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Volume 86, Issue 6

September 15 1995

In this Issue

PHOTOGRAPHS
REVIEW
ARTICLES
MULTICENTER STUDY
LETTER
ERRATUM

PHOTOGRAPHS

Photograph

A. M. Dvorak

View Articletitled, Photograph

REVIEW

Antifungal prophylaxis in patients with hematologic malignancies: a reappraisal [see comments]

O Uzun,EJ Anaissie

View Articletitled, Antifungal prophylaxis in patients with hematologic malignancies: a reappraisal [see comments]

ARTICLES

The t(10;11) translocation in acute myeloid leukemia (M5) consistently fuses the leucine zipper motif of AF10 onto the HRX gene

T Chaplin,O Bernard,HB Beverloo,V Saha,A Hagemeijer,R Berger,BD Young

View Articletitled, The t(10;11) translocation in acute myeloid leukemia (M5) consistently fuses the leucine zipper motif of AF10 onto the HRX gene

JAK3 protein tyrosine kinase mediates interleukin-7-induced activation of phosphatidylinositol-3' kinase

N Sharfe,HK Dadi,CM Roifman

View Articletitled, JAK3 protein tyrosine kinase mediates interleukin-7-induced activation of phosphatidylinositol-3' kinase

Receptor tyrosine kinase stimulates cell-matrix adhesion by phosphatidylinositol 3 kinase and phospholipase C-gamma 1 pathways

T Kinashi,JA Escobedo,LT Williams,K Takatsu,TA Springer

View Articletitled, Receptor tyrosine kinase stimulates cell-matrix adhesion by phosphatidylinositol 3 kinase and phospholipase C-gamma 1 pathways

The value of high-dose systemic chemotherapy and intrathecal therapy for central nervous system prophylaxis in different risk groups of adult acute lymphoblastic leukemia

J Cortes,SM O'Brien,S Pierce,MJ Keating,EJ Freireich,HM Kantarjian

View Articletitled, The value of high-dose systemic chemotherapy and intrathecal therapy for central nervous system prophylaxis in different risk groups of adult acute lymphoblastic leukemia

In vivo biologic effects of PIXY321, a synthetic hybrid protein of recombinant human granulocyte-macrophage colony-stimulating factor and interleukin-3 in cancer patients with normal hematopoiesis: a phase I study

S Vadhan-Raj,HE Broxmeyer,M Andreeff,JC Bandres,ES Buescher,RS Benjamin,NE Papadopoulos,A Burgess,S Patel,C Plager

View Articletitled, In vivo biologic effects of PIXY321, a synthetic hybrid protein of recombinant human granulocyte-macrophage colony-stimulating factor and interleukin-3 in cancer patients with normal hematopoiesis: a phase I study

Cytogenetic and immunologic identification of clonal expansion of stem cells into T and B lymphocytes in one Atomic-bomb survivor

Y Kusunoki,Y Kodama,Y Hirai,S Kyoizumi,N Nakamura,M Akiyama

View Articletitled, Cytogenetic and immunologic identification of clonal expansion of stem cells into T and B lymphocytes in one Atomic-bomb survivor

Molecular evidence that in situ-transduced fetal liver hematopoietic stem/progenitor cells give rise to medullary hematopoiesis in adult rats

DW Clapp,B Freie,WH Lee,YY Zhang

View Articletitled, Molecular evidence that in situ-transduced fetal liver hematopoietic stem/progenitor cells give rise to medullary hematopoiesis in adult rats

Basic fibroblast growth factor mediates its effects on committed myeloid progenitors by direct action and has no effect on hematopoietic stem cells

AC Berardi,A Wang,J Abraham,DT Scadden

View Articletitled, Basic fibroblast growth factor mediates its effects on committed myeloid progenitors by direct action and has no effect on hematopoietic stem cells

Bone marrow and splenic granulocyte-macrophage colony-stimulating factor and transforming growth factor-beta mRNA levels in irradiated mice

CM Chang,A Limanni,WH Baker,ME Dobson,JF Kalinich,W Jackson,ML Patchen

View Articletitled, Bone marrow and splenic granulocyte-macrophage colony-stimulating factor and transforming growth factor-beta mRNA levels in irradiated mice

