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Volume 93, Issue 9

May 1 1999

In this Issue

COMMENTARY
REVIEW ARTICLES
RAPID COMMUNICATIONS
CHEMOKINES
CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS
GENE THERAPY
HEMATOPOIESIS
HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY
IMMUNOBIOLOGY
NEOPLASIA
PHAGOCYTES
RED CELLS
TRANSFUSION MEDICINE
CORRESPONDENCE

COMMENTARY

Should Polymerase Chain Reaction Analysis to Detect Minimal Residual Disease in Patients With Chronic Myelogenous Leukemia Be Used in Clinical Decision Making?

Stefan Faderl,Moshe Talpaz,Hagop M. Kantarjian,Zeev Estrov

View Articletitled, Should Polymerase Chain Reaction Analysis to Detect Minimal Residual Disease in Patients With Chronic Myelogenous Leukemia Be Used in Clinical Decision Making?

REVIEW ARTICLES

The SCL Gene: From Case Report to Critical Hematopoietic Regulator

C. Glenn Begley,Anthony R. Green

View Articletitled, The SCL Gene: From Case Report to Critical Hematopoietic Regulator

RAPID COMMUNICATIONS

Mice Homozygous for a Truncated Form of CREB-Binding Protein Exhibit Defects in Hematopoiesis and Vasculo-angiogenesis

Yuichi Oike,Nobuyuki Takakura,Akira Hata,Tadashi Kaname,Miwa Akizuki,Yuji Yamaguchi,Hirofumi Yasue,Kimi Araki,Ken-ichi Yamamura,Toshio Suda

View Articletitled, Mice Homozygous for a Truncated Form of CREB-Binding Protein Exhibit Defects in Hematopoiesis and Vasculo-angiogenesis

Expression of E2A-HLF Chimeric Protein Induced T-Cell Apoptosis, B-Cell Maturation Arrest, and Development of Acute Lymphoblastic Leukemia

Hiroaki Honda,Toshiya Inaba,Takahiro Suzuki,Hideaki Oda,Yasuhiro Ebihara,Kohichiro Tsuiji,Tatsutoshi Nakahata,Takatoshi Ishikawa,Yoshio Yazaki,Hisamaru Hirai

View Articletitled, Expression of E2A-HLF Chimeric Protein Induced T-Cell Apoptosis, B-Cell Maturation Arrest, and Development of Acute Lymphoblastic Leukemia

CHEMOKINES

Mast Cell Migratory Response to Interleukin-8 Is Mediated Through Interaction With Chemokine Receptor CXCR2/Interleukin-8RB

Gunnar Nilsson,Judy A. Mikovits,Dean D. Metcalfe,Dennis D. Taub

View Articletitled, Mast Cell Migratory Response to Interleukin-8 Is Mediated Through Interaction With Chemokine Receptor CXCR2/Interleukin-8RB

CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS

Recombinant Human Thrombopoietin in Combination With Granulocyte Colony-Stimulating Factor Enhances Mobilization of Peripheral Blood Progenitor Cells, Increases Peripheral Blood Platelet Concentration, and Accelerates Hematopoietic Recovery Following High-Dose Chemotherapy

George Somlo,Irena Sniecinski,Anna ter Veer,Jeffrey Longmate,Gaylord Knutson,Stanimir Vuk-Pavlovic,Ravi Bhatia,Warren Chow,Lucille Leong,Robert Morgan,Kim Margolin,James Raschko,Stephen Shibata,Merry Tetef,Yun Yen,Stephen Forman,Dennie Jones,Mark Ashby,Gwen Fyfe,Susan Hellmann,James H. Doroshow

View Articletitled, Recombinant Human Thrombopoietin in Combination With Granulocyte Colony-Stimulating Factor Enhances Mobilization of Peripheral Blood Progenitor Cells, Increases Peripheral Blood Platelet Concentration, and Accelerates Hematopoietic Recovery Following High-Dose Chemotherapy

A Comparison of the Pharmacological Properties of Carbohydrate Remodeled Recombinant and Placental-Derived β-Glucocerebrosidase: Implications for Clinical Efficacy in Treatment of Gaucher Disease

