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Volume 93, Issue 8

April 15 1999

In this Issue

REVIEW ARTICLES
RAPID COMMUNICATIONS
CHEMOKINES
CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS
HEMATOPOIESIS
HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY
IMMUNOBIOLOGY
NEOPLASIA
PHAGOCYTES
TRANSPLANTATION
CORRESPONDENCE
ERRATA

REVIEW ARTICLES

Notch as a Mediator of Cell Fate Determination in Hematopoiesis: Evidence and Speculation

Laurie A. Milner,Anna Bigas

View Articletitled, Notch as a Mediator of Cell Fate Determination in Hematopoiesis: Evidence and Speculation

RAPID COMMUNICATIONS

Association of the Platelet Glycoprotein Ia C₈₀₇T Gene Polymorphism With Nonfatal Myocardial Infarction in Younger Patients

S. Santoso,T.J. Kunicki,H. Kroll,W. Haberbosch,A. Gardemann

View Articletitled, Association of the Platelet Glycoprotein Ia C807T Gene Polymorphism With Nonfatal Myocardial Infarction in Younger Patients

A CD4-Independent Interaction of Human Immunodeficiency Virus-1 gp120 With CXCR4 Induces Their Cointernalization, Cell Signaling, and T-Cell Chemotaxis

Dorothée Missé,Martine Cerutti,Nelly Noraz,Patrick Jourdan,Jean Favero,Gérard Devauchelle,Hans Yssel,Naomi Taylor,Francisco Veas

View Articletitled, A CD4-Independent Interaction of Human Immunodeficiency Virus-1 gp120 With CXCR4 Induces Their Cointernalization, Cell Signaling, and T-Cell Chemotaxis

CHEMOKINES

Differential Chemokine Expression in Tissues Involved by Hodgkin’s Disease: Direct Correlation of Eotaxin Expression and Tissue Eosinophilia: Presented in part at the 39th Annual Meeting of the American Society of Hematology, held in San Diego, CA, December 5-9, 1997.

Julie Teruya-Feldstein,Elaine S. Jaffe,Parris R. Burd,Douglas W. Kingma,Joyce E. Setsuda,Giovanna Tosato

View Articletitled, Differential Chemokine Expression in Tissues Involved by Hodgkin’s Disease: Direct Correlation of Eotaxin Expression and Tissue Eosinophilia: Presented in part at the 39th Annual Meeting of the American Society of Hematology, held in San Diego, CA, December 5-9, 1997.

CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS

Filgrastim for Cladribine-Induced Neutropenic Fever in Patients With Hairy Cell Leukemia

Alan Saven,Carol Burian,Jasvant Adusumalli,James A. Koziol

View Articletitled, Filgrastim for Cladribine-Induced Neutropenic Fever in Patients With Hairy Cell Leukemia

Randomized Phase II Study of Fludarabine + Cytosine Arabinoside + Idarubicin ± All-Trans Retinoic Acid ± Granulocyte Colony-Stimulating Factor in Poor Prognosis Newly Diagnosed Acute Myeloid Leukemia and Myelodysplastic Syndrome

Elihu H. Estey,Peter F. Thall,Sherry Pierce,Jorge Cortes,Miloslav Beran,Hagop Kantarjian,Michael J. Keating,Michael Andreeff,Emil Freireich

View Articletitled, Randomized Phase II Study of Fludarabine + Cytosine Arabinoside + Idarubicin ± All-Trans Retinoic Acid ± Granulocyte Colony-Stimulating Factor in Poor Prognosis Newly Diagnosed Acute Myeloid Leukemia and Myelodysplastic Syndrome

TT Virus in Bone Marrow Transplant Recipients

Yoshinobu Kanda,Yuji Tanaka,Masahiro Kami,Toshiki Saito,Takashi Asai,Koji Izutsu,Koichiro Yuji,Seishi Ogawa,Hiroaki Honda,Kinuko Mitani,Shigeru Chiba,Yoshio Yazaki,Hisamaru Hirai

