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Issue Archive

Volume 130, Issue 6
August 10 2017
Issue Cover

Table of Contents

INSIDE BLOOD COMMENTARIES

INSIDE BLOOD COMMENTARY
Hitting the target in IDH2 mutant AML
Clinical Trials & Observations
Bas J. Wouters
View Articletitled, Hitting the target in <em>IDH2</em> mutant AML
INSIDE BLOOD COMMENTARY
Prevalent premalignancy
Adam S. Sperling,Benjamin L. Ebert
View Articletitled, Prevalent premalignancy
INSIDE BLOOD COMMENTARY
Let's give BACH2 a breath of fresh air
Francesco Bertoni
View Articletitled, Let's give BACH2 a breath of fresh air

PERSPECTIVE

Dysfunctional diversity of p53 proteins in adult acute myeloid leukemia: projections on diagnostic workup and therapy
Clinical Trials & Observations
Miron Prokocimer,Alina Molchadsky,Varda Rotter
View Articletitled, Dysfunctional diversity of p53 proteins in adult acute myeloid leukemia: projections on diagnostic workup and therapy
Supplemental data

HOW I TREAT

How I use laboratory monitoring of antiplatelet therapy
Alan D. Michelson,Deepak L. Bhatt
View Articletitled, How I use laboratory monitoring of antiplatelet therapy

CLINICAL TRIALS AND OBSERVATIONS

Enasidenib in mutant IDH2 relapsed or refractory acute myeloid leukemia
Clinical Trials & Observations
Eytan M. Stein,Courtney D. DiNardo,Daniel A. Pollyea,Amir T. Fathi,Gail J. Roboz,Jessica K. Altman,Richard M. Stone,Daniel J. DeAngelo,Ross L. Levine,Ian W. Flinn,Hagop M. Kantarjian,Robert Collins,Manish R. Patel,Arthur E. Frankel,Anthony Stein,Mikkael A. Sekeres,Ronan T. Swords,Bruno C. Medeiros,Christophe Willekens,Paresh Vyas,Alessandra Tosolini,Qiang Xu,Robert D. Knight,Katharine E. Yen,Sam Agresta,Stephane de Botton,Martin S. Tallman
View Articletitled, Enasidenib in mutant <em>IDH2</em> relapsed or refractory acute myeloid leukemia
Supplemental data
Enasidenib induces acute myeloid leukemia cell differentiation to promote clinical response
Clinical Trials & Observations
Michael D. Amatangelo,Lynn Quek,Alan Shih,Eytan M. Stein,Mikhail Roshal,Muriel D. David,Benoit Marteyn,Noushin Rahnamay Farnoud,Stephane de Botton,Olivier A. Bernard,Bin Wu,Katharine E. Yen,Martin S. Tallman,Elli Papaemmanuil,Virginie Penard-Lacronique,Anjan Thakurta,Paresh Vyas,Ross L. Levine
View Articletitled, Enasidenib induces acute myeloid leukemia cell differentiation to promote clinical response
Supplemental data

HEMATOPOIESIS AND STEM CELLS

Clonal hematopoiesis, with and without candidate driver mutations, is common in the elderly
Florian Zink,Simon N. Stacey,Gudmundur L. Norddahl,Michael L. Frigge,Olafur T. Magnusson,Ingileif Jonsdottir,Thorgeir E. Thorgeirsson,Asgeir Sigurdsson,Sigurjon A. Gudjonsson,Julius Gudmundsson,Jon G. Jonasson,Laufey Tryggvadottir,Thorvaldur Jonsson,Agnar Helgason,Arnaldur Gylfason,Patrick Sulem,Thorunn Rafnar,Unnur Thorsteinsdottir,Daniel F. Gudbjartsson,Gisli Masson,Augustine Kong,Kari Stefansson
View Articletitled, Clonal hematopoiesis, with and without candidate driver mutations, is common in the elderly
Supplemental data
DNMT3A and TET2 dominate clonal hematopoiesis and demonstrate benign phenotypes and different genetic predispositions
Manuel Buscarlet,Sylvie Provost,Yassamin Feroz Zada,Amina Barhdadi,Vincent Bourgoin,Guylaine Lépine,Luigina Mollica,Natasha Szuber,Marie-Pierre Dubé,Lambert Busque
View Articletitled, <em>DNMT3A</em> and <em>TET2</em> dominate clonal hematopoiesis and demonstrate benign phenotypes and different genetic predispositions
Supplemental data

LYMPHOID NEOPLASIA

Bifurcated BACH2 control coordinates mantle cell lymphoma survival and dispersal during hypoxia
Han Zhang,Zheng Chen,Roberto N. Miranda,L. Jeffrey Medeiros,Nami McCarty
View Articletitled, Bifurcated BACH2 control coordinates mantle cell lymphoma survival and dispersal during hypoxia
Supplemental data
S100-A9 protein in exosomes from chronic lymphocytic leukemia cells promotes NF-κB activity during disease progression
Daniel Prieto,Natalia Sotelo,Noé Seija,Sandra Sernbo,Cecilia Abreu,Rosario Durán,Magdalena Gil,Estefanía Sicco,Victoria Irigoin,Carolina Oliver,Ana Inés Landoni,Raúl Gabus,Guillermo Dighiero,Pablo Oppezzo
View Articletitled, S100-A9 protein in exosomes from chronic lymphocytic leukemia cells promotes NF-κB activity during disease progression
Supplemental data

