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Volume 97, Issue 2

January 15 2001

In this Issue

INSIDE BLOOD
REVIEW ARTICLES
CHEMOKINES
CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS
GENE THERAPY
HEMATOPOIESIS
HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY
IMMUNOBIOLOGY
NEOPLASIA
RED CELLS
TRANSFUSION MEDICINE
TRANSPLANTATION
BRIEF REPORTS
CORRESPONDENCE

INSIDE BLOOD

High-dose therapy and ABMT for follicular lymphoma

James O. Armitage

View Articletitled, High-dose therapy and ABMT for follicular lymphoma

REVIEW ARTICLES

The intriguing role of polymorphonuclear neutrophils in antitumor reactions

Emma Di Carlo,Guido Forni,PierLuigi Lollini,Mario P. Colombo,Andrea Modesti,Piero Musiani

View Articletitled, The intriguing role of polymorphonuclear neutrophils in antitumor reactions

CHEMOKINES

Chemokine stromal cell-derived factor-1α modulates VLA-4 integrin-mediated multiple myeloma cell adhesion to CS-1/fibronectin and VCAM-1

Francisco Sanz-Rodrı́guez,Andrés Hidalgo,Joaquin Teixidó

View Articletitled, Chemokine stromal cell-derived factor-1α modulates VLA-4 integrin-mediated multiple myeloma cell adhesion to CS-1/fibronectin and VCAM-1

HIV-1 Tat promotes monocyte chemoattractant protein-1 secretion followed by transmigration of monocytes

In-Woo Park,Jian-Feng Wang,Jerome E. Groopman

View Articletitled, HIV-1 Tat promotes monocyte chemoattractant protein-1 secretion followed by transmigration of monocytes

Signal transduction involved in MCP-1–mediated monocytic transendothelial migration

Béatrice Cambien,Manuel Pomeranz,Marie-Ange Millet,Bernard Rossi,Annie Schmid-Alliana

View Articletitled, Signal transduction involved in MCP-1–mediated monocytic transendothelial migration

Expression and regulation of chemokine receptors in human natural killer cells

Marit Inngjerdingen,Bassam Damaj,Azzam A. Maghazachi

View Articletitled, Expression and regulation of chemokine receptors in human natural killer cells

CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS

Recombinant human granulocyte colony-stimulating factor therapy for patients with neutropenia and/or neutrophil dysfunction secondary to glycogen storage disease type 1b
Clinical Trials & Observations

Stanley Calderwood,Laurie Kilpatrick,Steven D. Douglas,Melvin Freedman,Kim Smith-Whitley,Martha Rolland,Joanne Kurtzberg

View Articletitled, Recombinant human granulocyte colony-stimulating factor therapy for patients with neutropenia and/or neutrophil dysfunction secondary to glycogen storage disease type 1b

The number of donor CD3⁺ cells is the most important factor for graft failure after allogeneic transplantation of CD34⁺ selected cells from peripheral blood from HLA-identical siblings
Clinical Trials & Observations

Alvaro Urbano-Ispizua,Ciril Rozman,Pedro Pimentel,Carlos Solano,Javier de la Rubia,Salut Brunet,Jaime Pérez-Oteiza,Christelle Ferrá,Javier Zuazu,Dolores Caballero,Alzira Carvalhais,Jose Luis Dı́ez,Ildefonso Espigado,Carmen Martı́nez,Fernando Campilho,Miguel Angel Sanz,Jorge Sierra,Javier Garcı́a-Conde,Emilio Montserrat,for the Spanish Group for Allogeneic Peripheral Blood Transplantation

View Articletitled, The number of donor CD3+ cells is the most important factor for graft failure after allogeneic transplantation of CD34+ selected cells from peripheral blood from HLA-identical siblings

Cidofovir for cytomegalovirus infection and disease in allogeneic stem cell transplant recipients
Clinical Trials & Observations

Per Ljungman,Giorgio Lambertenghi Deliliers,Uwe Platzbecker,Susanne Matthes-Martin,Andrea Bacigalupo,Hermann Einsele,Johanna Ullmann,Maurizio Musso,Rudolf Trenschel,Patricia Ribaud,Martin Bornhäuser,Simone Cesaro,Bruce Crooks,Adrian Dekker,Nicole Gratecos,Thomas Klingebiel,Elena Tagliaferri,Andrew J. Ullmann,Pierre Wacker,Catherine Cordonnier,for the Infectious Diseases Working Party of the European Group for Blood and Marrow Transplantation

View Articletitled, Cidofovir for cytomegalovirus infection and disease in allogeneic stem cell transplant recipients

Raised blast glutathione levels are associated with an increased risk of relapse in childhood acute lymphocytic leukemia
Clinical Trials & Observations

