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Volume 90, Issue 5

September 1 1997

In this Issue

REVIEW ARTICLES
RAPID COMMUNICATIONS
HEMATOPOIESIS
HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY
IMMUNOBIOLOGY
NEOPLASIA
PHAGOCYTES
RED CELLS
TRANSPLANTATION
CORRESPONDENCE
ERRATA

REVIEW ARTICLES

Molecular Biology of Fanconi Anemia: Implications for Diagnosis and Therapy

Alan D. D'Andrea,Markus Grompe

View Articletitled, Molecular Biology of Fanconi Anemia: Implications for Diagnosis and Therapy

RAPID COMMUNICATIONS

Phenotypic and Functional Analysis of Fas (CD95) Expression in Primary Central Nervous System Lymphoma of Patients With Acquired Immunodeficiency Syndrome

Robert A. Baiocchi,Vijay P. Khatri,Matthew J. Lindemann,Mary E. Ross,Giuliana Papoff,Anthony J. Caprio,Thomas V. Caprio,Robert Fenstermaker,Giovina Ruberti,Zale P. Bernstein,Michael A. Caligiuri

View Articletitled, Phenotypic and Functional Analysis of Fas (CD95) Expression in Primary Central Nervous System Lymphoma of Patients With Acquired Immunodeficiency Syndrome

A Common Prothrombin Variant (20210 G to A) Increases the Risk of Myocardial Infarction in Young Women

F.R. Rosendaal,D.S. Siscovick,S.M. Schwartz,B.M. Psaty,T.E. Raghunathan,H.L. Vos

View Articletitled, A Common Prothrombin Variant (20210 G to A) Increases the Risk of Myocardial Infarction in Young Women

Development of a Candidate HLA A*0201 Restricted Peptide-Based Vaccine Against Human Cytomegalovirus Infection

Don J. Diamond,Joanne York,Ji-Yao Sun,Christine L. Wright,Stephen J. Forman

View Articletitled, Development of a Candidate HLA A*0201 Restricted Peptide-Based Vaccine Against Human Cytomegalovirus Infection

STAT5A-Deficient Mice Demonstrate a Defect in Granulocyte-Macrophage Colony-Stimulating Factor–Induced Proliferation and Gene Expression

Gerald M. Feldman,Louis A. Rosenthal,Xiuwen Liu,Mark P. Hayes,Anthony Wynshaw-Boris,Warren J. Leonard,Lothar Hennighausen,David S. Finbloom

View Articletitled, STAT5A-Deficient Mice Demonstrate a Defect in Granulocyte-Macrophage Colony-Stimulating Factor–Induced Proliferation and Gene Expression

Retroviral-Mediated Transfer of the Green Fluorescent Protein Gene Into Murine Hematopoietic Cells Facilitates Scoring and Selection of Transduced Progenitors In Vitro and Identification of Genetically Modified Cells In Vivo

Derek A. Persons,James A. Allay,Esther R. Allay,Richard J. Smeyne,Richard A. Ashmun,Brian P. Sorrentino,Arthur W. Nienhuis

View Articletitled, Retroviral-Mediated Transfer of the Green Fluorescent Protein Gene Into Murine Hematopoietic Cells Facilitates Scoring and Selection of Transduced Progenitors In Vitro and Identification of Genetically Modified Cells In Vivo

HEMATOPOIESIS

Infection of Human Marrow Stroma by Human Immunodeficiency Virus-1 (HIV-1) Is Both Required and Sufficient for HIV-1–Induced Hematopoietic Suppression In Vitro: Demonstration by Gene Modification of Primary Human Stroma

Ingrid Bahner,Karen Kearns,Sunita Coutinho,Earl H. Leonard,Donald B. Kohn

View Articletitled, Infection of Human Marrow Stroma by Human Immunodeficiency Virus-1 (HIV-1) Is Both Required and Sufficient for HIV-1–Induced Hematopoietic Suppression In Vitro: Demonstration by Gene Modification of Primary Human Stroma

