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Volume 87, Issue 12

June 15 1996

In this Issue

PHOTOGRAPHS
REVIEW
ARTICLES
MULTICENTER STUDY
LETTER

PHOTOGRAPHS

Photograph

A. M. Dvorak

View Articletitled, Photograph

REVIEW

Flow cytometry: a clinical test of platelet function

AD Michelson

View Articletitled, Flow cytometry: a clinical test of platelet function

ARTICLES

Kaposi's sarcoma-associated herpesvirus (KSHV or HHV8) in primary effusion lymphoma: ultrastructural demonstration of herpesvirus in lymphoma cells

W Said,K Chien,S Takeuchi,T Tasaka,H Asou,SK Cho,S de Vos,E Cesarman,DM Knowles,HP Koeffler

View Articletitled, Kaposi's sarcoma-associated herpesvirus (KSHV or HHV8) in primary effusion lymphoma: ultrastructural demonstration of herpesvirus in lymphoma cells

Preferential hematopoiesis by paroxysmal nocturnal hemoglobinuria clone engrafted in SCID mice

N Iwamoto,T Kawaguchi,K Horikawa,S Nagakura,T Kagimoto,T Suda,K Takatsuki,H Nakakuma

View Articletitled, Preferential hematopoiesis by paroxysmal nocturnal hemoglobinuria clone engrafted in SCID mice

Fas-mediated apoptosis of CD4+ and CD8+ T cells from human immunodeficiency virus-infected persons: differential in vitro preventive effect of cytokines and protease antagonists

J Estaquier,M Tanaka,T Suda,S Nagata,P Golstein,JC Ameisen

View Articletitled, Fas-mediated apoptosis of CD4+ and CD8+ T cells from human immunodeficiency virus-infected persons: differential in vitro preventive effect of cytokines and protease antagonists

An autosomal dominant, qualitative platelet disorder associated with multimerin deficiency, abnormalities in platelet factor V, thrombospondin, von Willebrand factor, and fibrinogen and an epinephrine aggregation defect

CP Hayward,GE Rivard,WH Kane,J Drouin,S Zheng,JC Moore,JG Kelton

View Articletitled, An autosomal dominant, qualitative platelet disorder associated with multimerin deficiency, abnormalities in platelet factor V, thrombospondin, von Willebrand factor, and fibrinogen and an epinephrine aggregation defect

Timed-sequential induction therapy improves postremission outcome in acute myeloid leukemia: a report from the Children's Cancer Group

WG Woods,N Kobrinsky,JD Buckley,JW Lee,J Sanders,S Neudorf,S Gold,DR Barnard,J DeSwarte,K Dusenbery,D Kalousek,DC Arthur,BJ Lange

View Articletitled, Timed-sequential induction therapy improves postremission outcome in acute myeloid leukemia: a report from the Children's Cancer Group

National Cancer Institute-sponsored Working Group guidelines for chronic lymphocytic leukemia: revised guidelines for diagnosis and treatment

BD Cheson,JM Bennett,M Grever,N Kay,MJ Keating,S O'Brien,KR Rai

View Articletitled, National Cancer Institute-sponsored Working Group guidelines for chronic lymphocytic leukemia: revised guidelines for diagnosis and treatment

The effect of thrombopoietin on the proliferation and differentiation of murine hematopoietic stem cells

E Sitnicka,N Lin,GV Priestley,N Fox,VC Broudy,NS Wolf,K Kaushansky

View Articletitled, The effect of thrombopoietin on the proliferation and differentiation of murine hematopoietic stem cells

Systemic hematologic effects of PEG-rHuMGDF-induced megakaryocyte hyperplasia in mice

TR Ulich,J del Castillo,G Senaldi,O Kinstler,S Yin,S Kaufman,J Tarpley,E Choi,T Kirley,P Hunt,WP Sheridan

View Articletitled, Systemic hematologic effects of PEG-rHuMGDF-induced megakaryocyte hyperplasia in mice

Ability of flt3 ligand to stimulate the in vitro growth of primitive murine hematopoietic progenitors is potently and directly inhibited by transforming growth factor-beta and tumor necrosis factor-alpha

SE Jacobsen,OP Veiby,J Myklebust,C Okkenhaug,SD Lyman

View Articletitled, Ability of flt3 ligand to stimulate the in vitro growth of primitive murine hematopoietic progenitors is potently and directly inhibited by transforming growth factor-beta and tumor necrosis factor-alpha

