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Volume 91, Issue 4

February 15 1998

In this Issue

REVIEW ARTICLES
RAPID COMMUNICATIONS
CLINICAL INTERVENTION AND THERAPEUTIC TRIALS
HEMATOPOIESIS
HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY
IMMUNOBIOLOGY
NEOPLASIA
RED CELLS
TRANSPLANTATION

Table of Contents

REVIEW ARTICLES

c-kit Ligand and Flt3 Ligand: Stem/Progenitor Cell Factors With Overlapping Yet Distinct Activities

Stewart D. Lyman,Sten Eirik W. Jacobsen

RAPID COMMUNICATIONS

A Novel Mutation of Arg306 of Factor V Gene in Hong Kong Chinese

W.P. Chan,C.K. Lee,Y.L. Kwong,C.K. Lam,Raymond Liang

Factor V Cambridge: A New Mutation (Arg³⁰⁶→Thr) Associated With Resistance to Activated Protein C

David Williamson,Karen Brown,Roger Luddington,Caroline Baglin,Trevor Baglin

De Novo CD5⁺ Diffuse Large B-Cell Lymphomas Express VH Genes With Somatic Mutation

Masanori Taniguchi,Kouji Oka,Atsunori Hiasa,Motoko Yamaguchi,Toshiyuki Ohno,Kenkichi Kita,Hiroshi Shiku

The Cytoplasmic Domain of Stem Cell Antigen CD34 Is Essential for Cytoadhesion Signaling But Not Sufficient for Proliferation Signaling

Mickey C.-T. Hu,Shu L. Chien

The Anemic Friend Virus gp55 Envelope Protein Induces Erythroid Differentiation in Fetal Liver Colony-Forming Units-Erythroid

Stefan N. Constantinescu,Hong Wu,Xuedong Liu,Wendy Beyer,Amy Fallon,Harvey F. Lodish

CLINICAL INTERVENTION AND THERAPEUTIC TRIALS

A Prospective Multicenter Study of Hepatocellular Carcinoma in Italian Hemophiliacs With Chronic Hepatitis C

F. Tradati,M. Colombo,P.M. Mannucci,M.G. Rumi,C. De Fazio,G. Gamba,N. Ciavarella,A. Rocino,M. Morfini,A. Scaraggi,E. Taioli,the Study Group of the Association of Italian Hemophilia Centers

Risk Factors, Treatment, and Outcome of Central Nervous System Recurrence in Adults With Intermediate-Grade and Immunoblastic Lymphoma

Koen van Besien,Chul S. Ha,Sandy Murphy,Peter McLaughlin,Alma Rodriguez,Kamal Amin,Arthur Forman,Jorge Romaguera,Fredrick Hagemeister,Anas Younes,Carlos Bachier,Andreas Sarris,Kathleen S. Sobocinski,James D. Cox,Fernando Cabanillas

HEMATOPOIESIS

Embryonal Carcinoma P19 Cells Produce Erythropoietin Constitutively But Express Lactate Dehydrogenase in an Oxygen-Dependent Manner

Taiho Kambe,Junko Tada,Mariko Chikuma,Seiji Masuda,Masaya Nagao,Terumasa Tsuchiya,Peter J. Ratcliffe,Ryuzo Sasaki

Transmigration of CD34⁺ Cells Across Specialized and Nonspecialized Endothelium Requires Prior Activation by Growth Factors and Is Mediated by PECAM-1 (CD31)

Kwee L. Yong,Mike Watts,N. Shaun Thomas,Angela Sullivan,Stuart Ings,David C. Linch

Thrombopoietin, kit Ligand, and flk2/flt3 Ligand Together Induce Increased Numbers of Primitive Hematopoietic Progenitors From Human CD34⁺Thy-1⁺Lin⁻ Cells With Preserved Ability to Engraft SCID-hu Bone

Karin M. Luens,Marilyn A. Travis,Ben P. Chen,Beth L. Hill,Roland Scollay,Lesley J. Murray

Stage-Specific Expression of Polycomb Group Genes in Human Bone Marrow Cells

Julie Lessard,Soheyl Baban,Guy Sauvageau

Productive Human Immunodeficiency Virus-1 Infection of Purified Megakaryocytic Progenitors/Precursors and Maturing Megakaryocytes