Pamela R. Kearns,Rob Pieters,M. M. Antoinette Rottier,Andrew D. J. Pearson,Andrew G. Hall

View Articletitled, Raised blast glutathione levels are associated with an increased risk of relapse in childhood acute lymphocytic leukemia

Long-term evaluation of the beneficial effect of subtotal splenectomy for management of hereditary spherocytosis
Clinical Trials & Observations

Brigitte Bader-Meunier,Frédéric Gauthier,Frédérique Archambaud,Thérèse Cynober,Francoise Miélot,Jean-Paul Dommergues,Josiane Warszawski,Narla Mohandas,Gil Tchernia

View Articletitled, Long-term evaluation of the beneficial effect of subtotal splenectomy for management of hereditary spherocytosis

High-dose therapy and autologous bone marrow transplantation for follicular lymphoma in first complete or partial remission: results of a phase II clinical trial
Clinical Trials & Observations

Sandra J. Horning,Robert S. Negrin,Richard T. Hoppe,Saul A. Rosenberg,Nelson J. Chao,Gwynn D. Long,B. William Brown,Karl G. Blume

View Articletitled, High-dose therapy and autologous bone marrow transplantation for follicular lymphoma in first complete or partial remission: results of a phase II clinical trial

GENE THERAPY

Second generation knockout sickle mice: the effect of HbF

Mary E. Fabry,Sandra M. Suzuka,Rona S. Weinberg,Christine Lawrence,Stephen M. Factor,John G. Gilman,Frank Costantini,Ronald L. Nagel

View Articletitled, Second generation knockout sickle mice: the effect of HbF

HEMATOPOIESIS

CD34 expression on long-term repopulating hematopoietic stem cells changes during developmental stages

Sahoko Matsuoka,Yasuhiro Ebihara,Ming-jiang Xu,Takefumi Ishii,Daisuke Sugiyama,Hiroshi Yoshino,Takahiro Ueda,Atsushi Manabe,Ryuhei Tanaka,Yasuo Ikeda,Tatsutoshi Nakahata,Kohichiro Tsuji

View Articletitled, CD34 expression on long-term repopulating hematopoietic stem cells changes during developmental stages

Human CD34⁺ stem cells express the hiwigene, a human homologue of the Drosophila genepiwi

Arun K. Sharma,Mary C. Nelson,John E. Brandt,Maija Wessman,Nadim Mahmud,Kevin P. Weller,Ronald Hoffman

View Articletitled, Human CD34+ stem cells express the hiwigene, a human homologue of the Drosophila genepiwi

Stromal cells retard the differentiation of CD34⁺CD38^low/neg human primitive progenitors exposed to cytokines independent of their mitotic history

Annelise Bennaceur-Griscelli,Corinne Pondarré,Valérie Schiavon,William Vainchenker,Laure Coulombel

View Articletitled, Stromal cells retard the differentiation of CD34+CD38low/neg human primitive progenitors exposed to cytokines independent of their mitotic history

Cessation of intensive treatment with recombinant human erythropoietin is followed by secondary anemia

Maude Piron,Martine Loo,André Gothot,Françoise Tassin,Georges Fillet,Yves Beguin

View Articletitled, Cessation of intensive treatment with recombinant human erythropoietin is followed by secondary anemia

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

Synthesis, secretion, and subcellular localization of serglycin proteoglycan in human endothelial cells

Barbara P. Schick,Joel F. Gradowski,James D. San Antonio

View Articletitled, Synthesis, secretion, and subcellular localization of serglycin proteoglycan in human endothelial cells

Circulating autoantibodies to oxidized cardiolipin correlate with isoprostane F_2α-VI levels and the extent of atherosclerosis in ApoE-deficient mice: modulation by vitamin E

Domenico Praticò,Rajendra K. Tangirala,Sohvi Hörkkö,Joseph L. Witztum,Wulf Palinski,Garret A. FitzGerald

View Articletitled, Circulating autoantibodies to oxidized cardiolipin correlate with isoprostane F2α-VI levels and the extent of atherosclerosis in ApoE-deficient mice: modulation by vitamin E

Interleukin 11 significantly increases plasma von Willebrand factor and factor VIII in wild type and von Willebrand disease mouse models

Cécile V. Denis,Kyubum Kwack,Simin Saffaripour,Srinivas Maganti,Patrick André,Robert G. Schaub,Denisa D. Wagner

View Articletitled, Interleukin 11 significantly increases plasma von Willebrand factor and factor VIII in wild type and von Willebrand disease mouse models

IMMUNOBIOLOGY

The soluble murine type I interferon receptor Ifnar-2 is present in serum, is independently regulated, and has both agonistic and antagonistic properties

Matthew P. Hardy,Catherine M. Owczarek,Suzana Trajanovska,Xiang Liu,Ismail Kola,Paul J. Hertzog

