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Volume 86, Issue 1

July 1 1995

In this Issue

REVIEW
ARTICLES
PHOTOGRAPHS
MULTICENTER STUDY
LETTER
ERRATUM

Table of Contents

REVIEW

AML1 and the 8;21 and 3;21 translocations in acute and chronic myeloid leukemia

G Nucifora,JD Rowley

ARTICLES

Primary familial polycythemia: a frameshift mutation in the erythropoietin receptor gene and increased sensitivity of erythroid progenitors to erythropoietin

L Sokol,M Luhovy,Y Guan,JF Prchal,GL Semenza,JT Prchal

Recombinant thrombopoietin induces rapid protein tyrosine phosphorylation of Janus kinase 2 and Shc in human blood platelets

Y Miyakawa,A Oda,BJ Druker,T Kato,H Miyazaki,M Handa,Y Ikeda

BCL-6 gene product, a 92- to 98-kD nuclear phosphoprotein, is highly expressed in germinal center B cells and their neoplastic counterparts

T Onizuka,M Moriyama,T Yamochi,T Kuroda,A Kazama,N Kanazawa,K Sato,T Kato,H Ota,S Mori

Frequent loss of heterozygosity at the TEL gene locus in acute lymphoblastic leukemia of childhood

K Stegmaier,S Pendse,GF Barker,P Bray-Ward,DC Ward,KT Montgomery,KS Krauter,C Reynolds,J Sklar,M Donnelly

BCL-6 protein is expressed in germinal-center B cells

G Cattoretti,CC Chang,K Cechova,J Zhang,BH Ye,B Falini,DC Louie,K Offit,RS Chaganti,R Dalla-Favera

Recombinant human megakaryocyte growth and development factor stimulates thrombocytopoiesis in normal nonhuman primates

AM Farese,P Hunt,T Boone,TJ MacVittie

Characterization of Thy-1 (CDw90) expression in CD34+ acute leukemia

JT Holden,RB Geller,DC Farhi,HK Holland,LL Stempora,CN Phillips,RA Bray

Granulocyte-macrophage colony-stimulating factor is not responsible for the correction of hematopoietic deficiencies in the maturing op/op mouse

SK Nilsson,GJ Lieschke,CC Garcia-Wijnen,B Williams,D Tzelepis,G Hodgson,D Grail,AR Dunn,I Bertoncello

Accelerated cell-cycling of hematopoietic progenitor cells by growth factors

R Tanaka,N Katayama,K Ohishi,N Mahmud,R Itoh,Y Tanaka,Y Komada,N Minami,M Sakurai,S Shirakawa

Human interleukin-3 receptor modulates bcl-2 mRNA and protein levels through protein kinase C in TF-1 cells

MS Rinaudo,K Su,LA Falk,S Halder,RA Mufson

The severe combined immunodeficient-human peripheral blood stem cell (SCID-huPBSC) mouse: a xenotransplant model for huPBSC-initiated hematopoiesis

SR Goan,I Fichtner,U Just,L Karawajew,W Schultze,KP Krause,S von Harsdorf,C von Schilling,F Herrmann

Analysis of optimal conditions for retroviral-mediated transduction of primitive human hematopoietic cells

JA Nolta,EM Smogorzewska,DB Kohn

Efficient expression of functional human MDR1 gene in murine bone marrow after retroviral transduction of purified hematopoietic stem cells

T Licht,I Aksentijevich,MM Gottesman,I Pastan

Variations in radiation sensitivity and repair among different hematopoietic stem cell subsets following fractionated irradiation

JD Down,A Boudewijn,R van Os,HD Thames,RE Ploemacher

Interleukin-11 stimulates multilineage progenitors, but not stem cells, in murine and human long-term marrow cultures

XX Du,D Scott,ZX Yang,R Cooper,XL Xiao,DA Williams

Murine granulocytic cell adhesion to bone marrow hemonectin is mediated by mannose and galactose

BA Sullenbarger,MS Petitt,P Chong,MW Long,MS Wicha

Growth factors and stromal support generate very efficient retroviral transduction of peripheral blood CD34+ cells from Gaucher patients

LC Xu,S Kluepfel-Stahl,M Blanco,R Schiffmann,C Dunbar,S Karlsson

The human leukocyte integrin CD11a promoter directs expression in leukocytes of transgenic mice

