group

View Articletitled, Comparison of Escherichia coli–asparaginase withErwinia-asparaginase in the treatment of childhood lymphoid malignancies: results of a randomized European Organisation for Research and Treatment of Cancer—Children's Leukemia Group phase 3 trial

HEMATOPOIESIS

Receptor tyrosine kinase, EphB4 (HTK), accelerates differentiation of select human hematopoietic cells

Zhengyu Wang,Nobuyuki Miura,Andres Bonelli,Pamela Mole,Nadia Carlesso,Douglas P. Olson,David T. Scadden

View Articletitled, Receptor tyrosine kinase, EphB4 (HTK), accelerates differentiation of select human hematopoietic cells

Long-term support of hematopoiesis by a single stem cell clone in patients with paroxysmal nocturnal hemoglobinuria
Clinical Trials & Observations

Jun-ichi Nishimura,Toshiyuki Hirota,Yuzuru Kanakura,Takashi Machii,Takashi Kageyama,Shoichi Doi,Hiroshi Wada,Toru Masaoka,Yoshio Kanayama,Hiroshi Fujii,Nobumasa Inoue,Maki Kuwayama,Norimitsu Inoue,Kazuhito Ohishi,Taroh Kinoshita

View Articletitled, Long-term support of hematopoiesis by a single stem cell clone in patients with paroxysmal nocturnal hemoglobinuria

Intrathymic and extrathymic development of human plasmacytoid dendritic cell precursors in vivo

Kees Weijer,Christel H. Uittenbogaart,Arie Voordouw,Franka Couwenberg,Jurgen Seppen,Bianca Blom,Florry A. Vyth-Dreese,Hergen Spits

View Articletitled, Intrathymic and extrathymic development of human plasmacytoid dendritic cell precursors in vivo

Extensive in vivo self-renewal, long-term reconstitution capacity, and hematopoietic multipotency of Pax5-deficient precursor B-cell clones

Christoph Schaniel,Marie Gottar,Eddy Roosnek,Fritz Melchers,Antonius G. Rolink

View Articletitled, Extensive in vivo self-renewal, long-term reconstitution capacity, and hematopoietic multipotency of Pax5-deficient precursor B-cell clones

Long-term repopulating ability of telomerase-deficient murine hematopoietic stem cells

Enrique Samper,Piedad Fernández,Raúl Eguı́a,Luis Martı́n-Rivera,Antonio Bernad,Marı́a A. Blasco,Miguel Aracil

View Articletitled, Long-term repopulating ability of telomerase-deficient murine hematopoietic stem cells

CCAAT/enhancer-binding proteins are required for granulopoiesis independent of their induction of the granulocyte colony-stimulating factor receptor

Qian-fei Wang,Alan D. Friedman

View Articletitled, CCAAT/enhancer-binding proteins are required for granulopoiesis independent of their induction of the granulocyte colony-stimulating factor receptor

Hematopoietic cells expressing the peripheral cannabinoid receptor migrate in response to the endocannabinoid 2-arachidonoylglycerol

Meritxell Alberich Jordà,Sandra E. Verbakel,Peter J. M. Valk,Yolanda V. Vankan-Berkhoudt,Mauro Maccarrone,Allessandro Finazzi-Agrò,Bob Löwenberg,Ruud Delwel

View Articletitled, Hematopoietic cells expressing the peripheral cannabinoid receptor migrate in response to the endocannabinoid 2-arachidonoylglycerol

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

Coronary no-reflow is caused by shedding of active tissue factor from dissected atherosclerotic plaque

Diana Bonderman,Alexander Teml,Johannes Jakowitsch,Christopher Adlbrecht,Mariann Gyöngyösi,Wolfgang Sperker,Harald Lass,Wilhelm Mosgoeller,Dietmar H. Glogar,Peter Probst,Gerald Maurer,Yale Nemerson,Irene M. Lang

View Articletitled, Coronary no-reflow is caused by shedding of active tissue factor from dissected atherosclerotic plaque

Differential catalytic properties and vascular topography of murine nucleoside triphosphate diphosphohydrolase 1 (NTPDase1) and NTPDase2 have implications for thromboregulation

Jean Sévigny,Christian Sundberg,Norbert Braun,Olaf Guckelberger,Eva Csizmadia,Imrana Qawi,Masato Imai,Herbert Zimmermann,Simon C. Robson

View Articletitled, Differential catalytic properties and vascular topography of murine nucleoside triphosphate diphosphohydrolase 1 (NTPDase1) and NTPDase2 have implications for thromboregulation

