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Issue Archive

Volume 89, Issue 2
January 15 1997
Blood Cover Image for Volume 89, Issue 2

Table of Contents

REVIEW ARTICLES

Activating Mutations in Cytokine Receptors: Implications for Receptor Function and Role in Disease
Thomas J. Gonda,Richard J. D'Andrea
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RAPID COMMUNICATIONS

FcγRIIA H/R131 Polymorphism, Subclass-Specific IgG Anti-Heparin/Platelet Factor 4 Antibodies and Clinical Course in Patients With Heparin-Induced Thrombocytopenia and Thrombosis
Gowthami Arepally,Steven E. McKenzie,Xiao-Ming Jiang,Mortimer Poncz,Douglas B. Cines
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Altered Myeloid Development and Acute Leukemia in Transgenic Mice Expressing PML-RARα Under Control of Cathepsin G Regulatory Sequences
Jay L. Grisolano,Robin L. Wesselschmidt,Pier Giuseppe Pelicci,Timothy J. Ley
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Differential Activation of the Tyrosine Kinases ZAP-70 and Syk After FcγRI Stimulation
Naomi Taylor,Thomas Jahn,Susan Smith,Thomas Lamkin,Lisa Uribe,Yenbou Liu,Donald L. Durden,Kenneth Weinberg
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A Single Genetic Origin for a Common Caucasian Risk Factor for Venous Thrombosis
Ariella Zivelin,John H. Griffin,Xiao Xu,Ingrid Pabinger,Michel Samama,Jacqueline Conard,Benjamin Brenner,Amiram Eldor,Uri Seligsohn
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CLINICAL INTERVENTION AND THERAPEUTIC TRIALS

A Phase-I Study of an Anti-CD25 Ricin A-Chain Immunotoxin (RFT5-SMPT-dgA) in Patients With Refractory Hodgkin's Lymphoma
Andreas Engert,Volker Diehl,Roland Schnell,Andrea Radszuhn,Maria-Theresia Hatwig,Silke Drillich,Gisela Schön,Heribert Bohlen,Hans Tesch,Martin-Leo Hansmann,Stefan Barth,John Schindler,Victor Ghetie,Jonathan Uhr,Ellen Vitetta
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Avoidance of Allogeneic Blood Transfusions by Treatment With Epoetin Beta (Recombinant Human Erythropoietin) in Patients Undergoing Open-Heart Surgery
Olaf Sowade,Harry Warnke,Paul Scigalla,Birgit Sowade,Werner Franke,Diethelm Messinger,Johann Gross
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3′-Azido 3′-Deoxythymidine + Methotrexate as a Novel Antineoplastic Combination in the Treatment of Human Immunodeficiency Virus-Related Non-Hodgkin's Lymphomas
Patrizia Tosi,Filippo Gherlinzoni,Patrizio Mazza,Giuseppe Visani,Olga Coronado,Paolo Costigliola,Enzo Raise,Magda Mazzetti,Francesco Gritti,Francesco Chiodo,Sante Tura
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HEMATOPOIESIS

The Development of Human Megakaryocytes: III. Development of Mature Megakaryocytes From Highly Purified Committed Progenitors in Synthetic Culture Media and Inhibition of Thrombopoietin-Induced Polyploidization by Interleukin-3
Alexandr Dolzhanskiy,Ross S. Basch,Simon Karpatkin
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Ectopic Expression of the Erythropoietin Receptor in a Murine Interleukin-6–Dependent Plasmacytoma Cell Line (TEPC-2027) Confers Proliferative Responsiveness to Erythropoietin
Frédéric Féger,Anne Dubart,Catherine Lacout,Isabelle Dusanter-Fourt,Patrick Mayeux,William Vainchenker,Dominique Duménil
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FLT3 Ligand Preserves the Ability of Human CD34+ Progenitors to Sustain Long-Term Hematopoiesis in Immune-Deficient Mice After Ex Vivo Retroviral-Mediated Transduction
Mo A. Dao,Charles H. Hannum,Donald B. Kohn,Jan A. Nolta
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Upregulation of Cortactin Expression During the Maturation of Megakaryocytes
Xi Zhan,Christian C. Haudenschild,Yangson Ni,Elizabeth Smith,Cai Huang
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The Unexpected G0/G1 Cell Cycle Status of Mobilized Hematopoietic Stem Cells From Peripheral Blood
Nobuko Uchida,Dongping He,Annabelle M. Friera,Michael Reitsma,Dennis Sasaki,Ben Chen,Ann Tsukamoto
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Homodimerization of Erythropoietin Receptor by a Bivalent Monoclonal Antibody Triggers Cell Proliferation and Differentiation of Erythroid Precursors
Helmut Schneider,Warak Chaovapong,David J. Matthews,Cyrus Karkaria,Robert T. Cass,Hangjun Zhan,Mark Boyle,Tony Lorenzini,Steve G. Elliott,Lutz B. Giebel
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Thrombopoietin Signal Transduction in Purified Murine Megakaryocytes
Jonathan G. Drachman,Diana F. Sabath,Norma E. Fox,Kenneth Kaushansky
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Mapping of the Active Site of Recombinant Human Erythropoietin
Steve Elliott,Tony Lorenzini,David Chang,Jack Barzilay,Evelyne Delorme
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Induction of Hypoxia-Inducible Factor-1, Erythropoietin, Vascular Endothelial Growth Factor, and Glucose Transporter-1 by Hypoxia: Evidence Against a Regulatory Role for Src Kinase
Jonathan M. Gleadle,Peter J. Ratcliffe
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Exocytotic Competence and Intergranular Fusion in Cord Blood-Derived Eosinophils During Differentiation
Susanne Scepek,Manfred Lindau
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Interactions Between c-kit and Stem Cell Factor Are Not Required for B-Cell Development In Vivo
Shunichi Takeda,Takeyuki Shimizu,Hans-Reimer Rodewald
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Tumor Necrosis Factor-α– and Interleukin-6–Triggered Mast Cell Development From Mouse Spleen Cells
Zhi-Qing Hu,Kazuo Kobayashi,Naoko Zenda,Tadakatsu Shimamura
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HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

