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Volume 95, Issue 8

April 15 2000

In this Issue

FOCUS ON HEMATOLOGY
ERRATA
PLENARY PAPERS
REVIEW ARTICLES
CHEMOKINES
CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS
GENE THERAPY
HEMATOPOIESIS
HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY
IMMUNOBIOLOGY
NEOPLASIA
RED CELLS
TRANSFUSION MEDICINE
BRIEF REPORTS
CORRESPONDENCE

FOCUS ON HEMATOLOGY

Introduction: functional polarity of motile neutrophils

C. Wayne Smith

View Articletitled, Introduction: functional polarity of motile neutrophils

Neutrophil polarity and locomotion are associated with surface redistribution of leukosialin (CD43), an antiadhesive membrane molecule

Stéphanie Seveau,Hansuli Keller,Frederick R. Maxfield,Friedrich Piller,Lise Halbwachs-Mecarelli

View Articletitled, Neutrophil polarity and locomotion are associated with surface redistribution of leukosialin (CD43), an antiadhesive membrane molecule

Oriented endocytic recycling of α5β1 in motile neutrophils

Lynda M. Pierini,Moira A. Lawson,Robert J. Eddy,Bill Hendey,Frederick R. Maxfield

View Articletitled, Oriented endocytic recycling of α5β1 in motile neutrophils

Introduction: TH2-inducing DC2 for immunotherapy

Yong-Jun Liu,Bianca Blom

View Articletitled, Introduction: TH2-inducing DC2 for immunotherapy

Granulocyte-colony stimulating factor mobilizes T helper 2-inducing dendritic cells

Mario Arpinati,Cherie L. Green,Shelly Heimfeld,Jill E. Heuser,Claudio Anasetti

View Articletitled, Granulocyte-colony stimulating factor mobilizes T helper 2-inducing dendritic cells

ERRATA

Erratum in Thieblemont et al, “Mucosa-associated lymphoid tissue lymphoma is a disseminated disease in 1/3 of 158 patients analyzed,” Blood, 2000;95:802-806.

View Articletitled, Erratum in Thieblemont et al, “Mucosa-associated lymphoid tissue lymphoma is a disseminated disease in 1/3 of 158 patients analyzed,” Blood, 2000;95:802-806.

PLENARY PAPERS

Structure of the activation domain of the GM-CSF/IL-3/IL-5 receptor common β-chain bound to an antagonist

Jamie Rossjohn,William J. McKinstry,Joanna M. Woodcock,Barbara J. McClure,Timothy R. Hercus,Michael W. Parker,Angel F. Lopez,Christopher J. Bagley

View Articletitled, Structure of the activation domain of the GM-CSF/IL-3/IL-5 receptor common β-chain bound to an antagonist

REVIEW ARTICLES

Development of lentiviral vectors for gene therapy for human diseases

Gary L. Buchschacher, Jr,Flossie Wong-Staal

View Articletitled, Development of lentiviral vectors for gene therapy for human diseases

CHEMOKINES

Stromal cell-derived factor-1α stimulates tyrosine phosphorylation of multiple focal adhesion proteins and induces migration of hematopoietic progenitor cells: roles of phosphoinositide-3 kinase and protein kinase C

Jian-Feng Wang,In-Woo Park,Jerome E. Groopman

View Articletitled, Stromal cell-derived factor-1α stimulates tyrosine phosphorylation of multiple focal adhesion proteins and induces migration of hematopoietic progenitor cells: roles of phosphoinositide-3 kinase and protein kinase C

CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS

Effects of megakaryocyte growth and development factor on platelet production, platelet life span, and platelet function in healthy human volunteers

Laurence A. Harker,Lorin K. Roskos,Ulla M. Marzec,Richard A. Carter,Judith K. Cherry,Birgitta Sundell,Ellen N. Cheung,Dixon Terry,William Sheridan

View Articletitled, Effects of megakaryocyte growth and development factor on platelet production, platelet life span, and platelet function in healthy human volunteers

Acute onset hemoglobinemia and/or hemoglobinuria and sequelae following Rh_o(D) immune globulin intravenous administration in immune thrombocytopenic purpura patients

