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EDITORIALS

“How I treat”: a new style of clinical review article

Kenneth Kaushansky, MD

View Articletitled, “How I treat”: a new style of clinical review article

PLENARY PAPERS

Highly efficient gene transfer into cord blood nonobese diabetic/severe combined immunodeficiency repopulating cells by oncoretroviral vector particles pseudotyped with the feline endogenous retrovirus (RD114) envelope protein

Patrick F. Kelly,Jody Vandergriff,Amit Nathwani,Arthur W. Nienhuis,Elio F. Vanin

View Articletitled, Highly efficient gene transfer into cord blood nonobese diabetic/severe combined immunodeficiency repopulating cells by oncoretroviral vector particles pseudotyped with the feline endogenous retrovirus (RD114) envelope protein

PERSPECTIVES

A ligand-receptor signaling threshold model of stem cell differentiation control: a biologically conserved mechanism applicable to hematopoiesis

Peter W. Zandstra,Douglas A. Lauffenburger,Connie J. Eaves

View Articletitled, A ligand-receptor signaling threshold model of stem cell differentiation control: a biologically conserved mechanism applicable to hematopoiesis

HOW I TREAT

How I treat patients with thrombotic thrombocytopenic purpura–hemolytic uremic syndrome
Clinical Trials & Observations

James N. George

View Articletitled, How I treat patients with thrombotic thrombocytopenic purpura–hemolytic uremic syndrome

CHEMOKINES

CXC chemokine receptor 3 expression on CD34⁺hematopoietic progenitors from human cord blood induced by granulocyte-macrophage colony-stimulating factor: chemotaxis and adhesion induced by its ligands, interferon γ–inducible protein 10 and monokine induced by interferon γ

Tan Jinquan,Sha Quan,Henrik H. Jacobi,Chen Jing,Anders Millner,Bettina Jensen,Hans O. Madsen,Lars P. Ryder,Arne Svejgaard,Hans-Jørgen Malling,Per S. Skov,Lars K. Poulsen

View Articletitled, CXC chemokine receptor 3 expression on CD34+hematopoietic progenitors from human cord blood induced by granulocyte-macrophage colony-stimulating factor: chemotaxis and adhesion induced by its ligands, interferon γ–inducible protein 10 and monokine induced by interferon γ

CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS

Nonmyeloablative stem cell transplantation for congenital immunodeficiencies
Clinical Trials & Observations

Persis Amrolia,Hubert B. Gaspar,Amel Hassan,David Webb,Alison Jones,Natalie Sturt,Giorgina Mieli-Vergani,Antonio Pagliuca,Ghulam Mufti,Nedim Hadzic,Graham Davies,Paul Veys

View Articletitled, Nonmyeloablative stem cell transplantation for congenital immunodeficiencies

Definition of relapse risk and role of nonanthracycline drugs for consolidation in patients with acute promyelocytic leukemia: a joint study of the PETHEMA and GIMEMA cooperative groups: Presented in part at the 41st meeting of the American Society of Hematology, New Orleans, LA, December 3-7, 1999.
Clinical Trials & Observations

View Articletitled, Definition of relapse risk and role of nonanthracycline drugs for consolidation in patients with acute promyelocytic leukemia: a joint study of the PETHEMA and GIMEMA cooperative groups: Presented in part at the 41st meeting of the American Society of Hematology, New Orleans, LA, December 3-7, 1999.

Effect of postremission chemotherapy before human leukocyte antigen–identical sibling transplantation for acute myelogenous leukemia in first complete remission
Clinical Trials & Observations

Martin S. Tallman,Philip A. Rowlings,Gustavo Milone,Mei-Jie Zhang,Waleska S. Perez,Daniel Weisdorf,Armand Keating,Robert Peter Gale,Robert B. Geller,Mary J. Laughlin,Hillard M. Lazarus,Selina M. Luger,Philip L. McCarthy,Jacob M. Rowe,Ruben A. Saez,Marcus R. Vowels,Mary M. Horowitz

View Articletitled, Effect of postremission chemotherapy before human leukocyte antigen–identical sibling transplantation for acute myelogenous leukemia in first complete remission

Radioimmunotherapy with iodine ¹³¹I tositumomab for relapsed or refractory B-cell non-Hodgkin lymphoma: updated results and long-term follow-up of the University of Michigan experience
Clinical Trials & Observations

Mark S. Kaminski,Judith Estes,Kenneth R. Zasadny,Isaac R. Francis,Charles W. Ross,Melissa Tuck,Denise Regan,Susan Fisher,Jeanne Gutierrez,Stewart Kroll,Robert Stagg,George Tidmarsh,Richard L. Wahl

