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Issue Archive

Volume 94, Issue 8
October 15 1999
Blood Cover Image for Volume 94, Issue 8

Table of Contents

INTRODUCTION: FOCUS ON HEMATOLOGY

CD34+ or CD34−: Does it Really Matter?
Margaret A. Goodell
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FOCUS ON HEMATOLOGY

Reversible Expression of CD34 by Murine Hematopoietic Stem Cells
Takashi Sato,Joseph H. Laver,Makio Ogawa
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PLENARY PAPERS

Posttranslational Processing of the Thrombopoietin Receptor Is Impaired in Polycythemia Vera
Alison R. Moliterno,Jerry L. Spivak
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A Bispecific Diabody That Mediates Natural Killer Cell Cytotoxicity Against Xenotransplantated Human Hodgkin’s Tumors
Michaela A.E. Arndt,Jürgen Krauss,Sergey M. Kipriyanov,Michael Pfreundschuh,Melvyn Little
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PERSPECTIVE

Uremic Bleeding: Closing the Circle After 30 Years of Controversies?
Marina Noris,Giuseppe Remuzzi
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CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS

Lymphoproliferative Syndrome With Autoimmunity: A Possible Genetic Basis for Dominant Expression of the Clinical Manifestations
Frédéric Rieux-Laucat,Séverine Blachère,Sylvia Danielan,Jean Pierre De Villartay,Mathias Oleastro,Eric Solary,Brigitte Bader-Meunier,Peter Arkwright,Corinne Pondaré,Françoise Bernaudin,Helen Chapel,Susan Nielsen,Mohamed Berrah,Alain Fischer,Françoise Le Deist
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Monosomy 13 Is Associated With the Transition of Monoclonal Gammopathy of Undetermined Significance to Multiple Myeloma
Hervé Avet-Loiseau,Jian-Yong Li,Nadine Morineau,Thierry Facon,Christophe Brigaudeau,Jean-Luc Harousseau,Bernard Grosbois,Régis Bataille,on behalf of the Intergroupe Francophone du Myélome
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Gene-Gene and Gene-Environment Interactions Determine Risk of Thrombosis in Families With Inherited Antithrombin Deficiency
H.H. van Boven,J.P. Vandenbroucke,E. Briët,F.R. Rosendaal
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HEMATOPOIESIS

Symmetry of Initial Cell Divisions Among Primitive Hematopoietic Progenitors Is Independent of Ontogenic Age and Regulatory Molecules
Shiang Huang,Ping Law,Karl Francis,Bernhard O. Palsson,Anthony D. Ho
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Enhanced In Vivo Regenerative Potential of HOXB4-Transduced Hematopoietic Stem Cells With Regulation of Their Pool Size
Unnur Thorsteinsdottir,Guy Sauvageau,R. Keith Humphries
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Increased Fetal and Extramedullary Hematopoiesis in Fas-Deficient C57BL/6-lpr/lpr Mice
Elke Schneider,Géraldine Moreau,Anne Arnould,Florence Vasseur,Naushad Khodabaccus,Michel Dy,Sophie Ezine
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Gene Duplication of Zebrafish JAK2 Homologs Is Accompanied by Divergent Embryonic Expression Patterns: Only jak2a Is Expressed During Erythropoiesis
Andrew C. Oates,Alison Brownlie,Stephen J. Pratt,Danielle V. Irvine,Eric C. Liao,Barry H. Paw,Kristen J. Dorian,Stephen L. Johnson,John H. Postlethwait,Leonard I. Zon,Andrew F. Wilks
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Genetic Modification of Human B-Cell Development: B-Cell Development Is Inhibited by the Dominant Negative Helix Loop Helix Factor Id3
Ana C. Jaleco,Alexander P.A. Stegmann,Mirjam H.M. Heemskerk,Franka Couwenberg,Arjen Q. Bakker,Kees Weijer,Hergen Spits
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Expression of pT mRNA in a Committed Dendritic Cell Precursor in the Human Thymus
Pieter C.M. Res,Franka Couwenberg,Florry A. Vyth-Dreese,Hergen Spits
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The Wsh, W57, and Ph Kit Expression Mutations Define Tissue-Specific Control Elements Located Between −23 and −154 kb Upstream of Kit
Georgina Berrozpe,Inna Timokhina,Steven Yukl,Youichi Tajima,Masao Ono,Andrew D. Zelenetz,Peter Besmer
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Activation of the Erythropoietin Receptor Is Not Required for Internalization of Bound Erythropoietin
Diana L. Beckman,Lilie L. Lin,Mary E. Quinones,Gregory D. Longmore
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A Thrombopoietin Receptor Mutant Deficient in Jak-STAT Activation Mediates Proliferation But Not Differentiation in UT-7 Cells
Marion Dorsch,Nika N. Danial,Paul B. Rothman,Stephen P. Goff
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Unique Differentiation Programs of Human Fetal Liver Stem Cells Shown Both In Vitro and In Vivo in NOD/SCID Mice
Franck E. Nicolini,Tessa L. Holyoake,Johanne D. Cashman,Pat P.Y. Chu,Karen Lambie,Connie J. Eaves
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HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