BethAnn Friedman,Kris Vaddi,Constance Preston,Elizabeth Mahon,James R. Cataldo,John M. McPherson

View Articletitled, A Comparison of the Pharmacological Properties of Carbohydrate Remodeled Recombinant and Placental-Derived β-Glucocerebrosidase: Implications for Clinical Efficacy in Treatment of Gaucher Disease

Prognostic Importance of 6-Mercaptopurine Dose Intensity in Acute Lymphoblastic Leukemia

Mary V. Relling,Michael L. Hancock,James M. Boyett,Ching-Hon Pui,William E. Evans

View Articletitled, Prognostic Importance of 6-Mercaptopurine Dose Intensity in Acute Lymphoblastic Leukemia

Rapid Telomere Shortening in Children

Steven L. Zeichner,Paul Palumbo,YanRu Feng,Xiaodong Xiao,Dennis Gee,John Sleasman,Maureen Goodenow,Robert Biggar,Dimiter Dimitrov

View Articletitled, Rapid Telomere Shortening in Children

Allogeneic Stem Cell Transplantation for Agnogenic Myeloid Metaplasia: A European Group for Blood and Marrow Transplantation, Société Française de Greffe de Moelle, Gruppo Italiano per il Trapianto del Midollo Osseo, and Fred Hutchinson Cancer Research Center Collaborative Study

Philippe Guardiola,Jeanne E. Anderson,Giuseppe Bandini,Francisco Cervantes,Volker Runde,William Arcese,Andrea Bacigalupo,Donna Przepiorka,Margaret R. O’Donnell,Paola Polchi,Agnès Buzyn,Laurent Sutton,Dominique Cazals-Hatem,George Sale,Theo de Witte,H. Joachim Deeg,Eliane Gluckman,for the International Collaboration for Transplantation in Agnogenic Myeloid Metaplasia

View Articletitled, Allogeneic Stem Cell Transplantation for Agnogenic Myeloid Metaplasia: A European Group for Blood and Marrow Transplantation, Société Française de Greffe de Moelle, Gruppo Italiano per il Trapianto del Midollo Osseo, and Fred Hutchinson Cancer Research Center Collaborative Study

GENE THERAPY

The Common Marmoset as a Target Preclinical Primate Model for Cytokine and Gene Therapy Studies

Hitoshi Hibino,Kenzaburo Tani,Kenji Ikebuchi,Ming-Shiuan Wu,Hajime Sugiyama,Yukoh Nakazaki,Tsuyoshi Tanabe,Satoshi Takahashi,Arinobu Tojo,Shuzo Suzuki,Yoshikuni Tanioka,Yoshikazu Sugimoto,Tatsutoshi Nakahata,Shigetaka Asano

View Articletitled, The Common Marmoset as a Target Preclinical Primate Model for Cytokine and Gene Therapy Studies

HEMATOPOIESIS

Commitment to the Monocytic Lineage Occurs in the Absence of the Transcription Factor PU.1

Gregory W. Henkel,Scott R. McKercher,Pieter J.M. Leenen,Richard A. Maki

View Articletitled, Commitment to the Monocytic Lineage Occurs in the Absence of the Transcription Factor PU.1

High-Level Expression of Mpl in Platelets and Megakaryocytes Is Independent of Thrombopoietin

Karine Cohen-Solal,Natacha Vitrat,Monique Titeux,William Vainchenker,Françoise Wendling

View Articletitled, High-Level Expression of Mpl in Platelets and Megakaryocytes Is Independent of Thrombopoietin

Consequences of GATA-1 Deficiency in Megakaryocytes and Platelets

Paresh Vyas,Kenneth Ault,Carl W. Jackson,Stuart H. Orkin,Ramesh A. Shivdasani

View Articletitled, Consequences of GATA-1 Deficiency in Megakaryocytes and Platelets

Expression of a Functional N-Methyl-d-Aspartate–Type Glutamate Receptor by Bone Marrow Megakaryocytes

Paul G. Genever,David J.P. Wilkinson,Amanda J. Patton,Nicky M. Peet,Ying Hong,Anthony Mathur,Jorge D. Erusalimsky,Tim M. Skerry