View Articletitled, Radioimmunotherapy with iodine 131I tositumomab for relapsed or refractory B-cell non-Hodgkin lymphoma: updated results and long-term follow-up of the University of Michigan experience

Soluble stem cell factor receptor (CD117) and IL-2 receptor alpha chain (CD25) levels in the plasma of patients with mastocytosis: relationships to disease severity and bone marrow pathology
Clinical Trials & Observations

Cem Akin,Lawrence B. Schwartz,Takashi Kitoh,Hirokazu Obayashi,Alexandra S. Worobec,Linda M. Scott,Dean D. Metcalfe

View Articletitled, Soluble stem cell factor receptor (CD117) and IL-2 receptor alpha chain (CD25) levels in the plasma of patients with mastocytosis: relationships to disease severity and bone marrow pathology

B7-2–positive myeloma: incidence, clinical characteristics, prognostic significance, and implications for tumor immunotherapy
Clinical Trials & Observations

Belinda Pope,Ross D. Brown,John Gibson,Edna Yuen,Doug Joshua

View Articletitled, B7-2–positive myeloma: incidence, clinical characteristics, prognostic significance, and implications for tumor immunotherapy

Prognostic factors and treatment outcome in primary progressive Hodgkin lymphoma: a report from the German Hodgkin Lymphoma Study Group
Clinical Trials & Observations

Andreas Josting,Ulrich Rueffer,Jeremy Franklin,Markus Sieber,Volker Diehl,Andreas Engert

View Articletitled, Prognostic factors and treatment outcome in primary progressive Hodgkin lymphoma: a report from the German Hodgkin Lymphoma Study Group

A new morphologic classification system for acute promyelocytic leukemia distinguishes cases with underlyingPLZF/RARA gene rearrangements
Clinical Trials & Observations

Danielle Sainty,Vincenzo Liso,Angelo Cantù-Rajnoldi,David Head,Marie-Joëlle Mozziconacci,Christine Arnoulet,Laurence Benattar,Susanna Fenu,Marco Mancini,Eliane Duchayne,François-Xavier Mahon,Norma Gutierrez,Françoise Birg,Andrea Biondi,David Grimwade,Marina Lafage-Pochitaloff,Anne Hagemeijer,Georges Flandrin,on behalf of Groupe Français d'Hématologie Cellulaire, Groupe Français de Cytogénétique Hématologique, UK Cancer Cytogenetics Group, and BIOMED 1 European Community-Concerted Action “Molecular Cytogenetic Diagnosis in Haematological Malignancies”

View Articletitled, A new morphologic classification system for acute promyelocytic leukemia distinguishes cases with underlyingPLZF/RARA gene rearrangements

Characterization of acute promyelocytic leukemia cases lacking the classic t(15;17): results of the European Working Party
Clinical Trials & Observations

View Articletitled, Characterization of acute promyelocytic leukemia cases lacking the classic t(15;17): results of the European Working Party

ERRATA

Erratum in Nakayama et al. Vascular endothelial growth factor synergistically enhances bone morphogenetic protein-4-dependent lymphohematopoietic cell generation from embryonic stem cells in vitro. Blood. 2000;95:2275-2283.

View Articletitled, Erratum in Nakayama et al. Vascular endothelial growth factor synergistically enhances bone morphogenetic protein-4-dependent lymphohematopoietic cell generation from embryonic stem cells in vitro. Blood. 2000;95:2275-2283.

GENE THERAPY

Lentiviral-mediated gene transfer into human lymphocytes: role of HIV-1 accessory proteins

Dhanalakshmi Chinnasamy,Nachimuthu Chinnasamy,Melissa J. Enriquez,Makoto Otsu,Richard A. Morgan,Fabio Candotti

View Articletitled, Lentiviral-mediated gene transfer into human lymphocytes: role of HIV-1 accessory proteins

Lentiviral vectors for efficient delivery of CD80 and granulocyte-macrophage– colony-stimulating factor in human acute lymphoblastic leukemia and acute myeloid leukemia cells to induce antileukemic immune responses

Renata Stripecke,Angelo A. Cardoso,Karen A. Pepper,Dianne C. Skelton,Xiao-Jin Yu,Leo Mascarenhas,Kenneth I. Weinberg,Lee M. Nadler,Donald B. Kohn

View Articletitled, Lentiviral vectors for efficient delivery of CD80 and granulocyte-macrophage– colony-stimulating factor in human acute lymphoblastic leukemia and acute myeloid leukemia cells to induce antileukemic immune responses

Dendritic cells transduced by multiply deleted HIV-1 vectors exhibit normal phenotypes and functions and elicit an HIV-specific cytotoxic T-lymphocyte response in vitro: Presented in part at the 1999 International Meeting of the Institute of Human Virology, Baltimore, MD, August 28- September 2, 1999 (J Hum Virol 2: abstract 301, 1999).