Antithrombotic Efficacy in the Guinea Pig of a Derivative of Human Protein C With Enhanced Activation by Thrombin
Ken D. Kurz,Tommy Smith,Alexander Wilson,Bruce Gerlitz,Mark A. Richardson,Brian W. Grinnell
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Monocytes Upregulate Endothelial Cell Expression of Tissue Factor: A Role for Cell-Cell Contact and Cross-Talk
Emanuela Napoleone,Angelomaria Di Santo,Roberto Lorenzet
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IMMUNOBIOLOGY

A Cysteine Protease Inhibitor Prevents Activation-Induced T-Cell Apoptosis and Death of Peripheral Blood Cells From Human Immunodeficiency Virus-Infected Individuals by Inhibiting Upregulation of Fas Ligand
Yili Yang,Zhi-Hong Liu,Carl F. Ware,Jonathan D. Ashwell
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Differential Susceptibility to HIV-GP120–Sensitized Apoptosis in CD4+ T-Cell Clones With Different T-Helper Phenotypes: Role of CD95/CD95L Interactions
Paola Accornero,Marina Radrizzani,Domenico Delia,Franca Gerosa,Roland Kurrle,Mario P. Colombo
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Interleukin-12 (IL-12) Production in Whole Blood Cultures From Human Immunodeficiency Virus-Infected Individuals Studied in Relation to IL-10 and Prostaglandin E2 Production
Linde Meyaard,Egbert Hovenkamp,Nadine Pakker,Tineke C.T.M. van der Pouw Kraan,Frank Miedema
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The Role of Hyperuricemia in the Increased Cytokine Production After Lipopolysaccharide Challenge in Neutropenic Mice
Mihai G. Netea,Bart Jan Kullberg,Willem L. Blok,Romana T. Netea,Jos W.M. Van der Meer
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Bone Marrow and Thymus Expression of Interferon-γ Results in Severe B-Cell Lineage Reduction, T-Cell Lineage Alterations, and Hematopoietic Progenitor Deficiencies
Howard A. Young,Dennis M. Klinman,Della A. Reynolds,Krzysztof J. Grzegorzewski,Aisuke Nii,Jerrold M. Ward,Robin T. Winkler-Pickett,John R. Ortaldo,James J. Kenny,Kristin L. Komschlies
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NEOPLASIA