C. Chelucci,M. Federico,R. Guerriero,G. Mattia,I. Casella,E. Pelosi,U. Testa,G. Mariani,H.J. Hassan,C. Peschle

Fas Ligand Is Present in Human Erythroid Colony-Forming Cells and Interacts With Fas Induced by Interferon γ to Produce Erythroid Cell Apoptosis

Chun-Hua Dai,James O. Price,Thomas Brunner,Sanford B. Krantz

Engraftment and Retroviral Marking of CD34⁺ and CD34⁺CD38⁻ Human Hematopoietic Progenitors Assessed in Immune-Deficient Mice

Mo A. Dao,Ami J. Shah,Gay M. Crooks,Jan A. Nolta

Expression of Bomapin, a Novel Human Serpin, in Normal/Malignant Hematopoiesis and in the Monocytic Cell Lines THP-1 and AML-193

Matthias Riewald,Trinette Chuang,Andreas Neubauer,Hanno Riess,Raymond R. Schleef

Integrin β2 (CD18)-Mediated Cell Proliferation of HEL Cells on a Hematopoietic-Supportive Bone Marrow Stromal Cell Line, HESS-5 Cells

Takashi Tsuji,Iwao Waga,Katsunari Tezuka,Masafumi Kamada,Kimio Yatsunami,Hisashi Kodama

Isolation and Characterization of Murine Clonogenic Osteoclast Progenitors by Cell Surface Phenotype Analysis

Yukari Muguruma,Minako Y. Lee

No Neuronal Regulation of Murine Bone Marrow Function

Haakon B. Benestad,Inger Strøm-Gundersen,Per Ole Iversen,Egil Haug,Arild Njå

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

Correlation of Thrombosis With Increased Platelet Turnover in Thrombocytosis

Henry M. Rinder,Judith E. Schuster,Christine S. Rinder,Chao Wang,Helen J. Schweidler,Brian R. Smith

Human Signaling Protein 14-3-3ζ Interacts With Platelet Glycoprotein Ib Subunits Ibα and Ibβ

David C. Calverley,Terrance J. Kavanagh,Gerald J. Roth

Studies of Multimerin in Human Endothelial Cells

Catherine P. M. Hayward,Elisabeth M. Cramer,Zhili Song,Shilun Zheng,Roxanna Fung,Jean-Marc Massé,Ron H. Stead,Thomas J. Podor

Platelet-Endothelial Interactions in Inflamed Mesenteric Venules

Paul S. Frenette,Caitlin Moyna,Daqing W. Hartwell,John B. Lowe,Richard O. Hynes,Denisa D. Wagner

Screening for von Willebrand Disease With a New Analyzer Using High Shear Stress: A Study of 60 Cases

Edith Fressinaud,Agnès Veyradier,Florence Truchaud,Isabelle Martin,Catherine Boyer-Neumann,Marc Trossaert,Dominique Meyer

IMMUNOBIOLOGY

Characterization of Functional Vanilloid Receptors Expressed by Mast Cells

Tamás Bı́ró,Marcus Maurer,Shayan Modarres,Nancy E. Lewin,Chaya Brodie,Géza Ács,Péter Ács,Ralf Paus,Peter M. Blumberg

Altered Interleukin-12 Responsiveness in Th1 and Th2 Cells Is Associated With the Differential Activation of STAT5 and STAT1

Jared A. Gollob,Erin A. Murphy,Sudipta Mahajan,Claudia P. Schnipper,Jerome Ritz,David A. Frank

Interleukin-7 (IL-7) Enhances Class Switching to IgE and IgG4 in the Presence of T Cells Via IL-9 and sCD23

Pascale Jeannin,Yves Delneste,Sybille Lecoanet-Henchoz,Denise Gretener,Jean-Yves Bonnefoy

Increased Mucosal B-Lymphocyte Apoptosis During Polymicrobial Sepsis Is a Fas Ligand But Not an Endotoxin-Mediated Process

Alfred Ayala,Ying Xin Xu,Carol A. Ayala,Diane E. Sonefeld,Shannon M. Karr,Tracy A. Evans,Irshad H. Chaudry

NEOPLASIA

Epstein-Barr Virus (EBV) in Endemic Burkitt's Lymphoma: Molecular Analysis of Primary Tumor Tissue