Plasminogen activator inhibitor type 2: a regulator of monocyte proliferation and differentiation

Hong Yu,Fabienne Maurer,Robert L. Medcalf

View Articletitled, Plasminogen activator inhibitor type 2: a regulator of monocyte proliferation and differentiation

Agonist-induced aggregation of Chinese hamster ovary cells coexpressing the human receptors for fibrinogen (integrin αIIbβ3) and the platelet-activating factor: dissociation between adhesion and aggregation

Susana Larrucea,Consuelo González-Manchón,Nora Butta,Elena G. Arias-Salgado,Linnan Shen,Matilde S. Ayuso,Roberto Parrilla

View Articletitled, Agonist-induced aggregation of Chinese hamster ovary cells coexpressing the human receptors for fibrinogen (integrin αIIbβ3) and the platelet-activating factor: dissociation between adhesion and aggregation

Two classes of germline genes both derived from the V_H1 family direct the formation of human antibodies that recognize distinct antigenic sites in the C2 domain of factor VIII

Edward N. van den Brink,Wendy S. Bril,Ellen A. M. Turenhout,Marleen Zuurveld,Niels Bovenschen,Marjolein Peters,Thynn Thynn Yee,Koen Mertens,Deborah A. Lewis,Thomas L. Ortel,Pete Lollar,Dorothea Scandella,Jan Voorberg

View Articletitled, Two classes of germline genes both derived from the VH1 family direct the formation of human antibodies that recognize distinct antigenic sites in the C2 domain of factor VIII

Plasmin activity is required for myogenesis in vitro and skeletal muscle regeneration in vivo

Mònica Suelves,Roser López-Alemany,Frederic Lluı́s,Gloria Aniorte,Erika Serrano,Maribel Parra,Peter Carmeliet,Pura Muñoz-Cánoves

View Articletitled, Plasmin activity is required for myogenesis in vitro and skeletal muscle regeneration in vivo

IMMUNOBIOLOGY

Flt3 ligand as a vaccine adjuvant in association with HER-2/neu peptide-based vaccines in patients with HER-2/neu–overexpressing cancers
Clinical Trials & Observations

Mary L. Disis,Kristine Rinn,Keith L. Knutson,Donna Davis,Dania Caron,Corazon dela Rosa,Kathy Schiffman

View Articletitled, Flt3 ligand as a vaccine adjuvant in association with HER-2/neu peptide-based vaccines in patients with HER-2/neu–overexpressing cancers

Effects of exogenous interleukin-7 on human thymus function

Yukari Okamoto,Daniel C. Douek,Richard D. McFarland,Richard A. Koup

View Articletitled, Effects of exogenous interleukin-7 on human thymus function

Disrupted homeostasis of Langerhans cells and interdigitating dendritic cells in monkeys with AIDS

Michael I. Zimmer,Adriana T. Larregina,Cielo M. Castillo,Saverio Capuano, III,Louis D. Falo, Jr,Michael Murphey-Corb,Todd A. Reinhart,Simon M. Barratt-Boyes

View Articletitled, Disrupted homeostasis of Langerhans cells and interdigitating dendritic cells in monkeys with AIDS

Increased dendritic cell number and function following continuous in vivo infusion of granulocyte macrophage–colony-stimulating factor and interleukin-4

Saroj K. Basak,Airi Harui,Marina Stolina,Sherven Sharma,Kohnosuke Mitani,Steven M. Dubinett,Michael D. Roth

View Articletitled, Increased dendritic cell number and function following continuous in vivo infusion of granulocyte macrophage–colony-stimulating factor and interleukin-4

B7-CTLA4 interaction promotes cognate destruction of tumor cells by cytotoxic T lymphocytes in vivo

Xue-Feng Bai,Jinqing Liu,Kenneth F. May, Jr,Yong Guo,Pan Zheng,Yang Liu

View Articletitled, B7-CTLA4 interaction promotes cognate destruction of tumor cells by cytotoxic T lymphocytes in vivo

Human mast cell progenitors use α4-integrin, VCAM-1, and PSGL-1 E-selectin for adhesive interactions with human vascular endothelium under flow conditions

Joshua A. Boyce,Elizabeth A. Mellor,Brandy Perkins,Yaw-Chyn Lim,Francis W. Luscinskas

View Articletitled, Human mast cell progenitors use α4-integrin, VCAM-1, and PSGL-1 E-selectin for adhesive interactions with human vascular endothelium under flow conditions

Spontaneous generation and survival of blood dendritic cells in mononuclear cell culture without exogenous cytokines