Defects in Yolk Sac Hematopoiesis in Mll-Null Embryos

Jay L. Hess,Benjamin D. Yu,Bin Li,Rob Hanson,Stanley J. Korsmeyer

View Articletitled, Defects in Yolk Sac Hematopoiesis in Mll-Null Embryos

Expression of Functional TrkA Receptor Tyrosine Kinase in the HMC-1 Human Mast Cell Line and in Human Mast Cells

See-Ying Tam,Mindy Tsai,Masao Yamaguchi,Koji Yano,Joseph H. Butterfield,Stephen J. Galli

View Articletitled, Expression of Functional TrkA Receptor Tyrosine Kinase in the HMC-1 Human Mast Cell Line and in Human Mast Cells

Regulation of the Serum Concentration of Thrombopoietin in Thrombocytopenic NF-E2 Knockout Mice

Ramesh A. Shivdasani,Paul Fielder,Gilbert-Andre Keller,Stuart H. Orkin,Frederic J. de Sauvage

View Articletitled, Regulation of the Serum Concentration of Thrombopoietin in Thrombocytopenic NF-E2 Knockout Mice

Granulocytic Differentiation of Normal Hematopoietic Precursor Cells Induced by Transcription Factor PU.1 Correlates With Negative Regulation of the c-myb Promoter

Teresa Bellon,Danilo Perrotti,Bruno Calabretta

View Articletitled, Granulocytic Differentiation of Normal Hematopoietic Precursor Cells Induced by Transcription Factor PU.1 Correlates With Negative Regulation of the c-myb Promoter

Lineage-Specific Regulation of Hematopoiesis by HOX-B8 (HOX-2.4): Inhibition of Granulocytic Differentiation and Potentiation of Monocytic Differentiation

Kandasamy Krishnaraju,Barbara Hoffman,Dan A. Liebermann

View Articletitled, Lineage-Specific Regulation of Hematopoiesis by HOX-B8 (HOX-2.4): Inhibition of Granulocytic Differentiation and Potentiation of Monocytic Differentiation

Mutations in the Murine Fitness 1 Gene Result in Defective Hematopoiesis

Mark D. Potter,Sarah G. Shinpock,Raymond A. Popp,Diana M. Popp,Virginia Godfrey,Donald A. Carpenter,Alan Bernstein,Dabney K. Johnson,Eugene M. Rinchik

View Articletitled, Mutations in the Murine Fitness 1 Gene Result in Defective Hematopoiesis

Influence of Interleukin-3 and Other Growth Factors on α₄β₁ Integrin-Mediated Adhesion and Migration of Human Hematopoietic Progenitor Cells

Karen P. Schofield,Graham Rushton,Martin J. Humphries,T. Michael Dexter,John T. Gallagher

View Articletitled, Influence of Interleukin-3 and Other Growth Factors on α4β1 Integrin-Mediated Adhesion and Migration of Human Hematopoietic Progenitor Cells

The β Chain of the Interleukin-3 Receptor Functionally Associates With the Erythropoietin Receptor

Paul T. Jubinsky,Oleg I. Krijanovski,David G. Nathan,Jan Tavernier,Colin A. Sieff

View Articletitled, The β Chain of the Interleukin-3 Receptor Functionally Associates With the Erythropoietin Receptor

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

The Suicide Substrate Reaction Between Plasminogen Activator Inhibitor 1 and Thrombin Is Regulated by the Cofactors Vitronectin and Heparin

Marja van Meijer,Annelies Smilde,Guido Tans,Michael E. Nesheim,Hans Pannekoek,Anton J.G. Horrevoets

View Articletitled, The Suicide Substrate Reaction Between Plasminogen Activator Inhibitor 1 and Thrombin Is Regulated by the Cofactors Vitronectin and Heparin