View Articletitled, TT Virus in Bone Marrow Transplant Recipients

A Randomized Phase 3 Study of Peripheral Blood Progenitor Cell Mobilization With Stem Cell Factor and Filgrastim in High-Risk Breast Cancer Patients

Elizabeth J. Shpall,Catherine A. Wheeler,Stewart A. Turner,Saul Yanovich,Randy A. Brown,Andrew L. Pecora,Thomas C. Shea,Kenneth F. Mangan,Stephanie F. Williams,C. Fred LeMaistre,Gwynn D. Long,Roy Jones,Mark W. Davis,Robyn Murphy-Filkins,William R.L. Parker,John A. Glaspy

View Articletitled, A Randomized Phase 3 Study of Peripheral Blood Progenitor Cell Mobilization With Stem Cell Factor and Filgrastim in High-Risk Breast Cancer Patients

HFE Mutations Analysis in 711 Hemochromatosis Probands: Evidence for S65C Implication in Mild Form of Hemochromatosis

Catherine Mura,Odile Raguenes,Claude Férec

View Articletitled, HFE Mutations Analysis in 711 Hemochromatosis Probands: Evidence for S65C Implication in Mild Form of Hemochromatosis

Neutrophil Activation and Hemostatic Changes in Healthy Donors Receiving Granulocyte Colony-Stimulating Factor

A. Falanga,M. Marchetti,V. Evangelista,S. Manarini,E. Oldani,S. Giovanelli,M. Galbusera,C. Cerletti,T. Barbui

View Articletitled, Neutrophil Activation and Hemostatic Changes in Healthy Donors Receiving Granulocyte Colony-Stimulating Factor

HEMATOPOIESIS

Tissue Uptake of Circulating Thrombopoietin Is Increased in Immune-Mediated Compared With Irradiated Thrombocytopenic Mice: Presented in part at the Annual Meeting of the American Society of Hematology, December 1996, Orlando, FL, and December 1997, San Diego, CA.

Mei Chang,John X. Qian,Sun min Lee,John Joubran,George Fernandez,Jacqueline Nichols,Annika Knoppel,Jeffrey S. Buzby

View Articletitled, Tissue Uptake of Circulating Thrombopoietin Is Increased in Immune-Mediated Compared With Irradiated Thrombocytopenic Mice: Presented in part at the Annual Meeting of the American Society of Hematology, December 1996, Orlando, FL, and December 1997, San Diego, CA.

Soluble Interleukin-6 (IL-6) Receptor With IL-6 Stimulates Megakaryopoiesis From Human CD34⁺ Cells Through Glycoprotein (gp)130 Signaling

Xingwei Sui,Kohichiro Tsuji,Yasuhiro Ebihara,Ryuhei Tanaka,Kenji Muraoka,Makoto Yoshida,Kaoru Yamada,Kiyoshi Yasukawa,Tetsuya Taga,Tadamitsu Kishimoto,Tatsutoshi Nakahata

View Articletitled, Soluble Interleukin-6 (IL-6) Receptor With IL-6 Stimulates Megakaryopoiesis From Human CD34+ Cells Through Glycoprotein (gp)130 Signaling

Characterization of Bone Marrow Laminins and Identification of 5-Containing Laminins as Adhesive Proteins for Multipotent Hematopoietic FDCP-Mix Cells

Yuchen Gu,Lydia Sorokin,Madeleine Durbeej,Tord Hjalt,Jan-Ingvar Jönsson,Marja Ekblom

View Articletitled, Characterization of Bone Marrow Laminins and Identification of 5-Containing Laminins as Adhesive Proteins for Multipotent Hematopoietic FDCP-Mix Cells

Functional Expression of the High Affinity Receptor for IgE (FcɛRI) in Human Platelets and Its’ Intracellular Expression in Human Megakaryocytes

Shunji Hasegawa,Ruby Pawankar,Katsuhiro Suzuki,Tatsutoshi Nakahata,Susumu Furukawa,Ko Okumura,Chisei Ra

