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Volume 98, Issue 4

August 15 2001

In this Issue

INSIDE BLOOD
PLENARY PAPERS
REVIEW ARTICLES
ERRATA
CHEMOKINES
CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS
GENE THERAPY
HEMATOPOIESIS
HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY
IMMUNOBIOLOGY
NEOPLASIA
PHAGOCYTES
TRANSFUSION MEDICINE
TRANSPLANTATION
BRIEF REPORTS
CORRESPONDENCE

INSIDE BLOOD

Welcome to the era of interconnecting pathways

H. Phillip Koeffler

View Articletitled, Welcome to the era of interconnecting pathways

Mysteries of HIV pathogenesis explained

Steven Patterson

View Articletitled, Mysteries of HIV pathogenesis explained

PLENARY PAPERS

Granulocyte colony-stimulating factor regulates myeloid differentiation through CCAAT/enhancer-binding protein ε

Hideaki Nakajima,James N. Ihle

View Articletitled, Granulocyte colony-stimulating factor regulates myeloid differentiation through CCAAT/enhancer-binding protein ε

Depletion of circulating natural type 1 interferon-producing cells in HIV-infected AIDS patients

Vassili Soumelis,Iain Scott,Ferdous Gheyas,Damien Bouhour,Gregoire Cozon,Laurent Cotte,Laurence Huang,Jay A. Levy,Yong-Jun Liu

View Articletitled, Depletion of circulating natural type 1 interferon-producing cells in HIV-infected AIDS patients

REVIEW ARTICLES

Signaling pathways activated by daunorubicin

Guy Laurent,Jean-Pierre Jaffrézou

View Articletitled, Signaling pathways activated by daunorubicin

ERRATA

Erratum for vol. 97, p. 3589

View Articletitled, Erratum for vol. 97, p. 3589

Erratum for vol. 97, p. 2238

View Articletitled, Erratum for vol. 97, p. 2238

CHEMOKINES

Blocking of c-FLIP_L–independent cycloheximide-induced apoptosis or Fas-mediated apoptosis by the CC chemokine receptor 9/TECK interaction

Byung-S. Youn,Young J. Kim,Charlie Mantel,Kang-Yeol Yu,Hal E. Broxmeyer

View Articletitled, Blocking of c-FLIPL–independent cycloheximide-induced apoptosis or Fas-mediated apoptosis by the CC chemokine receptor 9/TECK interaction

CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS

T-cell–depleted allogeneic bone marrow transplantation followed by donor lymphocyte infusion in patients with multiple myeloma: induction of graft-versus-myeloma effect
Clinical Trials & Observations

Edwin Alyea,Edie Weller,Robert Schlossman,Christine Canning,Iain Webb,Deborah Doss,Peter Mauch,Karen Marcus,David Fisher,Andrea Freeman,Bijal Parikh,John Gribben,Robert Soiffer,Jerome Ritz,Kenneth Anderson

View Articletitled, T-cell–depleted allogeneic bone marrow transplantation followed by donor lymphocyte infusion in patients with multiple myeloma: induction of graft-versus-myeloma effect

Lack of correlation between numbers of circulating t(14;18)-positive cells and response to first-line treatment in follicular lymphoma
Clinical Trials & Observations

Caroline M. P. W. Mandigers,Jules P. P. Meijerink,Ewald J. B. M. Mensink,Evelyn L. R. T. M. Tönnissen,Konnie M. Hebeda,M. José J. T. Bogman,John M. M. Raemaekers,for the Interzol (South-East Netherlands Comprehensive Cancer Centers Cooperative Group)

View Articletitled, Lack of correlation between numbers of circulating t(14;18)-positive cells and response to first-line treatment in follicular lymphoma

Expression of a single gene, BCL-6, strongly predicts survival in patients with diffuse large B-cell lymphoma
Clinical Trials & Observations

Izidore S. Lossos,Carol D. Jones,Roger Warnke,Yasodha Natkunam,Herbert Kaizer,James L. Zehnder,Rob Tibshirani,Ronald Levy

