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Issue Archive

Volume 130, Issue 4
July 27 2017
Issue Cover

Table of Contents

INSIDE BLOOD COMMENTARIES

INSIDE BLOOD COMMENTARY
CMML/JMML PDXs: as easy as 1, 2, NSG-SGM3
Rachel E. Rau
View Articletitled, CMML/JMML PDXs: as easy as 1, 2, NSG-SGM3
INSIDE BLOOD COMMENTARY
R-CHOP in NLPHL: who should receive it?
Clinical Trials & Observations
Dennis A. Eichenauer,Andreas Engert
View Articletitled, R-CHOP in NLPHL: who should receive it?
INSIDE BLOOD COMMENTARY
A novel role for p53 in self-tolerance
Brian M. Larsen,Avinash Bhandoola
View Articletitled, A novel role for p53 in self-tolerance
INSIDE BLOOD COMMENTARY
SOX11 holds mantle cell lymphoma’s key to home
David Dominguez-Sola
View Articletitled, SOX11 holds mantle cell lymphoma’s key to home
INSIDE BLOOD COMMENTARY
KRASG12D, pulmonary LCH, and atorvastatin
Achille Aouba
View Articletitled, KRAS<sup>G12D</sup>, pulmonary LCH, and atorvastatin
INSIDE BLOOD COMMENTARY
Hot therapy for cold agglutinin disease
Ulrich Jaeger
View Articletitled, Hot therapy for cold agglutinin disease
INSIDE BLOOD COMMENTARY
Microbiome influences von Willebrand factor
Roger J. S. Preston,James S. O’Donnell
View Articletitled, Microbiome influences von Willebrand factor

PLENARY PAPER

MYELOID NEOPLASIA
Robust patient-derived xenografts of MDS/MPN overlap syndromes capture the unique characteristics of CMML and JMML
Akihide Yoshimi,Maria E. Balasis,Alexis Vedder,Kira Feldman,Yan Ma,Hailing Zhang,Stanley Chun-Wei Lee,Christopher Letson,Sandrine Niyongere,Sydney X. Lu,Markus Ball,Justin Taylor,Qing Zhang,Yulong Zhao,Salma Youssef,Young Rock Chung,Xiao Jing Zhang,Benjamin H. Durham,Wendy Yang,Alan F. List,Mignon L. Loh,Virginia Klimek,Michael F. Berger,Elliot Stieglitz,Eric Padron,Omar Abdel-Wahab
View Articletitled, Robust patient-derived xenografts of MDS/MPN overlap syndromes capture the unique characteristics of CMML and JMML
Supplemental data

PERSPECTIVE

Introduction to a review series on precision hematology
Clinical Trials & Observations
Benjamin L. Ebert
View Articletitled, Introduction to a review series on precision hematology

REVIEW SERIES

Diagnosis and classification of hematologic malignancies on the basis of genetics
Clinical Trials & Observations
Justin Taylor,Wenbin Xiao,Omar Abdel-Wahab
View Articletitled, Diagnosis and classification of hematologic malignancies on the basis of genetics
Genetic predisposition to hematologic malignancies: management and surveillance
Clinical Trials & Observations
Lucy A. Godley,Akiko Shimamura
View Articletitled, Genetic predisposition to hematologic malignancies: management and surveillance
The relative utilities of genome-wide, gene panel, and individual gene sequencing in clinical practice
Clinical Trials & Observations
Frank C. Kuo,Brenton G. Mar,R. Coleman Lindsley,Neal I. Lindeman
View Articletitled, The relative utilities of genome-wide, gene panel, and individual gene sequencing in clinical practice
High-throughput sequencing for noninvasive disease detection in hematologic malignancies
Clinical Trials & Observations
Florian Scherer,David M. Kurtz,Maximilian Diehn,Ash A. Alizadeh
View Articletitled, High-throughput sequencing for noninvasive disease detection in hematologic malignancies
The NCI Genomic Data Commons as an engine for precision medicine
Clinical Trials & Observations
Mark A. Jensen,Vincent Ferretti,Robert L. Grossman,Louis M. Staudt
View Articletitled, The NCI Genomic Data Commons as an engine for precision medicine
Ethical considerations in genomic testing for hematologic disorders
Clinical Trials & Observations
Jonathan M. Marron,Steven Joffe
View Articletitled, Ethical considerations in genomic testing for hematologic disorders