Morphogenesis of the bone marrow: fractal structures and diffusion- limited growth

F Naeim,F Moatamed,M Sahimi

View Articletitled, Morphogenesis of the bone marrow: fractal structures and diffusion- limited growth

Gene transfer into human bone marrow hematopoietic cells mediated by adenovirus vectors [see comments]

T Watanabe,C Kuszynski,K Ino,DG Heimann,HM Shepard,Y Yasui,DC Maneval,JE Talmadge

View Articletitled, Gene transfer into human bone marrow hematopoietic cells mediated by adenovirus vectors [see comments]

Continuous activation and deactivation of integrin CD11b/CD18 during de novo expression enables rolling neutrophils to immobilize on platelets

S Sheikh,GB Nash

View Articletitled, Continuous activation and deactivation of integrin CD11b/CD18 during de novo expression enables rolling neutrophils to immobilize on platelets

The proinflammatory cytokine response to coagulation and endotoxin in whole blood

K Johnson,L Aarden,Y Choi,E De Groot,A Creasey

View Articletitled, The proinflammatory cytokine response to coagulation and endotoxin in whole blood

Differential mechanisms targeting type 1 plasminogen activator inhibitor and vitronectin into the storage granules of a human megakaryocytic cell line

SA Hill,SG Shaughnessy,P Joshua,J Ribau,RC Austin,TJ Podor

View Articletitled, Differential mechanisms targeting type 1 plasminogen activator inhibitor and vitronectin into the storage granules of a human megakaryocytic cell line

Regulation of human heme oxygenase-1 gene expression under thermal stress

S Okinaga,K Takahashi,K Takeda,M Yoshizawa,H Fujita,H Sasaki,S Shibahara

View Articletitled, Regulation of human heme oxygenase-1 gene expression under thermal stress

A Thr359Met mutation in factor VII of a patient with a hereditary deficiency causes defective secretion of the molecule

AA Arbini,M Mannucci,KA Bauer

View Articletitled, A Thr359Met mutation in factor VII of a patient with a hereditary deficiency causes defective secretion of the molecule

Delivery of human factor IX in mice by encapsulated recombinant myoblasts: a novel approach towards allogeneic gene therapy of hemophilia B

G Hortelano,A Al-Hendy,FA Ofosu,PL Chang

View Articletitled, Delivery of human factor IX in mice by encapsulated recombinant myoblasts: a novel approach towards allogeneic gene therapy of hemophilia B

Predominant HLA-class II bound self-peptides of a hematopoietic progenitor cell line are derived from intracellular proteins

PE Harris,A Maffei,AI Colovai,J Kinne,S Tugulea,N Suciu-Foca

View Articletitled, Predominant HLA-class II bound self-peptides of a hematopoietic progenitor cell line are derived from intracellular proteins

Ecto-sialyltransferase of human B lymphocytes reconstitutes differentiation markers in the presence of exogenous CMP-N-acetyl neuraminic acid

HJ Gross,A Merling,G Moldenhauer,R Schwartz-Albiez

View Articletitled, Ecto-sialyltransferase of human B lymphocytes reconstitutes differentiation markers in the presence of exogenous CMP-N-acetyl neuraminic acid

Target cell-induced apoptosis of interleukin-2-activated human natural killer cells: roles of cell surface molecules and intracellular events

A Yamauchi,K Taga,HS Mostowski,ET Bloom

View Articletitled, Target cell-induced apoptosis of interleukin-2-activated human natural killer cells: roles of cell surface molecules and intracellular events

Involvement of nitric oxide in target-cell lysis and DNA fragmentation induced by murine natural killer cells

JG Filep,C Baron,S Lachance,C Perreault,JS Chan

View Articletitled, Involvement of nitric oxide in target-cell lysis and DNA fragmentation induced by murine natural killer cells

Release of interleukin-12 in experimental Escherichia coli septic shock in baboons: relation to plasma levels of interleukin-10 and interferon- gamma

PM Jansen,TC van der Pouw Kraan,IW de Jong,G van Mierlo,J Wijdenes,AA Chang,LA Aarden,FB Jr. Taylor,CE Hack

View Articletitled, Release of interleukin-12 in experimental Escherichia coli septic shock in baboons: relation to plasma levels of interleukin-10 and interferon- gamma

