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Volume 89, Issue 9

May 1 1997

In this Issue

REVIEW ARTICLES
RAPID COMMUNICATIONS
CLINICAL INTERVENTION AND THERAPEUTIC TRIALS
HEMATOPOIESIS
HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY
IMMUNOBIOLOGY
NEOPLASIA
PHAGOCYTES
RED CELLS
TRANSPLANTATION
CORRESPONDENCE
ERRATA

Table of Contents

REVIEW ARTICLES

From Malaria to Chemokine Receptor: The Emerging Physiologic Role of the Duffy Blood Group Antigen

Terence J. Hadley,Stephen C. Peiper

RAPID COMMUNICATIONS

Activation of the Stress-Activated Protein Kinases by Multiple Hematopoietic Growth Factors With the Exception of Interleukin-4

Ian N. Foltz,John W. Schrader

Deficient Activity of von Willebrand Factor–Cleaving Protease in Chronic Relapsing Thrombotic Thrombocytopenic Purpura

Miha Furlan,Rodolfo Robles,Max Solenthaler,Max Wassmer,Pierre Sandoz,Bernhard Lämmle

Lack of Expression of Thy-1 (CD90) on Acute Myeloid Leukemia Cells With Long-Term Proliferative Ability In Vitro and In Vivo

A. Blair,D.E. Hogge,L.E. Ailles,P.M. Lansdorp,H.J. Sutherland

Donor Leukocyte Infusion for Leukemic Relapse After Allogeneic Marrow Transplantation: Lack of Residual Donor Hematopoiesis Predicts Aplasia

Felix Keil,Oskar A. Haas,Gerhard Fritsch,Peter Kalhs,Klaus Lechner,Christine Mannhalter,Elisabeth Reiter,Dietger Niederwieser,Paul Hoecker,Hildegard T. Greinix

Randomized, Blinded, Placebo-Controlled Phase I Trial of Pegylated Recombinant Human Megakaryocyte Growth and Development Factor With Filgrastim After Dose-Intensive Chemotherapy in Patients With Advanced Cancer

Russell L. Basser,John E.J. Rasko,Kerrie Clarke,Jonathan Cebon,Michael D. Green,Andrew P. Grigg,John Zalcberg,Brian Cohen,Joan O'Byrne,Dora M. Menchaca,Richard M. Fox,C. Glenn Begley

CLINICAL INTERVENTION AND THERAPEUTIC TRIALS

Tumor-Specific Idiotype Vaccines in the Treatment of Patients With B-Cell Lymphoma — Long-Term Results of a Clinical Trial

Frank J. Hsu,Clemens B. Caspar,Debra Czerwinski,Larry W. Kwak,Tina Marie Liles,Athanasia Syrengelas,Behnaz Taidi-Laskowski,Ronald Levy

Recombinant Methionyl Human Stem Cell Factor and Filgrastim for Peripheral Blood Progenitor Cell Mobilization and Transplantation in Non-Hodgkin's Lymphoma Patients — Results of a Phase I/II Trial

Craig H. Moskowitz,Patrick Stiff,Michael S. Gordon,Ian McNiece,Anthony D. Ho,John J. Costa,E. Randolf Broun,Robert A. Bayer,Melody Wyres,Jerome Hill,Kathy Jelaca-Maxwell,Craig R. Nichols,Sherri L. Brown,Stephen D. Nimer,Janice Gabrilove

HEMATOPOIESIS

CIS, a Cytokine Inducible SH2 Protein, Is a Target of the JAK-STAT5 Pathway and Modulates STAT5 Activation

Akira Matsumoto,Masaaki Masuhara,Kaoru Mitsui,Masahiro Yokouchi,Motoaki Ohtsubo,Hiroyuki Misawa,Atsushi Miyajima,Akihiko Yoshimura

Expression of the Id Family Helix-Loop-Helix Regulators During Growth and Development in the Hematopoietic System

Cathleen L. Cooper,Gerard Brady,Fillio Bilia,Norman N. Iscove,Peter J. Quesenberry

Erythropoietin and Interleukin-3 Activate Tyrosine Phosphorylation of CBL and Association With CRK Adaptor Proteins

Dwayne L. Barber,Jacqueline M. Mason,Toru Fukazawa,Kris A. Reedquist,Brian J. Druker,Hamid Band,Alan D. D'Andrea

Receptors That Induce Erythroid Differentiation of Ba/F3 Cells: Structural Requirements and Effect on STAT5 Binding