View Articletitled, Expression of a single gene, BCL-6, strongly predicts survival in patients with diffuse large B-cell lymphoma

Rituximab chimeric anti-CD20 monoclonal antibody treatment for adults with chronic idiopathic thrombocytopenic purpura
Clinical Trials & Observations

Roberto Stasi,Adalberto Pagano,Elisa Stipa,Sergio Amadori

View Articletitled, Rituximab chimeric anti-CD20 monoclonal antibody treatment for adults with chronic idiopathic thrombocytopenic purpura

Thalidomide produces transfusion independence in long-standing refractory anemias of patients with myelodysplastic syndromes
Clinical Trials & Observations

Azra Raza,Peter Meyer,Diya Dutt,Francesca Zorat,Laurie Lisak,Fabiana Nascimben,Morne du Randt,Christopher Kaspar,Cathryn Goldberg,Jerome Loew,Saleem Dar,Sefer Gezer,Parameswaran Venugopal,Jerome Zeldis

View Articletitled, Thalidomide produces transfusion independence in long-standing refractory anemias of patients with myelodysplastic syndromes

The nonexpression of CD36 on reticulocytes and mature red blood cells does not modify the clinical course of patients with sickle cell anemia
Clinical Trials & Observations

Ketty Lee,Pierre Gane,Françoise Roudot-Thoraval,Bertand Godeau,Dora Bachir,Françoise Bernaudin,Jean-Pierre Cartron,Frédéric Galactéros,Philippe Bierling

View Articletitled, The nonexpression of CD36 on reticulocytes and mature red blood cells does not modify the clinical course of patients with sickle cell anemia

Epstein-Barr virus (EBV) reactivation is a frequent event after allogeneic stem cell transplantation (SCT) and quantitatively predicts EBV-lymphoproliferative disease following T-cell–depleted SCT
Clinical Trials & Observations

Joost W. J. van Esser,Bronno van der Holt,Ellen Meijer,Hubert G. M. Niesters,Rudolf Trenschel,Steven F. T. Thijsen,Anton M. van Loon,Francesco Frassoni,Andrea Bacigalupo,Ulrich W. Schaefer,Albert D. M. E. Osterhaus,Jan Willem Gratama,Bob Löwenberg,Leo F. Verdonck,Jan J. Cornelissen

View Articletitled, Epstein-Barr virus (EBV) reactivation is a frequent event after allogeneic stem cell transplantation (SCT) and quantitatively predicts EBV-lymphoproliferative disease following T-cell–depleted SCT

Diagnostic utility of flow cytometric immunophenotyping in myelodysplastic syndrome
Clinical Trials & Observations

Maryalice Stetler-Stevenson,Diane C. Arthur,Nicholas Jabbour,Xiu Y. Xie,Jeff Molldrem,A. John Barrett,David Venzon,Margaret E. Rick

View Articletitled, Diagnostic utility of flow cytometric immunophenotyping in myelodysplastic syndrome

Multidrug-resistance phenotype and clinical responses to gemtuzumab ozogamicin
Clinical Trials & Observations

Michael L. Linenberger,Tom Hong,David Flowers,Eric L. Sievers,Ted A. Gooley,John M. Bennett,Mark S. Berger,Lance H. Leopold,Frederick R. Appelbaum,Irwin D. Bernstein

View Articletitled, Multidrug-resistance phenotype and clinical responses to gemtuzumab ozogamicin

GENE THERAPY

The mononucleotide-dependent, nonantisense mechanism of action of phosphodiester and phosphorothioate oligonucleotides depends upon the activity of an ecto-5′-nucleotidase

Maria Koziolkiewicz,Edyta Gendaszewska,Maria Maszewska,C. A. Stein,Wojciech J. Stec

View Articletitled, The mononucleotide-dependent, nonantisense mechanism of action of phosphodiester and phosphorothioate oligonucleotides depends upon the activity of an ecto-5′-nucleotidase