View Articletitled, Expression of a Functional N-Methyl-d-Aspartate–Type Glutamate Receptor by Bone Marrow Megakaryocytes

Heparan Sulfate Proteoglycan Expression Is Induced During Early Erythroid Differentiation of Multipotent Hematopoietic Stem Cells

Zofia Drzeniek,Georg Stöcker,Barbara Siebertz,Ursula Just,Timm Schroeder,Wolfram Ostertag,Hans-Dieter Haubeck

View Articletitled, Heparan Sulfate Proteoglycan Expression Is Induced During Early Erythroid Differentiation of Multipotent Hematopoietic Stem Cells

Glycoprotein IIb-IIIa Is Expressed on Avian Multilineage Hematopoietic Progenitor Cells

Christiane Ody,Pierre Vaigot,Pascale Quéré,Beat A. Imhof,Catherine Corbel

View Articletitled, Glycoprotein IIb-IIIa Is Expressed on Avian Multilineage Hematopoietic Progenitor Cells

Subcellular and Cell-Cycle Expression Profiles of CDK-Inhibitors in Normal Differentiating Myeloid Cells

B. Yaroslavskiy,S. Watkins,A.D. Donnenberg,T.J. Patton,R.A. Steinman

View Articletitled, Subcellular and Cell-Cycle Expression Profiles of CDK-Inhibitors in Normal Differentiating Myeloid Cells

Potential Role for Hyaluronan and the Hyaluronan Receptor RHAMM in Mobilization and Trafficking of Hematopoietic Progenitor Cells

Linda M. Pilarski,Eva Pruski,Juanita Wizniak,Darlene Paine,Karen Seeberger,Michael J. Mant,Christopher B. Brown,Andrew R. Belch

View Articletitled, Potential Role for Hyaluronan and the Hyaluronan Receptor RHAMM in Mobilization and Trafficking of Hematopoietic Progenitor Cells

Hematopoietic Growth Factors Signal Through the Formation of Reactive Oxygen Species

Martin Sattler,Thomas Winkler,Shalini Verma,Christopher H. Byrne,Gautam Shrikhande,Ravi Salgia,James D. Griffin

View Articletitled, Hematopoietic Growth Factors Signal Through the Formation of Reactive Oxygen Species

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

E1⁻E4⁺ Adenoviral Gene Transfer Vectors Function as a “Pro-Life” Signal to Promote Survival of Primary Human Endothelial Cells

Ramachandran Ramalingam,Shahin Rafii,Stefan Worgall,Douglas E. Brough,Ronald G. Crystal

View Articletitled, E1−E4+ Adenoviral Gene Transfer Vectors Function as a “Pro-Life” Signal to Promote Survival of Primary Human Endothelial Cells

Vitamin E Reduces Monocyte Tissue Factor Expression in Cirrhotic Patients

Domenico Ferro,Stefania Basili,Domenico Praticó,Luigi Iuliano,Garret A. FitzGerald,Francesco Violi

View Articletitled, Vitamin E Reduces Monocyte Tissue Factor Expression in Cirrhotic Patients

Direct Evidence of Endothelial Injury in Acute Myocardial Infarction and Unstable Angina by Demonstration of Circulating Endothelial Cells

Murielle Mutin,Isabelle Canavy,Andrew Blann,Michel Bory,José Sampol,Françoise Dignat-George

View Articletitled, Direct Evidence of Endothelial Injury in Acute Myocardial Infarction and Unstable Angina by Demonstration of Circulating Endothelial Cells

Construction of a Human Platelet Alloantigen-1a Epitope(s) Within Murine Glycoprotein IIIa: Identification of Residues Critical to the Conformation of the Antibody Binding Site(s): Presented in part at the American Society of Hematology meeting, December 5-9, 1997, San Diego, CA.

Emily A. Barron-Casella,Gaia Nebbia,Ophelia C. Rogers,Karen E. King,Thomas S. Kickler,James F. Casella

View Articletitled, Construction of a Human Platelet Alloantigen-1a Epitope(s) Within Murine Glycoprotein IIIa: Identification of Residues Critical to the Conformation of the Antibody Binding Site(s): Presented in part at the American Society of Hematology meeting, December 5-9, 1997, San Diego, CA.