Ann Reed Gaines

View Articletitled, Acute onset hemoglobinemia and/or hemoglobinuria and sequelae following Rho(D) immune globulin intravenous administration in immune thrombocytopenic purpura patients

A double-blind, placebo-controlled trial of pegylated recombinant human megakaryocyte growth and development factor as an adjunct to induction and consolidation therapy for patients with acute myeloid leukemia

Charles A. Schiffer,Kenneth Miller,Richard A. Larson,Philip C. Amrein,Joseph H. Antin,Valter J. Zani,Richard M. Stone

View Articletitled, A double-blind, placebo-controlled trial of pegylated recombinant human megakaryocyte growth and development factor as an adjunct to induction and consolidation therapy for patients with acute myeloid leukemia

GENE THERAPY

Improved muscle-derived expression of human coagulation factor IX from a skeletal actin/CMV hybrid enhancer/promoter

J. Nathan Hagstrom,Linda B. Couto,Ciaran Scallan,Melissa Burton,Mark L. McCleland,Paul A. Fields,Valder R. Arruda,Roland W. Herzog,Katherine A. High

View Articletitled, Improved muscle-derived expression of human coagulation factor IX from a skeletal actin/CMV hybrid enhancer/promoter

HEMATOPOIESIS

GATA-1 interacts with the myeloid PU.1 transcription factor and represses PU.1-dependent transcription

Claus Nerlov,Erich Querfurth,Holger Kulessa,Thomas Graf

View Articletitled, GATA-1 interacts with the myeloid PU.1 transcription factor and represses PU.1-dependent transcription

Granulocyte-macrophage colony-stimulating factor stimulation results in phosphorylation of cAMP response element-binding protein through activation of pp90RSK

Evelyn M. Kwon,Maribeth A. Raines,John Blenis,Kathleen M. Sakamoto

View Articletitled, Granulocyte-macrophage colony-stimulating factor stimulation results in phosphorylation of cAMP response element-binding protein through activation of pp90RSK

Identification and characterization of a bipotent (erythroid and megakaryocytic) cell precursor from the spleen of phenylhydrazine-treated mice

Alessandro Maria Vannucchi,Francesco Paoletti,Silvia Linari,Cristina Cellai,Roberto Caporale,Pierluigi Rossi Ferrini,Massimo Sanchez,Giovanni Migliaccio,Anna Rita Migliaccio

View Articletitled, Identification and characterization of a bipotent (erythroid and megakaryocytic) cell precursor from the spleen of phenylhydrazine-treated mice

Cloning of PRV-1, a novel member of the uPAR receptor superfamily, which is overexpressed in polycythemia rubra vera

Snežana Temerinac,Steffen Klippel,Elisabeth Strunck,Sabine Röder,Michael Lübbert,Winand Lange,Marc Azemar,Gerold Meinhardt,Hans-Eckart Schaefer,Heike L. Pahl

View Articletitled, Cloning of PRV-1, a novel member of the uPAR receptor superfamily, which is overexpressed in polycythemia rubra vera

Induction of apoptosis by extracellular ubiquitin in human hematopoietic cells: possible involvement of STAT3 degradation by proteasome pathway in interleukin 6-dependent hematopoietic cells

Hanako Daino,Itaru Matsumura,Koji Takada,Junko Odajima,Hirokazu Tanaka,Shuji Ueda,Hirohiko Shibayama,Hirokazu Ikeda,Masahiko Hibi,Takashi Machii,Toshio Hirano,Yuzuru Kanakura

View Articletitled, Induction of apoptosis by extracellular ubiquitin in human hematopoietic cells: possible involvement of STAT3 degradation by proteasome pathway in interleukin 6-dependent hematopoietic cells

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

Factor XIIIa supports microvascular endothelial cell adhesion and inhibits capillary tube formation in fibrin

Susan M. Dallabrida,Lisa A. Falls,David H. Farrell

View Articletitled, Factor XIIIa supports microvascular endothelial cell adhesion and inhibits capillary tube formation in fibrin

Transcriptional control of the human plasma membranephospholipid scramblase 1 gene is mediated by interferon-α

Quansheng Zhou,Ji Zhao,Fahad Al-Zoghaibi,Aimin Zhou,Therese Wiedmer,Robert H. Silverman,Peter J. Sims

View Articletitled, Transcriptional control of the human plasma membranephospholipid scramblase 1 gene is mediated by interferon-α

Cloning of the human platelet F11 receptor: a cell adhesion molecule member of the immunoglobulin superfamily involved in platelet aggregation: Presented in part at the XVIIth Congress of the International Society on Thrombosis and Haemostasis, Washington, DC, August 14-21, 1999.