HEMATOPOIESIS

Defective hematopoiesis and hepatic steatosis in mice with combined deficiencies of the genes encoding Fancc and Cu/Zn superoxide dismutase

Suzana Hadjur,Karen Ung,Louis Wadsworth,James Dimmick,Evica Rajcan-Separovic,Richard W. Scott,Manuel Buchwald,Frank R. Jirik

View Articletitled, Defective hematopoiesis and hepatic steatosis in mice with combined deficiencies of the genes encoding Fancc and Cu/Zn superoxide dismutase

An in vitro model of hematopoietic stem cell homing demonstrates rapid homing and maintenance of engraftable stem cells

Angela E. Frimberger,Allen I. Stering,Peter J. Quesenberry

View Articletitled, An in vitro model of hematopoietic stem cell homing demonstrates rapid homing and maintenance of engraftable stem cells

Thrombocytopenic c-mpl^−/− mice can produce a normal level of platelets after administration of 5-fluorouracil: the effect of age on the response: Presented in part at the 41st Annual Meeting of the American Society of Hematology, December 1999.⁵⁵

Jack Levin,Laurence Cocault,Corinne Demerens,Cécile Challier,Michèle Pauchard,Jacques Caen,Michèle Souyri

View Articletitled, Thrombocytopenic c-mpl−/− mice can produce a normal level of platelets after administration of 5-fluorouracil: the effect of age on the response: Presented in part at the 41st Annual Meeting of the American Society of Hematology, December 1999.55

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

Stromal cells expressing ephrin-B2 promote the growth and sprouting of ephrin-B2⁺ endothelial cells

Xiu-Qin Zhang,Nobuyuki Takakura,Yuichi Oike,Tomohisa Inada,Nicholas W. Gale,George D. Yancopoulos,Toshio Suda

View Articletitled, Stromal cells expressing ephrin-B2 promote the growth and sprouting of ephrin-B2+ endothelial cells

Platelet glycoprotein V binds to collagen and participates in platelet adhesion and aggregation

Sylvie Moog,Pierre Mangin,Nadège Lenain,Catherine Strassel,Catherine Ravanat,Simone Schuhler,Monique Freund,Martine Santer,Mark Kahn,Bernhard Nieswandt,Christian Gachet,Jean-Pierre Cazenave,François Lanza

View Articletitled, Platelet glycoprotein V binds to collagen and participates in platelet adhesion and aggregation

The inflammatory action of CD40 ligand (CD154) expressed on activated human platelets is temporally limited by coexpressed CD40

Volker Henn,Sabine Steinbach,Kerstin Büchner,Peter Presek,Richard A. Kroczek

View Articletitled, The inflammatory action of CD40 ligand (CD154) expressed on activated human platelets is temporally limited by coexpressed CD40

Variable protection of β3-integrin–deficient mice from thrombosis initiated by different mechanisms

Susan S. Smyth,Ernane D. Reis,Heikki Väänänen,Wen Zhang,Barry S. Coller

View Articletitled, Variable protection of β3-integrin–deficient mice from thrombosis initiated by different mechanisms

Identification of a region in glycoprotein IIIa involved in subunit association with glycoprotein IIb: further lessons from Iraqi-Jewish Glanzmann thrombasthenia

Rivka Yatuv,Nurit Rosenberg,Ariella Zivelin,Hava Peretz,Rima Dardik,Luba Trakhtenbrot,Uri Seligsohn

View Articletitled, Identification of a region in glycoprotein IIIa involved in subunit association with glycoprotein IIb: further lessons from Iraqi-Jewish Glanzmann thrombasthenia

IMMUNOBIOLOGY

Cross-presentation of tumor antigens by bone marrow–derived antigen-presenting cells is the dominant mechanism in the induction of T-cell tolerance during B-cell lymphoma progression

Eduardo M. Sotomayor,Ivan Borrello,Frédérique-Marie Rattis,Alex G. Cuenca,Jacob Abrams,Kevin Staveley-O'Carroll,Hyam I. Levitsky

