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Volume 94, Issue 10

November 15 1999

In this Issue

REVIEW ARTICLES
CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS
GENE THERAPY
PHOTOGRAPH
HEMATOPOIESIS
HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY
IMMUNOBIOLOGY
NEOPLASIA
RED CELLS
BRIEF REPORTS
CORRESPONDENCE

REVIEW ARTICLES

Of Man and Mouse: Leukocyte and Endothelial Adhesion Molecule Deficiencies

Amos Etzioni,Claire M. Doerschuk,John M. Harlan

View Articletitled, Of Man and Mouse: Leukocyte and Endothelial Adhesion Molecule Deficiencies

CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS

Treatment and Clinical Management of Primary Mediastinal Large B-Cell Lymphoma With Sclerosis: MACOP-B Regimen and Mediastinal Radiotherapy Monitored by ⁶⁷Gallium Scan in 50 Patients

Pier Luigi Zinzani,Maurizio Martelli,Massimo Magagnoli,Edoardo Pescarmona,Laura Scaramucci,Francesca Palombi,Maurizio Bendandi,Maria Paola Martelli,Stefano Ascani,Giulio Fraternali Orcioni,Stefano A. Pileri,Franco Mandelli,Sante Tura

View Articletitled, Treatment and Clinical Management of Primary Mediastinal Large B-Cell Lymphoma With Sclerosis: MACOP-B Regimen and Mediastinal Radiotherapy Monitored by 67Gallium Scan in 50 Patients

Improved Treatment Results in Childhood B-Cell Neoplasms With Tailored Intensification of Therapy: A Report of the Berlin-Frankfurt-Münster Group Trial NHL-BFM 90

Alfred Reiter,Martin Schrappe,Markus Tiemann,Wolf-Dieter Ludwig,Elif Yakisan,Martin Zimmermann,Georg Mann,Andreas Chott,Wolfram Ebell,Thomas Klingebiel,Norbert Graf,Bernhard Kremens,Stefan Müller-Weihrich,Hans-Jürgen Plüss,Felix Zintl,Günter Henze,Hansjörg Riehm

View Articletitled, Improved Treatment Results in Childhood B-Cell Neoplasms With Tailored Intensification of Therapy: A Report of the Berlin-Frankfurt-Münster Group Trial NHL-BFM 90

A Phase II Trial of 200% ProMACE-CytaBOM in Patients With Previously Untreated Aggressive Lymphomas: Analysis of Response, Toxicity, and Dose Intensity

Leo I. Gordon,Mary Young,Edie Weller,Thomas M. Habermann,Jane N. Winter,John Glick,Chirantan Ghosh,Patrick Flynn,Peter A. Cassileth

View Articletitled, A Phase II Trial of 200% ProMACE-CytaBOM in Patients With Previously Untreated Aggressive Lymphomas: Analysis of Response, Toxicity, and Dose Intensity

Studies on Treatment of Acute Promyelocytic Leukemia With Arsenic Trioxide: Remission Induction, Follow-Up, and Molecular Monitoring in 11 Newly Diagnosed and 47 Relapsed Acute Promyelocytic Leukemia Patients

Chao Niu,Hua Yan,Ting Yu,Hui-Ping Sun,Jian-Xiang Liu,Xiu-Song Li,Wen Wu,Fen-Qin Zhang,Yu Chen,Li Zhou,Jun-Min Li,Xiao-Ying Zeng,Ren-Rong Ou Yang,Mi-Man Yuan,Mei-Yu Ren,Feng-Ying Gu,Qi Cao,Bo-Wei Gu,Xin-Ying Su,Guo-Qiang Chen,Shu-Min Xiong,Ting-dong Zhang,Samuel Waxman,Zhen-Yi Wang,Zhu Chen,Jiong Hu,Zhi-Xiang Shen,Sai-Juan Chen

View Articletitled, Studies on Treatment of Acute Promyelocytic Leukemia With Arsenic Trioxide: Remission Induction, Follow-Up, and Molecular Monitoring in 11 Newly Diagnosed and 47 Relapsed Acute Promyelocytic Leukemia Patients