View Articletitled, The soluble murine type I interferon receptor Ifnar-2 is present in serum, is independently regulated, and has both agonistic and antagonistic properties

Autocrine interleukin-6 production and highly malignant multiple myeloma: relation with resistance to drug-induced apoptosis

Maria Antonia Frassanito,Antonio Cusmai,Giuseppe Iodice,Franco Dammacco

View Articletitled, Autocrine interleukin-6 production and highly malignant multiple myeloma: relation with resistance to drug-induced apoptosis

NEOPLASIA

Illegitimate switch recombinations are present in approximately half of primary myeloma tumors, but do not relate to known prognostic indicators or survival

P. Joy Ho,Ross D. Brown,Gregory J. Pelka,Antony Basten,John Gibson,Douglas E. Joshua

View Articletitled, Illegitimate switch recombinations are present in approximately half of primary myeloma tumors, but do not relate to known prognostic indicators or survival

Down-regulation of BOB.1/OBF.1 and Oct2 in classical Hodgkin disease but not in lymphocyte predominant Hodgkin disease correlates with immunoglobulin transcription

Harald Stein,Theresa Marafioti,Hans-Dieter Foss,Helmut Laumen,Michael Hummel,Ioannis Anagnostopoulos,Thomas Wirth,Gudrun Demel,Brunangelo Falini

View Articletitled, Down-regulation of BOB.1/OBF.1 and Oct2 in classical Hodgkin disease but not in lymphocyte predominant Hodgkin disease correlates with immunoglobulin transcription

JC-1: a very sensitive fluorescent probe to test Pgp activity in adult acute myeloid leukemia
Clinical Trials & Observations

Ollivier Legrand,Jean-Yves Perrot,Ghislaine Simonin,Marion Baudard,Jean-Pierre Marie

View Articletitled, JC-1: a very sensitive fluorescent probe to test Pgp activity in adult acute myeloid leukemia

Role for CCG-trinucleotide repeats in the pathogenesis of chronic lymphocytic leukemia

Rebecca L. Auer,Christopher Jones,Roman A. Mullenbach,Denise Syndercombe-Court,Donald W. Milligan,Christopher D. Fegan,Finbarr E. Cotter

View Articletitled, Role for CCG-trinucleotide repeats in the pathogenesis of chronic lymphocytic leukemia

Bone morphogenetic protein-4 inhibits proliferation and induces apoptosis of multiple myeloma cells: Presented in part at the 41st annual meeting of the American Society of Hematology, New Orleans, December 1999.

Öyvind Hjertner,Henrik Hjorth-Hansen,Magne Börset,Carina Seidel,Anders Waage,Anders Sundan

View Articletitled, Bone morphogenetic protein-4 inhibits proliferation and induces apoptosis of multiple myeloma cells: Presented in part at the 41st annual meeting of the American Society of Hematology, New Orleans, December 1999.

Interferon resistance of cutaneous T-cell lymphoma–derived clonal T-helper 2 cells allows selective viral replication

Reinhard Dummer,Udo Döbbeling,Ralf Geertsen,Jörg Willers,Günter Burg,Jovan Pavlovic

View Articletitled, Interferon resistance of cutaneous T-cell lymphoma–derived clonal T-helper 2 cells allows selective viral replication

Potent and specific antitumor effects of an anti-CD22–targeted cytotoxic ribonuclease: potential for the treatment of non-Hodgkin lymphoma

Dianne L. Newton,Hans J. Hansen,Stanislaw M. Mikulski,David M. Goldenberg,Susanna M. Rybak

View Articletitled, Potent and specific antitumor effects of an anti-CD22–targeted cytotoxic ribonuclease: potential for the treatment of non-Hodgkin lymphoma

RED CELLS

Chronic inborn erythrocytosis leads to cardiac dysfunction and premature death in mice overexpressing erythropoietin

Klaus F. Wagner,Dörthe M. Katschinski,Jo Hasegawa,Dunja Schumacher,Birgit Meller,Ulrich Gembruch,Uda Schramm,Wolfgang Jelkmann,Max Gassmann,Joachim Fandrey

View Articletitled, Chronic inborn erythrocytosis leads to cardiac dysfunction and premature death in mice overexpressing erythropoietin

Defective spectrin integrity and neonatal thrombosis in the first mouse model for severe hereditary elliptocytosis

Nancy J. Wandersee,Amanda N. Roesch,Nancy R. Hamblen,Joost de Moes,Martin A. van der Valk,Roderick T. Bronson,J. Aura Gimm,Narla Mohandas,Peter Demant,Jane E. Barker

View Articletitled, Defective spectrin integrity and neonatal thrombosis in the first mouse model for severe hereditary elliptocytosis