The Critical Interaction of Glycoprotein (GP) Ibβ With GPIX—A Genetic Cause of Bernard-Soulier Syndrome

Dermot Kenny,Patricia A. Morateck,Joan C. Gill,Robert R. Montgomery

View Articletitled, The Critical Interaction of Glycoprotein (GP) Ibβ With GPIX—A Genetic Cause of Bernard-Soulier Syndrome

Molecular Mechanisms of Zinc-Dependent Leukocyte Adhesion Involving the Urokinase Receptor and β₂-Integrins

Triantafyllos Chavakis,Andreas E. May,Klaus T. Preissner,Sandip M. Kanse

View Articletitled, Molecular Mechanisms of Zinc-Dependent Leukocyte Adhesion Involving the Urokinase Receptor and β2-Integrins

Sphingosine 1-Phosphate Stimulates Fibronectin Matrix Assembly Through a Rho-Dependent Signal Pathway

Qinghong Zhang,Olivier Peyruchaud,Kelly J. French,Magnus K. Magnusson,Deane F. Mosher

View Articletitled, Sphingosine 1-Phosphate Stimulates Fibronectin Matrix Assembly Through a Rho-Dependent Signal Pathway

Fibrates Suppress Fibrinogen Gene Expression in Rodents Via Activation of the Peroxisome Proliferator-Activated Receptor-

Maaike Kockx,Philippe P. Gervois,Philippe Poulain,Bruno Derudas,Jeffrey M. Peters,Frank J. Gonzalez,Hans M.G. Princen,Teake Kooistra,Bart Staels

View Articletitled, Fibrates Suppress Fibrinogen Gene Expression in Rodents Via Activation of the Peroxisome Proliferator-Activated Receptor-

IMMUNOBIOLOGY

Inhibition of Human Breast Carcinoma Growth by a Soluble Recombinant Human CD40 Ligand

Akio Hirano,Dan L. Longo,Dennis D. Taub,Douglas K. Ferris,Lawrence S. Young,Arisitides G. Eliopoulos,Angelo Agathanggelou,Nicky Cullen,James Macartney,William C. Fanslow,William J. Murphy

View Articletitled, Inhibition of Human Breast Carcinoma Growth by a Soluble Recombinant Human CD40 Ligand

Characterization of T-Cell Repertoire of the Bone Marrow in Immune-Mediated Aplastic Anemia: Evidence for the Involvement of Antigen-Driven T-Cell Response in Cyclosporine-Dependent Aplastic Anemia

Weihua Zeng,Shinji Nakao,Hideyuki Takamatsu,Akihiro Yachie,Akiyoshi Takami,Yukio Kondo,Naomi Sugimori,Hirohito Yamazaki,Yuji Miura,Shintaro Shiobara,Tamotsu Matsuda

View Articletitled, Characterization of T-Cell Repertoire of the Bone Marrow in Immune-Mediated Aplastic Anemia: Evidence for the Involvement of Antigen-Driven T-Cell Response in Cyclosporine-Dependent Aplastic Anemia

Promoter Element for Transcription of Unrearranged T-Cell Receptor β-Chain Gene in Pro-T Cells

Raymond T. Doty,Dong Xia,Suzanne P. Nguyen,Tanya R. Hathaway,Dennis M. Willerford

View Articletitled, Promoter Element for Transcription of Unrearranged T-Cell Receptor β-Chain Gene in Pro-T Cells

Expression of Epstein-Barr Virus BamHI-A Rightward Transcripts in Latently Infected B Cells From Peripheral Blood

Honglin Chen,Paul Smith,Richard F. Ambinder,S. Diane Hayward

View Articletitled, Expression of Epstein-Barr Virus BamHI-A Rightward Transcripts in Latently Infected B Cells From Peripheral Blood

TCR Gene Rearrangements and Expression of the Pre-T Cell Receptor Complex During Human T-Cell Differentiation

Bianca Blom,Martie C.M. Verschuren,Mirjam H.M. Heemskerk,Arjen Q. Bakker,Ellen J. van Gastel-Mol,Ingrid L.M. Wolvers-Tettero,Jacques J.M. van Dongen,Hergen Spits