A Novel Degradation Pathway of Tissue Factor Pathway Inhibitor: Incorporation Into Fibrin Clot and Degradation by Thrombin

Naoki Ohkura,Kei-ichi Enjyoji,Yu-ichi Kamikubo,Hisao Kato

View Articletitled, A Novel Degradation Pathway of Tissue Factor Pathway Inhibitor: Incorporation Into Fibrin Clot and Degradation by Thrombin

Functional Interactions Between the Thrombin Receptor and the T-Cell Antigen Receptor in Human T-Cell Lines

David E. Joyce,Yan Chen,Rochelle A. Erger,Gary A. Koretzky,Steven R. Lentz

View Articletitled, Functional Interactions Between the Thrombin Receptor and the T-Cell Antigen Receptor in Human T-Cell Lines

Loss of Tolerance to Exogenous and Endogenous Factor VIII in a Mild Hemophilia A Patient With an Arg⁵⁹³ to Cys Mutation

Arthur R. Thompson,Michael E.P. Murphy,MiaoLiang Liu,Evgueni L. Saenko,John F. Healey,Pete Lollar,Dorothea Scandella

View Articletitled, Loss of Tolerance to Exogenous and Endogenous Factor VIII in a Mild Hemophilia A Patient With an Arg593 to Cys Mutation

IMMUNOBIOLOGY

FcγRIII-Mediated Regulation of Hematopoiesis in Murine Bone Marrow Cells by Interleukin-3 and CD95 (Fas/Apo-1)

Hideshi Yoshikawa,Toshiko Sakihama,Yasuo Nakajima,Kachio Tasaka

View Articletitled, FcγRIII-Mediated Regulation of Hematopoiesis in Murine Bone Marrow Cells by Interleukin-3 and CD95 (Fas/Apo-1)

Human Dendritic Cells Require Exogenous Interleukin-12–Inducing Factors to Direct the Development of Naive T-Helper Cells Toward the Th1 Phenotype

Catharien M.U. Hilkens,Pawel Kalinski,Mark de Boer,Martien L. Kapsenberg

View Articletitled, Human Dendritic Cells Require Exogenous Interleukin-12–Inducing Factors to Direct the Development of Naive T-Helper Cells Toward the Th1 Phenotype

CD40 Ligand Induces an Antileukemia Immune Response In Vivo

Dagmar Dilloo,Michael Brown,Marie Roskrow,Wanyung Zhong,Martha Holladay,William Holden,Malcolm Brenner

View Articletitled, CD40 Ligand Induces an Antileukemia Immune Response In Vivo

The P-Selectin Glycoprotein Ligand-1 Is Important for Recruitment of Neutrophils Into Inflamed Mouse Peritoneum

Eric Borges,Ruth Eytner,Thomas Moll,Martin Steegmaier,Matthew A. Campbell,Klaus Ley,Horst Mossmann,Dietmar Vestweber

View Articletitled, The P-Selectin Glycoprotein Ligand-1 Is Important for Recruitment of Neutrophils Into Inflamed Mouse Peritoneum

In Vitro Negative Selection of Viral Superantigen-Reactive Thymocytes by Thymic Dendritic Cells

Isabel Ferrero,Fabienne Anjuère,H. Robson MacDonald,Carlos Ardavı́n

View Articletitled, In Vitro Negative Selection of Viral Superantigen-Reactive Thymocytes by Thymic Dendritic Cells

Fas-Fas Ligand–Based Interactions Between Tumor Cells and Tumor-Specific Cytotoxic T Lymphocytes: A Lethal Two-Way Street

Ahmet Zeytun,Mona Hassuneh,Mitzi Nagarkatti,Prakash S. Nagarkatti

View Articletitled, Fas-Fas Ligand–Based Interactions Between Tumor Cells and Tumor-Specific Cytotoxic T Lymphocytes: A Lethal Two-Way Street

Myeloma Bone Marrow Plasma Cells: Evidence for Their Capacity as Antigen-Presenting Cells