Andreas Gruber,June Kan-Mitchell,Kelli L. Kuhen,Tetsu Mukai,Flossie Wong-Staal

View Articletitled, Dendritic cells transduced by multiply deleted HIV-1 vectors exhibit normal phenotypes and functions and elicit an HIV-specific cytotoxic T-lymphocyte response in vitro: Presented in part at the 1999 International Meeting of the Institute of Human Virology, Baltimore, MD, August 28- September 2, 1999 (J Hum Virol 2: abstract 301, 1999).

Mild preconditioning and low-level engraftment confer methotrexate resistance in mice transplanted with marrow expressing drug-resistant dihydrofolate reductase activity

Rohaizah I. James,Christopher A. Warlick,Miechaleen D. Diers,Roland Gunther,R. Scott McIvor

View Articletitled, Mild preconditioning and low-level engraftment confer methotrexate resistance in mice transplanted with marrow expressing drug-resistant dihydrofolate reductase activity

HEMATOPOIESIS

Pathologic interaction between megakaryocytes and polymorphonuclear leukocytes in myelofibrosis

Alain Schmitt,Hélène Jouault,Josette Guichard,Françoise Wendling,Arnaud Drouin,Elisabeth M. Cramer

View Articletitled, Pathologic interaction between megakaryocytes and polymorphonuclear leukocytes in myelofibrosis

Identification of a GATA-overlapping sequence within the enhancer of the murine GPIIb promoter that induces transcriptional deregulation in human K562 cells

Patricia Albanese,Marylène Leboeuf,Jean-Philippe Rosa,Georges Uzan

View Articletitled, Identification of a GATA-overlapping sequence within the enhancer of the murine GPIIb promoter that induces transcriptional deregulation in human K562 cells

Myeloid differentiation of FdCP1 cells is dependent on Stat5 processing

Flavia Piazza,Jason Valens,Eric Lagasse,Christian Schindler

View Articletitled, Myeloid differentiation of FdCP1 cells is dependent on Stat5 processing

Hematopoietic-specific β1 tubulin participates in a pathway of platelet biogenesis dependent on the transcription factor NF-E2

Patrick Lecine,Joseph E. Italiano, Jr,Sang-We Kim,Jean-Luc Villeval,Ramesh A. Shivdasani

View Articletitled, Hematopoietic-specific β1 tubulin participates in a pathway of platelet biogenesis dependent on the transcription factor NF-E2

Distinct functional properties of highly purified hematopoietic stem cells from mouse strains differing in stem cell numbers

Gerald de Haan,Stephen J. Szilvassy,Todd E. Meyerrose,Bert Dontje,Barry Grimes,Gary Van Zant

View Articletitled, Distinct functional properties of highly purified hematopoietic stem cells from mouse strains differing in stem cell numbers

Homing and engraftment potential of Sca-1⁺lin⁻ cells fractionated on the basis of adhesion molecule expression and position in cell cycle

Christie M. Orschell-Traycoff,Kelly Hiatt,Ramzi N. Dagher,Susan Rice,Mervin C. Yoder,Edward F. Srour

View Articletitled, Homing and engraftment potential of Sca-1+lin− cells fractionated on the basis of adhesion molecule expression and position in cell cycle

Intramedullary apoptosis of hematopoietic cells in myelodysplastic syndrome patients can be massive: apoptotic cells recovered from high-density fraction of bone marrow aspirates

Vilasini Shetty,Seema Hussaini,LaTanya Broady-Robinson,Krishnan Allampallam,Suneel Mundle,Raphael Borok,Eileen Broderick,Lucia Mazzoran,Francesca Zorat,Azra Raza

View Articletitled, Intramedullary apoptosis of hematopoietic cells in myelodysplastic syndrome patients can be massive: apoptotic cells recovered from high-density fraction of bone marrow aspirates

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

The α-defensins stimulate proteoglycan-dependent catabolism of low-density lipoprotein by vascular cells: a new class of inflammatory apolipoprotein and a possible contributor to atherogenesis

Abd Al-Roof Higazi,Taher Nassar,Tomas Ganz,Daniel J. Rader,Raphael Udassin,Khalil Bdeir,Edna Hiss,Bruce S. Sachais,Kevin Jon Williams,Eran Leitersdorf,Douglas B. Cines

View Articletitled, The α-defensins stimulate proteoglycan-dependent catabolism of low-density lipoprotein by vascular cells: a new class of inflammatory apolipoprotein and a possible contributor to atherogenesis

Thrombasthenic mice generated by replacement of the integrin α_IIb gene: demonstration that transcriptional activation of this megakaryocytic locus precedes lineage commitment