Targeting of a Heterologous Protein to a Regulated Secretion Pathway in Cultured Endothelial Cells
Yvonne H. Datta,Hagop Youssoufian,Peter W. Marks,Bruce M. Ewenstein
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Influence of Fibrillar Collagen Structure on the Mechanisms of Platelet Thrombus Formation Under Flow
Brian Savage,Mark H. Ginsberg,Zaverio M. Ruggeri
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Neutrophil Adhesion on Polyurethanes Preadsorbed With High Molecular Weight Kininogen
Lin-Yue L. Yung,Robert W. Colman,Stuart L. Cooper
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Circulating Activated Platelets Assist THP-1 Monocytoid/Endothelial Cell Interaction Under Shear Stress
Gregor Theilmeier,Tim Lenaerts,Claude Remacle,Désiré Collen,Jos Vermylen,Marc F. Hoylaerts
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A Novel Approach to Arterial Thrombolysis
Petr Klement,Peng Liao,Laszlo Bajzar
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IMMUNOBIOLOGY

β2-Microglobulin Identified as an Apoptosis-Inducing Factor and Its Characterization
Masaki Mori,Yasuhito Terui,Masayuki Ikeda,Hiroshi Tomizuka,Masaya Uwai,Tadashi Kasahara,Nobuyuki Kubota,Takehito Itoh,Yuji Mishima,Miyuki Douzono-Tanaka,Muneo Yamada,Seiichi Shimamura,Jiro Kikuchi,Yusuke Furukawa,Yukihito Ishizaka,Kazuma Ikeda,Hiroyuki Mano,Keiya Ozawa,Kiyohiko Hatake
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Fibronectin Upregulates Gelatinase B (MMP-9) and Induces Coordinated Expression of Gelatinase A (MMP-2) and Its Activator MT1-MMP (MMP-14) by Human T Lymphocyte Cell Lines. A Process Repressed Through RAS/MAP Kinase Signaling Pathways
Jordi Esparza,Carme Vilardell,Javier Calvo,Manel Juan,Jordi Vives,Alvaro Urbano-Márquez,Jordi Yagüe,Maria C. Cid
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Signaling Through CD43 Induces Natural Killer Cell Activation, Chemokine Release, and PYK-2 Activation
Marta Nieto,José Luis Rodrı́guez-Fernández,Francisco Navarro,David Sancho,José M.R. Frade,Mario Mellado,Carlos Martı́nez-A,Carlos Cabañas,Francisco Sánchez-Madrid
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An Inositolphosphate-Binding Immunophilin, IPBP12
Earlene Brown Cunningham
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Analysis of T Cells in Paroxysmal Nocturnal Hemoglobinuria Provides Direct Evidence That Thymic T-Cell Production Declines With Age
Stephen J. Richards,Gareth J. Morgan,Peter Hillmen
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Monocytoid B Cells Are Distinct From Splenic Marginal Zone Cells and Commonly Derive From Unmutated Naive B Cells and Less Frequently From Postgerminal Center B Cells by Polyclonal Transformation
Karoline Stein,Michael Hummel,Petra Korbjuhn,Hans-Dieter Foss,Ioannis Anagnostopoulos,Theresa Marafioti,Harald Stein
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Human Immunodeficiency Virus nef Gene Expression Affects Generation and Function of Human T Cells, But Not Dendritic Cells
Bruno Verhasselt,Evelien Naessens,Chris Verhofstede,Magda De Smedt,Sigrid Schollen,Tessa Kerre,Dominique Vanhecke,Jean Plum
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Early Maturation of T-Cell Progenitors in the Absence of Glucocorticoids
Rosa Sacedón,Angeles Vicente,Alberto Varas,Eva Jiménez,Juan José Muñoz,Agustı́n G. Zapata
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Resting and Cytokine-Stimulated Human Small Airway Epithelial Cells Recognize and Engulf Apoptotic Eosinophils
Garry M. Walsh,Darren W. Sexton,Morgan G. Blaylock,Catherine M. Convery
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NEOPLASIA