A novel single-cell proliferation assay shows that long-term culture- initiating cell (LTC-IC) maintenance over time results from the extensive proliferation of a small fraction of LTC-IC

CM Verfaillie,JS Miller

View Articletitled, A novel single-cell proliferation assay shows that long-term culture- initiating cell (LTC-IC) maintenance over time results from the extensive proliferation of a small fraction of LTC-IC

The ski/sno protooncogene family in hematopoietic development

S Pearson-White,D Deacon,R Crittenden,G Brady,N Iscove,PJ Quesenberry

View Articletitled, The ski/sno protooncogene family in hematopoietic development

Classification of Fanconi anemia patients by complementation analysis: evidence for a fifth genetic subtype

H Joenje,JR Lo ten Foe,AB Oostra,CG van Berkel,MA Rooimans,T Schroeder- Kurth,RD Wegner,JJ Gille,M Buchwald,F Arwert

View Articletitled, Classification of Fanconi anemia patients by complementation analysis: evidence for a fifth genetic subtype

Expression and physiologic significance of Kit ligand and stem cell tyrosine kinase-1 receptor ligand in normal human CD34+, c-Kit+ marrow cells

MZ Ratajczak,WI Kuczynski,DL Sokol,JS Moore,CH Jr Pletcher,AM Gewirtz

View Articletitled, Expression and physiologic significance of Kit ligand and stem cell tyrosine kinase-1 receptor ligand in normal human CD34+, c-Kit+ marrow cells

Localization of protein disulfide isomerase to the external surface of the platelet plasma membrane

DW Essex,K Chen,M Swiatkowska

View Articletitled, Localization of protein disulfide isomerase to the external surface of the platelet plasma membrane

50-kD integrin-associated protein does not detectably influence several functions of glycoprotein IIb-IIIa complex in human platelets

T Fujimoto,K Fujimura,M Noda,T Takafuta,T Shimomura,A Kuramoto

View Articletitled, 50-kD integrin-associated protein does not detectably influence several functions of glycoprotein IIb-IIIa complex in human platelets

Immunoblot cross-reactivity of factor VIII inhibitors with porcine factor VIII

K Koshihara,J Qian,P Lollar,LW Hoyer

View Articletitled, Immunoblot cross-reactivity of factor VIII inhibitors with porcine factor VIII

Consecutive appearance of coagulation factor XIII subunit A in macrophages, megakaryocytes, and liver cells during early human development

J Kappelmayer,G Bacsko,L Birinyi,R Zakany,E Kelemen,R Adany

View Articletitled, Consecutive appearance of coagulation factor XIII subunit A in macrophages, megakaryocytes, and liver cells during early human development

Age-specific regulation of clotting factor IX gene expression in normal and transgenic mice

EJ Boland,YC Liu,CA Walter,DC Herbert,FJ Weaker,MW Odom,P Jagadeeswaran

View Articletitled, Age-specific regulation of clotting factor IX gene expression in normal and transgenic mice

Granulocyte colony-stimulating factor downregulates allogeneic immune responses by posttranscriptional inhibition of tumor necrosis factor- alpha production

A Kitabayashi,M Hirokawa,Y Hatano,M Lee,J Kuroki,H Niitsu,AB Miura

View Articletitled, Granulocyte colony-stimulating factor downregulates allogeneic immune responses by posttranscriptional inhibition of tumor necrosis factor- alpha production

Regulatory role of CD43 leukosialin on integrin-mediated T-cell adhesion to endothelial and extracellular matrix ligands and its polar redistribution to a cellular uropod

P Sanchez-Mateos,MR Campanero,MA del Pozo,F Sanchez-Madrid

View Articletitled, Regulatory role of CD43 leukosialin on integrin-mediated T-cell adhesion to endothelial and extracellular matrix ligands and its polar redistribution to a cellular uropod

Evidence for antigenic selection of large granular lymphocytes in a patient with Wiskott-Aldrich syndrome