Diana Tronik-Le Roux,Valérie Roullot,Christel Poujol,Thierry Kortulewski,Paquita Nurden,Gérard Marguerie

View Articletitled, Thrombasthenic mice generated by replacement of the integrin αIIb gene: demonstration that transcriptional activation of this megakaryocytic locus precedes lineage commitment

Platelet endothelial cell adhesion molecule-1 (PECAM-1) is a target glycoprotein in drug-induced thrombocytopenia

Hartmut Kroll,Qi-Hong Sun,Sentot Santoso

View Articletitled, Platelet endothelial cell adhesion molecule-1 (PECAM-1) is a target glycoprotein in drug-induced thrombocytopenia

The cJun N-terminal kinase (JNK) signaling pathway mediates induction of urokinase-type plasminogen activator (uPA) by the alkylating agent MNNG

Maribel Parra,Frederic Lluı́s,Francesc Miralles,Carme Caelles,Pura Muñoz-Cánoves

View Articletitled, The cJun N-terminal kinase (JNK) signaling pathway mediates induction of urokinase-type plasminogen activator (uPA) by the alkylating agent MNNG

Recombinant staphylokinase variants with reduced antigenicity due to elimination of B-lymphocyte epitopes

Yves Laroche,Stephane Heymans,Sophie Capaert,Frans De Cock,Eddy Demarsin,Désiré Collen

View Articletitled, Recombinant staphylokinase variants with reduced antigenicity due to elimination of B-lymphocyte epitopes

Platelet adhesion to collagen in healthy volunteers is influenced by variation of both α₂β₁ density and von Willebrand factor
Clinical Trials & Observations

Mark Roest,Jan J. Sixma,Ya-Ping Wu,Martin J. W. Ijsseldijk,Mariëlle Tempelman,Pieter J. Slootweg,Philip G. de Groot,G. Henrita van Zanten

View Articletitled, Platelet adhesion to collagen in healthy volunteers is influenced by variation of both α2β1 density and von Willebrand factor

HIV-1 gp120- and gp160-induced apoptosis in cultured endothelial cells is mediated by caspases

Christina K. Ullrich,Jerome E. Groopman,Ramesh K. Ganju

View Articletitled, HIV-1 gp120- and gp160-induced apoptosis in cultured endothelial cells is mediated by caspases

Combinations of 4 mutations (FV R506Q, FV H1299R, FV Y1702C, PT 20210G/A) affecting the prothrombinase complex in a thrombophilic family
Clinical Trials & Observations

Elisabetta Castoldi,Paolo Simioni,Michael Kalafatis,Barbara Lunghi,Daniela Tormene,Domenico Girelli,Antonio Girolami,Francesco Bernardi

View Articletitled, Combinations of 4 mutations (FV R506Q, FV H1299R, FV Y1702C, PT 20210G/A) affecting the prothrombinase complex in a thrombophilic family

IMMUNOBIOLOGY

SHIP inhibits Akt activation in B cells through regulation of Akt membrane localization

Deborah Jeannean Carver,Mohammad Javad Aman,Kodimangalam S. Ravichandran

View Articletitled, SHIP inhibits Akt activation in B cells through regulation of Akt membrane localization

Cloning of human early B-cell factor and identification of target genes suggest a conserved role in B-cell development in man and mouse

Ramiro Gisler,Sten Erik W. Jacobsen,Mikael Sigvardsson

View Articletitled, Cloning of human early B-cell factor and identification of target genes suggest a conserved role in B-cell development in man and mouse

Coadministration of interleukin-18 and interleukin-12 induces a fatal inflammatory response in mice: critical role of natural killer cell interferon-γ production and STAT-mediated signal transduction

William E. Carson,Julie E. Dierksheide,Saad Jabbour,Mirela Anghelina,Page Bouchard,George Ku,Haixin Yu,Heinz Baumann,Manisha H. Shah,Megan A. Cooper,Joan Durbin,Michael A. Caligiuri

View Articletitled, Coadministration of interleukin-18 and interleukin-12 induces a fatal inflammatory response in mice: critical role of natural killer cell interferon-γ production and STAT-mediated signal transduction

Simian immunodeficiency virus-specific cytotoxic T lymphocytes and cell-associated viral RNA levels in distinct lymphoid compartments of SIVmac-infected rhesus monkeys

Marcelo J. Kuroda,Jörn E. Schmitz,Aruna Seth,Ronald S. Veazey,Christine E. Nickerson,Michelle A. Lifton,Peter J. Dailey,Meryl A. Forman,Paul Racz,Klara Tenner-Racz,Norman L. Letvin

