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Issue Archive

Volume 84, Issue 12
December 15 1994
Blood Cover Image for Volume 84, Issue 12
In this Issue

Table of Contents

PHOTOGRAPHS

Photograph
A. M. Dvorak
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EDITORIALS

What defines a pluripotent hematopoietic stem cell (PHSC): will the real PHSC please stand up! [editorial]
D Orlic,DM Bodine
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REVIEW

Fanconi anemia and novel strategies for therapy
JM Liu,M Buchwald,CE Walsh,NS Young
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Interleukin-12: a cytokine produced by antigen-presenting cells with immunoregulatory functions in the generation of T-helper cells type 1 and cytotoxic lymphocytes
G Trinchieri
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Marrow transplantation for patients in accelerated phase of chronic myeloid leukemia
RA Clift,CD Buckner,ED Thomas,E Bryant,C Anasetti,WI Bensinger,R Bowden,HJ Deeg,KC Doney,LD Fisher
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ARTICLES

Organization of the gene for human platelet/endothelial cell adhesion molecule-1 shows alternatively spliced isoforms and a functionally complex cytoplasmic domain
NE Kirschbaum,RJ Gumina,PJ Newman
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Candidate tumor-suppressor genes MTS1 (p16INK4A) and MTS2 (p15INK4B) display frequent homozygous deletions in primary cells from T- but not from B-cell lineage acute lymphoblastic leukemias [see comments]
J Hebert,JM Cayuela,J Berkeley,F Sigaux
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In vitro megakaryocytopoietic and thrombopoietic activity of c-mpl ligand (TPO) on purified murine hematopoietic stem cells
FC Zeigler,F de Sauvage,HR Widmer,GA Keller,C Donahue,RD Schreiber,B Malloy,P Hass,D Eaton,W Matthews
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Identification of potential hot spots in the carboxy-terminal part of the Epstein-Barr virus (EBV) BNLF-1 gene in both malignant and benign EBV-associated diseases: high frequency of a 30-bp deletion in Malaysian and Danish peripheral T-cell lymphomas
K Sandvej,SC Peh,BS Andresen,G Pallesen
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Long-term follow-up of patients with hairy cell leukemia after treatment with 2'-deoxycoformycin
EH Kraut,MR Grever,BA Bouroncle
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Randomized comparison of interferon-alpha with busulfan and hydroxyurea in chronic myelogenous leukemia. The German CML Study Group [see comments]
R Hehlmann,H Heimpel,J Hasford,HJ Kolb,H Pralle,DK Hossfeld,W Queisser,H Loffler,A Hochhaus,B Heinze
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Changes in G protein pattern and in G protein-dependent signaling during erythropoietin- and dimethylsulfoxide-induced differentiation of murine erythroleukemia cells
F Kesselring,K Spicher,H Porzig
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Synergistic actions of stem cell factor and other burst-promoting activities on proliferation of CD34+ highly purified blood progenitors expressing HLA-DR or different levels of c-kit protein
Y Sonoda,H Sakabe,Y Ohmisono,S Tanimukai,S Yokota,S Nakagawa,SC Clark,T Abe
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Retinoids (all-trans and 9-cis retinoic acid) stimulate production of macrophage colony-stimulating factor and granulocyte-macrophage colony- stimulating factor by human bone marrow stromal cells
H Nakajima,M Kizaki,A Sonoda,S Mori,K Harigaya,Y Ikeda
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Hydrocortisone differentially affects the ability of murine stromal cells and human marrow-derived adherent cells to promote the differentiation of CD34++/CD38- long-term culture-initiating cells
L Croisille,I Auffray,A Katz,B Izac,W Vainchenker,L Coulombel
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Regulation of interleukin-11 protein and mRNA expression in neonatal and adult fibroblasts and endothelial cells
Y Suen,M Chang,SM Lee,JS Buzby,MS Cairo
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Induction of tyrosine phosphorylation of Vav and expression of Pim-1 correlates with Jak2-mediated growth signaling from the erythropoietin receptor
O Miura,Y Miura,N Nakamura,FW Quelle,BA Witthuhn,JN Ihle,N Aoki
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Regulation of cytokine expression by interferon-alpha in human bone marrow stromal cells: inhibition of hematopoietic growth factors and induction of interleukin-1 receptor antagonist
MJ Aman,U Keller,G Derigs,M Mohamadzadeh,C Huber,C Peschel
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Cytokine production by primary bone marrow megakaryocytes
S Jiang,JD Levine,Y Fu,B Deng,R London,JE Groopman,H Avraham
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Mutual inhibition of murine erythropoiesis and granulopoiesis during combined erythropoietin, granulocyte colony-stimulating factor, and stem cell factor administration: in vivo interactions and dose-response surfaces
G de Haan,C Engel,B Dontje,W Nijhof,M Loeffler
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The STRO-1+ fraction of adult human bone marrow contains the osteogenic precursors
S Gronthos,SE Graves,S Ohta,PJ Simmons
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Expression and function of the human granulocyte-macrophage colony- stimulating factor receptor alpha subunit
PT Jubinsky,AS Laurie,DG Nathan,J Yetz-Aldepe,CA Sieff
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Molecular cloning, characterization, and chromosomal localization of a novel protein-tyrosine phosphatase, HPTP eta
H Honda,J Inazawa,J Nishida,Y Yazaki,H Hirai
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Identification of a novel thrombin receptor sequence required for activation-dependent responses
WF Bahou,JL Kutok,A Wong,CL Potter,BS Coller