Miklos Pless,Koenraad Norga,Martin Carroll,Markus H. Heim,Alan D. D'Andrea,Bernard Mathey-Prevot

Synergistic Effect of FLT-3 Ligand on the Granulocyte Colony-Stimulating Factor–Induced Mobilization of Hematopoietic Stem Cells and Progenitor Cells Into Blood in Mice

Yoshikazu Sudo,Chihiro Shimazaki,Eishi Ashihara,Takehisa Kikuta,Hideyo Hirai,Toshiya Sumikuma,Noboru Yamagata,Hideo Goto,Tohru Inaba,Naohisa Fujita,Masao Nakagawa

Strategies for Hematopoietic Stem Cell Gene Therapy: Insights From Computer Simulation Studies

Janis L. Abkowitz,Sandra N. Catlin,Peter Guttorp

The Expression of Bcl-x Is Downregulated During Differentiation of Human Hematopoietic Progenitor Cells Along the Granulocyte But Not the Monocyte/Macrophage Lineage

Cristina Sanz,Adalberto Benito,Maite Silva,Beatriz Albella,Carlos Richard,Jose Carlos Segovia,Andres Insunza,Juan Antonio Bueren,Jose Luis Fernández-Luna

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

Thiol-Disulfide Isomerization in Thrombospondin: Effects of Conformation and Protein Disulfide Isomerase

Evelyn M. Huang,Thomas C. Detwiler,Youli Milev,David W. Essex

Activation of the Coagulation Cascade in C1-Inhibitor Deficiencies

Massimo Cugno,Marco Cicardi,Bianca Bottasso,Raffaella Coppola,Raffaella Paonessa,Pier Mannuccio Mannucci,Angelo Agostoni

A Soluble Tissue Factor Mutant Is a Selective Anticoagulant and Antithrombotic Agent

Robert F. Kelley,Canio J. Refino,Mark P. O'Connell,Nishit Modi,Pat Sehl,David Lowe,Cheryl Pater,Stuart Bunting

L-Selectin–Dependent Leukocyte Adhesion to Microvascular But Not to Macrovascular Endothelial Cells of the Human Coronary System

A. Zakrzewicz,M. Gräfe,D. Terbeek,M. Bongrazio,W. Auch-Schwelk,B. Walzog,K. Graf,E. Fleck,K. Ley,P. Gaehtgens

A Histomorphometric Comparison of the Effects of Heparin and Low-Molecular-Weight Heparin on Cancellous Bone in Rats

Jeffrey M. Muir,Jack Hirsh,Jeffrey I. Weitz,Maureen Andrew,Edward Young,Stephen G. Shaughnessy

Potent Antithrombin Activity and Delayed Clearance From the Circulation Characterize Recombinant Hirudin Genetically Fused to Albumin

Summer Syed,Philip D. Schuyler,Myron Kulczycky,William P. Sheffield

Gene Cloning of Rat and Mouse Platelet Glycoprotein V: Identification of Megakaryocyte-Specific Promoters and Demonstration of Functional Thrombin Cleavage

Catherine Ravanat,Martine Morales,David O. Azorsa,Sylvie Moog,Simone Schuhler,Pierre Grunert,Damarys Loew,Alain Van Dorsselaer,Jean-Pierre Cazenave,François Lanza

A Patient With Type 2N von Willebrand Disease Is Heterozygous for a New Mutation: Gly22Glu. Demonstration of a Defective Expression of the Second Allele by the Use of Monoclonal Antibodies

J. Gu,S. Jorieux,J.M. Lavergne,C. Ruan,C. Mazurier,D. Meyer

Mechanism of Tissue Factor Activation on HL-60 Cells

Ronald R. Bach,Charles F. Moldow

IMMUNOBIOLOGY

Restricted Use of Cationic Germline V_H Gene Segments in Human Rh(D) Red Cell Antibodies

Gérard Boucher,Hervé Broly,Réal Lemieux

Thymocyte Fas Expression Is Dysregulated in Myasthenia Gravis Patients With Anti-Acetylcholine Receptor Antibody

Nathalie Moulian,Jocelyne Bidault,Frédérique Truffault,Ana Maria Yamamoto,Philippe Levasseur,Sonia Berrih-Aknin

Interleukin-4 Induces Homotypic Aggregation of Human Mast Cells by Promoting LFA-1/ICAM-1 Adhesion Molecules