View Articletitled, Simian immunodeficiency virus-specific cytotoxic T lymphocytes and cell-associated viral RNA levels in distinct lymphoid compartments of SIVmac-infected rhesus monkeys

Immunity to WT1 in the animal model and in patients with acute myeloid leukemia

Alexander Gaiger,Valerie Reese,Mary L. Disis,Martin A. Cheever

View Articletitled, Immunity to WT1 in the animal model and in patients with acute myeloid leukemia

Histone deacetylase inhibitors suppress IL-2–mediated gene expression prior to induction of apoptosis

Yuko Koyama,Masaaki Adachi,Masuo Sekiya,Mutsuhiro Takekawa,Kohzoh Imai

View Articletitled, Histone deacetylase inhibitors suppress IL-2–mediated gene expression prior to induction of apoptosis

NEOPLASIA

Gene expression networks underlying retinoic acid–induced differentiation of acute promyelocytic leukemia cells

Ting-Xi Liu,Ji-Wang Zhang,Jiong Tao,Ruo-Bo Zhang,Qing-Hua Zhang,Chun-Jun Zhao,Jian-Hua Tong,Michel Lanotte,Samuel Waxman,Sai-Juan Chen,Mao Mao,Geng-Xi Hu,Li Zhu,Zhu Chen

View Articletitled, Gene expression networks underlying retinoic acid–induced differentiation of acute promyelocytic leukemia cells

High incidence of chromosome 13 deletion in multiple myeloma detected by multiprobe interphase FISH

John Shaughnessy, Jr,Erming Tian,Jeffrey Sawyer,Klaus Bumm,Reid Landes,Ashraf Badros,Christopher Morris,Guido Tricot,Joshua Epstein,Bart Barlogie

View Articletitled, High incidence of chromosome 13 deletion in multiple myeloma detected by multiprobe interphase FISH

Antileukemic efficacy of 2′-deoxycoformycin in monocytic leukemia cells

Nozomi Niitsu,Yuri Yamamoto-Yamaguchi,Takashi Kasukabe,Junko Okabe-Kado,Masanori Umeda,Yoshio Honma

View Articletitled, Antileukemic efficacy of 2′-deoxycoformycin in monocytic leukemia cells

High incidence of alternatively spliced forms of deoxycytidine kinase in patients with resistant acute myeloid leukemia

Marjan J. T. Veuger,M. Willy Honders,Jim E. Landegent,Roel Willemze,Renée M. Y. Barge

View Articletitled, High incidence of alternatively spliced forms of deoxycytidine kinase in patients with resistant acute myeloid leukemia

Arsenic trioxide induces dose- and time-dependent apoptosis of endothelium and may exert an antileukemic effect via inhibition of angiogenesis

Gail J. Roboz,Sergio Dias,George Lam,William J. Lane,Steven L. Soignet,Raymond P. Warrell, Jr,Shahin Rafii

View Articletitled, Arsenic trioxide induces dose- and time-dependent apoptosis of endothelium and may exert an antileukemic effect via inhibition of angiogenesis

PML/RARα fusion protein expression in normal human hematopoietic progenitors dictates myeloid commitment and the promyelocytic phenotype

Francesco Grignani,Mauro Valtieri,Marco Gabbianelli,Vania Gelmetti,Rosanna Botta,Luisella Luchetti,Barbara Masella,Ornella Morsilli,Elvira Pelosi,Paola Samoggia,Pier Giuseppe Pelicci,Cesare Peschle

View Articletitled, PML/RARα fusion protein expression in normal human hematopoietic progenitors dictates myeloid commitment and the promyelocytic phenotype

PHAGOCYTES

Peyer's patch eosinophils: identification, characterization, and regulation by mucosal allergen exposure, interleukin-5, and eotaxin

Anil Mishra,Simon P. Hogan,Eric B. Brandt,Marc E. Rothenberg

View Articletitled, Peyer's patch eosinophils: identification, characterization, and regulation by mucosal allergen exposure, interleukin-5, and eotaxin

RED CELLS

Mutations in the iron-sulfur cluster ligands of the human ferrochelatase lead to erythropoietic protoporphyria

Xiaoye Schneider-Yin,Laurent Gouya,Morna Dorsey,Urszula Rüfenacht,Jean-Charles Deybach,Glória C. Ferreira

View Articletitled, Mutations in the iron-sulfur cluster ligands of the human ferrochelatase lead to erythropoietic protoporphyria

Sequential phosphorylation of protein band 3 by Syk and Lyn tyrosine kinases in intact human erythrocytes: identification of primary and secondary phosphorylation sites

Anna Maria Brunati,Luciana Bordin,Giulio Clari,Peter James,Manfredo Quadroni,Elisabetta Baritono,Lorenzo A. Pinna,Arianna Donella-Deana