A Sottini,A Bettinardi,E Quiros-Roldan,A Plebani,P Airo,D Primi,L Imberti

View Articletitled, Evidence for antigenic selection of large granular lymphocytes in a patient with Wiskott-Aldrich syndrome

Protease inhibitors differentially regulate tumor necrosis factor- induced apoptosis, nuclear factor-kappa B activation, cytotoxicity, and differentiation

M Higuchi,S Singh,H Chan,BB Aggarwal

View Articletitled, Protease inhibitors differentially regulate tumor necrosis factor- induced apoptosis, nuclear factor-kappa B activation, cytotoxicity, and differentiation

Calcium-dependent homotypic adhesion through leukocyte function- associated antigen-1/intracellular adhesion molecule-1 induces interleukin-1 and parathyroid hormone-related protein production on adult T-cell leukemia cells in vitro

A Wake,Y Tanaka,K Nakatsuka,M Misago,S Oda,I Morimoto,S Eto

View Articletitled, Calcium-dependent homotypic adhesion through leukocyte function- associated antigen-1/intracellular adhesion molecule-1 induces interleukin-1 and parathyroid hormone-related protein production on adult T-cell leukemia cells in vitro

Effects of iron-depletion on cell cycle progression in normal human T lymphocytes: selective inhibition of the appearance of the cyclin A- associated component of the p33cdk2 kinase

JJ Lucas,A Szepesi,J Domenico,K Takase,A Tordai,N Terada,EW Gelfand

View Articletitled, Effects of iron-depletion on cell cycle progression in normal human T lymphocytes: selective inhibition of the appearance of the cyclin A- associated component of the p33cdk2 kinase

Acquired erythropoietin responsiveness of interleukin-2-dependent T lymphocytes retrovirally transduced with genes encoding chimeric erythropoietin/interleukin-2 receptors

S Minamoto,J Treisman,WD Hankins,K Sugamura,SA Rosenberg

View Articletitled, Acquired erythropoietin responsiveness of interleukin-2-dependent T lymphocytes retrovirally transduced with genes encoding chimeric erythropoietin/interleukin-2 receptors

Evidence for a dithiol-activated signaling pathway in natural killer cell avidity regulation of leukocyte function antigen-1: structural requirements and relationship to phorbol ester- and CD16-triggered pathways

BS Edwards,MS Curry,EA Southon,AS Chong,LH Jr Graf

View Articletitled, Evidence for a dithiol-activated signaling pathway in natural killer cell avidity regulation of leukocyte function antigen-1: structural requirements and relationship to phorbol ester- and CD16-triggered pathways

Autoantibodies directed against CD43 molecules with an altered glycosylation status on human immunodeficiency virus type 1 (HIV-1)- infected CEM cells are found in all HIV-1+ individuals

V Giordanengo,M Limouse,L Desroys du Roure,J Cottalorda,A Doglio,A Passeron,JG Fuzibet,JC Lefebvre

View Articletitled, Autoantibodies directed against CD43 molecules with an altered glycosylation status on human immunodeficiency virus type 1 (HIV-1)- infected CEM cells are found in all HIV-1+ individuals

Clonal relationship between lymphocytic predominance Hodgkin's disease and concurrent or subsequent large-cell lymphoma of B lineage

RS Wickert,DD Weisenburger,A Tierens,TC Greiner,WC Chan

View Articletitled, Clonal relationship between lymphocytic predominance Hodgkin's disease and concurrent or subsequent large-cell lymphoma of B lineage

Analysis of the t(2;5)(p23;q35) translocation by reverse transcription- polymerase chain reaction in CD30+ anaplastic large-cell lymphomas, in other non-Hodgkin's lymphomas of T-cell phenotype, and in Hodgkin's disease

A Wellmann,T Otsuki,M Vogelbruch,HM Clark,ES Jaffe,M Raffeld

View Articletitled, Analysis of the t(2;5)(p23;q35) translocation by reverse transcription- polymerase chain reaction in CD30+ anaplastic large-cell lymphomas, in other non-Hodgkin's lymphomas of T-cell phenotype, and in Hodgkin's disease