Frequent Jumping Translocations of Chromosomal Segments Involving the ABL Oncogene Alone or in Combination With CD3-MLL Genes in Secondary Leukemias
Kimio Tanaka,Mansyur Arif,Mariko Eguchi,Taiichi Kyo,Hiroo Dohy,Nanao Kamada
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Relationship of p53, bcl-2, and Tumor Proliferation to Clinical Drug Resistance in Non-Hodgkin's Lymphomas
Wyndham H. Wilson,Julie Teruya-Feldstein,Thierry Fest,Cynthia Harris,Seth M. Steinberg,Elaine S. Jaffe,Mark Raffeld
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Evidence for the Participation of Interleukin-2 (IL-2) and IL-4 in the Regulation of Autonomous Growth and Tumorigenesis of Transformed Cells of Lymphoid Origin
Mona R. Hassuneh,Prakash S. Nagarkatti,Mitzi Nagarkatti
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Minimally Differentiated Acute Myeloid Leukemia (AML-M0): Comparison of 25 Cases With Other French-American-British Subtypes
Adriano Venditti,Giovanni Del Poeta,Francesco Buccisano,Anna Tamburini,M. Christina Cox,Roberto Stasi,Antonio Bruno,Germano Aronica,Laura Maffei,Giovanna Suppo,Maria Domenica Simone,Laura Forte,Valeria Cordero,Massimiliano Postorino,Vincenza Tufilli,Giancarlo Isacchi,Mario Masi,Giuseppe Papa,Sergio Amadori
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Mcl-1, a Bcl-2 Family Member, Delays the Death of Hematopoietic Cells Under a Variety of Apoptosis-Inducing Conditions
Ping Zhou,Liping Qian,Karen M. Kozopas,Ruth W. Craig
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Primary Non-Hodgkin's Lymphoma of the Intestine: High Prevalence of Epstein-Barr Virus in Mexican Lymphomas as Compared With European Cases
Leticia Quintanilla-Martı́nez,Carmen Lome-Maldonado,German Ott,Andreas Gschwendtner,Evelyn Gredler,Edgardo Reyes,Arturo Angeles-Angeles,Falko Fend
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PHAGOCYTES

The Amino Terminal Lectin-Like Domain of Thrombomodulin Is Required for Constitutive Endocytosis
Edward M. Conway,Saskia Pollefeyt,Desiré Collen,Marta Steiner-Mosonyi
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Formation of Multinucleated Giant Cells In Vitro Is Dependent on the Stage of Monocyte to Macrophage Maturation
Johannes Möst,Ludwig Spötl,Gertraud Mayr,Annette Gasser,Alessandra Sarti,Manfred P. Dierich
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p15s (15-kD Antimicrobial Proteins) Are Stored in the Secondary Granules of Rabbit Granulocytes: Implications for Antibacterial Synergy With the Bactericidal/Permeability-Increasing Protein in Inflammatory Fluids
Kol Zarember,Peter Elsbach,Kwang Shin-Kim,Jerrold Weiss
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RED CELLS

Regulation of Cellular Iron Metabolism by Erythropoietin: Activation of Iron-Regulatory Protein and Upregulation of Transferrin Receptor Expression in Erythroid Cells
Günter Weiss,Tracey Houston,Stefan Kastner,Karin Jöhrer,Kurt Grünewald,Jeremy H. Brock
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Characterization of Adult α- and β-Globin Genes in the Zebrafish
Fung-Yee Chan,Judith Robinson,Alison Brownlie,Ramesh A. Shivdasani,Adriana Donovan,Carlos Brugnara,John Kim,Bing-Chuen Lau,H. Ewa Witkowska,Leonard I. Zon
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Detection of Duffy Antigen in the Plasma Membranes and Caveolae of Vascular Endothelial and Epithelial Cells of Nonerythroid Organs
Asok Chaudhuri,Søren Nielsen,Marie-Louise Elkjaer,Valerie Zbrzezna,Fang Fang,A. Oscar Pogo
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Globin Gene Switching in Transgenic Mice Carrying HS2-Globin Gene Constructs
N.A. Roberts,J.A. Sloane-Stanley,J.A. Sharpe,S.J. Stanworth,W.G. Wood
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TRANSPLANTATION

Molecular Monitoring of Minimal Residual Disease in Follicular and Mantle Cell Non-Hodgkin's Lymphomas Treated With High-Dose Chemotherapy and Peripheral Blood Progenitor Cell Autografting
Paolo Corradini,Monica Astolfi,Cristina Cherasco,Marco Ladetto,Claudia Voena,Daniele Caracciolo,Alessandro Pileri,Corrado Tarella
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CORRESPONDENCE

Milder Clinical Course of Sickle Cell Disease in Patients With α Thalassemia in the Indian Subcontinent
M.B. Mukherjee,R.B. Colah,K. Ghosh,D. Mohanty,R. Krishnamoorthy
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Developmental Outcome of Unrelated Donor Bone Marrow Transplantation in Children With Hurler Syndrome
Sean Phipps,Raymond Mulhern
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Deletion of 13q14.3 and Not 13q12 Is the Most Common Genetic Abnormality Detected in Chronic Lymphocytic Leukemia Cells
P. Panayiotidis,K. Ganeshaguru,A.V. Hoffbrand,C. Rowntree,S.A.B. Jabbar,L. Foroni
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ERRATA

ERRATUM
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ERRATUM
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