View Articletitled, Cross-presentation of tumor antigens by bone marrow–derived antigen-presenting cells is the dominant mechanism in the induction of T-cell tolerance during B-cell lymphoma progression

Antiapoptotic mechanism of HIV protease inhibitors: preventing mitochondrial transmembrane potential loss

Barbara N. Phenix,Julian J. Lum,Zelin Nie,Jaime Sanchez-Dardon,Andrew D. Badley

View Articletitled, Antiapoptotic mechanism of HIV protease inhibitors: preventing mitochondrial transmembrane potential loss

Cdc42, Rac1, and the Wiskott-Aldrich syndrome protein are involved in the cytoskeletal regulation of B lymphocytes

Lisa Westerberg,Gediminas Greicius,Scott B. Snapper,Pontus Aspenström,Eva Severinson

View Articletitled, Cdc42, Rac1, and the Wiskott-Aldrich syndrome protein are involved in the cytoskeletal regulation of B lymphocytes

Therapeutic efficacy of intravenous immunoglobulin preparations depends on the immunoglobulin G dimers: studies in experimental immune thrombocytopenia

Jessica L. Teeling,Theo Jansen-Hendriks,Taco W. Kuijpers,Masja de Haas,Jan G. J. van de Winkel,C. Erik Hack,Wim K. Bleeker

View Articletitled, Therapeutic efficacy of intravenous immunoglobulin preparations depends on the immunoglobulin G dimers: studies in experimental immune thrombocytopenia

Age-related increase of frequency of a new, phenotypically distinct subpopulation of human peripheral blood T cells expressing lowered levels of CD4

Ewa Bryl,Magdalena Gazda,Jerzy Foerster,Jacek M. Witkowski

View Articletitled, Age-related increase of frequency of a new, phenotypically distinct subpopulation of human peripheral blood T cells expressing lowered levels of CD4

Tumor necrosis factor-α induces coordinated changes in major histocompatibility class I presentation pathway, resulting in increased stability of class I complexes at the cell surface

Kristian Hallermalm,Katzutake Seki,Chenhong Wei,Chiara Castelli,Licia Rivoltini,Rolf Kiessling,Jelena Levitskaya

View Articletitled, Tumor necrosis factor-α induces coordinated changes in major histocompatibility class I presentation pathway, resulting in increased stability of class I complexes at the cell surface

Quantitation of T-cell neogenesis in vivo after allogeneic bone marrow transplantation in adults

Ephraim P. Hochberg,Antoinette C. Chillemi,Catherine J. Wu,Donna Neuberg,Christine Canning,Kelly Hartman,Edwin P. Alyea,Robert J. Soiffer,Spyros A. Kalams,Jerome Ritz

View Articletitled, Quantitation of T-cell neogenesis in vivo after allogeneic bone marrow transplantation in adults

Peripheral blood stem cell allograft rejection mediated by CD4⁺ T lymphocytes recognizing a single mismatch at HLA-DPβ1*0901

Katharina Fleischhauer,Elisabetta Zino,Benedetta Mazzi,Elisabetta Sironi,Paolo Servida,Elisabetta Zappone,Elena Benazzi,Claudio Bordignon

View Articletitled, Peripheral blood stem cell allograft rejection mediated by CD4+ T lymphocytes recognizing a single mismatch at HLA-DPβ1*0901

Gene expression screening of human mast cells and eosinophils using high-density oligonucleotide probe arrays: abundant expression of major basic protein in mast cells

Toshiharu Nakajima,Kenji Matsumoto,Hajime Suto,Kazuko Tanaka,Motohiro Ebisawa,Hisashi Tomita,Keisuke Yuki,Toshio Katsunuma,Akira Akasawa,Ryoichi Hashida,Yuji Sugita,Hideoki Ogawa,Chisei Ra,Hirohisa Saito

View Articletitled, Gene expression screening of human mast cells and eosinophils using high-density oligonucleotide probe arrays: abundant expression of major basic protein in mast cells