CLINICAL TRIALS AND OBSERVATIONS

Presenting ADAMTS13 antibody and antigen levels predict prognosis in immune-mediated thrombotic thrombocytopenic purpura
Clinical Trials & Observations
Ferras Alwan,Chiara Vendramin,Karen Vanhoorelbeke,Katy Langley,Vickie McDonald,Steve Austin,Amanda Clark,William Lester,Richard Gooding,Tina Biss,Tina Dutt,Nichola Cooper,Oliver Chapman,Tanya Cranfield,Kenny Douglas,H. G. Watson,J. J. van Veen,Keith Sibson,William Thomas,Lynn Manson,Quentin A. Hill,Sylvia Benjamin,Debra Ellis,John-Paul Westwood,Mari Thomas,Marie Scully
View Articletitled, Presenting ADAMTS13 antibody and antigen levels predict prognosis in immune-mediated thrombotic thrombocytopenic purpura
Encouraging activity for R-CHOP in advanced stage nodular lymphocyte–predominant Hodgkin lymphoma
Clinical Trials & Observations
Michelle A. Fanale,Chan Yoon Cheah,Amy Rich,L. Jeffrey Medeiros,Chao-Ming Lai,Yasuhiro Oki,Jorge E. Romaguera,Luis E. Fayad,F. B. Hagemeister,Felipe Samaniego,Maria A. Rodriguez,Sattva S. Neelapu,Hun J. Lee,Loretta Nastoupil,Nathan H. Fowler,Francesco Turturro,Jason R. Westin,Michael L. Wang,Peter McLaughlin,Chelsea C. Pinnix,Sarah A. Milgrom,Bouthaina Dabaja,Sandra B. Horowitz,Anas Younes
View Articletitled, Encouraging activity for R-CHOP in advanced stage nodular lymphocyte–predominant Hodgkin lymphoma

IMMUNOBIOLOGY AND IMMUNOTHERAPY

Thymic epithelial cells require p53 to support their long-term function in thymopoiesis in mice
Pedro M. Rodrigues,Ana R. Ribeiro,Chiara Perrod,Jonathan J. M. Landry,Leonor Araújo,Isabel Pereira-Castro,Vladimir Benes,Alexandra Moreira,Helena Xavier-Ferreira,Catarina Meireles,Nuno L. Alves
View Articletitled, Thymic epithelial cells require p53 to support their long-term function in thymopoiesis in mice
Supplemental data

LYMPHOID NEOPLASIA

BCL2 expression in DLBCL: reappraisal of immunohistochemistry with new criteria for therapeutic biomarker evaluation
Naoko Tsuyama,Seiji Sakata,Satoko Baba,Yuko Mishima,Noriko Nishimura,Kyoko Ueda,Masahiro Yokoyama,Yasuhito Terui,Kiyohiko Hatake,Masanobu Kitagawa,Naoki Ishizuka,Naoto Tomita,Kengo Takeuchi
View Articletitled, BCL2 expression in DLBCL: reappraisal of immunohistochemistry with new criteria for therapeutic biomarker evaluation
Supplemental data
SOX11 promotes tumor protective microenvironment interactions through CXCR4 and FAK regulation in mantle cell lymphoma
Patricia Balsas,Jara Palomero,Álvaro Eguileor,Marta Leonor Rodríguez,Maria Carmela Vegliante,Ester Planas-Rigol,Marta Sureda-Gómez,Maria C. Cid,Elias Campo,Virginia Amador
View Articletitled, SOX11 promotes tumor protective microenvironment interactions through CXCR4 and FAK regulation in mantle cell lymphoma
Supplemental data