KA Ritchie,A Aprikian,KA Gollahon,DD Hickstein

Initiation of hematopoiesis and vasculogenesis in murine yolk sac explants

J Palis,KE McGrath,PD Kingsley

Coordinate expression and developmental role of Id2 protein and TAL1/E2A heterodimer in erythroid progenitor differentiation

G Condorelli,L Vitelli,M Valtieri,I Marta,E Montesoro,V Lulli,R Baer,C Peschle

Interferon-gamma upregulates interleukin-3 (IL-3) receptor expression in human endothelial cells and synergizes with IL-3 in stimulating major histocompatibility complex class II expression and cytokine production

EI Korpelainen,JR Gamble,WB Smith,M Dottore,MA Vadas,AF Lopez

Circulation of human hematopoietic cells in severe combined immunodeficient mice after Cl2MDP-liposome-mediated macrophage depletion

CC Fraser,BP Chen,S Webb,N van Rooijen,G Kraal

Sphingosine-1-phosphate: a platelet-activating sphingolipid released from agonist-stimulated human platelets

Y Yatomi,F Ruan,S Hakomori,Y Igarashi

Enzyme-linked immunoabsorbent assay detection of a soluble form of urokinase plasminogen activator receptor in vivo

IF Mizukami,NE Faulkner,MR Gyetko,RG Sitrin,RF 3rd Todd

Retinoic acid reduces induction of monocyte tissue factor and tissue factor/factor VIIa-dependent arterial thrombus formation

RM Barstad,MJ Hamers,RW Stephens,KS Sakariassen

Incidence of activated protein C resistance caused by the ARG 506 GLN mutation in factor V in 113 unrelated symptomatic protein C-deficient patients. The French Network on the behalf of INSERM

S Gandrille,JS Greengard,M Alhenc-Gelas,I Juhan-Vague,JF Abgrall,B Jude,JH Griffin,M Aiach

The epidermal growth factor-like domain of recombinant human thrombomodulin exhibits mitogenic activity for Swiss 3T3 cells

H Hamada,H Ishii,K Sakyo,S Horie,K Nishiki,M Kazama

The impact of three-dimensional structure on the expression of PlA alloantigens on human integrin beta 3

S Honda,Y Honda,B Bauer,C Ruan,TJ Kunicki

Serum levels of stem cell factor are increased in asymptomatic human immunodeficiency virus-infected patients and are associated with prolonged survival

C Manegold,H Jablonowski,C Armbrecht,G Strohmeyer,T Pietsch

Th1 and Th2 T-helper cells exert opposite regulatory effects on procoagulant activity and tissue factor production by human monocytes

G Del Prete,M De Carli,RM Lammel,MM D'Elios,KC Daniel,B Giusti,R Abbate,S Romagnani

Increased levels of oxidized glutathione in CD4+ lymphocytes associated with disturbed intracellular redox balance in human immunodeficiency virus type 1 infection

P Aukrust,AM Svardal,F Muller,B Lunden,RK Berge,PM Ueland,SS Froland

Apoptosis in bone marrow biopsy samples involving stromal and hematopoietic cells in 50 patients with myelodysplastic syndromes [see comments]

A Raza,S Gezer,S Mundle,XZ Gao,S Alvi,R Borok,S Rifkin,A Iftikhar,V Shetty,A Parcharidou

RT-PCR diagnosis of patients with acute nonlymphocytic leukemia and inv(16)(p13q22) and identification of new alternative splicing in CBFB- MYH11 transcripts

BA van der Reijden,M Lombardo,HG Dauwerse,RH Giles,D Muhlematter,MJ Bellomo,HW Wessels,GC Beverstock,GJ van Ommen,A Hagemeijer

Identification of B-cell growth factors (interleukin-14; high molecular weight-B-cell growth factors) in effusion fluids from patients with aggressive B-cell lymphomas

R Ford,A Tamayo,B Martin,K Niu,K Claypool,F Cabanillas,J Jr Ambrus

Overexpression of cyclin D1 in the Dami megakaryocytic cell line causes growth arrest

CC Wilhide,C Van Dang,J Dipersio,AA Kenedy,PF Bray

Cutaneous T-cell infiltrates: analysis of T-cell receptor gamma gene rearrangement by polymerase chain reaction and denaturing gradient gel electrophoresis