Hano Toru,Tatsuo Kinashi,Chisei Ra,Shigeaki Nonoyama,Jun-ichi Yata,Tatsutoshi Nakahata

Variable Immortalizing Potential and Frequent Virus Latency in Blood-Derived T-Cell Clones Infected With Human T-Cell Leukemia Virus Type I

J.H. Richardson,P. Höllsberg,A. Windhagen,L.A. Child,D.A. Hafler,A.M.L. Lever

Cloning and Characterization of Exodus, a Novel β-Chemokine

Robert Hromas,Patrick W. Gray,David Chantry,Ronald Godiska,Mitchell Krathwohl,Kenneth Fife,Graeme I. Bell,Jun Takeda,Susan Aronica,Michael Gordon,Scott Cooper,Hal E. Broxmeyer,Michael J. Klemsz

NEOPLASIA

Acute Myeloid Leukemia in the Elderly: Assessment of Multidrug Resistance (MDR1) and Cytogenetics Distinguishes Biologic Subgroups With Remarkably Distinct Responses to Standard Chemotherapy. A Southwest Oncology Group Study

Catherine P. Leith,Kenneth J. Kopecky,John Godwin,Thomas McConnell,Marilyn L. Slovak,I-Ming Chen,David R. Head,Frederick R. Appelbaum,Cheryl L. Willman

Prognostic Value of Metaphase-Fluorescence In Situ Hybridization in Follow-up of Patients With Acute Myeloid Leukemia in Remission

Wa'el El-Rifai,Tapani Ruutu,Erkki Elonen,Liisa Volin,Sakari Knuutila

Ongoing Ig Gene Hypermutation in Salivary Gland Mucosa-Associated Lymphoid Tissue-Type Lymphomas

David W. Bahler,John A. Miklos,Steven H. Swerdlow

Use of Arsenic Trioxide (As₂O₃ ) in the Treatment of Acute Promyelocytic Leukemia (APL): I. As₂O₃ Exerts Dose-Dependent Dual Effects on APL Cells

Guo-Qiang Chen,Xue-Geng Shi,Wei Tang,Shu-Min Xiong,Jun Zhu,Xun Cai,Ze-Guang Han,Jian-Hua Ni,Gui-Ying Shi,Pei-Ming Jia,Meng-Min Liu,Kai-Li He,Chao Niu,Jun Ma,Peng Zhang,Ting-Dong Zhang,Pascale Paul,Tomoki Naoe,Kunio Kitamura,Wilson Miller,Samuel Waxman,Zhen-Yi Wang,Hugues de The,Sai-Juan Chen,Zhu Chen

Use of Arsenic Trioxide (As₂O₃ ) in the Treatment of Acute Promyelocytic Leukemia (APL): II. Clinical Efficacy and Pharmacokinetics in Relapsed Patients

Zhi-Xiang Shen,Guo-Qiang Chen,Jian-Hua Ni,Xiu-Shong Li,Shu-Min Xiong,Qian-Yao Qiu,Jun Zhu,Wei Tang,Guan-Lin Sun,Kan-Qi Yang,Yu Chen,Li Zhou,Zhi-Wen Fang,Yan-Ting Wang,Jun Ma,Peng Zhang,Ting-Dong Zhang,Sai-Juan Chen,Zhu Chen,Zhen-Yi Wang

The HRX Proto-oncogene Product Is Widely Expressed in Human Tissues and Localizes to Nuclear Structures

Lisa H. Butler,Robert Slany,Xiangmin Cui,Michael L. Cleary,David Y. Mason

Recurring Structural Chromosome Abnormalities in Peripheral Blood Lymphocytes of Patients With Mycosis Fungoides/Sézary Syndrome

Maya Thangavelu,William G. Finn,Krishna K. Yelavarthi,Henry H. Roenigk, Jr,Ellen Samuelson,LoAnn Peterson,Timothy M. Kuzel,Steven T. Rosen

Involvement of CED-3/ICE Proteases in the Apoptosis of B-Chronic Lymphocytic Leukemia Cells

Beatriz Bellosillo,Mireia Dalmau,Dolors Colomer,Joan Gil

CD24, a Mucin-Type Glycoprotein, Is a Ligand for P-Selectin on Human Tumor Cells

Silke Aigner,Zev M. Sthoeger,Mina Fogel,Erich Weber,Jürg Zarn,Michael Ruppert,Yvonka Zeller,Dietmar Vestweber,Rolf Stahel,Marei Sammar,Peter Altevogt

