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Volume 86, Issue 5

September 1 1995

In this Issue

REVIEW
ARTICLES
MULTICENTER STUDY
PHOTOGRAPHS
LETTER
ERRATUM

Table of Contents

REVIEW

Chemoattractant signaling and leukocyte activation

GM Bokoch

ARTICLES

Multi-level effects of flt3 ligand on human hematopoiesis: expansion of putative stem cells and proliferation of granulomonocytic progenitors/monocytic precursors

M Gabbianelli,E Pelosi,E Montesoro,M Valtieri,L Luchetti,P Samoggia,L Vitelli,T Barberi,U Testa,S Lyman

Receptors for interleukin-3 (IL-3) and growth hormone mediate an IL-6- type transcriptional induction in the presence of JAK2 or STAT3

Y Wang,KK Morella,J Ripperger,CF Lai,DP Gearing,GH Fey,SP Campos,H Baumann

Human allogeneic stem cell maintenance and differentiation in a long- term multilineage SCID-hu graft

CC Fraser,H Kaneshima,G Hansteen,M Kilpatrick,R Hoffman,BP Chen

ALK gene products in anaplastic large cell lymphomas and Hodgkin's disease

H Herbst,J Anagnostopoulos,B Heinze,H Durkop,M Hummel,H Stein

Human Rh D monoclonal antibodies (BRAD-3 and BRAD-5) cause accelerated clearance of Rh D+ red blood cells and suppression of Rh D immunization in Rh D- volunteers

BM Kumpel,MJ Goodrick,DH Pamphilon,ID Fraser,GD Poole,C Morse,GR Standen,GE Chapman,DP Thomas,DJ Anstee

2-Chlorodeoxyadenosine activity in patients with untreated, indolent non-Hodgkin's lymphoma

A Saven,S Emanuele,M Kosty,J Koziol,D Ellison,L Piro

Early CD34high cells can be separated into KIThigh cells in which transforming growth factor-beta (TGF-beta) downmodulates c-kit and KITlow cells in which anti-TGF-beta upmodulates c-kit

P Sansilvestri,AA Cardoso,P Batard,B Panterne,A Hatzfeld,B Lim,JP Levesque,MN Monier,J Hatzfeld

Somatic mutations of PIG-A in Thai patients with paroxysmal nocturnal hemoglobinuria

P Pramoonjago,W Wanachiwanawin,S Chinprasertsak,K Pattanapanayasat,J Takeda,T Kinoshita

Collagen type VI in the human bone marrow microenvironment: a strong cytoadhesive component

G Klein,CA Muller,E Tillet,ML Chu,R Timpl

CD34+ progenitor cells from asymptomatic patients are not a major reservoir for human immunodeficiency virus-1

TF Neal,HK Holland,CM Baum,F Villinger,AA Ansari,R Saral,JR Wingard,WH Fleming

Steel factor (c-kit ligand) promotes the survival of hematopoietic stem/progenitor cells in the absence of cell division

JR Keller,M Ortiz,FW Ruscetti

Thrombocytopenia in dogs induced by granulocyte-macrophage colony- stimulating factor: increased destruction of circulating platelets

RA Nash,SA Burstein,R Storb,W Yang,K Abrams,FR Appelbaum,T Boone,HJ Deeg,LD Durack,FG Schuening

Regulation of colony-stimulating factor 1-induced proliferation by heterotrimeric Gi2 proteins

I Corre,S Hermouet

Long-term culture-initiating cell expansion is dependent on frequent medium exchange combined with stromal and other accessory cell effects

MR Koller,MA Palsson,I Manchel,BO Palsson

Factors IXa and Xa play distinct roles in tissue factor-dependent initiation of coagulation

M Hoffman,DM Monroe,JA Oliver,HR Roberts

Cell proliferation on fibrin: modulation by fibrinopeptide cleavage

LA Sporn,LA Bunce,CW Francis

Some factor VIII inhibitor antibodies recognize a common epitope corresponding to C2 domain amino acids 2248 through 2312, which overlap a phospholipid-binding site

D Scandella,GE Gilbert,M Shima,H Nakai,C Eagleson,M Felch,R Prescott,KJ Rajalakshmi,LW Hoyer,E Saenko

Factor VNew Brunswick: Ala221-to-Val substitution results in reduced cofactor activity