View Articletitled, Sequential phosphorylation of protein band 3 by Syk and Lyn tyrosine kinases in intact human erythrocytes: identification of primary and secondary phosphorylation sites

Epolones induce erythropoietin expression via hypoxia-inducible factor-1α activation

Roger M. Wanner,Patrick Spielmann,Deborah M. Stroka,Gieri Camenisch,Isabelle Camenisch,Annette Scheid,David R. Houck,Christian Bauer,Max Gassmann,Roland H. Wenger

View Articletitled, Epolones induce erythropoietin expression via hypoxia-inducible factor-1α activation

TRANSFUSION MEDICINE

Molecular heterogeneity of the Jk_null phenotype: expression analysis of the Jk(S291P) mutation found in Finns

Frederic Sidoux-Walter,Nicole Lucien,Riikka Nissinen,Pertti Sistonen,Stephen Henry,Joann Moulds,Jean-Pierre Cartron,Pascal Bailly

View Articletitled, Molecular heterogeneity of the Jknull phenotype: expression analysis of the Jk(S291P) mutation found in Finns

Blood group A and B antigens are strongly expressed on platelets of some individuals

Brian R. Curtis,Jennifer T. Edwards,Martin J. Hessner,John P. Klein,Richard H. Aster

View Articletitled, Blood group A and B antigens are strongly expressed on platelets of some individuals

BRIEF REPORTS

Hydroxyurea-induced marked oscillations of platelet counts in patients with polycythemia vera
Brief Report

Ayalew Tefferi,Michelle A. Elliott,Pai Chih Kao,Sooyoung Yoon,Ihab El-Hemaidi,Thomas C. Pearson

View Articletitled, Hydroxyurea-induced marked oscillations of platelet counts in patients with polycythemia vera

Somatic mosaicism and compound heterozygosity in female hemophilia B
Brief Report

Jean-Marc Costa,Dominique Vidaud,Ingrid Laurendeau,Michel Vidaud,Edith Fressinaud,Jean-Pierre Moisan,Albert David,Dominique Meyer,Jean-Maurice Lavergne

View Articletitled, Somatic mosaicism and compound heterozygosity in female hemophilia B

Reassessment of interactions between hematopoietic receptors using common beta-chain and interleukin-3–specific receptor beta-chain–null cells: no evidence of functional interactions with receptors for erythropoietin, granulocyte colony-stimulating factor, or stem cell factor
Brief Report

Clare L. Scott,Lorraine Robb,Bette Papaevangeliou,Rachel Mansfield,Nicos A. Nicola,C. Glenn Begley

View Articletitled, Reassessment of interactions between hematopoietic receptors using common beta-chain and interleukin-3–specific receptor beta-chain–null cells: no evidence of functional interactions with receptors for erythropoietin, granulocyte colony-stimulating factor, or stem cell factor

Polarized expression of bone morphogenetic protein-4 in the human aorta-gonad-mesonephros region
Brief Report

Caroline J. Marshall,Christine Kinnon,Adrian J. Thrasher

View Articletitled, Polarized expression of bone morphogenetic protein-4 in the human aorta-gonad-mesonephros region

Coagulation and fibrinolytic activities in 2 siblings with β₂-glycoprotein I deficiency
Brief Report

Rie Takeuchi,Tatsuya Atsumi,Masahiro Ieko,Hiroyuki Takeya,Shinsuke Yasuda,Kenji Ichikawa,Akito Tsutsumi,Koji Suzuki,Takao Koike

View Articletitled, Coagulation and fibrinolytic activities in 2 siblings with β2-glycoprotein I deficiency

Human erythrocyte pyrimidine 5′-nucleotidase, PN-I, is identical to p36, a protein associated to lupus inclusion formation in response to α-interferon
Brief Report

Adolfo Amici,Monica Emanuelli,Nadia Raffaelli,Silverio Ruggieri,Franca Saccucci,Giulio Magni

View Articletitled, Human erythrocyte pyrimidine 5′-nucleotidase, PN-I, is identical to p36, a protein associated to lupus inclusion formation in response to α-interferon

Viral and cellular cytokines in AIDS-related malignant lymphomatous effusions: Presented in part at the 41st Annual American Society of Hematology Meeting, December 6, 1999, New Orleans, LA.
Brief Report

Yoshiyasu Aoki,Robert Yarchoan,James Braun,Aikichi Iwamoto,Giovanna Tosato

View Articletitled, Viral and cellular cytokines in AIDS-related malignant lymphomatous effusions: Presented in part at the 41st Annual American Society of Hematology Meeting, December 6, 1999, New Orleans, LA.