PHAGOCYTES

Dose-Dependent Enhancements by Interferon-γ on Functional Responses of Neutrophils From Chronic Granulomatous Disease Patients

Anders Åhlin,Göran Elinder,Jan Palmblad

The Antineoplastic Agent Bryostatin-1 Induces Proinflammatory Cytokine Production in Human Monocytes: Synergy With Interleukin-2 and Modulation of Interleukin-2Rγ Chain Expression

Maria Carla Bosco,Sandra Rottschafer,Lynn S. Taylor,John R. Ortaldo,Dan L. Longo,Igor Espinoza-Delgado

Detection and Isolation of Gene-Corrected Cells in Gaucher Disease Via a Fluorescence-Activated Cell Sorter Assay for Lysosomal Glucocerebrosidase Activity

Matthew Lorincz,Leonard A. Herzenberg,Zhenjun Diwu,John A. Barranger,William G. Kerr

Activation of the NF-κB Pathway by Inflammatory Stimuli in Human Neutrophils

Patrick P. McDonald,Anette Bald,Marco A. Cassatella

Focal Adhesion Kinase Upregulated by Granulocyte-Macrophage Colony-Stimulating Factor But Not by Interleukin-3 in Differentiating Myeloid Cells

Akihiro Kume,Hiroshi Nishiura,Junko Suda,Toshio Suda

Differential Effects of Interleukin-13 on Cytomegalovirus and Human Immunodeficiency Virus Infection in Human Alveolar Macrophages

William C. Hatch,Andrew R. Freedman,Deborah M. Boldt-Houle,Jerome E. Groopman,Ernest F. Terwilliger

RED CELLS

Abnormal Erythrocyte Endothelial Adherence in Hereditary Stomatocytosis

Brian D. Smith,George B. Segel

Phylogenetic Footprinting of Hypersensitive Site 3 of the β-Globin Locus Control Region

David A. Shelton,Lauren Stegman,Ross Hardison,Webb Miller,Jeffery H. Bock,Jerry L. Slightom,Morris Goodman,Deborah L. Gumucio

A Patient With Paroxysmal Nocturnal Hemoglobinuria Bearing Four Independent PIG-A Mutant Clones

Jun-ichi Nishimura,Norimitsu Inoue,Hiroshi Wada,Etsuko Ueda,Patcharin Pramoonjago,Toshiyuki Hirota,Takashi Machii,Takashi Kageyama,Akihisa Kanamaru,Junji Takeda,Taroh Kinoshita,Teruo Kitani

TRANSPLANTATION

The Role of B7 Costimulation by Murine Acute Myeloid Leukemia in the Generation and Function of a CD8⁺T-Cell Line With Potent In Vivo Graft-Versus-Leukemia Properties

Michael W. Boyer,Daniel A. Vallera,Patricia A. Taylor,Gary S. Gray,Emmanuel Katsanis,Keith Gorden,Paul J. Orchard,Bruce R. Blazar

CORRESPONDENCE

Wilms' Tumor Gene Expression in Human CD34⁺ Hematopoietic Progenitors During Fetal Development and Early Clonogenic Growth

Hans D. Menssen,Hans-J. Renkl,Michael Entezami,Eckhard Thiel

Delicious Poison: Arsenic Trioxide for the Treatment of Leukemia

Y.L. Kwong,D. Todd

Evidence That the Expression and Phosphorylation Status of Pleckstrin Is Modulated by Epstein-Barr Virus in Human B Lymphocytes

Norbert Kienzle,Simone Cross,David B. Young,Ihor Misko,Tom B. Sculley,Charles S. Abrams

Cytotoxic T-Lymphocyte Differentiation and Cytogenetic Alterations in γδ Hepatosplenic T-Cell Lymphoma and Posttransplant Lymphoproliferative Disorders

Kevin E. Salhany,Michael Feldman,David Peritt,Peter C. Nowell

Candida parapsilopsis Fungemias in Bone Marrow Transplant Recipients: Implications for Azole Prophylactic Therapy

J. López-Jiménez,R. Duarte-Palomino,E. Cabezudo,J.J. Velasco-Martı́nez,A. Sousa,J. Odriozola

Rapid Diagnosis of the HLA-H Gene Cys 282 Tyr Mutation in Hemochromatosis by Polymerase Chain Reaction — A Very Rare Mutation in the Chinese Population

Jan-Gowth Chang,Ta-Chih Liu,Sheng-Fung Lin

ERRATA

ERRATUM

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