Christopher S. K. Ho,David Munster,Christopher M. Pyke,Derek N. J. Hart,J. Alejandro López

View Articletitled, Spontaneous generation and survival of blood dendritic cells in mononuclear cell culture without exogenous cytokines

IgG plasma cells display a unique spectrum of leukocyte adhesion and homing molecules

Gregory H. Underhill,Heather A. Minges-Wols,Jamie L. Fornek,Pamela L. Witte,Geoffrey S. Kansas

View Articletitled, IgG plasma cells display a unique spectrum of leukocyte adhesion and homing molecules

Human cytomegalovirus inhibits maturation and impairs function of monocyte-derived dendritic cells

Magdalena Moutaftsi,Anja M. Mehl,Leszek K. Borysiewicz,Zsuzsanna Tabi

View Articletitled, Human cytomegalovirus inhibits maturation and impairs function of monocyte-derived dendritic cells

Level of galactosylation determines cryoglobulin activity of murine IgG3 monoclonal rheumatoid factor

Aki Kuroki,Yasuhiro Kuroda,Shuichi Kikuchi,Frédéric Lajaunias,Thierry Fulpius,Yves Pastore,Liliane Fossati-Jimack,Luc Reininger,Toho Toda,Munehiro Nakata,Naoya Kojima,Tsuguo Mizuochi,Shozo Izui

View Articletitled, Level of galactosylation determines cryoglobulin activity of murine IgG3 monoclonal rheumatoid factor

The growth of cutaneous T-cell lymphoma is stimulated by immature dendritic cells

Carole L. Berger,Douglas Hanlon,Daniel Kanada,Madhav Dhodapkar,Vivian Lombillo,Nianci Wang,Inger Christensen,Gregory Howe,Jill Crouch,Paul El-Fishawy,Richard Edelson

View Articletitled, The growth of cutaneous T-cell lymphoma is stimulated by immature dendritic cells

Supplemental data

CD95 engagement induces disseminated endothelial cell apoptosis in vivo: immunopathologic implications

Anne Janin,Christophe Deschaumes,Marjan Daneshpouy,Jérôme Estaquier,Juliette Micic-Polianski,Premavathy Rajagopalan-Levasseur,Khadija Akarid,Nicolas Mounier,Eliane Gluckman,Gérard Socié,Jean Claude Ameisen

View Articletitled, CD95 engagement induces disseminated endothelial cell apoptosis in vivo: immunopathologic implications

Identification of a myeloid intrathymic pathway of dendritic cell development marked by expression of the granulocyte macrophage–colony-stimulating factor receptor

Virginia G. de Yébenes,Yolanda R. Carrasco,Almudena R. Ramiro,Marı́a L. Toribio

View Articletitled, Identification of a myeloid intrathymic pathway of dendritic cell development marked by expression of the granulocyte macrophage–colony-stimulating factor receptor

NEOPLASIA

The coiled-coil domain and Tyr177 of bcr are required to induce a murine chronic myelogenous leukemia–like disease by bcr/abl

Yiping He,Jason A. Wertheim,Lanwei Xu,Juli P. Miller,Fredrick G. Karnell,John K. Choi,Ruibao Ren,Warren S. Pear

View Articletitled, The coiled-coil domain and Tyr177 of bcr are required to induce a murine chronic myelogenous leukemia–like disease by bcr/abl

Involvement of protein kinase C and phosphatidylinositol 3–kinase pathways in the survival of B-cell chronic lymphocytic leukemia cells

Montserrat Barragán,Beatriz Bellosillo,Clara Campàs,Dolors Colomer,Gabriel Pons,Joan Gil

View Articletitled, Involvement of protein kinase C and phosphatidylinositol 3–kinase pathways in the survival of B-cell chronic lymphocytic leukemia cells

The chemokine receptor CCR7 and α4 integrin are important for migration of chronic lymphocytic leukemia cells into lymph nodes

Kathleen J. Till,Ke Lin,Mirko Zuzel,John C. Cawley

View Articletitled, The chemokine receptor CCR7 and α4 integrin are important for migration of chronic lymphocytic leukemia cells into lymph nodes

Recurring chromosomal abnormalities in leukemia inPML-RARA transgenic mice parallel human acute promyelocytic leukemia

Michelle M. Le Beau,Sheila Bitts,Elizabeth M. Davis,Scott C. Kogan

View Articletitled, Recurring chromosomal abnormalities in leukemia inPML-RARA transgenic mice parallel human acute promyelocytic leukemia