Malgorzata B. Sobocka,Tomasz Sobocki,Probal Banerjee,Cipora Weiss,Julie I. Rushbrook,Allen J. Norin,John Hartwig,Moro O. Salifu,Mariana S. Markell,Anna Babinska,Yigal H. Ehrlich,Elizabeth Kornecki

View Articletitled, Cloning of the human platelet F11 receptor: a cell adhesion molecule member of the immunoglobulin superfamily involved in platelet aggregation: Presented in part at the XVIIth Congress of the International Society on Thrombosis and Haemostasis, Washington, DC, August 14-21, 1999.

IMMUNOBIOLOGY

Functional comparison of thymic B cells and dendritic cells in vivo

Petra Kleindienst,Isabelle Chretien,Thomas Winkler,Thomas Brocker

View Articletitled, Functional comparison of thymic B cells and dendritic cells in vivo

Tracing uptake of C3dg-conjugated antigen into B cells via complement receptor type 2 (CR2, CD21)

Michael W. Hess,Michael G. Schwendinger,Eeva-Liisa Eskelinen,Kristian Pfaller,Margit Pavelka,Manfred P. Dierich,Wolfgang M. Prodinger

View Articletitled, Tracing uptake of C3dg-conjugated antigen into B cells via complement receptor type 2 (CR2, CD21)

Sphingosine-1-phosphate is a ligand for the G protein-coupled receptor EDG-6

James R. Van Brocklyn,Markus H. Gräler,Günter Bernhardt,John P. Hobson,Martin Lipp,Sarah Spiegel

View Articletitled, Sphingosine-1-phosphate is a ligand for the G protein-coupled receptor EDG-6

NEOPLASIA

Vascular endothelial growth factor and interleukin-6 in paracrine tumor-stromal cell interactions in multiple myeloma

Berno Dankbar,Teresa Padró,Regine Leo,Birgit Feldmann,Martin Kropff,Rolf M. Mesters,Hubert Serve,Wolfgang E. Berdel,Joachim Kienast

View Articletitled, Vascular endothelial growth factor and interleukin-6 in paracrine tumor-stromal cell interactions in multiple myeloma

Increased angiogenesis in the bone marrow of patients with acute myeloid leukemia

Teresa Padró,Sandra Ruiz,Ralf Bieker,Horst Bürger,Martin Steins,Joachim Kienast,Thomas Büchner,Wolfgang E. Berdel,Rolf M. Mesters

View Articletitled, Increased angiogenesis in the bone marrow of patients with acute myeloid leukemia

Abundance of cyclin B1 regulates γ-radiation–induced apoptosis

Lisa A. Porter,Gurmit Singh,Jonathan M. Lee

View Articletitled, Abundance of cyclin B1 regulates γ-radiation–induced apoptosis

Immunoglobulin heavy-chain consensus probes for real-time PCR quantification of residual disease in acute lymphoblastic leukemia

John W. Donovan,Marco Ladetto,Guangyong Zou,Donna Neuberg,Christina Poor,Dorothy Bowers,John G. Gribben

View Articletitled, Immunoglobulin heavy-chain consensus probes for real-time PCR quantification of residual disease in acute lymphoblastic leukemia

Molecular analysis of lineage-specific chimerism and minimal residual disease by RT-PCR of p210^BCR-ABL and p190^BCR-ABL after allogeneic bone marrow transplantation for chronic myeloid leukemia: increasing mixed myeloid chimerism and p190^BCR-ABL detection precede cytogenetic relapse