Long-Term Follow-Up of Autologous Bone Marrow Transplantation in Patients With Relapsed Follicular Lymphoma

Arnold S. Freedman,Donna Neuberg,Peter Mauch,Robert J. Soiffer,Kenneth C. Anderson,David C. Fisher,Robert Schlossman,Edwin P. Alyea,Tak Takvorian,Haddy Jallow,Caroline Kuhlman,Jerome Ritz,Lee M. Nadler,John G. Gribben

View Articletitled, Long-Term Follow-Up of Autologous Bone Marrow Transplantation in Patients With Relapsed Follicular Lymphoma

A High Pretreatment Serum Basic Fibroblast Growth Factor Concentration Is an Independent Predictor of Poor Prognosis in Non-Hodgkin’s Lymphoma

Petri Salven,Lasse Teerenhovi,Heikki Joensuu

View Articletitled, A High Pretreatment Serum Basic Fibroblast Growth Factor Concentration Is an Independent Predictor of Poor Prognosis in Non-Hodgkin’s Lymphoma

Responses in Refractory Hairy Cell Leukemia to a Recombinant Immunotoxin

Robert J. Kreitman,Wyndham H. Wilson,David Robbins,Inger Margulies,Maryalice Stetler-Stevenson,Thomas A. Waldmann,Ira Pastan

View Articletitled, Responses in Refractory Hairy Cell Leukemia to a Recombinant Immunotoxin

GENE THERAPY

Improved Expression in Hematopoietic and Lymphoid Cells in Mice After Transplantation of Bone Marrow Transduced With a Modified Retroviral Vector

Stephanie Halene,Lijun Wang,Robert M. Cooper,David C. Bockstoce,Paul B. Robbins,Donald B. Kohn

View Articletitled, Improved Expression in Hematopoietic and Lymphoid Cells in Mice After Transplantation of Bone Marrow Transduced With a Modified Retroviral Vector

Correction of X-Linked Immunodeficient Mice by Competitive Reconstitution With Limiting Numbers of Normal Bone Marrow Cells

Jurg Rohrer,Mary Ellen Conley

View Articletitled, Correction of X-Linked Immunodeficient Mice by Competitive Reconstitution With Limiting Numbers of Normal Bone Marrow Cells

PHOTOGRAPH

Photograph

View Articletitled, Photograph

HEMATOPOIESIS

Functional Characterization of the Human Platelet Glycoprotein V Gene Promoter: A Specific Marker of Late Megakaryocytic Differentiation

Adeline Lepage,Georges Uzan,Nadège Touche,Martine Morales,Jean-Pierre Cazenave,François Lanza,Corinne de la Salle

View Articletitled, Functional Characterization of the Human Platelet Glycoprotein V Gene Promoter: A Specific Marker of Late Megakaryocytic Differentiation

A Minimal Cytoplasmic Subdomain of the Erythropoietin Receptor Mediates Erythroid and Megakaryocytic Cell Development

Chris P. Miller,Zi Y. Liu,Constance T. Noguchi,Don M. Wojchowski

View Articletitled, A Minimal Cytoplasmic Subdomain of the Erythropoietin Receptor Mediates Erythroid and Megakaryocytic Cell Development

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

Tissue Factor and Factor VIIa Receptor/Ligand Interactions Induce Proinflammatory Effects in Macrophages

Malcolm A. Cunningham,Pauline Romas,Paul Hutchinson,Stephen R. Holdsworth,Peter G. Tipping

View Articletitled, Tissue Factor and Factor VIIa Receptor/Ligand Interactions Induce Proinflammatory Effects in Macrophages

Lupus Anticoagulants Form Immune Complexes With Prothrombin and Phospholipid That Can Augment Thrombin Production in Flow

Susan L. Field,Philip J. Hogg,Elise B. Daly,Yan-Ping Dai,Barbara Murray,Daniel Owens,Colin N. Chesterman