Th2 polarization by Der p 1–pulsed monocyte-derived dendritic cells is due to the allergic status of the donors

Hamida Hammad,Anne-Sophie Charbonnier,Catherine Duez,Alain Jacquet,Geoffrey A. Stewart,André-Bernard Tonnel,Joël Pestel

View Articletitled, Th2 polarization by Der p 1–pulsed monocyte-derived dendritic cells is due to the allergic status of the donors

Configuration of human dendritic cell cytoskeleton by Rho GTPases, the WAS protein, and differentiation

Siobhan Burns,Adrian J. Thrasher,Michael P. Blundell,Laura Machesky,Gareth E. Jones

View Articletitled, Configuration of human dendritic cell cytoskeleton by Rho GTPases, the WAS protein, and differentiation

NEOPLASIA

Autocrine antiapoptotic stimulation of cultured adult T-cell leukemia cells by overexpression of the chemokine I-309

Tobias Ruckes,Domenica Saul,Jacques Van Snick,Olivier Hermine,Ralph Grassmann

View Articletitled, Autocrine antiapoptotic stimulation of cultured adult T-cell leukemia cells by overexpression of the chemokine I-309

Expression of functional lung resistance–related protein predicts poor outcome in adult T-cell leukemia

Nobuhito Ohno,Ayako Tani,Kimiharu Uozumi,Shuichi Hanada,Tatsuhiko Furukawa,Suminori Akiba,Tomoyuki Sumizawa,Atae Utsunomiya,Terukatsu Arima,Shin-ichi Akiyama

View Articletitled, Expression of functional lung resistance–related protein predicts poor outcome in adult T-cell leukemia

A leukemic stem cell with intrinsic drug efflux capacity in acute myeloid leukemia

Gerald G. Wulf,Rui-Yu Wang,Ingrid Kuehnle,Douglas Weidner,Frank Marini,Malcolm K. Brenner,Michael Andreeff,Margaret A. Goodell

View Articletitled, A leukemic stem cell with intrinsic drug efflux capacity in acute myeloid leukemia

Tumor cells of hairy cell leukemia express multiple clonally related immunoglobulin isotypes via RNA splicing

Francesco Forconi,Surinder S. Sahota,Donatella Raspadori,Christopher I. Mockridge,Francesco Lauria,Freda K. Stevenson

View Articletitled, Tumor cells of hairy cell leukemia express multiple clonally related immunoglobulin isotypes via RNA splicing

T(11;18)(q21;q21) is associated with advanced mucosa-associated lymphoid tissue lymphoma that expresses nuclear BCL10

Hongxiang Liu,Hongtao Ye,Ahmet Dogan,Renzo Ranaldi,Rifat A. Hamoudi,Italo Bearzi,Peter G. Isaacson,Ming-Qing Du

View Articletitled, T(11;18)(q21;q21) is associated with advanced mucosa-associated lymphoid tissue lymphoma that expresses nuclear BCL10

Loss of heterozygosity in childhood de novo acute myelogenous leukemia

David A. Sweetser,Chien-Shing Chen,Adam A. Blomberg,David A. Flowers,Patricia C. Galipeau,Michael T. Barrett,Nyla A. Heerema,Jonathan Buckley,William G. Woods,Irwin D. Bernstein,Brian J. Reid

View Articletitled, Loss of heterozygosity in childhood de novo acute myelogenous leukemia

The Kit-activating mutation D816V enhances stem cell factor–dependent chemotaxis

Marcia L. Taylor,Jaroslaw Dastych,Devinder Sehgal,Magnus Sundstrom,Gunnar Nilsson,Cem Akin,Rose G. Mage,Dean D. Metcalfe

View Articletitled, The Kit-activating mutation D816V enhances stem cell factor–dependent chemotaxis

The contribution of NF-κB activity to spontaneous proliferation and resistance to apoptosis in human T-cell leukemia virus type 1 Tax-induced tumors