High frequency of leukemic clones in newborn screening blood samples of children with B-precursor acute lymphoblastic leukemia
Clinical Trials & Observations

Jeffrey W. Taub,Mark A. Konrad,Yubin Ge,John M. Naber,Jackie S. Scott,Larry H. Matherly,Yaddanapudi Ravindranath

View Articletitled, High frequency of leukemic clones in newborn screening blood samples of children with B-precursor acute lymphoblastic leukemia

PHAGOCYTES

Presence of a mobilizable intracellular pool of hepatocyte growth factor in human polymorphonuclear neutrophils

Alain Grenier,Sylvie Chollet-Martin,Bruno Crestani,Charlotte Delarche,Jamel El Benna,Anne Boutten,Valérie Andrieu,Geneviève Durand,Marie-Anne Gougerot-Pocidalo,Michel Aubier,Monique Dehoux

View Articletitled, Presence of a mobilizable intracellular pool of hepatocyte growth factor in human polymorphonuclear neutrophils

RED CELLS

Fetal and adult hemoglobin production during adult erythropoiesis: coordinate expression correlates with cell proliferation

Urszula Wojda,Pierre Noel,Jeffery L. Miller

View Articletitled, Fetal and adult hemoglobin production during adult erythropoiesis: coordinate expression correlates with cell proliferation

Longitudinal changes in brain magnetic resonance imaging findings in children with sickle cell disease

Charles H. Pegelow,Eric A. Macklin,Franklin G. Moser,Winfred C. Wang,Jacqueline A. Bello,Scott T. Miller,Elliott P. Vichinsky,Michael R. DeBaun,Ludovico Guarini,Robert A. Zimmerman,Donald P. Younkin,Dianne M. Gallagher,Thomas R. Kinney

View Articletitled, Longitudinal changes in brain magnetic resonance imaging findings in children with sickle cell disease

TRANSFUSION MEDICINE

HBED ligand: preclinical studies of a potential alternative to deferoxamine for treatment of chronic iron overload and acute iron poisoning

Raymond J. Bergeron,Jan Wiegand,Gary M. Brittenham

View Articletitled, HBED ligand: preclinical studies of a potential alternative to deferoxamine for treatment of chronic iron overload and acute iron poisoning

TRANSPLANTATION

The DBY gene codes for an HLA-DQ5–restricted human male-specific minor histocompatibility antigen involved in graft-versus-host disease

Mario H. J. Vogt,Joost W. van den Muijsenberg,Els Goulmy,Eric Spierings,Petra Kluck,Michel G. Kester,Ronald A. van Soest,Jan W. Drijfhout,Roel Willemze,J. H. Frederik Falkenburg

View Articletitled, The DBY gene codes for an HLA-DQ5–restricted human male-specific minor histocompatibility antigen involved in graft-versus-host disease

Activated eosinophils in upper gastrointestinal tract of patients with graft-versus-host disease

Marjan Daneshpouy,Gerard Socie,Marc Lemann,Jacqueline Rivet,Eliane Gluckman,Anne Janin

View Articletitled, Activated eosinophils in upper gastrointestinal tract of patients with graft-versus-host disease

Murine acute graft-versus-host disease can be prevented by depletion of alloreactive T lymphocytes using activation-induced cell death

Udo F. Hartwig,Michael Robbers,Claudia Wickenhauser,Christoph Huber

View Articletitled, Murine acute graft-versus-host disease can be prevented by depletion of alloreactive T lymphocytes using activation-induced cell death

Randomized study of valacyclovir as prophylaxis against cytomegalovirus reactivation in recipients of allogeneic bone marrow transplants

Per Ljungman,Rafael de la Camara,Noel Milpied,Liisa Volin,Charlotte A. Russell,Adam Crisp,Alison Webster,the Valacyclovir International Bone Marrow Transplant Study Group

View Articletitled, Randomized study of valacyclovir as prophylaxis against cytomegalovirus reactivation in recipients of allogeneic bone marrow transplants

BRIEF REPORTS

High-dose therapy and autologous blood stem cell transplantation in POEMS syndrome
Clinical Trials & Observations Brief Report

Arnaud Jaccard,Bruno Royer,Dominique Bordessoule,Jean-Claude Brouet,Jean-Paul Fermand

View Articletitled, High-dose therapy and autologous blood stem cell transplantation in POEMS syndrome

Loss of PU.1 expression is associated with defective immunoglobulin transcription in Hodgkin and Reed-Sternberg cells of classical Hodgkin disease
Brief Report