MYELOID NEOPLASIA

KRASG12D expression in lung-resident myeloid cells promotes pulmonary LCH-like neoplasm sensitive to statin treatment
Tamihiro Kamata,Susan Giblett,Catrin Pritchard
View Articletitled, KRAS<sup>G12D</sup> expression in lung-resident myeloid cells promotes pulmonary LCH-like neoplasm sensitive to statin treatment
Supplemental data

PLATELETS AND THROMBOPOIESIS

Platelet amyloid precursor protein is a modulator of venous thromboembolism in mice
Ilaria Canobbio,Caterina Visconte,Stefania Momi,Gianni Francesco Guidetti,Marta Zarà,Jessica Canino,Emanuela Falcinelli,Paolo Gresele,Mauro Torti
View Articletitled, Platelet amyloid precursor protein is a modulator of venous thromboembolism in mice

RED CELLS, IRON, AND ERYTHROPOIESIS

Bendamustine plus rituximab for chronic cold agglutinin disease: results of a Nordic prospective multicenter trial
Clinical Trials & Observations
Sigbjørn Berentsen,Ulla Randen,Markku Oksman,Henrik Birgens,Tor Henrik Anderson Tvedt,Jakob Dalgaard,Eivind Galteland,Einar Haukås,Robert Brudevold,Jon Hjalmar Sørbø,Inger Anne Næss,Agnieszka Malecka,Geir E. Tjønnfjord
View Articletitled, Bendamustine plus rituximab for chronic cold agglutinin disease: results of a Nordic prospective multicenter trial

THROMBOSIS AND HEMOSTASIS

Gut microbiota regulate hepatic von Willebrand factor synthesis and arterial thrombus formation via Toll-like receptor-2
Sven Jäckel,Klytaimnistra Kiouptsi,Maren Lillich,Tim Hendrikx,Avinash Khandagale,Bettina Kollar,Nives Hörmann,Cora Reiss,Saravanan Subramaniam,Eivor Wilms,Katharina Ebner,Marie-Luise von Brühl,Philipp Rausch,John F. Baines,Sandra Haberichter,Bernhard Lämmle,Christoph J. Binder,Kerstin Jurk,Zaverio M. Ruggeri,Steffen Massberg,Ulrich Walter,Wolfram Ruf,Christoph Reinhardt
View Articletitled, Gut microbiota regulate hepatic von Willebrand factor synthesis and arterial thrombus formation via Toll-like receptor-2
Supplemental data
Exploring the global landscape of genetic variation in coagulation factor XI deficiency
e-blood
Rosanna Asselta,Elvezia Maria Paraboschi,Valeria Rimoldi,Marzia Menegatti,Flora Peyvandi,Ophira Salomon,Stefano Duga
View Articletitled, Exploring the global landscape of genetic variation in coagulation factor XI deficiency

LETTER TO BLOOD

DUSP22 and TP63 rearrangements predict outcome of ALK-negative anaplastic large cell lymphoma: a Danish cohort study
Clinical Trials & Observations
Martin Bjerregård Pedersen,Stephen Jacques Hamilton-Dutoit,Knud Bendix,Rhett P. Ketterling,Patrick P. Bedroske,Ivy M. Luoma,Christopher A. Sattler,Rebecca L. Boddicker,N. Nora Bennani,Peter Nørgaard,Michael Boe Møller,Torben Steiniche,Francesco d’Amore,Andrew L. Feldman
View Articletitled, <em>DUSP22</em> and <em>TP63</em> rearrangements predict outcome of ALK-negative anaplastic large cell lymphoma: a Danish cohort study
Supplemental data

BLOOD WORK

Morphologic features of μ-heavy-chain disease
Lucien Courtois,Pierre Sujobert
View Articletitled, Morphologic features of μ-heavy-chain disease
A rare case of autoimmune hemolytic anemia
Orianne Wagner-Ballon,Marc Michel
View Articletitled, A rare case of autoimmune hemolytic anemia
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