Qian Tao,Keith D. Robertson,Angela Manns,Allan Hildesheim,Richard F. Ambinder

Detailed Molecular Delineation of 13q14.3 Loss in B-Cell Chronic Lymphocytic Leukemia

Martin M. Corcoran,Omid Rasool,Yie Liu,Arati Iyengar,Dan Grander,Rachel E. Ibbotson,Mats Merup,Xiushan Wu,Vadim Brodyansky,Anne C. Gardiner,Gunnar Juliusson,Robert M. Chapman,Ganka Ivanova,Mary Tiller,Gosta Gahrton,Nick Yankovsky,Eugene Zabarovsky,David G. Oscier,Stefan Einhorn

BCL-2 Expression Correlates With Lower Proliferative Activity in the Intermediate- and High-Grade Non-Hodgkin's Lymphomas: An Eastern Cooperative Oncology Group and Southwest Oncology Group Cooperative Laboratory Study

Jane N. Winter,Janet Andersen,John C. Reed,Stanislaw Krajewski,Daina Variakojis,Kenneth D. Bauer,Richard I. Fisher,Leo I. Gordon,Martin M. Oken,Shuwei Jiang,David Jeffries,Peter Domer

Fluorescence In Situ Hybridization Characterization of New Translocations Involving TEL (ETV6) in a Wide Spectrum of Hematologic Malignancies

Iwona Wlodarska,Roberta La Starza,Mathijs Baens,Judith Dierlamm,Ann Uyttebroeck,Dominik Selleslag,Adrien Francine,Cristina Mecucci,Anne Hagemeijer,Herman Van den Berghe,Peter Marynen

Temporal and Spatial Distribution of DNA Topoisomerase II Alters During Proliferation, Differentiation, and Apoptosis in HL-60 Cells

Koichi Sugimoto,Konagi Yamada,Motoki Egashira,Yoshio Yazaki,Hisamaru Hirai,Akihiko Kikuchi,Kazuo Oshimi

RED CELLS

The Fanconi Anemia Group C Gene Product Is Located in Both the Nucleus and Cytoplasm of Human Cells

Maureen E. Hoatlin,Tracy A. Christianson,Winnie W. Keeble,Adam T. Hammond,Yu Zhi,Michael C. Heinrich,Paula A. Tower,Grover C. Bagby Jr

Antimalarial Activity of 77 Phospholipid Polar Head Analogs: Close Correlation Between Inhibition of Phospholipid Metabolism and In Vitro Plasmodium Falciparum Growth

Marie L. Ancelin,Michèle Calas,Jacques Bompart,Gérard Cordina,Dominique Martin,Mohammed Ben Bari,Taı̈b Jei,Pierre Druilhe,Henri J. Vial

Effects of Increased Anionic Charge in the β-Globin Chain on Assembly of Hemoglobin In Vitro

Kazuhiko Adachi,Takamasa Yamaguchi,Jian Pang,Saul Surrey

HBED: A Potential Alternative to Deferoxamine for Iron-Chelating Therapy

Raymond J. Bergeron,Jan Wiegand,Gary M. Brittenham

Neonatal Hemolytic Anemia Due to Inherited Harderoporphyria: Clinical Characteristics and Molecular Basis

J. Lamoril,H. Puy,L. Gouya,R. Rosipal,V. Da Silva,B. Grandchamp,T. Foint,B. Bader-Meunier,J.P. Dommergues,J.C. Deybach,Y. Nordmann

A Novel Single Missense Mutation Identified Along the RH50 Gene in a Composite Heterozygous Rh_null Blood Donor of the Regulator Type

C.A. Hyland,B. Chérif-Zahar,N. Cowley,V. Raynal,J. Parkes,A. Saul,J.P. Cartron

TRANSPLANTATION

Soluble Fas Levels in Sera of Bone Marrow Transplantation Recipients Are Increased During Acute Graft-Versus-Host Disease But Not During Infections

Linda M. Liem,Thea van Lopik,Annemarie E.M. van Nieuwenhuijze,Hans C. van Houwelingen,Lucien Aarden,Els Goulmy

Acute Bleeding After Bone Marrow Transplantation (BMT)— Incidence and Effect on Survival. A Quantitative Analysis in 1,402 Patients

S. Nevo,V. Swan,C. Enger,K.J. Wojno,R. Bitton,M. Shabooti,A.K. Fuller,R.J. Jones,H.G. Braine,G.B. Vogelsang

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