MYELOID NEOPLASIA

JAK1/2 and BCL2 inhibitors synergize to counteract bone marrow stromal cell–induced protection of AML
Riikka Karjalainen,Tea Pemovska,Mihaela Popa,Minxia Liu,Komal K. Javarappa,Muntasir M. Majumder,Bhagwan Yadav,David Tamborero,Jing Tang,Dmitrii Bychkov,Mika Kontro,Alun Parsons,Minna Suvela,Mireia Mayoral Safont,Kimmo Porkka,Tero Aittokallio,Olli Kallioniemi,Emmet McCormack,Bjørn T. Gjertsen,Krister Wennerberg,Jonathan Knowles,Caroline A. Heckman
View Articletitled, JAK1/2 and BCL2 inhibitors synergize to counteract bone marrow stromal cell–induced protection of AML
Supplemental data

RED CELLS, IRON, AND ERYTHROPOIESIS

KLF1 drives the expression of fetal hemoglobin in British HPFH
Brief Report
Beeke Wienert,Gabriella E. Martyn,Ryo Kurita,Yukio Nakamura,Kate G. R. Quinlan,Merlin Crossley
View Articletitled, KLF1 drives the expression of fetal hemoglobin in British HPFH
Supplemental data

THROMBOSIS AND HEMOSTASIS

Frequency and epitope specificity of anti–factor VIII C1 domain antibodies in acquired and congenital hemophilia A
Joerg Kahle,Aleksander Orlowski,Diana Stichel,John F. Healey,Ernest T. Parker,Marc Jacquemin,Manuela Krause,Andreas Tiede,Dirk Schwabe,Pete Lollar,Christoph Königs
View Articletitled, Frequency and epitope specificity of anti–factor VIII C1 domain antibodies in acquired and congenital hemophilia A
Supplemental data
The disulfide isomerase ERp72 supports arterial thrombosis in mice
Junsong Zhou,Yi Wu,Fengwu Chen,Lu Wang,Lubica Rauova,Vincent M. Hayes,Mortimer Poncz,Hong Li,Tong Liu,Junling Liu,David W. Essex
View Articletitled, The disulfide isomerase ERp72 supports arterial thrombosis in mice
Supplemental data

LETTERS TO BLOOD

Upregulation of lysyl oxidase and adhesion to collagen of human megakaryocytes and platelets in primary myelofibrosis
Vittorio Abbonante,Vipul Chitalia,Vittorio Rosti,Orly Leiva,Shinobu Matsuura,Alessandra Balduini,Katya Ravid
View Articletitled, Upregulation of lysyl oxidase and adhesion to collagen of human megakaryocytes and platelets in primary myelofibrosis
Supplemental data
Accumulation of classical monocytes defines a subgroup of MDS that frequently evolves into CMML
Dorothée Selimoglu-Buet,Bouchra Badaoui,Emmanuel Benayoun,Andréa Toma,Pierre Fenaux,Bruno Quesnel,Gabriel Etienne,Thorsten Braun,Nassera Abermil,Margot Morabito,Nathalie Droin,Eric Solary,Orianne Wagner-Ballon,on behalf of the Groupe Francophone des Myélodysplasies,on behalf of the Groupe Francophone des Myélodysplasies,on behalf of the Groupe Francophone des Myélodysplasies,on behalf of the Groupe Francophone des Myélodysplasies,on behalf of the Groupe Francophone des Myélodysplasies,on behalf of the Groupe Francophone des Myélodysplasies,on behalf of the Groupe Francophone des Myélodysplasies,on behalf of the Groupe Francophone des Myélodysplasies,on behalf of the Groupe Francophone des Myélodysplasies,on behalf of the Groupe Francophone des Myélodysplasies,on behalf of the Groupe Francophone des Myélodysplasies,on behalf of the Groupe Francophone des Myélodysplasies,on behalf of the Groupe Francophone des Myélodysplasies
View Articletitled, Accumulation of classical monocytes defines a subgroup of MDS that frequently evolves into CMML

BLOOD WORK

An intrasinusoidal extracavitary variant of primary effusion lymphoma
Anna S. Nam,Wayne Tam
View Articletitled, An intrasinusoidal extracavitary variant of primary effusion lymphoma
Intravascular large cell lymphoma of NK/T-cell type, EBV positive
Clinical Trials & Observations
Linda Okonkwo,Elaine S. Jaffe
View Articletitled, Intravascular large cell lymphoma of NK/T-cell type, EBV positive
All Issues

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