View Articletitled, TCR Gene Rearrangements and Expression of the Pre-T Cell Receptor Complex During Human T-Cell Differentiation

NEOPLASIA

Role of NF-κB in the Rescue of Multiple Myeloma Cells From Glucocorticoid-Induced Apoptosis by Bcl-2

Rena Feinman,Jadd Koury,Michael Thames,Bart Barlogie,Joshua Epstein,David S. Siegel

View Articletitled, Role of NF-κB in the Rescue of Multiple Myeloma Cells From Glucocorticoid-Induced Apoptosis by Bcl-2

Anticancer Drugs Induce Caspase-8/FLICE Activation and Apoptosis in the Absence of CD95 Receptor/Ligand Interaction

Sebastian Wesselborg,Ingo H. Engels,Evi Rossmann,Marek Los,Klaus Schulze-Osthoff

View Articletitled, Anticancer Drugs Induce Caspase-8/FLICE Activation and Apoptosis in the Absence of CD95 Receptor/Ligand Interaction

Bone Marrow Neovascularization, Plasma Cell Angiogenic Potential, and Matrix Metalloproteinase-2 Secretion Parallel Progression of Human Multiple Myeloma

Angelo Vacca,Domenico Ribatti,Marco Presta,Monica Minischetti,Monica Iurlaro,Roberto Ria,Adriana Albini,Federico Bussolino,Franco Dammacco

View Articletitled, Bone Marrow Neovascularization, Plasma Cell Angiogenic Potential, and Matrix Metalloproteinase-2 Secretion Parallel Progression of Human Multiple Myeloma

Prognostic Implication of FLT3 and N-RAS Gene Mutations in Acute Myeloid Leukemia

Hitoshi Kiyoi,Tomoki Naoe,Yasuyuki Nakano,Shohei Yokota,Saburo Minami,Shuichi Miyawaki,Norio Asou,Kazutaka Kuriyama,Itsuro Jinnai,Chihiro Shimazaki,Hideki Akiyama,Kenji Saito,Hakumei Oh,Toshiko Motoji,Eijiro Omoto,Hidehiko Saito,Ryuzo Ohno,Ryuzo Ueda

View Articletitled, Prognostic Implication of FLT3 and N-RAS Gene Mutations in Acute Myeloid Leukemia

Correlation of Bcl-2 Rearrangement With Clinical Characteristics and Outcome in Indolent Follicular Lymphoma

Armando López-Guillermo,Fernando Cabanillas,Timothy I. McDonnell,Peter McLaughlin,Terry Smith,William Pugh,Fredrick Hagemeister,M. Alma Rodrı́guez,Jorge E. Romaguera,Anas Younes,Andreas H. Sarris,H. Alejandro Preti,Ming-Seng Lee

View Articletitled, Correlation of Bcl-2 Rearrangement With Clinical Characteristics and Outcome in Indolent Follicular Lymphoma

A New Fusion Gene TPM3-ALK in Anaplastic Large Cell Lymphoma Created by a (1;2)(q25;p23) Translocation

Laurence Lamant,Nicole Dastugue,Karen Pulford,Georges Delsol,Bernard Mariamé

View Articletitled, A New Fusion Gene TPM3-ALK in Anaplastic Large Cell Lymphoma Created by a (1;2)(q25;p23) Translocation

PHAGOCYTES

CCAAT/Enhancer Binding Protein ɛ Is Critical for Effective Neutrophil-Mediated Response to Inflammatory Challenge

Julie Lekstrom-Himes,Kleanthis G. Xanthopoulos

View Articletitled, CCAAT/Enhancer Binding Protein ɛ Is Critical for Effective Neutrophil-Mediated Response to Inflammatory Challenge

Bcl-X_l– and Bax-–Mediated Regulation of Apoptosis of Human Neutrophils Via Caspase-3

Pamela Weinmann,Peter Gaehtgens,Barbara Walzog

View Articletitled, Bcl-Xl– and Bax-–Mediated Regulation of Apoptosis of Human Neutrophils Via Caspase-3

RED CELLS

Impairment of Plasmodium falciparum Growth in Thalassemic Red Blood Cells: Further Evidence by Using Biotin Labeling and Flow Cytometry