Qing Yi,Sunil Dabadghao,Anders Österborg,Susanne Bergenbrant,Göran Holm

View Articletitled, Myeloma Bone Marrow Plasma Cells: Evidence for Their Capacity as Antigen-Presenting Cells

NEOPLASIA

Activity of Thymidine Kinase and of Polymerase α as Well as Activity and Gene Expression of Deoxycytidine Deaminase in Leukemic Blasts Are Correlated With Clinical Response in the Setting of Granulocyte-Macrophage Colony-Stimulating Factor–Based Priming Before and During TAD-9 Induction Therapy in Acute Myeloid Leukemia

Gerlinde Jahns-Streubel,Christoph Reuter,Ulrike Auf der Landwehr,Michael Unterhalt,Eberhard Schleyer,Bernhard Wörmann,Thomas Büchner,Wolfgang Hiddemann

View Articletitled, Activity of Thymidine Kinase and of Polymerase α as Well as Activity and Gene Expression of Deoxycytidine Deaminase in Leukemic Blasts Are Correlated With Clinical Response in the Setting of Granulocyte-Macrophage Colony-Stimulating Factor–Based Priming Before and During TAD-9 Induction Therapy in Acute Myeloid Leukemia

Seroreactivity to an Envelope Protein of Human T-Cell Leukemia/Lymphoma Virus in Patients With CD3⁻ (Natural Killer) Lymphoproliferative Disease of Granular Lymphocytes

Thomas P. Loughran, Jr,Kenneth G. Hadlock,Qing Yang,Raisa Perzova,Renato Zambello,Gianpietro Semenzato,Steven K.H. Foung,Bernard J. Poiesz

View Articletitled, Seroreactivity to an Envelope Protein of Human T-Cell Leukemia/Lymphoma Virus in Patients With CD3− (Natural Killer) Lymphoproliferative Disease of Granular Lymphocytes

MDM2 Protein Overexpression Promotes Proliferation and Survival of Multiple Myeloma Cells

Gerrard Teoh,Mitsuyoshi Urashima,Atsushi Ogata,Dharminder Chauhan,James A. DeCaprio,Steven P. Treon,Robert L. Schlossman,Kenneth C. Anderson

View Articletitled, MDM2 Protein Overexpression Promotes Proliferation and Survival of Multiple Myeloma Cells

Altered Tumor Growth and Metastasis of a T-Cell Lymphoma in Timp-1 Transgenic Mice

Achim Krüger,Jimmie E. Fata,Rama Khokha

View Articletitled, Altered Tumor Growth and Metastasis of a T-Cell Lymphoma in Timp-1 Transgenic Mice

Long-Term Malignant Hematopoiesis in Human Acute Leukemia Bone Marrow Biopsies Implanted in Severe Combined Immunodeficiency Mice

Faezeh Legrand,Ibrahim Khazaal,Michel Peuchmaur,Odile Fenneteau,Hélène Cavé,Pierre Rohrlich,Etienne Vilmer,Bruno Péault

View Articletitled, Long-Term Malignant Hematopoiesis in Human Acute Leukemia Bone Marrow Biopsies Implanted in Severe Combined Immunodeficiency Mice

Allelotype Analysis in the Evolution of Chronic Myelocytic Leukemia

Naoki Mori,Roberta Morosetti,Stephen Lee,Susanne Spira,Dina Ben-Yehuda,Gary Schiller,Raffaele Landolfi,Hideaki Mizoguchi,H. Phillip Koeffler

View Articletitled, Allelotype Analysis in the Evolution of Chronic Myelocytic Leukemia

Growth of Human T-Cell Lineage Acute Leukemia in Severe Combined Immunodeficiency (SCID) Mice and Non-obese Diabetic SCID Mice

Jeremy P.C. Steele,Robyn D. Clutterbuck,Ray L. Powles,Paul L.R. Mitchell,Clive Horton,Ricardo Morilla,Daniel Catovsky,John L. Millar

