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INSIDE BLOOD COMMENTARIES

INSIDE BLOOD COMMENTARY
INSIDE BLOOD COMMENTARY
INSIDE BLOOD COMMENTARY
INSIDE BLOOD COMMENTARY
INSIDE BLOOD COMMENTARY
INSIDE BLOOD COMMENTARY
INSIDE BLOOD COMMENTARY

PLENARY PAPER

CLINICAL TRIALS AND OBSERVATIONS

BLOOD SPOTLIGHT

HOW I TREAT

CLINICAL TRIALS AND OBSERVATIONS

HEMATOPOIESIS AND STEM CELLS

IMMUNOBIOLOGY

LYMPHOID NEOPLASIA

PLATELETS AND THROMBOPOIESIS

RED CELLS, IRON, AND ERYTHROPOIESIS

THROMBOSIS AND HEMOSTASIS

BLOOD WORK

ERRATA

  • Cover Image

    Cover Image

    issue cover

    Cytoskeleton disorganization caused by the R46W mutation of α-actinin 1. ACTN1 is a gene recently identified as responsible for a new, autosomal-dominant form of inherited thrombocytopenia, ACTN1-related thrombocytopenia. Expression of the mutant R46W form of α-actinin 1 (green) in human fibroblasts causes complete disorganization of the cytoskeleton with actin (red) no longer organized in filaments, which are instead observed in surrounding untransfected cells. See the article by Bottega et al on page 869.

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