TRANSFUSION MEDICINE

Polyethylene glycol–coated red blood cells fail to bind glycophorin A–specific antibodies and are impervious to invasion by the Plasmodium falciparum malaria parasite

Douglas P. Blackall,Jonathan K. Armstrong,Herbert J. Meiselman,Timothy C. Fisher

View Articletitled, Polyethylene glycol–coated red blood cells fail to bind glycophorin A–specific antibodies and are impervious to invasion by the Plasmodium falciparum malaria parasite

TRANSPLANTATION

Allogeneic chimerism with low-dose irradiation, antigen presensitization, and costimulator blockade in H-2 mismatched mice

Peter J. Quesenberry,Suju Zhong,Han Wang,Marc Stewart

View Articletitled, Allogeneic chimerism with low-dose irradiation, antigen presensitization, and costimulator blockade in H-2 mismatched mice

Altered T-cell receptor + CD28-mediated signaling and blocked cell cycle progression in interleukin 10 and transforming growth factor-β–treated alloreactive T cells that do not induce graft-versus-host disease

Vassiliki A. Boussiotis,Zong-Ming Chen,Jay C. Zeller,William J. Murphy,Alla Berezovskaya,Satwant Narula,Maria G. Roncarolo,Bruce R. Blazar

View Articletitled, Altered T-cell receptor + CD28-mediated signaling and blocked cell cycle progression in interleukin 10 and transforming growth factor-β–treated alloreactive T cells that do not induce graft-versus-host disease

BRIEF REPORTS

Hemizygous p16^INK4A deletion in pediatric acute lymphoblastic leukemia predicts independent risk of relapse
Brief Report

Tina L. Carter,Paul M. Watt,Rolee Kumar,Paul R. Burton,Gregory H. Reaman,Harland N. Sather,David L. Baker,Ursula R. Kees

View Articletitled, Hemizygous p16INK4A deletion in pediatric acute lymphoblastic leukemia predicts independent risk of relapse

Accelerated telomere shortening in hematological lineages is limited to the first year following stem cell transplantation
Brief Report

Nathalie Rufer,Tim H. Brümmendorf,Bernard Chapuis,Claudine Helg,Peter M. Lansdorp,Eddy Roosnek

View Articletitled, Accelerated telomere shortening in hematological lineages is limited to the first year following stem cell transplantation

CORRESPONDENCE

Human A1 expression in acute myeloid leukemia and its relationship to Bcl-2 expression

Jan S. Moreb,James Zucali

View Articletitled, Human A1 expression in acute myeloid leukemia and its relationship to Bcl-2 expression

Ribosomal proteins S3a, S13, S16, and S24 are not mutated in patients with Diamond-Blackfan anemia

Radek Cmejla,Jana Blafkova,Tomas Stopka,Jaroslav Jelinek,Kveta Petrtylova,Dagmar Pospisilova

View Articletitled, Ribosomal proteins S3a, S13, S16, and S24 are not mutated in patients with Diamond-Blackfan anemia

Increased frequency of HLA-DRB1*1302 haplotype in patients with nonimmune chronic idiopathic neutropenia of adults

Helen A. Papadaki,George D. Eliopoulos,Stavroula A. Coulocheri,Maria Spyropoulou,Cathrin Stavropoulos-Giokas

View Articletitled, Increased frequency of HLA-DRB1*1302 haplotype in patients with nonimmune chronic idiopathic neutropenia of adults

CD15-expressing phagocytic plasma cells in a patient with multiple myeloma

Reyhan Diz Kucukkaya,Abdullah Hacihanefioglu,Mustafa Nuri Yenerel,Mehmet Turgut,Meliha Nalcaci,Huseyin Keskin,Seyhun Solakoglu,Gulderen Yanikkaya Demirel

View Articletitled, CD15-expressing phagocytic plasma cells in a patient with multiple myeloma

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Issue Archive

Table of Contents

INSIDE BLOOD

REVIEW ARTICLES

CHEMOKINES

CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS

Recombinant human granulocyte colony-stimulating factor therapy for patients with neutropenia and/or neutrophil dysfunction secondary to glycogen storage disease type 1b Clinical Trials & Observations

The number of donor CD3+ cells is the most important factor for graft failure after allogeneic transplantation of CD34+ selected cells from peripheral blood from HLA-identical siblings Clinical Trials & Observations

Cidofovir for cytomegalovirus infection and disease in allogeneic stem cell transplant recipients Clinical Trials & Observations

Raised blast glutathione levels are associated with an increased risk of relapse in childhood acute lymphocytic leukemia Clinical Trials & Observations

Long-term evaluation of the beneficial effect of subtotal splenectomy for management of hereditary spherocytosis Clinical Trials & Observations

High-dose therapy and autologous bone marrow transplantation for follicular lymphoma in first complete or partial remission: results of a phase II clinical trial Clinical Trials & Observations