Vasoactive intestinal peptide and pituitary adenylate cyclase- activating polypeptides (PACAP27) and PACAP38) protect CD4+CD8+ thymocytes from glucocorticoid-induced apoptosis

M Delgado,E Garrido,C Martinez,J Leceta,RP Gomariz

View Articletitled, Vasoactive intestinal peptide and pituitary adenylate cyclase- activating polypeptides (PACAP27) and PACAP38) protect CD4+CD8+ thymocytes from glucocorticoid-induced apoptosis

Demonstration of functional CD40 in B-lineage acute lymphoblastic leukemia cells in response to T-cell CD40 ligand

N Renard,M Lafage-Pochitaloff,I Durand,V Duvert,L Coignet,J Banchereau,S Saeland

View Articletitled, Demonstration of functional CD40 in B-lineage acute lymphoblastic leukemia cells in response to T-cell CD40 ligand

Monoclonal Lym-1 antibody-dependent lysis of B-lymphoblastoid tumor targets by human complement and cytokinine-exposed mononuclear and neutrophilic polymorphonuclear leukocytes

L Ottonello,P Morone,P Dapino,F Dallegri

View Articletitled, Monoclonal Lym-1 antibody-dependent lysis of B-lymphoblastoid tumor targets by human complement and cytokinine-exposed mononuclear and neutrophilic polymorphonuclear leukocytes

Single human T cells stimulated in the absence of feeder cells transcribe interleukin-2 and undergo long-term clonal growth in response to defined monoclonal antibodies and cytokine stimulation

R Sunder-Plassmann,H Breiteneder,K Zimmermann,D Strunk,O Majdic,W Knapp,W Holter

View Articletitled, Single human T cells stimulated in the absence of feeder cells transcribe interleukin-2 and undergo long-term clonal growth in response to defined monoclonal antibodies and cytokine stimulation

Antiphosphatidylserine antibodies in human immunodeficiency virus-1 patients with evidence of T-cell apoptosis and mediate antibody- dependent cellular cytotoxicity [see comments]

F Silvestris,MA Frassanito,P Cafforio,D Potenza,M Di Loreto,M Tucci,MA Grizzuti,B Nico,F Dammacco

View Articletitled, Antiphosphatidylserine antibodies in human immunodeficiency virus-1 patients with evidence of T-cell apoptosis and mediate antibody- dependent cellular cytotoxicity [see comments]

CD34+CD38dim cells in the human thymus can differentiate into T, natural killer, and dendritic cells but are distinct from pluripotent stem cells

P Res,E Martinez-Caceres,A Cristina Jaleco,F Staal,E Noteboom,K Weijer,H Spits

View Articletitled, CD34+CD38dim cells in the human thymus can differentiate into T, natural killer, and dendritic cells but are distinct from pluripotent stem cells

True histiocytic lymphoma following therapy for lymphoblastic neoplasms

RA Soslow,RE Davis,RA Warnke,ML Cleary,OW Kamel

View Articletitled, True histiocytic lymphoma following therapy for lymphoblastic neoplasms

p190 BCR-ABL mRNA is expressed at low levels in p210-positive chronic myeloid and acute lymphoblastic leukemias

F van Rhee,A Hochhaus,F Lin,JV Melo,JM Goldman,NC Cross

View Articletitled, p190 BCR-ABL mRNA is expressed at low levels in p210-positive chronic myeloid and acute lymphoblastic leukemias

Linkage of a familial platelet disorder with a propensity to develop myeloid malignancies to human chromosome 21q22.1-22.2

CY Ho,B Otterud,RD Legare,T Varvil,R Saxena,DB DeHart,SE Kohler,JC Aster,SB Dowton,FP Li,M Leppert,DG Gilliland

View Articletitled, Linkage of a familial platelet disorder with a propensity to develop myeloid malignancies to human chromosome 21q22.1-22.2

Id2 expression increases with differentiation of human myeloid cells

A Ishiguro,KS Spirin,M Shiohara,A Tobler,AF Gombart,MA Israel,JD Norton,HP Koeffler

View Articletitled, Id2 expression increases with differentiation of human myeloid cells

Macrophages can recognize and kill tumor cells bearing the membrane isoform of macrophage colony-stimulating factor