View Articletitled, Functional Expression of the High Affinity Receptor for IgE (FcɛRI) in Human Platelets and Its’ Intracellular Expression in Human Megakaryocytes

Cleavage of Factor V at Arg 506 by Activated Protein C and the Expression of Anticoagulant Activity of Factor V

Elisabeth Thorelli,Randal J. Kaufman,Björn Dahlbäck

View Articletitled, Cleavage of Factor V at Arg 506 by Activated Protein C and the Expression of Anticoagulant Activity of Factor V

A Mutation in the Extracellular Cysteine-Rich Repeat Region of the β₃ Subunit Activates Integrins _IIbβ₃ and _Vβ₃

Hirokazu Kashiwagi,Yoshiaki Tomiyama,Seiji Tadokoro,Shigenori Honda,Masamichi Shiraga,Hajime Mizutani,Makoto Handa,Yoshiyuki Kurata,Yuji Matsuzawa,Sanford J. Shattil

View Articletitled, A Mutation in the Extracellular Cysteine-Rich Repeat Region of the β3 Subunit Activates Integrins IIbβ3 and Vβ3

Optimal Proliferation of a Hematopoietic Progenitor Cell Line Requires Either Costimulation With Stem Cell Factor or Increase of Receptor Expression That Can Be Replaced by Overexpression of Bcl-2

Huei-Mei Huang,Jian-Chiuan Li,Yueh-Chun Hsieh,Hsin-Fang Yang-Yen,Jeffrey Jong-Young Yen

View Articletitled, Optimal Proliferation of a Hematopoietic Progenitor Cell Line Requires Either Costimulation With Stem Cell Factor or Increase of Receptor Expression That Can Be Replaced by Overexpression of Bcl-2

Erythropoietin Induces the Tyrosine Phosphorylation of GAB1 and Its Association With SHC, SHP2, SHIP, and Phosphatidylinositol 3-Kinase

Carinne Lecoq-Lafon,Frédérique Verdier,Serge Fichelson,Stany Chrétien,Sylvie Gisselbrecht,Catherine Lacombe,Patrick Mayeux

View Articletitled, Erythropoietin Induces the Tyrosine Phosphorylation of GAB1 and Its Association With SHC, SHP2, SHIP, and Phosphatidylinositol 3-Kinase

Stromal Cell CD9 Regulates Differentiation of Hematopoietic Stem/Progenitor Cells

Keisuke Aoyama,Kenji Oritani,Takafumi Yokota,Jun Ishikawa,Tetsuo Nishiura,Kensuke Miyake,Yuzuru Kanakura,Yoshiaki Tomiyama,Paul W. Kincade,Yuji Matsuzawa

View Articletitled, Stromal Cell CD9 Regulates Differentiation of Hematopoietic Stem/Progenitor Cells

Mechanism of flt3 Ligand Expression in Bone Marrow Failure: Translocation From Intracellular Stores to the Surface of T Lymphocytes After Chemotherapy-Induced Suppression of Hematopoiesis

Elena Chklovskaia,Wendy Jansen,Catherine Nissen,Stewart D. Lyman,Christoph Rahner,Lukas Landmann,Aleksandra Wodnar-Filipowicz

View Articletitled, Mechanism of flt3 Ligand Expression in Bone Marrow Failure: Translocation From Intracellular Stores to the Surface of T Lymphocytes After Chemotherapy-Induced Suppression of Hematopoiesis

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

Identification and Characterization of Endothelial Glycoprotein Ib Using Viper Venom Proteins Modulating Cell Adhesion

Li Tan,M. Anna Kowalska,Gabriel M. Romo,Jose A. Lopez,Zbigniew Darzynkiewicz,Stefan Niewiarowski

View Articletitled, Identification and Characterization of Endothelial Glycoprotein Ib Using Viper Venom Proteins Modulating Cell Adhesion

Human Platelets Contain SNARE Proteins and a Sec1p Homologue That Interacts With Syntaxin 4 and Is Phosphorylated After Thrombin Activation: Implications for Platelet Secretion: Presented in part at the American Heart Association Meeting, November 1996.