Toni Portis,John C. Harding,Lee Ratner

View Articletitled, The contribution of NF-κB activity to spontaneous proliferation and resistance to apoptosis in human T-cell leukemia virus type 1 Tax-induced tumors

Unusual childhood extramedullary hematologic malignancy with natural killer cell properties that contains tropomyosin 4–anaplastic lymphoma kinase gene fusion

Sandra J. Meech,Loris McGavran,Lorrie F. Odom,Xiayuan Liang,Lynne Meltesen,Jacob Gump,Qi Wei,Soren Carlsen,Stephen P. Hunger

View Articletitled, Unusual childhood extramedullary hematologic malignancy with natural killer cell properties that contains tropomyosin 4–anaplastic lymphoma kinase gene fusion

Synthetic unmethylated cytosine-phosphate-guanosine oligodeoxynucleotides are potent stimulators of antileukemia responses in naive and bone marrow transplant recipients

Bruce R. Blazar,Arthur M. Krieg,Patricia A. Taylor

View Articletitled, Synthetic unmethylated cytosine-phosphate-guanosine oligodeoxynucleotides are potent stimulators of antileukemia responses in naive and bone marrow transplant recipients

PHAGOCYTES

Role of the liver in regulating numbers of circulating neutrophils

Jialan Shi,Gary E. Gilbert,Yoshihiro Kokubo,Takashi Ohashi

View Articletitled, Role of the liver in regulating numbers of circulating neutrophils

Molecular basis of biomaterial-mediated foreign body reactions

Wen-Jing Hu,John W. Eaton,Tatiana P. Ugarova,Liping Tang

View Articletitled, Molecular basis of biomaterial-mediated foreign body reactions

TRANSFUSION MEDICINE

Characterization of immunologic tolerance induced by transfusion of UV-B–irradiated allogeneic mononuclear leukocytes

Kuo-Jang Kao,Eileen S. Huang,Sandra Donahue

View Articletitled, Characterization of immunologic tolerance induced by transfusion of UV-B–irradiated allogeneic mononuclear leukocytes

TRANSPLANTATION

Host marrow stem cell potential and engraftability at varying times after low-dose whole-body irradiation

F. Marc Stewart,Suju Zhong,Jean-François Lambert,Gerald A. Colvin,Mehrdad Abedi,Mark S. Dooner,Christina I. McAuliffe,Han Wang,Chung Hsieh,Peter J. Quesenberry

View Articletitled, Host marrow stem cell potential and engraftability at varying times after low-dose whole-body irradiation

BRIEF REPORTS

Antibodies from patients with heparin-induced thrombocytopenia stimulate monocytic cells to express tissue factor and secrete interleukin-8
Brief Report

Gowthami M. Arepally,Irene M. Mayer

View Articletitled, Antibodies from patients with heparin-induced thrombocytopenia stimulate monocytic cells to express tissue factor and secrete interleukin-8

Levels of vascular endothelial growth factor are elevated in patients with obstructive sleep apnea–hypopnea syndrome
Brief Report

Shigehiko Imagawa,Yuji Yamaguchi,Masato Higuchi,Tomohiro Neichi,Yuichi Hasegawa,Harumi Y. Mukai,Norio Suzuki,Masayuki Yamamoto,Toshiro Nagasawa

View Articletitled, Levels of vascular endothelial growth factor are elevated in patients with obstructive sleep apnea–hypopnea syndrome

Natural history of congenital dyserythropoietic anemia type II
Brief Report

Achille Iolascon,Jean Delaunay,Sunitha N. Wickramasinghe,Silverio Perrotta,Maddalena Gigante,Clara Camaschella

View Articletitled, Natural history of congenital dyserythropoietic anemia type II

A novel δβ fusion gene expresses hemoglobin A (HbA) not Hb Lepore: Senegalese δ⁰β⁺thalassemia
Brief Report

Samia Zertal-Zidani,Rolande Ducrocq,Catherine Weil-Olivier,Jacques Elion,Rajagopal Krishnamoorthy