Josefina Serrano,Jose Roman,Joaquin Sanchez,Antonio Jimenez,Juan A. Castillejo,Concepcion Herrera,Maria Gracia Gonzalez,Luisa Reina,Maria del Carmen Rodriguez,Miguel A. Alvarez,Juan Maldonado,Antonio Torres

View Articletitled, Molecular analysis of lineage-specific chimerism and minimal residual disease by RT-PCR of p210BCR-ABL and p190BCR-ABL after allogeneic bone marrow transplantation for chronic myeloid leukemia: increasing mixed myeloid chimerism and p190BCR-ABL detection precede cytogenetic relapse

MUC1 is activated in a B-cell lymphoma by the t(1;14)(q21;q32) translocation and is rearranged and amplified in B-cell lymphoma subsets

Vadim G. Dyomin,Nallasivam Palanisamy,Kenneth O. Lloyd,Katerina Dyomina,Suresh C. Jhanwar,Jane Houldsworth,R. S. K. Chaganti

View Articletitled, MUC1 is activated in a B-cell lymphoma by the t(1;14)(q21;q32) translocation and is rearranged and amplified in B-cell lymphoma subsets

Isolation and characterization of an acute promyelocytic leukemia cell line selectively resistant to the novel antileukemic and apoptogenic retinoid 6-[3-adamantyl-4-hydroxyphenyl]-2-naphthalene carboxylic acid

Isabella Ponzanelli,Maurizio Giannı̀,Raffaella Giavazzi,Angela Garofalo,Ines Nicoletti,Uwe Reichert,Eugenio Erba,Alessandro Rambaldi,Mineko Terao,Enrico Garattini

View Articletitled, Isolation and characterization of an acute promyelocytic leukemia cell line selectively resistant to the novel antileukemic and apoptogenic retinoid 6-[3-adamantyl-4-hydroxyphenyl]-2-naphthalene carboxylic acid

The t(5;17) acute promyelocytic leukemia fusion protein NPM-RAR interacts with co-repressor and co-activator proteins and exhibits both positive and negative transcriptional properties

Robert L. Redner,J. Don Chen,Elizabeth A. Rush,Hui Li,Sheri L. Pollock

View Articletitled, The t(5;17) acute promyelocytic leukemia fusion protein NPM-RAR interacts with co-repressor and co-activator proteins and exhibits both positive and negative transcriptional properties

Concurrent activation of a novel putative transforming gene,myeov, and cyclin D1 in a subset of multiple myeloma cell lines with t(11;14)(q13;q32)

Johannes W. G. Janssen,Jan-Willem Vaandrager,Tanja Heuser,Anna Jauch,Philip M. Kluin,Erik Geelen,P. Leif Bergsagel,W. Michael Kuehl,Hans G. Drexler,Takemi Otsuki,Claus R. Bartram,Ed Schuuring

View Articletitled, Concurrent activation of a novel putative transforming gene,myeov, and cyclin D1 in a subset of multiple myeloma cell lines with t(11;14)(q13;q32)

RED CELLS

Weak D alleles express distinct phenotypes

Franz F. Wagner,Alexander Frohmajer,Birgit Ladewig,Nicole I. Eicher,Cornelie B. Lonicer,Thomas H. Müller,Manfred H. Siegel,Willy A. Flegel

View Articletitled, Weak D alleles express distinct phenotypes

TRANSFUSION MEDICINE

Survival of donor cells 25 years after intrauterine transfusion

Henk E. Viëtor,Eric Hallensleben,Simone P. M. J. van Bree,Ellen M. W. van der Meer,Suzanne E. J. Kaal,Jack Bennebroek-Gravenhorst,Humphrey H. H. Kanhai,Anneke Brand,Frans H. J. Claas

View Articletitled, Survival of donor cells 25 years after intrauterine transfusion

BRIEF REPORTS

Constitutive activation of LIL-Stat in adult T-cell leukemia cells
Brief Report

Junichi Tsukada,Yoko Toda,Masahiro Misago,Yoshiya Tanaka,Philip E. Auron,Sumiya Eto

View Articletitled, Constitutive activation of LIL-Stat in adult T-cell leukemia cells