Franziska Jundt,Katharina Kley,Ioannis Anagnostopoulos,Kristina Schulze Pröbsting,Axel Greiner,Stephan Mathas,Claus Scheidereit,Thomas Wirth,Harald Stein,Bernd Dörken

View Articletitled, Loss of PU.1 expression is associated with defective immunoglobulin transcription in Hodgkin and Reed-Sternberg cells of classical Hodgkin disease

Homozygous factor V splice site mutation associated with severe factor V deficiency
Brief Report

Iris Schrijver,Marion A. Koerper,Carol D. Jones,James L. Zehnder

View Articletitled, Homozygous factor V splice site mutation associated with severe factor V deficiency

A novel mutation in the erythropoietin receptor gene is associated with familial erythrocytosis
Brief Report

Murat O. Arcasoy,Aysen F. Karayal,Harvey M. Segal,Joseph G. Sinning,Bernard G. Forget

View Articletitled, A novel mutation in the erythropoietin receptor gene is associated with familial erythrocytosis

CORRESPONDENCE

Measles in bone marrow transplant recipients

Jan Storek

View Articletitled, Measles in bone marrow transplant recipients

Treatment options in chronic myelogenous leukemia

Edward A. Copelan

View Articletitled, Treatment options in chronic myelogenous leukemia

The common pathways, but different outcomes, of apoptosis induced by extracorporeal photopheresis and in vivo chemotherapy may reinforce the important immunomodulatory effect of monocytes

John Bladon,Peter Taylor

View Articletitled, The common pathways, but different outcomes, of apoptosis induced by extracorporeal photopheresis and in vivo chemotherapy may reinforce the important immunomodulatory effect of monocytes

Multiple myeloma: illegitimate switch recombinations and their relation to chromosomal translocations

Helmut H. Schmidt

View Articletitled, Multiple myeloma: illegitimate switch recombinations and their relation to chromosomal translocations

Myelodysplastic syndromes: from French-American-British to World Health Organization: a commentary

John M. Bennett,Richard D. Brunning,James W. Vardiman

View Articletitled, Myelodysplastic syndromes: from French-American-British to World Health Organization: a commentary

Mutations of Chk2 in primary hematopoietic neoplasms

Akira Hangaishi,Seishi Ogawa,Ying Qiao,Lili Wang,Noriko Hosoya,Koichiro Yuji,Yoichi Imai,Kengo Takeuchi,Shuichi Miyawaki,Hisamaru Hirai

View Articletitled, Mutations of Chk2 in primary hematopoietic neoplasms

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Issue Archive

Table of Contents

INSIDE BLOOD

PLENARY PAPERS

REVIEW ARTICLES

CHEMOKINES

CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS

A humanized non–FcR-binding anti-CD3 antibody, visilizumab, for treatment of steroid-refractory acute graft-versus-host disease Clinical Trials & Observations

A prospective study of venous thromboembolism in relation to factor V Leiden and related factors Clinical Trials & Observations

Association of CD34 cell dose with hematopoietic recovery, infections, and other outcomes after HLA-identical sibling bone marrow transplantation Clinical Trials & Observations

Comparison of Escherichia coli–asparaginase withErwinia-asparaginase in the treatment of childhood lymphoid malignancies: results of a randomized European Organisation for Research and Treatment of Cancer—Children's Leukemia Group phase 3 trial Clinical Trials & Observations

HEMATOPOIESIS

Long-term support of hematopoiesis by a single stem cell clone in patients with paroxysmal nocturnal hemoglobinuria Clinical Trials & Observations

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

IMMUNOBIOLOGY

Flt3 ligand as a vaccine adjuvant in association with HER-2/neu peptide-based vaccines in patients with HER-2/neu–overexpressing cancers Clinical Trials & Observations

NEOPLASIA

High frequency of leukemic clones in newborn screening blood samples of children with B-precursor acute lymphoblastic leukemia Clinical Trials & Observations

PHAGOCYTES

RED CELLS

TRANSFUSION MEDICINE

TRANSPLANTATION

BRIEF REPORTS

High-dose therapy and autologous blood stem cell transplantation in POEMS syndrome Clinical Trials & Observations Brief Report

Loss of PU.1 expression is associated with defective immunoglobulin transcription in Hodgkin and Reed-Sternberg cells of classical Hodgkin disease Brief Report

Homozygous factor V splice site mutation associated with severe factor V deficiency Brief Report

A novel mutation in the erythropoietin receptor gene is associated with familial erythrocytosis Brief Report