Severe hereditary spherocytosis and distal renal tubular acidosis associated with the total absence of band 3
Brief Report

Maria Letı́cia Ribeiro,Nicole Alloisio,Helena Almeida,Clara Gomes,Pascale Texier,Carlos Lemos,Gabriela Mimoso,Laurette Morlé,Faı̈za Bey-Cabet,René-Charles Rudigoz,Jean Delaunay,Gabriel Tamagnini

View Articletitled, Severe hereditary spherocytosis and distal renal tubular acidosis associated with the total absence of band 3

Immune response to the ALK oncogenic tyrosine kinase in patients with anaplastic large-cell lymphoma
Brief Report

Karen Pulford,Brunangelo Falini,Alison H. Banham,Diana Codrington,Helen Roberton,Christopher Hatton,David Y. Mason

View Articletitled, Immune response to the ALK oncogenic tyrosine kinase in patients with anaplastic large-cell lymphoma

17

In utero fetal liver hematopoietic stem cell transplantation: is there a role for alloreactive T lymphocytes?

Maria Concetta Renda,Emanuela Fecarotta,Aurelio Maggio,Francesco Dieli,Guido Sireci,Alfredo Salerno,Lola Markling,Magnus Westgren,Gianfranca Damiani,Cristina Jakil,Francesco Picciotto

View Articletitled, In utero fetal liver hematopoietic stem cell transplantation: is there a role for alloreactive T lymphocytes?

CORRESPONDENCE

Proliferative history and hematopoietic function of ex vivo expanded human CD34⁺ cells

Edward F. Srour

View Articletitled, Proliferative history and hematopoietic function of ex vivo expanded human CD34+ cells

Monocytoid B cells

Anne Tierens,Jan Delabie,Chris De Wolf-Peeters

View Articletitled, Monocytoid B cells

Ly-1b cells and Castleman disease

David M. Menke

View Articletitled, Ly-1b cells and Castleman disease

The mouse basophil, a rare and rarely recognized granulocyte

Ann M. Dvorak

View Articletitled, The mouse basophil, a rare and rarely recognized granulocyte

Prognostic correlation of increased angiogenesis in acute myeloid leukemia with cytogenetics

Vijay Reddy,Jan Moreb

View Articletitled, Prognostic correlation of increased angiogenesis in acute myeloid leukemia with cytogenetics

Alopecia and dalteparin: a previously unreported association

Chris Barnes,Danielle Deidun,Kay Hynes,Paul Monagle

View Articletitled, Alopecia and dalteparin: a previously unreported association

Accurate quantification of minimal residual disease at day 15, by real-time quantitative polymerase chain reaction identifies also patients with B-precursor acute lymphoblastic leukemia at high risk for relapse

Valerie de Haas,Willemÿn B. Breunis,Onno J. Verhagen,Henk van den Berg,C. Ellen van der Schoot

View Articletitled, Accurate quantification of minimal residual disease at day 15, by real-time quantitative polymerase chain reaction identifies also patients with B-precursor acute lymphoblastic leukemia at high risk for relapse

Issue Archive

Table of Contents

EDITORIALS

PLENARY PAPERS

PERSPECTIVES

HOW I TREAT

How I treat patients with thrombotic thrombocytopenic purpura–hemolytic uremic syndrome Clinical Trials & Observations

CHEMOKINES

CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS

Nonmyeloablative stem cell transplantation for congenital immunodeficiencies Clinical Trials & Observations

Effect of postremission chemotherapy before human leukocyte antigen–identical sibling transplantation for acute myelogenous leukemia in first complete remission Clinical Trials & Observations

Radioimmunotherapy with iodine 131I tositumomab for relapsed or refractory B-cell non-Hodgkin lymphoma: updated results and long-term follow-up of the University of Michigan experience Clinical Trials & Observations

Soluble stem cell factor receptor (CD117) and IL-2 receptor alpha chain (CD25) levels in the plasma of patients with mastocytosis: relationships to disease severity and bone marrow pathology Clinical Trials & Observations

B7-2–positive myeloma: incidence, clinical characteristics, prognostic significance, and implications for tumor immunotherapy Clinical Trials & Observations

Prognostic factors and treatment outcome in primary progressive Hodgkin lymphoma: a report from the German Hodgkin Lymphoma Study Group Clinical Trials & Observations

A new morphologic classification system for acute promyelocytic leukemia distinguishes cases with underlyingPLZF/RARA gene rearrangements Clinical Trials & Observations

Characterization of acute promyelocytic leukemia cases lacking the classic t(15;17): results of the European Working Party Clinical Trials & Observations

ERRATA

GENE THERAPY

HEMATOPOIESIS

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

Platelet adhesion to collagen in healthy volunteers is influenced by variation of both α2β1 density and von Willebrand factor Clinical Trials & Observations