View Articletitled, Growth of Human T-Cell Lineage Acute Leukemia in Severe Combined Immunodeficiency (SCID) Mice and Non-obese Diabetic SCID Mice

Recombinant RFB4 Immunotoxins Exhibit Potent Cytotoxic Activity for CD22-Bearing Cells and Tumors

Elizabeth Mansfield,Peter Amlot,Ira Pastan,David J. FitzGerald

View Articletitled, Recombinant RFB4 Immunotoxins Exhibit Potent Cytotoxic Activity for CD22-Bearing Cells and Tumors

PHAGOCYTES

Lipoprotein(a) Is a Potent Chemoattractant for Human Peripheral Monocytes

Tatjana Syrovets,Joëlle Thillet,M. John Chapman,Thomas Simmet

View Articletitled, Lipoprotein(a) Is a Potent Chemoattractant for Human Peripheral Monocytes

RED CELLS

In Vivo Removal of Malaria Parasites From Red Blood Cells Without Their Destruction in Acute Falciparum Malaria

Brian J. Angus,Kesinee Chotivanich,Rachanee Udomsangpetch,Nicholas J. White

View Articletitled, In Vivo Removal of Malaria Parasites From Red Blood Cells Without Their Destruction in Acute Falciparum Malaria

RheothRx (Poloxamer 188) Injection for the Acute Painful Episode of Sickle Cell Disease: A Pilot Study

Patricia Adams-Graves,Amos Kedar,Mabel Koshy,Martin Steinberg,Robert Veith,Daniel Ward,Rebekah Crawford,Suzanne Edwards,James Bustrack,Martin Emanuele

View Articletitled, RheothRx (Poloxamer 188) Injection for the Acute Painful Episode of Sickle Cell Disease: A Pilot Study

Presence in Human Erythrocyte Membranes of a Novel Form of Sialidase Acting Optimally at Neutral pH

Bruno Venerando,Amelia Fiorilli,Gian Luigi Croci,Guido Tettamanti

View Articletitled, Presence in Human Erythrocyte Membranes of a Novel Form of Sialidase Acting Optimally at Neutral pH

Two New EPO Receptor Mutations: Truncated EPO Receptors Are Most Frequently Associated With Primary Familial and Congenital Polycythemias

Robert Kralovics,Karel Indrak,Tomas Stopka,Brian W. Berman,Jaroslav F. Prchal,Josef T. Prchal

View Articletitled, Two New EPO Receptor Mutations: Truncated EPO Receptors Are Most Frequently Associated With Primary Familial and Congenital Polycythemias

The Hemoglobin-Deficit Mouse: Analysis of Phenotype and Hematopoiesis in the Transplant Model

Michael L. Bloom,Karen L. Simon-Stoos

View Articletitled, The Hemoglobin-Deficit Mouse: Analysis of Phenotype and Hematopoiesis in the Transplant Model

Expression of SCL Is Normal in Transfusion-Dependent Diamond-Blackfan Anemia But Other bHLH Proteins Are Deficient

Min-Ying Zhang,Gary A. Clawson,Nancy F. Olivieri,Laurie L. Bell,C. Glenn Begley,Barbara A. Miller

View Articletitled, Expression of SCL Is Normal in Transfusion-Dependent Diamond-Blackfan Anemia But Other bHLH Proteins Are Deficient

Induction of γ-Globin by Histone Deacetylase Inhibitors

Patricia G. McCaffrey,David A. Newsome,Eitan Fibach,Minoru Yoshida,Michael S.-S. Su

View Articletitled, Induction of γ-Globin by Histone Deacetylase Inhibitors

Hereditary Hyperferritinemia-Cataract Syndrome Caused by a 29-Base Pair Deletion in the Iron Responsive Element of Ferritin L-Subunit Gene

Domenico Girelli,Roberto Corrocher,Luigi Bisceglia,Oliviero Olivieri,Leopoldo Zelante,Giacomo Panozzo,Paolo Gasparini