Correlation of multidrug resistance (MDR1) protein expression with functional dye/drug efflux in acute myeloid leukemia by multiparameter flow cytometry: identification of discordant MDR-/efflux+ and MDR1+/efflux- cases

CP Leith,IM Chen,KJ Kopecky,FR Appelbaum,DR Head,JE Godwin,JK Weick,CL Willman

View Articletitled, Correlation of multidrug resistance (MDR1) protein expression with functional dye/drug efflux in acute myeloid leukemia by multiparameter flow cytometry: identification of discordant MDR-/efflux+ and MDR1+/efflux- cases

Hypermetaphase fluorescence in situ hybridization for quantitative monitoring of Philadelphia chromosome-positive cells in patients with chronic myelogenous leukemia during treatment

DC Seong,HM Kantarjian,JY Ro,M Talpaz,J Xu,JR Robinson,AB Deisseroth,RE Champlin,MJ Siciliano

View Articletitled, Hypermetaphase fluorescence in situ hybridization for quantitative monitoring of Philadelphia chromosome-positive cells in patients with chronic myelogenous leukemia during treatment

Tumorigenicity of human T-cell leukemia virus type I-infected cell lines in severe combined immunodeficient mice and characterization of the cells proliferating in vivo

K Imada,A Takaori-Kondo,T Akagi,K Shimotohno,K Sugamura,T Hattori,H Yamabe,M Okuma,T Uchiyama

View Articletitled, Tumorigenicity of human T-cell leukemia virus type I-infected cell lines in severe combined immunodeficient mice and characterization of the cells proliferating in vivo

TCL1 oncogene activation in preleukemic T cells from a case of ataxia- telangiectasia

MG Narducci,L Virgilio,M Isobe,A Stoppacciaro,R Elli,M Fiorilli,M Carbonari,A Antonelli,L Chessa,CM Croce,G Russo

View Articletitled, TCL1 oncogene activation in preleukemic T cells from a case of ataxia- telangiectasia

Del (7)(q32) is associated with a subset of small lymphocytic lymphoma with plasmacytoid features

K Offit,DC Louie,NZ Parsa,A Noy,RS Chaganti

View Articletitled, Del (7)(q32) is associated with a subset of small lymphocytic lymphoma with plasmacytoid features

Increase of bcr-abl chimeric mRNA expression in tumor cells of patients with chronic myeloid leukemia precedes disease progression

A Gaiger,T Henn,E Horth,K Geissler,G Mitterbauer,T Maier-Dobersberger,H Greinix,C Mannhalter,OA Haas,K Lechner

View Articletitled, Increase of bcr-abl chimeric mRNA expression in tumor cells of patients with chronic myeloid leukemia precedes disease progression

Improved transfer of the leukocyte integrin CD18 subunit into hematopoietic cell lines by using retroviral vectors having a gibbon ape leukemia virus envelope

TR Jr Bauer,AD Miller,DD Hickstein

View Articletitled, Improved transfer of the leukocyte integrin CD18 subunit into hematopoietic cell lines by using retroviral vectors having a gibbon ape leukemia virus envelope

Single-cell analysis of macrophage chemotactic protein-1-regulated cytosolic Ca2+ increase in human adherent monocytes

C Bizzarri,R Bertini,P Bossu,S Sozzani,A Mantovani,J Van Damme,A Tagliabue,D Boraschi

View Articletitled, Single-cell analysis of macrophage chemotactic protein-1-regulated cytosolic Ca2+ increase in human adherent monocytes

Specific sensitivity of CD43 to neutrophil elastase [see comments]

E Remold-O'Donnell,D Parent

View Articletitled, Specific sensitivity of CD43 to neutrophil elastase [see comments]

Neutrophil Fc gamma RIIIb deficiency, nature, and clinical consequences: a study of 21 individuals from 14 families

M de Haas,M Kleijer,R van Zwieten,D Roos,AE von dem Borne

View Articletitled, Neutrophil Fc gamma RIIIb deficiency, nature, and clinical consequences: a study of 21 individuals from 14 families

The acid deoxyribonuclease of neutrophils: a possible participant in apoptosis-associated genome destruction