In Vitro Evaluation of Fludarabine in Combination With Cyclophosphamide and/or Mitoxantrone in B-Cell Chronic Lymphocytic Leukemia
Beatriz Bellosillo,Neus Villamor,Dolors Colomer,Gabriel Pons,Emili Montserrat,Joan Gil
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Phenylarsine Oxide Blocks Interleukin-1β–Induced Activation of the Nuclear Transcription Factor NF-κB, Inhibits Proliferation, and Induces Apoptosis of Acute Myelogenous Leukemia Cells
Zeev Estrov,Sunil K. Manna,David Harris,Quin Van,Elihu H. Estey,Hagop M. Kantarjian,Moshe Talpaz,Bharat B. Aggarwal
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A Deletion in the Gene for Transforming Growth Factor β Type I Receptor Abolishes Growth Regulation by Transforming Growth Factor β in a Cutaneous T-Cell Lymphoma
William P. Schiemann,Walther M. Pfeifer,Edi Levi,Marshall E. Kadin,Harvey F. Lodish
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Expression of Human Inducible Nitric Oxide Synthase Gene in T-Cell Lines Infected With Human T-Cell Leukemia Virus Type-I and Primary Adult T-Cell Leukemia Cells
Naoki Mori,Youichi Nunokawa,Yasuaki Yamada,Shuichi Ikeda,Masao Tomonaga,Naoki Yamamoto
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Involvement of Interleukin-10 (IL-10) and Viral IL-6 in the Spontaneous Growth of Kaposi’s Sarcoma Herpesvirus-Associated Infected Primary Effusion Lymphoma Cells
Karen D. Jones,Yoshiyasu Aoki,Yuan Chang,Patrick S. Moore,Robert Yarchoan,Giovanna Tosato
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PHAGOCYTES

Interleukin-10 (IL-10) Selectively Enhances CIS3/SOCS3 mRNA Expression in Human Neutrophils: Evidence for an IL-10–Induced Pathway That Is Independent of STAT Protein Activation
Marco A. Cassatella,Sara Gasperini,Chiara Bovolenta,Federica Calzetti,Marieke Vollebregt,Patrizia Scapini,Martina Marchi,Ritsu Suzuki,Asuka Suzuki,Akihiko Yoshimura
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RED CELLS

The Molecular Basis of a Case of γ-Glutamylcysteine Synthetase Deficiency
Ernest Beutler,Terri Gelbart,Takahito Kondo,Alison T. Matsunaga
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TRANSPLANTATION

ABO Blood Group Antigens on Human Plasma von Willebrand Factor After ABO-Mismatched Bone Marrow Transplantation
Taei Matsui,Taketo Shimoyama,Masanori Matsumoto,Yoshihiro Fujimura,Yoshinobu Takemoto,Masahiro Sako,Jiharu Hamako,Koiti Titani
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Shiga-Like Toxin-1 Receptor on Human Breast Cancer, Lymphoma, and Myeloma and Absence From CD34+ Hematopoietic Stem Cells: Implications for Ex Vivo Tumor Purging and Autologous Stem Cell Transplantation
E.C. LaCasse,M.R. Bray,B. Patterson,W.-M. Lim,S. Perampalam,L. G. Radvanyi,A. Keating,A.K. Stewart,R. Buckstein,J.S. Sandhu,N. Miller,D. Banerjee,D. Singh,A.R. Belch,L.M. Pilarski,J. Gariépy
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Correlation Between Disparity for the Minor Histocompatibility Antigen HA-1 and the Development of Acute Graft-Versus-Host Disease After Allogeneic Marrow Transplantation
Li-Hui Tseng,Ming-Tseh Lin,John A. Hansen,Ted Gooley,Ji Pei,Anajane G. Smith,Emily G. Martin,Effie W. Petersdorf,Paul J. Martin
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Viral Hyperinfection of the Central Nervous System and High Mortality After Hematopoietic Stem Cell Transplantation for Treatment of Theiler’s Murine Encephalomyelitis Virus-Induced Demyelinating Disease
Richard K. Burt,Josette Padilla,Mauro C. Dal Canto,Stephen D. Miller
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Long-Term Chimerism and B-Cell Function After Bone Marrow Transplantation in Patients With Severe Combined Immunodeficiency With B Cells: A Single-Center Study of 22 Patients
Elie Haddad,Françoise Le Deist,Pierre Aucouturier,Marina Cavazzana-Calvo,Stephane Blanche,Geneviève De Saint Basile,Alain Fischer
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BRIEF REPORTS

Expression of Cell-Homologous Genes of Human Herpesvirus-8 in Human Immunodeficiency Virus-Negative Lymphoproliferative Diseases
Mario Luppi,Patrizia Barozzi,Antonio Maiorana,Raffaella Trovato,Roberto Marasca,Monica Morselli,Katia Cagossi,Giuseppe Torelli
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