View Articletitled, Hereditary Hyperferritinemia-Cataract Syndrome Caused by a 29-Base Pair Deletion in the Iron Responsive Element of Ferritin L-Subunit Gene

TRANSPLANTATION

In Vitro Generation of Allospecific Human CD8⁺ T Cells of Tc1 and Tc2 Phenotype

David C. Halverson,Gretchen N. Schwartz,Charles Carter,Ronald E. Gress,Daniel H. Fowler

View Articletitled, In Vitro Generation of Allospecific Human CD8+ T Cells of Tc1 and Tc2 Phenotype

Association of Specific Cytomegalovirus Genotypes With Death From Myelosuppression After Marrow Transplantation

Beverly Torok-Storb,Michael Boeckh,Cynthia Hoy,Wendy Leisenring,David Myerson,Ted Gooley

View Articletitled, Association of Specific Cytomegalovirus Genotypes With Death From Myelosuppression After Marrow Transplantation

Bone Marrow Contains Virus-Specific Cytotoxic T Lymphocytes

Mark K. Slifka,Jason K. Whitmire,Rafi Ahmed

View Articletitled, Bone Marrow Contains Virus-Specific Cytotoxic T Lymphocytes

CORRESPONDENCE

Radiation-Induced von Willebrand Factor Release

Marcel Verheij,Luc Dewit,Jan A. Van Mourik

View Articletitled, Radiation-Induced von Willebrand Factor Release

Identity Between Hairy B-Cell Lymphoproliferative Disorder and Persistent Polyclonal B Lymphocytosis?

X. Troussard,H. Mossafa,G. Flandrin

View Articletitled, Identity Between Hairy B-Cell Lymphoproliferative Disorder and Persistent Polyclonal B Lymphocytosis?

Cloning of PAR3 cDNA From Human Platelets, and Human Erythroleukemic and Human Promonocytic Cell Lines

Timothy J. Scase,M. Fred Heath,Richard J. Evans

View Articletitled, Cloning of PAR3 cDNA From Human Platelets, and Human Erythroleukemic and Human Promonocytic Cell Lines

Should Patients With Atherosclerosis or Peripheral Vascular Disease Be Stratified for Factor V Leiden?

Craig D. Irvine,Paul W.X. Foley,Graham R. Standen,C. Morse

View Articletitled, Should Patients With Atherosclerosis or Peripheral Vascular Disease Be Stratified for Factor V Leiden?

Epstein-Barr Virus Lytic Infection in Lymphocytes and the Persistence of the Virus

Qian Tao

View Articletitled, Epstein-Barr Virus Lytic Infection in Lymphocytes and the Persistence of the Virus

Hepatitis C Virus Infection and Gastric Lymphoproliferation in Patients With Sjögren's Syndrome

D. Sorrentino,G.F. Ferraccioli,S. DeVita,A. Labombarda,M. Boiocchi,E. Bartoli

View Articletitled, Hepatitis C Virus Infection and Gastric Lymphoproliferation in Patients With Sjögren's Syndrome

Overall Survival as an Endpoint in Cutaneous T-Cell Lymphoma

Herschel S. ZackheimMD

View Articletitled, Overall Survival as an Endpoint in Cutaneous T-Cell Lymphoma

ERRATA

ERRATUM

View Articletitled, ERRATUM

ERRATUM

View Articletitled, ERRATUM

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TR4 and BCL11A Repress γ-globin Transcription via Independent Mechanisms

How I Treat Older Patients with Ph/BCR-ABL-Negative Acute Lymphoblastic Leukemia

T-Cell Lymphomas in Recipients of CAR-T Cells: Assessing Risks and Causalities

Constitutive STAT5 activation in precursor B-cell acute lymphoblastic leukemia with P2RY8::CRLF2 fusion

Genetic alteration of class I HLA in cutaneous T-cell lymphoma