The Ikaros gene, a central regulator of lymphoid differentiation, fuses to the BCL6 gene as a result of t(3;7)(q27;p12) translocation in a patient with diffuse large B-cell lymphoma
Brief Report

Yoshitaka Hosokawa,Yumiko Maeda,Ryo Ichinohasama,Ikuo Miura,Masafumi Taniwaki,Masao Seto

View Articletitled, The Ikaros gene, a central regulator of lymphoid differentiation, fuses to the BCL6 gene as a result of t(3;7)(q27;p12) translocation in a patient with diffuse large B-cell lymphoma

Presence of clone-specific antigen receptor gene rearrangements at birth indicates an in utero origin of diverse types of early childhood acute lymphoblastic leukemia
Brief Report

Karin Fasching,Simon Panzer,Oskar A. Haas,Rolf Marschalek,Helmut Gadner,E. Renate Panzer-Grümayer

View Articletitled, Presence of clone-specific antigen receptor gene rearrangements at birth indicates an in utero origin of diverse types of early childhood acute lymphoblastic leukemia

Expression of Ig-β (CD79b) by chronic lymphocytic leukemia B cells that lack immunoglobulin heavy-chain allelic exclusion
Brief Report

Laura Z. Rassenti,Thomas J. Kipps

View Articletitled, Expression of Ig-β (CD79b) by chronic lymphocytic leukemia B cells that lack immunoglobulin heavy-chain allelic exclusion

CORRESPONDENCE

Nucleotide insertions and deletions within the homopolymeric runs of adenines and thymidines of BCL10 cDNAs in normal peripheral blood leukocytes

Hidenobu Takahashi,Yumiko Maeda,Masao Seto,Yoshitaka Hosokawa

View Articletitled, Nucleotide insertions and deletions within the homopolymeric runs of adenines and thymidines of BCL10 cDNAs in normal peripheral blood leukocytes

Treatment outcome in infant acute lymphoblastic leukemia

Alina Ferster,Yves Benoit,Nadine Francotte,Marie-Françoise Dresse,Anne Uyttebroeck,Emmanuel Plouvier,Antoine Thyss,Patrick Lutz,Geneviève Marguerite,Catherine Behar,Françoise Mazingue,Patrick Boutard,Frederic Millot,Xavier Rialland,Françoise Mechinaud,Lucilia Norton,Alain Robert,Jacques Otten,Etienne Vilmer,Noel Philippe,Christine Waterkeyn,Stefan Suciu

View Articletitled, Treatment outcome in infant acute lymphoblastic leukemia

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Issue Archive

Table of Contents

FOCUS ON HEMATOLOGY

ERRATA

PLENARY PAPERS

REVIEW ARTICLES

CHEMOKINES

CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS

GENE THERAPY

HEMATOPOIESIS

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

IMMUNOBIOLOGY

NEOPLASIA

RED CELLS

TRANSFUSION MEDICINE

BRIEF REPORTS

Constitutive activation of LIL-Stat in adult T-cell leukemia cells Brief Report

The Ikaros gene, a central regulator of lymphoid differentiation, fuses to the BCL6 gene as a result of t(3;7)(q27;p12) translocation in a patient with diffuse large B-cell lymphoma Brief Report

Presence of clone-specific antigen receptor gene rearrangements at birth indicates an in utero origin of diverse types of early childhood acute lymphoblastic leukemia Brief Report

Expression of Ig-β (CD79b) by chronic lymphocytic leukemia B cells that lack immunoglobulin heavy-chain allelic exclusion Brief Report

CORRESPONDENCE

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ASH Publications

American Society of Hematology

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Constitutive activation of LIL-Stat in adult T-cell leukemia cells
Brief Report

The Ikaros gene, a central regulator of lymphoid differentiation, fuses to the BCL6 gene as a result of t(3;7)(q27;p12) translocation in a patient with diffuse large B-cell lymphoma
Brief Report

Presence of clone-specific antigen receptor gene rearrangements at birth indicates an in utero origin of diverse types of early childhood acute lymphoblastic leukemia
Brief Report

Expression of Ig-β (CD79b) by chronic lymphocytic leukemia B cells that lack immunoglobulin heavy-chain allelic exclusion
Brief Report