RA Gottlieb,HA Giesing,RL Engler,BM Babior

View Articletitled, The acid deoxyribonuclease of neutrophils: a possible participant in apoptosis-associated genome destruction

A second generation transgenic mouse model expressing both hemoglobin S (HbS) and HbS-Antilles results in increased phenotypic severity

ME Fabry,A Sengupta,SM Suzuka,F Costantini,EM Rubin,J Hofrichter,G Christoph,E Manci,D Culberson,SM Factor

View Articletitled, A second generation transgenic mouse model expressing both hemoglobin S (HbS) and HbS-Antilles results in increased phenotypic severity

Interleukin-12 inhibits murine graft-versus-host disease

M Sykes,GL Szot,PL Nguyen,DA Pearson

View Articletitled, Interleukin-12 inhibits murine graft-versus-host disease

Protection of mice from lethal doses of methotrexate by transplantation with transgenic marrow expressing drug-resistant dihydrofolate reductase activity

C May,R Gunther,RS McIvor

View Articletitled, Protection of mice from lethal doses of methotrexate by transplantation with transgenic marrow expressing drug-resistant dihydrofolate reductase activity

MULTICENTER STUDY

Factor VIII gene inversions in severe hemophilia A: results of an international consortium study

SE Antonarakis,JP Rossiter,M Young,J Horst,P de Moerloose,SS Sommer,RP Ketterling,HH Jr Kazazian,C Negrier,C Vinciguerra

View Articletitled, Factor VIII gene inversions in severe hemophilia A: results of an international consortium study

An association between clotting factor concentrates use and mortality in human immunodeficiency virus-infected hemophilic patients

JB Montoro,J Oliveras,JI Lorenzo,JM Tusell,C Altisent,R Molina,AI Ayestaran

View Articletitled, An association between clotting factor concentrates use and mortality in human immunodeficiency virus-infected hemophilic patients

LETTER

Response to letter to editor by Bernard et al [letter; comment]

A Goldfarb

View Articletitled, Response to letter to editor by Bernard et al [letter; comment]

Novel CBF beta-MYH11 fusion transcripts and alternative splicing in acute myeloid leukemia with inversion of chromosome 16 [letter; comment] [see comments]

M Novak,K Laczika,M Mitterbauer,B Purtscher,A Scheidel-Petrovic,K Lechner,U Jaeger,OA Haas

View Articletitled, Novel CBF beta-MYH11 fusion transcripts and alternative splicing in acute myeloid leukemia with inversion of chromosome 16 [letter; comment] [see comments]

Do steady-state peripheral blood progenitor cell (PBPC) counts predict the yield of PBPC mobilized by filgrastim alone? [letter; comment]

AW Roberts,CG Begley,AP Grigg,RL Basser

View Articletitled, Do steady-state peripheral blood progenitor cell (PBPC) counts predict the yield of PBPC mobilized by filgrastim alone? [letter; comment]

Expression of HLA-DR (major histocompatibility complex class II) on neutrophils from patients treated with granulocyte-macrophage colony- stimulating factor for mobilization of stem cells [letter]

SP Mudzinski,TP Christian,TL Guo,E Cirenza,KR Hazlett,EJ Gosselin

View Articletitled, Expression of HLA-DR (major histocompatibility complex class II) on neutrophils from patients treated with granulocyte-macrophage colony- stimulating factor for mobilization of stem cells [letter]

Detection of minimal residual disease in acute leukemia [letter; comment]

R Seshadri

View Articletitled, Detection of minimal residual disease in acute leukemia [letter; comment]

ERRATUM

von Willebrand disease in the RIIIS/J mouse is caused by a defect outside of the von Willebrand factor gene

WC Nichols,KA Cooney,KL Mohlke,JD Ballew,A Yang,ME Bruck,M Reddington,EK Novak,RT Swank,D Ginsburg

View Articletitled, von Willebrand disease in the RIIIS/J mouse is caused by a defect outside of the von Willebrand factor gene

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ARTICLES

MULTICENTER STUDY

LETTER

ERRATUM

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