JM Murray,MD Rand,JO Egan,S Murphy,HC Kim,KG Mann

Endothelial-specific gene expression directed by the tie gene promoter in vivo

J Korhonen,I Lahtinen,M Halmekyto,L Alhonen,J Janne,D Dumont,K Alitalo

Both tumor necrosis factor receptors, TNFR60 and TNFR80, are involved in signaling endothelial tissue factor expression by juxtacrine tumor necrosis factor alpha

EF Schmid,K Binder,M Grell,P Scheurich,K Pfizenmaier

Isolation of human T-cell leukemia virus type I from a transformed T- cell line derived spontaneously from lymphocytes of a seronegative Egyptian patient with mycosis fungoides

MA el-Farrash,HA Salem,MJ Kuroda,K Morizono,M Kannagi,S Harada

T-cell lineage commitment and cytokine responses of thymic progenitors

TA Moore,A Zlotnik

B-cell homotypic adhesion through exon-A restricted epitopes of CD45 involves LFA-1/ICAM-1, ICAM-3 interactions, and induces coclustering of CD45 and LFA-1

JM Zapata,MR Campanero,M Marazuela,F Sanchez-Madrid,MO de Landazuri

Myb binding sites mediate negative regulation of c-myb expression in T- cell lines

J Guerra,DA Withers,LM Boxer

Acute lymphoblastic leukemias with deletion of 11q23 or a novel inversion (11)(p13q23) lack MLL gene rearrangements and have favorable clinical features

SC Raimondi,JL Frestedt,CH Pui,JR Downing,DR Head,JH Kersey,FG Behm

Hepatitis C virus within a malignant lymphoma lesion in the course of type II mixed cryoglobulinemia

S De Vita,D Sansonno,R Dolcetti,G Ferraccioli,A Carbone,V Cornacchiulo,G Santini,M Crovatto,A Gloghini,F Dammacco

BHRF1, the Epstein-Barr virus (EBV) homologue of the BCL-2 protooncogene, is transcribed in EBV-associated B-cell lymphomas and in reactive lymphocytes

JJ Oudejans,AJ van den Brule,NM Jiwa,PC de Bruin,GJ Ossenkoppele,P van der Valk,JM Walboomers,CJ Meijer

Expression of bcl-xL can confer a multidrug resistance phenotype

AJ Minn,CM Rudin,LH Boise,CB Thompson

13q deletions in lymphoid malignancies

Y Liu,M Hermanson,D Grander,M Merup,X Wu,M Heyman,O Rasool,G Juliusson,G Gahrton,R Detlofsson

The receptor tyrosine kinase p185HER2 is expressed on a subset of B- lymphoid blasts from patients with acute lymphoblastic leukemia and chronic myelogenous leukemia

HJ Buhring,I Sures,B Jallal,FU Weiss,FW Busch,WD Ludwig,R Handgretinger,HD Waller,A Ullrich

Alterations of the p27KIP1 gene in non-Hodgkin's lymphomas and adult T- cell leukemia/lymphoma

R Morosetti,N Kawamata,AF Gombart,CW Miller,Y Hatta,T Hirama,JW Said,M Tomonaga,HP Koeffler

Refined mapping of genomic rearrangements involving the short arm of chromosome 9 in acute lymphoblastic leukemias and other hematologic malignancies

MH Dreyling,SK Bohlander,MM Le Beau,OI Olopade

Expression of Fas/Apo-1 (CD95) and apoptosis in tumor cells from patients with plasma cell disorders

H Hata,H Matsuzaki,M Takeya,M Yoshida,T Sonoki,A Nagasaki,N Kuribayashi,F Kawano,K Takatsuki

Antibodies to CD40 prevent Epstein-Barr virus-mediated human B-cell lymphomagenesis in severe combined immune deficient mice given human peripheral blood lymphocytes

WJ Murphy,S Funakoshi,M Beckwith,SE Rushing,DK Conley,RJ Armitage,WC Fanslow,HC Rager,DD Taub,FW Ruscetti

Anaplastic large cell lymphomas expressing the novel chimeric protein p80NPM/ALK: a distinct clinicopathologic entity

M Shiota,S Nakamura,R Ichinohasama,M Abe,T Akagi,M Takeshita,N Mori,J Fujimoto,J Miyauchi,A Mikata

Leukemia inhibitory factor induces interleukin-8 and monocyte chemotactic and activating factor in human monocytes: differential regulation by interferon-gamma