I Theodorou,MH Delfau-Larue,C Bigorgne,C Lahet,G Cochet,M Bagot,J Wechsler,JP Farcet

p16INK4A and p15INK4B gene deletions in primary leukemias

MA Haidar,XB Cao,T Manshouri,LL Chan,A Glassman,HM Kantarjian,MJ Keating,MS Beran,M Albitar

Magnetic resonance imaging of femoral marrow in patients with myelodysplastic syndromes or leukemia

S Takagi,O Tanaka,Y Miura

Constitutive expression of GATA-1, EPOR, alpha-globin, and gamma-globin genes in myeloid clonogenic cells from juvenile chronic myelocytic leukemia

E Privitera,R Schiro,D Longoni,A Ronchi,A Rambaldi,S Bernasconi,S Ottolenghi,G Masera,A Biondi

AG dinucleotide insertion in a patient with chronic granulomatous disease lacking cytosolic 67-kD protein

H Nunoi,M Iwata,S Tatsuzawa,Y Onoe,S Shimizu,S Kanegasaki,I Matsuda

Generation of normal human red cell volume, hemoglobin content, and membrane area distributions by "birth" or regulation?

VL Lew,JE Raftos,M Sorette,RM Bookchin,N Mohandas

Perturbation of red blood cell membrane rigidity by extracellular ligands

M Paulitschke,GB Nash,DJ Anstee,MJ Tanner,WB Gratzer

Molecular basis of altered red blood cell membrane properties in Southeast Asian ovalocytosis: role of the mutant band 3 protein in band 3 oligomerization and retention by the membrane skeleton

SC Liu,J Palek,SJ Yi,PE Nichols,LH Derick,SS Chiou,D Amato,JD Corbett,MR Cho,DE Golan

cDNA structure, tissue-specific expression, and chromosomal localization of the murine band 7.2b gene

PG Gallagher,M Romana,JH Lieman,DC Ward

Hemoglobin-spectrin complexes: interference with spectrin tetramer assembly as a mechanism for compartmentalization of band 1 and band 2 complexes

CR Kiefer,JF Trainor,JB McKenney,CR Valeri,LM Snyder

Collection and transplantation of peripheral blood stem cells in very small children weighting 20 kg or less

Y Takaue,Y Kawano,T Abe,Y Okamoto,T Suzue,T Shimizu,S Saito,J Sato,A Makimoto,R Nakagawa

Purified CD34+ Lin- Thy+ stem cells do not contain clonal myeloma cells

Y Gazitt,CC Reading,R Hoffman,A Wickrema,DH Vesole,S Jagannath,J Condino,B Lee,B Barlogie,G Tricot

Human/mouse radiation chimera are capable of mounting a human primary humoral response

H Marcus,M David,A Canaan,L Kulova,I Lubin,H Segall,L Denes,P Erlich,E Galun,J Gan

PHOTOGRAPHS

Photograph

A. M. Dvorak

MULTICENTER STUDY

Transplantation of CD34+ peripheral blood progenitor cells after high- dose chemotherapy for patients with advanced multiple myeloma

G Schiller,R Vescio,C Freytes,G Spitzer,F Sahebi,M Lee,CH Wu,J Cao,JC Lee,CH Hong

LETTER

Bicentric origin of sickle hemoglobin among the inhabitants of Mauritius Island [letter]

N Kotea,S Baligadoo,S Surran,R Ramasawmy,CY Lu,R Ducrocq,D Labie,R Krishnamoorthy,R Nagel

Neurologic complications after bone marrow transplantation for sickle cell anemia [letter; comment]

A Ferster,C Christophe,B Dan,C Devalck,E Sariban

Wider benefits of leukodepletion of blood products [letter]

JA Copplestone,P Williamson,DR Norfolk,GR Morgenstern,JZ Wimperis,LM Williamson

Parvovirus B19 induced red blood cell aplasia in a patient with hereditary pyropoikilocytosis [letter]

EA Lowenthal,JT Prchal

Recombination activating gene-expression in lymphoma cell lines and lymphomas [letter; comment]

H Knecht

Pulse cyclophosphamide to treat idiopathic thrombocytopenic purpura [letter; comment]

DM Reid,NR Shulman

ERRATUM

Erratum for vol. 85, p. 1263

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