Kovit Pattanapanyasat,Kosol Yongvanitchit,Pongsri Tongtawe,Kalaya Tachavanich,Wanchai Wanachiwanawin,Suthat Fucharoen,Douglas S. Walsh

View Articletitled, Impairment of Plasmodium falciparum Growth in Thalassemic Red Blood Cells: Further Evidence by Using Biotin Labeling and Flow Cytometry

Familial Pseudohyperkalemia Maps to the Same Locus as Dehydrated Hereditary Stomatocytosis (Hereditary Xerocytosis)

A. Iolascon,G.W. Stewart,J.F. Ajetunmobi,S. Perrotta,J. Delaunay,M. Carella,L. Zelante,P. Gasparini

View Articletitled, Familial Pseudohyperkalemia Maps to the Same Locus as Dehydrated Hereditary Stomatocytosis (Hereditary Xerocytosis)

TRANSFUSION MEDICINE

A Restrictive Platelet Transfusion Policy Allowing Long-Term Support of Outpatients With Severe Aplastic Anemia

Markus Sagmeister,Lic Oec,Jürg Gmür

View Articletitled, A Restrictive Platelet Transfusion Policy Allowing Long-Term Support of Outpatients With Severe Aplastic Anemia

Survival of Donor Leukocyte Subpopulations in Immunocompetent Transfusion Recipients: Frequent Long-Term Microchimerism in Severe Trauma Patients

Tzong-Hae Lee,Teresa Paglieroni,Hitoshi Ohto,Paul V. Holland,Michael P. Busch

View Articletitled, Survival of Donor Leukocyte Subpopulations in Immunocompetent Transfusion Recipients: Frequent Long-Term Microchimerism in Severe Trauma Patients

Prevention of Transfusion-Associated Graft-Versus-Host Disease by Photochemical Treatment

Joshua A. Grass,Tamim Wafa,Aaron Reames,David Wages,Laurence Corash,James L.M. Ferrara,Lily Lin

View Articletitled, Prevention of Transfusion-Associated Graft-Versus-Host Disease by Photochemical Treatment

CORRESPONDENCE

“Stochastic”—40 Years of Use and Abuse

Nicolas Blackett,Myrtle Gordon

View Articletitled, “Stochastic”—40 Years of Use and Abuse

Effect of Complete Remission on Survival in Patients With Acute Myelogenous Leukemia Receiving First Salvage Therapy

Norbert Vey,Michael Keating,Francis Giles,Jorge Cortes,Miloslav Beran,Elihu Estey

View Articletitled, Effect of Complete Remission on Survival in Patients With Acute Myelogenous Leukemia Receiving First Salvage Therapy

The 20210A Allele of the Prothrombin Gene Is an Independent Risk Factor for Perception Deafness in Patients With Venous Thromboembolic Antecedents

Eric Mercier,Isabelle Quere,René Chabert,Jean-Gabriel Lallemant,Jean-Pierre Daures,Jacques Berlan,Jean-Christophe Gris

View Articletitled, The 20210A Allele of the Prothrombin Gene Is an Independent Risk Factor for Perception Deafness in Patients With Venous Thromboembolic Antecedents

Where Does Platelet Factor V Originate?

Robert W. Colman

View Articletitled, Where Does Platelet Factor V Originate?

Hormonal Therapy After Stem Cell Transplantation and the Risk of Veno-occlusive Disease

Simona Sica,Prassede Salutari,Patrizia Chiusolo,Silvia Cicconi,Federica Sorá,Luca Laurenti,Nicola Piccirillo,Paola Scirpa,Giuseppe Leone

View Articletitled, Hormonal Therapy After Stem Cell Transplantation and the Risk of Veno-occlusive Disease

Is Complicated Celiac Disease or Refractory Sprue an Intestinal Intra-Epithelial Cryptic T-Cell Lymphoma?

Nicole Brousse,Virginie Verkarre,Natacha Patey-Mariaud de Serre,Christophe Cellier,Nadine Cerf-Bensussan,Eric Delabesse,Elisabeth Macintyre

View Articletitled, Is Complicated Celiac Disease or Refractory Sprue an Intestinal Intra-Epithelial Cryptic T-Cell Lymphoma?

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