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Prevalence and clinical significance of elevated antiphospholipid antibodies in patients with idiopathic thrombocytopenic purpura
R Stasi,E Stipa,M Masi,F Oliva,A Sciarra,A Perrotti,M Olivieri,G Zaccari,GM Gandolfo,M Galli
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Hereditary antithrombin deficiency: heterogeneity of the molecular basis and mortality in Dutch families
HH van Boven,RJ Olds,SL Thein,PH Reitsma,DA Lane,E Briet,JP Vandenbroucke,FR Rosendaal
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Role of the B domain for factor VIII and factor V expression and function
DD Pittman,KA Marquette,RJ Kaufman
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YC-1, a novel activator of platelet guanylate cyclase
FN Ko,CC Wu,SC Kuo,FY Lee,CM Teng
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A defect in the early phase of T-cell receptor-mediated T-cell activation in patients with common variable immunodeficiency
MB Fischer,I Hauber,H Eggenbauer,V Thon,E Vogel,E Schaffer,J Lokaj,J Litzman,HM Wolf,JW Mannhalter
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Interleukin-1 induces interleukin-8 secretion from endothelial cells by a juxtacrine mechanism
G Kaplanski,C Farnarier,S Kaplanski,R Porat,L Shapiro,P Bongrand,CA Dinarello
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Expression and regulation of tumor necrosis factor, interleukin-2, and hematopoietic growth factor receptors in B-cell chronic lymphocytic leukemia
L Trentin,R Zambello,C Agostini,C Enthammer,A Cerutti,F Adami,S Zamboni,G Semenzato
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Identification of a specific HLA class II haplotype strongly associated with susceptibility to cyclosporine-dependent aplastic anemia
S Nakao,H Takamatsu,T Chuhjo,M Ueda,S Shiobara,T Matsuda,T Kaneshige,H Mizoguchi
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Changes in cytokine secretion patterns of CD4+ T-cell clones in human immunodeficiency virus infection
L Meyaard,SA Otto,IP Keet,RA van Lier,F Miedema
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Decreased macrophage colony-stimulating factor mRNA expression from activated cord versus adult mononuclear cells: altered posttranscriptional stability
Y Suen,SM Lee,J Schreurs,E Knoppel,MS Cairo
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Early myeloablative therapy for multiple myeloma
R Alexanian,MA Dimopoulos,J Hester,K Delasalle,R Champlin
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Characterization of a vitamin D3-resistant human chronic myelogenous leukemia cell line
SR Lasky,MR Posner,K Iwata,A Santos-Moore,A Yen,V Samuel,J Clark,AL Maizel
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Abnormal expression of the p53-binding protein MDM2 in Hodgkin's disease
M Chilosi,C Doglioni,F Menestrina,L Montagna,A Rigo,M Lestani,M Barbareschi,A Scarpa,GM Mariuzzi,G Pizzolo
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Nonrandom cytogenetic changes accompany malignant progression in clonal lines abelson virus-infected lymphocytes
SS Clark,Y Liang,CK Reedstrom,SQ Wu
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Immunomorphologic analysis of bone marrow biopsies after treatment with 2-chlorodeoxyadenosine for hairy cell leukemia
DJ Ellison,RW Sharpe,BA Robbins,JC Spinosa,JD Leopard,A Saven,LD Piro
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Synergistic growth inhibitory and differentiating effects of trimidox and tiazofurin in human promyelocytic leukemia HL-60 cells
T Szekeres,M Fritzer,H Strobl,K Gharehbaghi,G Findenig,HL Elford,C Lhotka,HJ Schoen,HN Jayaram
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Kit ligand/mast cell growth factor-independent differentiation of mast cells in myelodysplasia and chronic myeloid leukemic blast crisis
P Valent,E Spanblochl,HC Bankl,WR Sperr,C Marosi,H Pirc-Danoewinata,I Virgolini,HG Eichler,H Agis,C Sillaber
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Studies of human cord blood dendritic cells: evidence for functional immaturity
DW Hunt,HI Huppertz,HJ Jiang,RE Petty
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alpha-Amino butyric acid cannot reactivate the silenced gamma gene of the beta locus YAC transgenic mouse
B Pace,Q Li,K Peterson,G Stamatoyannopoulos
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Molecular analysis of the structure and expression of the RH locus in individuals with D--, Dc-, and DCw- gene complexes
B Cherif-Zahar,V Raynal,AM D'Ambrosio,JP Cartron,Y Colin
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Rapid genotyping of the five major platelet alloantigens by reverse dot- blot hybridization
PF Bray,Y Jin,T Kickler
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Clonal dysregulation of the antibody response to tetanus-toxoid after bone marrow transplantation
EJ Gerritsen,MJ Van Tol,MB Van 't Veer,JM Wels,IM Khouw,CR Touw,CM Jol-Van Der Zijde,J Hermans,HC Rumke,J Radl
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MULTICENTER STUDY

Induction of anti-recombinant human granulocyte-macrophage colony- stimulating factor (Escherichia coli-derived) antibodies and clinical effects in nonimmunocompromised patients
P Ragnhammar,HJ Friesen,JE Frodin,AK Lefvert,M Hassan,A Osterborg,H Mellstedt
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LETTER

Altered retinoid dose-response of retinoic acid-resistant HL-60 cells [letter]
N Sun,XP Li,XP Hu,E Paietta,R Gallagher
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Evidence that a second human tissue factor pathway inhibitor (TFPI-2) and human placental protein 5 are equivalent [letter]
W Kisiel,CA Sprecher,DC Foster
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Mixed chimerism after bone marrow transplantation and the risk of relapse [letter]
E Roux,C Helg,B Chapius,M Jeannet,E Roosnek
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All Issues

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