Guy L. Reed,Aiilyan K. Houng,Michael L. Fitzgerald

View Articletitled, Human Platelets Contain SNARE Proteins and a Sec1p Homologue That Interacts With Syntaxin 4 and Is Phosphorylated After Thrombin Activation: Implications for Platelet Secretion: Presented in part at the American Heart Association Meeting, November 1996.

Human Erythropoietin Induces a Pro-Angiogenic Phenotype in Cultured Endothelial Cells and Stimulates Neovascularization In Vivo

Domenico Ribatti,Marco Presta,Angelo Vacca,Roberto Ria,Roberta Giuliani,Patrizia Dell’Era,Beatrice Nico,Luisa Roncali,Franco Dammacco

View Articletitled, Human Erythropoietin Induces a Pro-Angiogenic Phenotype in Cultured Endothelial Cells and Stimulates Neovascularization In Vivo

Regulation of the Megakaryocytic Glycoprotein IX Promoter by the Oncogenic Ets Transcription Factor Fli-1

L. Scot Bastian,Boguslaw A. Kwiatkowski,John Breininger,Susan Danner,Gerald Roth

View Articletitled, Regulation of the Megakaryocytic Glycoprotein IX Promoter by the Oncogenic Ets Transcription Factor Fli-1

Genetic and Pharmacological Analyses of Syk Function in _IIbβ₃ Signaling in Platelets

Debbie A. Law,Lisa Nannizzi-Alaimo,Kathleen Ministri,Paul E. Hughes,Jane Forsyth,Martin Turner,Sanford J. Shattil,Mark H. Ginsberg,Victor L.J. Tybulewicz,David R. Phillips

View Articletitled, Genetic and Pharmacological Analyses of Syk Function in IIbβ3 Signaling in Platelets

IMMUNOBIOLOGY

Immunization With Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor as a Vaccine Adjuvant Elicits Both a Cellular and Humoral Response to Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor

Douglas G. McNeel,Kathy Schiffman,Mary L. Disis

View Articletitled, Immunization With Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor as a Vaccine Adjuvant Elicits Both a Cellular and Humoral Response to Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor

Functional Fas Expression in Human Thymic Epithelial Cells

Nathalie Moulian,Claire Renvoizé,Colette Desodt,Alain Serraf,Sonia Berrih-Aknin

View Articletitled, Functional Fas Expression in Human Thymic Epithelial Cells

NEOPLASIA

Increased BAX Expression Is Associated With an Increased Risk of Relapse in Childhood Acute Lymphocytic Leukemia

Linda A. Hogarth,Andrew G. Hall

View Articletitled, Increased BAX Expression Is Associated With an Increased Risk of Relapse in Childhood Acute Lymphocytic Leukemia

Molecular Analysis of Single B Cells From T-Cell–Rich B-Cell Lymphoma Shows the Derivation of the Tumor Cells From Mutating Germinal Center B Cells and Exemplifies Means by Which Immunoglobulin Genes Are Modified in Germinal Center B Cells

Andreas Bräuninger,Ralf Küppers,Tilmann Spieker,Reiner Siebert,John G. Strickler,Brigitte Schlegelberger,Klaus Rajewsky,Martin-Leo Hansmann

View Articletitled, Molecular Analysis of Single B Cells From T-Cell–Rich B-Cell Lymphoma Shows the Derivation of the Tumor Cells From Mutating Germinal Center B Cells and Exemplifies Means by Which Immunoglobulin Genes Are Modified in Germinal Center B Cells

Adverse Effects of Activated Cytotoxic T Lymphocytes on the Clinical Outcome of Nodal Anaplastic Large Cell Lymphoma

Rosita L. ten Berge,Danny F. Dukers,Joost J. Oudejans,Karen Pulford,Gert J. Ossenkoppele,Daphne de Jong,Jo F.M.M. Miseré,Chris J.L.M. Meijer