MR Jadus,MC Irwin,MR Irwin,RD Horansky,S Sekhon,KA Pepper,DB Kohn,HT Wepsic

View Articletitled, Macrophages can recognize and kill tumor cells bearing the membrane isoform of macrophage colony-stimulating factor

Analysis of clonal rearrangements of the Ig heavy chain locus in acute leukemia

SE Height,GJ Swansbury,E Matutes,JG Treleaven,D Catovsky,MJ Dyer

View Articletitled, Analysis of clonal rearrangements of the Ig heavy chain locus in acute leukemia

BCL-6 expression during B-cell activation

D Allman,A Jain,A Dent,RR Maile,T Selvaggi,MR Kehry,LM Staudt

View Articletitled, BCL-6 expression during B-cell activation

DNA copy number changes in diffuse large B-cell lymphoma--comparative genomic hybridization study

O Monni,H Joensuu,K Franssila,S Knuutila

View Articletitled, DNA copy number changes in diffuse large B-cell lymphoma--comparative genomic hybridization study

Expression of Epstein-Barr virus-gene products in Burkitt's lymphoma in Northeast Brazil

I Araujo,HD Foss,A Bittencourt,M Hummel,G Demel,N Mendonca,H Herbst,H Stein

View Articletitled, Expression of Epstein-Barr virus-gene products in Burkitt's lymphoma in Northeast Brazil

Activation of MAP kinase-activated protein kinase 2 in human neutrophils after phorbol ester or fMLP peptide stimulation

YL Zu,Y Ai,A Gilchrist,ME Labadia,RI Sha'afi,CK Huang

View Articletitled, Activation of MAP kinase-activated protein kinase 2 in human neutrophils after phorbol ester or fMLP peptide stimulation

Selectins mediate eosinophil recruitment in vivo: a comparison with their role in neutrophil influx

GM Henriques,JM Miotla,SB Cordeiro,BA Wolitzky,ST Woolley,PG Hellewell

View Articletitled, Selectins mediate eosinophil recruitment in vivo: a comparison with their role in neutrophil influx

A single dose of granulocyte-macrophage colony-stimulating factor induces systemic interleukin-8 release and neutrophil activation in healthy volunteers

LJ van Pelt,MV Huisman,RS Weening,AE von dem Borne,D Roos,RH van Oers

View Articletitled, A single dose of granulocyte-macrophage colony-stimulating factor induces systemic interleukin-8 release and neutrophil activation in healthy volunteers

The stability of human beta-globin mRNA is dependent on structural determinants positioned within its 3' untranslated region

JE Russell,SA Liebhaber

View Articletitled, The stability of human beta-globin mRNA is dependent on structural determinants positioned within its 3' untranslated region

Differential use of protein 4.1 translation initiation sites during erythropoiesis: implications for a mutation-induced stage-specific deficiency of protein 4.1 during erythroid development

JA Chasis,L Coulombel,S McGee,G Lee,G Tchernia,J Conboy,N Mohandas

View Articletitled, Differential use of protein 4.1 translation initiation sites during erythropoiesis: implications for a mutation-induced stage-specific deficiency of protein 4.1 during erythroid development

The use of monoclonal antibodies and flow cytometry in the diagnosis of paroxysmal nocturnal hemoglobinuria

SE Hall,WF Rosse

View Articletitled, The use of monoclonal antibodies and flow cytometry in the diagnosis of paroxysmal nocturnal hemoglobinuria

Human herpesvirus 6: infection and disease following autologous and allogeneic bone marrow transplantation

MP Kadakia,WB Rybka,JA Stewart,JL Patton,FR Stamey,M Elsawy,PE Pellett,JA Armstrong

View Articletitled, Human herpesvirus 6: infection and disease following autologous and allogeneic bone marrow transplantation

Treatment of donor mice with an alpha beta T-cell receptor monoclonal antibody induces prolonged T-cell nonresponsiveness and effectively prevents lethal graft-versus-host disease in murine recipients of major histocompatibility complex (MHC)-matched and MHC-mismatched donor marrow grafts

WR Drobyski,D Majewski

View Articletitled, Treatment of donor mice with an alpha beta T-cell receptor monoclonal antibody induces prolonged T-cell nonresponsiveness and effectively prevents lethal graft-versus-host disease in murine recipients of major histocompatibility complex (MHC)-matched and MHC-mismatched donor marrow grafts