Combinations of 4 mutations (FV R506Q, FV H1299R, FV Y1702C, PT 20210G/A) affecting the prothrombinase complex in a thrombophilic family Clinical Trials & Observations

IMMUNOBIOLOGY

NEOPLASIA

PHAGOCYTES

RED CELLS

TRANSFUSION MEDICINE

BRIEF REPORTS

Hydroxyurea-induced marked oscillations of platelet counts in patients with polycythemia vera Brief Report

Somatic mosaicism and compound heterozygosity in female hemophilia B Brief Report

Reassessment of interactions between hematopoietic receptors using common beta-chain and interleukin-3–specific receptor beta-chain–null cells: no evidence of functional interactions with receptors for erythropoietin, granulocyte colony-stimulating factor, or stem cell factor Brief Report

Polarized expression of bone morphogenetic protein-4 in the human aorta-gonad-mesonephros region Brief Report

Coagulation and fibrinolytic activities in 2 siblings with β2-glycoprotein I deficiency Brief Report

Human erythrocyte pyrimidine 5′-nucleotidase, PN-I, is identical to p36, a protein associated to lupus inclusion formation in response to α-interferon Brief Report

Viral and cellular cytokines in AIDS-related malignant lymphomatous effusions: Presented in part at the 41st Annual American Society of Hematology Meeting, December 6, 1999, New Orleans, LA. Brief Report

Severe hereditary spherocytosis and distal renal tubular acidosis associated with the total absence of band 3 Brief Report

Immune response to the ALK oncogenic tyrosine kinase in patients with anaplastic large-cell lymphoma Brief Report

17

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ASH Publications

American Society of Hematology

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How I treat patients with thrombotic thrombocytopenic purpura–hemolytic uremic syndrome
Clinical Trials & Observations

Nonmyeloablative stem cell transplantation for congenital immunodeficiencies
Clinical Trials & Observations

Effect of postremission chemotherapy before human leukocyte antigen–identical sibling transplantation for acute myelogenous leukemia in first complete remission
Clinical Trials & Observations

Radioimmunotherapy with iodine ¹³¹I tositumomab for relapsed or refractory B-cell non-Hodgkin lymphoma: updated results and long-term follow-up of the University of Michigan experience
Clinical Trials & Observations

Soluble stem cell factor receptor (CD117) and IL-2 receptor alpha chain (CD25) levels in the plasma of patients with mastocytosis: relationships to disease severity and bone marrow pathology
Clinical Trials & Observations

B7-2–positive myeloma: incidence, clinical characteristics, prognostic significance, and implications for tumor immunotherapy
Clinical Trials & Observations

Prognostic factors and treatment outcome in primary progressive Hodgkin lymphoma: a report from the German Hodgkin Lymphoma Study Group
Clinical Trials & Observations

A new morphologic classification system for acute promyelocytic leukemia distinguishes cases with underlyingPLZF/RARA gene rearrangements
Clinical Trials & Observations

Characterization of acute promyelocytic leukemia cases lacking the classic t(15;17): results of the European Working Party
Clinical Trials & Observations

Platelet adhesion to collagen in healthy volunteers is influenced by variation of both α₂β₁ density and von Willebrand factor
Clinical Trials & Observations

Combinations of 4 mutations (FV R506Q, FV H1299R, FV Y1702C, PT 20210G/A) affecting the prothrombinase complex in a thrombophilic family
Clinical Trials & Observations

Hydroxyurea-induced marked oscillations of platelet counts in patients with polycythemia vera
Brief Report

Somatic mosaicism and compound heterozygosity in female hemophilia B
Brief Report

Reassessment of interactions between hematopoietic receptors using common beta-chain and interleukin-3–specific receptor beta-chain–null cells: no evidence of functional interactions with receptors for erythropoietin, granulocyte colony-stimulating factor, or stem cell factor
Brief Report

Polarized expression of bone morphogenetic protein-4 in the human aorta-gonad-mesonephros region
Brief Report

Coagulation and fibrinolytic activities in 2 siblings with β₂-glycoprotein I deficiency
Brief Report

Human erythrocyte pyrimidine 5′-nucleotidase, PN-I, is identical to p36, a protein associated to lupus inclusion formation in response to α-interferon
Brief Report

Viral and cellular cytokines in AIDS-related malignant lymphomatous effusions: Presented in part at the 41st Annual American Society of Hematology Meeting, December 6, 1999, New Orleans, LA.
Brief Report

Severe hereditary spherocytosis and distal renal tubular acidosis associated with the total absence of band 3
Brief Report

Immune response to the ALK oncogenic tyrosine kinase in patients with anaplastic large-cell lymphoma
Brief Report