T Musso,R Badolato,DL Longo,GL Gusella,L Varesio

Stem cell factor contributes to intestinal mucosal mast cell hyperplasia in rats infected with Nippostrongylus brasiliensis or Trichinella spiralis, but anti-stem cell factor treatment decreases parasite egg production during N brasiliensis infection

GF Newlands,HR Miller,A MacKellar,SJ Galli

Severe hemolytic anemia associated with the homozygous state for an unstable hemoglobin variant (Hb Bushwick)

P Srivastava,JS Kaeda,D Roper,TJ Vulliamy,M Buckley,L Luzzatto

The complex of phosphatidylinositol 4,5-bisphosphate and calcium ions is not responsible for Ca(2+)-induced loss of phospholipid asymmetry in the human erythrocyte: a study in Scott syndrome, a disorder of calcium- induced phospholipid scrambling

EM Bevers,T Wiedmer,P Comfurius,J Zhao,EF Smeets,RA Schlegel,AJ Schroit,HJ Weiss,P Williamson,RF Zwaal

Membrane protein interactions in sickle red blood cells: evidence of abnormal protein 3 function

OS Platt,JF Falcone

Inhibition of deoxygenation-induced membrane protein dephosphorylation and cell dehydration by phorbol esters and okadaic acid in sickle cells

H Fathallah,E Coezy,RS de Neef,MD Hardy-Dessources,F Giraud

Deferiprone (L1) chelates pathologic iron deposits from membranes of intact thalassemic and sickle red blood cells both in vitro and in vivo

O Shalev,T Repka,A Goldfarb,L Grinberg,A Abrahamov,NF Olivieri,EA Rachmilewitz,RP Hebbel

Role of hemichrome binding to erythrocyte membrane in the generation of band-3 alterations in beta-thalassemia intermedia erythrocytes

F Mannu,P Arese,MD Cappellini,G Fiorelli,M Cappadoro,G Giribaldi,F Turrini

Prevalence of heterozygotes for hemochromatosis in the white population of the United States

CE McLaren,VR Gordeuk,AC Looker,V Hasselblad,CQ Edwards,LM Griffen,JP Kushner,GM Brittenham

A retrospective analysis of the long-term effect of splenectomy on late infections, graft-versus-host disease, relapse, and survival after allogeneic marrow transplantation for chronic myelogenous leukemia

P Kalhs,I Schwarzinger,G Anderson,M Mori,RA Clift,R Storb,CD Buckner,FR Appelbaum,JA Hansen,KM Sullivan

Syngeneic bone marrow transplantation reduces the hearing loss associated with murine mucopolysaccharidosis type VII

MS Sands,LC Erway,C Vogler,WS Sly,EH Birkenmeier

Graft-versus-leukemia effect of donor lymphocyte transfusions in marrow grafted patients. European Group for Blood and Marrow Transplantation Working Party Chronic Leukemia [see comments]

HJ Kolb,A Schattenberg,JM Goldman,B Hertenstein,N Jacobsen,W Arcese,P Ljungman,A Ferrant,L Verdonck,D Niederwieser

MULTICENTER STUDY

Effect of aggressive daunomycin therapy on survival in acute promyelocytic leukemia

D Head,KJ Kopecky,J Weick,JC Files,D Ryan,K Foucar,M Montiel,J Bickers,A Fishleder,M Miller

PHOTOGRAPHS

Photograph

A. M. Dvorak

LETTER

Proposal for a classification of the clinical stages of paroxysmal nocturnal hemoglobinuria [letter]

H Nakakuma,T Kawaguchi,K Horikawa,M Hidaka,S Nagakura,N Iwamoto,T Kagimoto,K Takatsuki

Rapid and sustained allogeneic transplantation using immunoselected CD34(+)-selected peripheral blood progenitor cells mobilized by recombinant granulocyte- and granulocyte-macrophage colony-stimulating factors [letter]

RE Corringham,AD Ho

Bell's palsy as a sign of Burkitt's lymphoma in children [letter]

J Katz,A Polliack,I Harushouski,R Ben Oliel,Y Marmary

HLA-DR frequency in Turkish aplastic anemia patients and the impact of HLA-DR2 positivity in response rate in patients receiving immunosuppressive therapy [letter]

O Ilhan,M Beksac,H Koc,H Akan,A Keskin,O Arslan,G Gurman,M Ozcan,N Konuk,A Uysal

In vitro expression of the --87 beta-globin thalassemic mutations [letter]

MS Ristaldi,A Cao,S Casula

ERRATUM

Erratum for vol. 85, p. 2315

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