View Articletitled, Lupus Anticoagulants Form Immune Complexes With Prothrombin and Phospholipid That Can Augment Thrombin Production in Flow

IMMUNOBIOLOGY

Coexistence of Two Functioning T-Cell Repertoires in Healthy Ex-Thalassemics Bearing a Persistent Mixed Chimerism Years After Bone Marrow Transplantation

Manuela Battaglia,Marco Andreani,Marisa Manna,Sonia Nesci,Paola Tonucci,Barbara Persini,Gioacchino Robustelli della Cuna,Arcangelo Nocera,Jack Gorski,Guido Lucarelli,Raffaele De Palma

View Articletitled, Coexistence of Two Functioning T-Cell Repertoires in Healthy Ex-Thalassemics Bearing a Persistent Mixed Chimerism Years After Bone Marrow Transplantation

Epstein-Barr Virus Induces Fas (CD95) in T Cells and Fas Ligand in B Cells Leading to T-Cell Apoptosis

Jerome E. Tanner,Caroline Alfieri

View Articletitled, Epstein-Barr Virus Induces Fas (CD95) in T Cells and Fas Ligand in B Cells Leading to T-Cell Apoptosis

Enhanced Liver Uptake of Opsonized Red Blood Cells After In Vivo Transfer of FcγRIIA cDNA to the Liver

Petr Bezdicek,Stefan Worgall,Imre Kovesdi,Moo-Kyung Kim,Jong-Gu Park,Theresa Vincent,Philip L. Leopold,Alan D. Schreiber,Ronald G. Crystal

View Articletitled, Enhanced Liver Uptake of Opsonized Red Blood Cells After In Vivo Transfer of FcγRIIA cDNA to the Liver

Cloning and Expression of a Short Fas Ligand: A New Alternatively Spliced Product of the Mouse Fas Ligand Gene

Emira Ayroldi,Francesca D’Adamio,Ornella Zollo,Massimiliano Agostini,Rosalba Moraca,Lorenza Cannarile,Graziella Migliorati,Domenico V. Delfino,Carlo Riccardi

View Articletitled, Cloning and Expression of a Short Fas Ligand: A New Alternatively Spliced Product of the Mouse Fas Ligand Gene

Intrathymic Restriction and Peripheral Expansion of the T-Cell Repertoire in Omenn Syndrome

Simona Signorini,Luisa Imberti,Silvia Pirovano,Anna Villa,Fabio Facchetti,Marco Ungari,Fabio Bozzi,Alberto Albertini,Alberto G. Ugazio,Paolo Vezzoni,Luigi D. Notarangelo

View Articletitled, Intrathymic Restriction and Peripheral Expansion of the T-Cell Repertoire in Omenn Syndrome

Effect of Costimulation and the Microenvironment on Antigen Presentation by Leukemic Cells

A.G.S. Buggins,N. Lea,J. Gäken,D. Darling,F. Farzaneh,G.J. Mufti,W.J.R. Hirst

View Articletitled, Effect of Costimulation and the Microenvironment on Antigen Presentation by Leukemic Cells

β-Selection Is Associated With the Onset of CD8β Chain Expression on CD4⁺CD8⁺ Pre-T Cells During Human Intrathymic Development

Yolanda R. Carrasco,César Trigueros,Almudena R. Ramiro,Virginia G. de Yébenes,Marı́a L. Toribio

View Articletitled, β-Selection Is Associated With the Onset of CD8β Chain Expression on CD4+CD8+ Pre-T Cells During Human Intrathymic Development

NEOPLASIA

Adenovirus-Mediated Cytotoxicity of Chronic Lymphocytic Leukemia Cells

Daniel J. Medina,Wendy Sheay,Lauri Goodell,Pamela Kidd,Eileen White,Arnold B. Rabson,Roger K. Strair

View Articletitled, Adenovirus-Mediated Cytotoxicity of Chronic Lymphocytic Leukemia Cells