View Articletitled, Adverse Effects of Activated Cytotoxic T Lymphocytes on the Clinical Outcome of Nodal Anaplastic Large Cell Lymphoma

ALK⁺ Lymphoma: Clinico-Pathological Findings and Outcome

Brunangelo Falini,Stefano Pileri,Pier Luigi Zinzani,Antonino Carbone,Vittorina Zagonel,Chris Wolf-Peeters,Gregor Verhoef,Fabio Menestrina,Giuseppe Todeschini,Marco Paulli,Mario Lazzarino,Roberto Giardini,Antonella Aiello,Hans-Dieter Foss,Iguacyra Araujo,Marco Fizzotti,Pier-Giuseppe Pelicci,Leonardo Flenghi,Massimo F. Martelli,Antonella Santucci

View Articletitled, ALK+ Lymphoma: Clinico-Pathological Findings and Outcome

A Novel SH2-Containing Phosphatidylinositol 3,4,5-Trisphosphate 5-Phosphatase (SHIP2) Is Constitutively Tyrosine Phosphorylated and Associated With src Homologous and Collagen Gene (SHC) in Chronic Myelogenous Leukemia Progenitor Cells

David Wisniewski,Annabel Strife,Steve Swendeman,Hediye Erdjument-Bromage,Scott Geromanos,W. Michael Kavanaugh,Paul Tempst,Bayard Clarkson

View Articletitled, A Novel SH2-Containing Phosphatidylinositol 3,4,5-Trisphosphate 5-Phosphatase (SHIP2) Is Constitutively Tyrosine Phosphorylated and Associated With src Homologous and Collagen Gene (SHC) in Chronic Myelogenous Leukemia Progenitor Cells

PHAGOCYTES

Induced Differentiation of U937 Cells by 1,25-dihydroxyvitamin D₃ Involves Cell Cycle Arrest in G1 That Is Preceded by a Transient Proliferative Burst and an Increase in Cyclin Expression

Nynke Y. Rots,Antonio Iavarone,Virginia Bromleigh,Leonard P. Freedman

View Articletitled, Induced Differentiation of U937 Cells by 1,25-dihydroxyvitamin D3 Involves Cell Cycle Arrest in G1 That Is Preceded by a Transient Proliferative Burst and an Increase in Cyclin Expression

The Effect of Glucocorticoids on the Expression of L-Selectin on Polymorphonuclear Leukocyte

Motohito Nakagawa,Gregory P. Bondy,Dan Waisman,Diane Minshall,James C. Hogg,Stephan F. van Eeden

View Articletitled, The Effect of Glucocorticoids on the Expression of L-Selectin on Polymorphonuclear Leukocyte

TRANSPLANTATION

Graft-Versus-Leukemia Effect and Graft-Versus-Host Disease Can Be Differentiated by Cytotoxic Mechanisms in a Murine Model of Allogeneic Bone Marrow Transplantation

Nobuhiro Tsukada,Tetsuji Kobata,Yoshifusa Aizawa,Hideo Yagita,Ko Okumura

View Articletitled, Graft-Versus-Leukemia Effect and Graft-Versus-Host Disease Can Be Differentiated by Cytotoxic Mechanisms in a Murine Model of Allogeneic Bone Marrow Transplantation

CORRESPONDENCE

Chimerism Following Donor Lymphocyte Infusion for Chronic Myeloid Leukemia

Nicola Gardiner,Shaun R. McCann,Joan O’Riordan,Mark Lawler

View Articletitled, Chimerism Following Donor Lymphocyte Infusion for Chronic Myeloid Leukemia

Detection of Human Herpesvirus-8 and Epstein-Barr Virus DNA in Primary Intraocular Lymphomas

Chi-Chao Chan,De Fen Shen,Scott M. Whitcup,Robert B. Nussenblatt,Phuc LeHoang,Francois G. Roberge,Nathalie Cassoux,Carl Herbort,Zhengping Zhuang

View Articletitled, Detection of Human Herpesvirus-8 and Epstein-Barr Virus DNA in Primary Intraocular Lymphomas

ERRATA

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