Individual stem cell quality in leukapheresis products is related to the number of mobilized stem cells

DA Breems,PB van Hennik,N Kusadasi,A Boudewijn,JJ Cornelissen,P Sonneveld,RE Ploemacher

View Articletitled, Individual stem cell quality in leukapheresis products is related to the number of mobilized stem cells

MULTICENTER STUDY

Inactivation of multiple tumor-suppressor genes involved in negative regulation of the cell cycle, MTS1/p16INK4A/CDKN2, MTS2/p15INK4B, p53, and Rb genes in primary lymphoid malignancies

A Hangaishi,S Ogawa,N Imamura,S Miyawaki,Y Miura,N Uike,C Shimazaki,N Emi,K Takeyama,S Hirosawa,N Kamada,Y Kobayashi,Y Takemoto,T Kitani,K Toyama,S Ohtake,Y Yazaki,R Ueda,H Hirai

View Articletitled, Inactivation of multiple tumor-suppressor genes involved in negative regulation of the cell cycle, MTS1/p16INK4A/CDKN2, MTS2/p15INK4B, p53, and Rb genes in primary lymphoid malignancies

Relationship between minimal residual disease and outcome in adult acute lymphoblastic leukemia

J Brisco,E Hughes,SH Neoh,PJ Sykes,K Bradstock,A Enno,J Szer,K McCaul,AA Morley

View Articletitled, Relationship between minimal residual disease and outcome in adult acute lymphoblastic leukemia

LETTER

Radioimmunotherapy: promising treatment of aggressive adult T-cell leukemia? [letter; comment]

H Taguchi

View Articletitled, Radioimmunotherapy: promising treatment of aggressive adult T-cell leukemia? [letter; comment]

Primary hepatosplenic lymphoma: association with hepatitis C virus infection [letter]

T Izumi,R Sasaki,Y Miura,H Okamoto

View Articletitled, Primary hepatosplenic lymphoma: association with hepatitis C virus infection [letter]

Differences in the chromosomal profile of AML-M0 versus AML-M1: response [letter; comment] [see comments]

A Cuneo,G Castoldi,JL Michaux,A Ferrant,B Chatelain,A Louwagie,AZ St Jan,M Boogaerts,PD Cin,H Van den Berghe

View Articletitled, Differences in the chromosomal profile of AML-M0 versus AML-M1: response [letter; comment] [see comments]

Thrombopoietin and its alternatively spliced form are expressed in human amygdala and hippocampus [letter]

B Li,H Pan,JC Winkelmann,W Dai

View Articletitled, Thrombopoietin and its alternatively spliced form are expressed in human amygdala and hippocampus [letter]

Interferon-alpha and hydroxyurea in early chronic myeloid leukemia: a comparative analysis of the Italian and German chronic myeloid leukemia trials with interferon-alpha [letter]

J Hasford,M Baccarani,R Hehlmann,H Anseri,S Tura,E Zuffa

View Articletitled, Interferon-alpha and hydroxyurea in early chronic myeloid leukemia: a comparative analysis of the Italian and German chronic myeloid leukemia trials with interferon-alpha [letter]

Probability calculations for a matched donor in the extended family [letter; comment]

C Kollman

View Articletitled, Probability calculations for a matched donor in the extended family [letter; comment]

Xerocytosis with concomitant intrauterine ascites: first description and therapeutic approach [letter]

M Entezami,R Becker,HD Menssen,M Marcinkowski,HT Versmold

View Articletitled, Xerocytosis with concomitant intrauterine ascites: first description and therapeutic approach [letter]

A newly discovered frameshift at codons 120-121 (+A) of the beta gene is not associated with a dominant form of beta-thalassemia [letter]

P Hopmeier,W Krugluger,LH Gu,NS Smetanina,TH Huisman

View Articletitled, A newly discovered frameshift at codons 120-121 (+A) of the beta gene is not associated with a dominant form of beta-thalassemia [letter]

bcl-2, Epstein-Barr virus-latent membrane protein, EBNA-1, and EBNA-2 staining in posttransplantation lymphoproliferative disorders [letter; comment]

R Chetty,S Biddolph,K Gatter

View Articletitled, bcl-2, Epstein-Barr virus-latent membrane protein, EBNA-1, and EBNA-2 staining in posttransplantation lymphoproliferative disorders [letter; comment]

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