Lymphomas Expressing ALK Fusion Protein(s) Other Than NPM-ALK

Brunangelo Falini,Karen Pulford,Alessandra Pucciarini,Antonino Carbone,Chris De Wolf-Peeters,Jacqueline Cordell,Marco Fizzotti,Antonella Santucci,Pier-Giuseppe Pelicci,Stefano Pileri,Elias Campo,German Ott,Georges Delsol,David Y. Mason

View Articletitled, Lymphomas Expressing ALK Fusion Protein(s) Other Than NPM-ALK

Analysis of the B-Cell Receptor B29 (CD79b) Gene in Familial Chronic Lymphocytic Leukemia

Béatrice Payelle-Brogard,Christian Magnac,Francesca R. Mauro,Franco Mandelli,Guillaume Dighiero

View Articletitled, Analysis of the B-Cell Receptor B29 (CD79b) Gene in Familial Chronic Lymphocytic Leukemia

Defective Apoptotic Signal Transduction Pathway Downstream of Caspase-3 in Human B-Lymphoma Cells: A Novel Mechanism of Nuclear Apoptosis Resistance

Yoshinari Kawabata,Makoto Hirokawa,Atsushi Kitabayashi,Takahiro Horiuchi,Jun Kuroki,Akira B. Miura

View Articletitled, Defective Apoptotic Signal Transduction Pathway Downstream of Caspase-3 in Human B-Lymphoma Cells: A Novel Mechanism of Nuclear Apoptosis Resistance

Adoptive T-Cell Therapy for B-Cell Acute Lymphoblastic Leukemia: Preclinical Studies

Angelo A. Cardoso,J. Pedro Veiga,Paolo Ghia,Hernani M. Afonso,W. Nicholas Haining,Stephen E. Sallan,Lee M. Nadler

View Articletitled, Adoptive T-Cell Therapy for B-Cell Acute Lymphoblastic Leukemia: Preclinical Studies

Prognostic Implications of the Differentiation Inhibitory Factornm23-H1 Protein in the Plasma of Aggressive Non-Hodgkin’s Lymphoma

Nozomi Niitsu,Junko Okabe-Kado,Takashi Kasukabe,Yuri Yamamoto-Yamaguchi,Masanori Umeda,Yoshio Honma

View Articletitled, Prognostic Implications of the Differentiation Inhibitory Factornm23-H1 Protein in the Plasma of Aggressive Non-Hodgkin’s Lymphoma

Enforced CD19 Expression Leads to Growth Inhibition and Reduced Tumorigenicity

Maged S. Mahmoud,Ryuichi Fujii,Hideaki Ishikawa,Michio M. Kawano

View Articletitled, Enforced CD19 Expression Leads to Growth Inhibition and Reduced Tumorigenicity

Mutational Analysis in Murine Models for Myeloma-Associated Fanconi’s Syndrome or Cast Myeloma Nephropathy

C. Decourt,A. Rocca,F. Bridoux,F. Vrtovsnik,J.L. Preud’homme,M. Cogné,G. Touchard

View Articletitled, Mutational Analysis in Murine Models for Myeloma-Associated Fanconi’s Syndrome or Cast Myeloma Nephropathy

The MAL Gene Is Expressed in Primary Mediastinal Large B-Cell Lymphoma

Christiane Copie-Bergman,Philippe Gaulard,Leı̈la Maouche-Chrétien,Josette Brière,Corinne Haioun,Miguel A. Alonso,Paul-Henri Roméo,Karen Leroy

View Articletitled, The MAL Gene Is Expressed in Primary Mediastinal Large B-Cell Lymphoma

The Proliferative Potential of Myeloma Plasma Cells Manifest in the SCID-hu Host

Shmuel Yaccoby,Joshua Epstein

View Articletitled, The Proliferative Potential of Myeloma Plasma Cells Manifest in the SCID-hu Host

Liposomal ET-18-OCH₃ Induces Cytochrome c-Mediated Apoptosis Independently of CD95 (APO-1/Fas) Signaling