View Articletitled, A novel δβ fusion gene expresses hemoglobin A (HbA) not Hb Lepore: Senegalese δ0β+thalassemia

A novel gene, NSD1, is fused to NUP98 in the t(5;11)(q35;p15.5) in de novo childhood acute myeloid leukemia
Brief Report

Rina J. Jaju,Carrie Fidler,Oskar A. Haas,Amanda J. Strickson,Fiona Watkins,Kevin Clark,Nicholas C. P. Cross,Jan-Fang Cheng,Peter D. Aplan,Lyndal Kearney,Jacqueline Boultwood,James S. Wainscoat

View Articletitled, A novel gene, NSD1, is fused to NUP98 in the t(5;11)(q35;p15.5) in de novo childhood acute myeloid leukemia

SH2D1A mutations in Japanese males with severe Epstein-Barr virus–associated illnesses
Brief Report

Ryo Sumazaki,Hirokazu Kanegane,Maki Osaki,Takashi Fukushima,Masahiro Tsuchida,Hiroyoshi Matsukura,Kentaro Shinozaki,Hiroshi Kimura,Akira Matsui,Toshio Miyawaki

View Articletitled, SH2D1A mutations in Japanese males with severe Epstein-Barr virus–associated illnesses

CORRESPONDENCE

The t(4;14)(p16.3;q32) is strongly associated with chromosome 13 abnormalities in both multiple myeloma and monoclonal gammopathy of undetermined significance

Rafael Fonseca,Martin M. Oken,Philip R. Greipp,on behalf of the Eastern Cooperative Oncology Group Myeloma Group

View Articletitled, The t(4;14)(p16.3;q32) is strongly associated with chromosome 13 abnormalities in both multiple myeloma and monoclonal gammopathy of undetermined significance

Misleading information about ALIP and VEGF in myelodysplasia

Manzoor H. Mangi

View Articletitled, Misleading information about ALIP and VEGF in myelodysplasia

Pseudo Pelger-Huët anomaly in myelodysplastic syndrome: hyposegmented or apoptotic neutrophil?

Vilasini T. Shetty,Suneel D. Mundle,Azra Raza

View Articletitled, Pseudo Pelger-Huët anomaly in myelodysplastic syndrome: hyposegmented or apoptotic neutrophil?

Alternate designs for conduct and analysis of phase I cancer trials

Vincent Lévy,Sarah Zohar,Raphaël Porcher,Sylvie Chevret

View Articletitled, Alternate designs for conduct and analysis of phase I cancer trials

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Issue Archive

Table of Contents

INSIDE BLOOD

PLENARY PAPERS

REVIEW ARTICLES

ERRATA

CHEMOKINES

CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS

T-cell–depleted allogeneic bone marrow transplantation followed by donor lymphocyte infusion in patients with multiple myeloma: induction of graft-versus-myeloma effect Clinical Trials & Observations

Lack of correlation between numbers of circulating t(14;18)-positive cells and response to first-line treatment in follicular lymphoma Clinical Trials & Observations

Expression of a single gene, BCL-6, strongly predicts survival in patients with diffuse large B-cell lymphoma Clinical Trials & Observations

Rituximab chimeric anti-CD20 monoclonal antibody treatment for adults with chronic idiopathic thrombocytopenic purpura Clinical Trials & Observations

Thalidomide produces transfusion independence in long-standing refractory anemias of patients with myelodysplastic syndromes Clinical Trials & Observations

The nonexpression of CD36 on reticulocytes and mature red blood cells does not modify the clinical course of patients with sickle cell anemia Clinical Trials & Observations

Epstein-Barr virus (EBV) reactivation is a frequent event after allogeneic stem cell transplantation (SCT) and quantitatively predicts EBV-lymphoproliferative disease following T-cell–depleted SCT Clinical Trials & Observations

Diagnostic utility of flow cytometric immunophenotyping in myelodysplastic syndrome Clinical Trials & Observations

Multidrug-resistance phenotype and clinical responses to gemtuzumab ozogamicin Clinical Trials & Observations