Olivier Cuvillier,Eric Mayhew,Andrew S. Janoff,Sarah Spiegel

View Articletitled, Liposomal ET-18-OCH3 Induces Cytochrome c-Mediated Apoptosis Independently of CD95 (APO-1/Fas) Signaling

RED CELLS

H-Ferritin Subunit Overexpression in Erythroid Cells Reduces the Oxidative Stress Response and Induces Multidrug Resistance Properties

Silvina Epsztejn,Hava Glickstein,Virginie Picard,Itzchak N. Slotki,William Breuer,Carole Beaumont,Z. Ioav Cabantchik

View Articletitled, H-Ferritin Subunit Overexpression in Erythroid Cells Reduces the Oxidative Stress Response and Induces Multidrug Resistance Properties

BRIEF REPORTS

Genetic Evidence of an Accessory Activity Required Specifically for Cubilin Brush-Border Expression and Intrinsic Factor-Cobalamin Absorption

Danbin Xu,Renata Kozyraki,Thomas C. Newman,John C. Fyfe

View Articletitled, Genetic Evidence of an Accessory Activity Required Specifically for Cubilin Brush-Border Expression and Intrinsic Factor-Cobalamin Absorption

CORRESPONDENCE

Primary Plasma Cell Leukemia and Multiple Myeloma: One or Two Diseases According to the Methodology

Nicole Véronique Smadja,Christian Bastard,Christophe Brigaudeau

View Articletitled, Primary Plasma Cell Leukemia and Multiple Myeloma: One or Two Diseases According to the Methodology

Polymerase Chain Reaction Analyses Should Be Used as a Basis for Clinical Decision Making in Patients With Chronic Myelogenous Leukemia

Jana Moravcová,Sylvie Nádvornı́ková,Marcela Lukášová,Hana Klamová

View Articletitled, Polymerase Chain Reaction Analyses Should Be Used as a Basis for Clinical Decision Making in Patients With Chronic Myelogenous Leukemia

von Willebrand Factor Proteolysis in Thrombotic Thrombocytopenic Purpura

Miha Furlan

View Articletitled, von Willebrand Factor Proteolysis in Thrombotic Thrombocytopenic Purpura

Development of the Hematopoietic Stem Cell: Can We Describe It?

Alexander Medvinsky,Elaine Dzierzak

View Articletitled, Development of the Hematopoietic Stem Cell: Can We Describe It?

Complex Variant Translocation t(1;2) WithTPM3-ALK Fusion Due to Cryptic ALK Gene Rearrangement in Anaplastic Large-Cell Lymphoma

Reiner Siebert,Stefan Gesk,Lana Harder,Doris Steinemann,Werner Grote,Brigitte Schlegelberger,Markus Tiemann,Iwona Wlodarska,Verena Schemmel

View Articletitled, Complex Variant Translocation t(1;2) WithTPM3-ALK Fusion Due to Cryptic ALK Gene Rearrangement in Anaplastic Large-Cell Lymphoma

Detection of TT Virus DNA in Plasma-Derived Clotting Factor Concentrates

Shouichi Yokozaki,Yoshihide Fukuda,Isao Nakano,Yoshiaki Katano,Hidenori Toyoda,Junki Takamatsu

View Articletitled, Detection of TT Virus DNA in Plasma-Derived Clotting Factor Concentrates

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Dual Biological Role and Clinical Impact of De Novo Chromatin Activation in Chronic Lymphocytic Leukemia

GATA2 links stemness to chemotherapy resistance in acute myeloid leukemia.

Evaluating the impact of CRBN mutations on response to immunomodulatory drugs and novel CRBN-binding agents in myeloma

Isatuximab, Carfilzomib, Lenalidomide, and Dexamethasone Induction in Newly Diagnosed Myeloma: Analysis of the MIDAS Trial

HSP-CAR30 WITH A HIGH PROPORTION OF LESS-DIFFERENTIATED T CELLS PROMOTES DURABLE RESPONSES IN REFRACTORY CD30+ LYMPHOMA