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Genotype of proband and thrombophilia screening
Influence of proband’s characteristics on the risk for venous thromboembolism in relatives with factor V Leiden or prothrombin G20210A polymorphisms
Issue Archive
October 10 2013
In this Issue
Table of Contents
INSIDE BLOOD
CLINICAL TRIALS & OBSERVATIONS
Genotype of proband and thrombophilia screening
Clinical Trials & Observations
BLOOD WORK
PLENARY PAPER
Ibrutinib is an irreversible molecular inhibitor of ITK driving a Th1-selective pressure in T lymphocytes
Jason A. Dubovsky,Kyle A. Beckwith,Gayathri Natarajan,Jennifer A. Woyach,Samantha Jaglowski,Yiming Zhong,Joshua D. Hessler,Ta-Ming Liu,Betty Y. Chang,Karilyn M. Larkin,Matthew R. Stefanovski,Danielle L. Chappell,Frank W. Frissora,Lisa L. Smith,Kelly A. Smucker,Joseph M. Flynn,Jeffrey A. Jones,Leslie A. Andritsos,Kami Maddocks,Amy M. Lehman,Richard Furman,Jeff Sharman,Anjali Mishra,Michael A. Caligiuri,Abhay R. Satoskar,Joseph J. Buggy,Natarajan Muthusamy,Amy J. Johnson,John C. Byrd
BLOOD SPOTLIGHT
CLINICAL TRIALS AND OBSERVATIONS
Influence of proband’s characteristics on the risk for venous thromboembolism in relatives with factor V Leiden or prothrombin G20210A polymorphisms
Clinical Trials & Observations
Paolo Bucciarelli,Valerio De Stefano,Serena M. Passamonti,Daniela Tormene,Cristina Legnani,Elena Rossi,Giancarlo Castaman,Paolo Simioni,Michela Cini,Ida Martinelli
HEMATOPOIESIS AND STEM CELLS
A novel role for factor VIII and thrombin/PAR1 in regulating hematopoiesis and its interplay with the bone structure
Anna Aronovich,Yaniv Nur,Elias Shezen,Chava Rosen,Yael Zlotnikov Klionsky,Irit Milman,Liran Yarimi,David Hagin,Gidi Rechavi,Uriel Martinowitz,Takashi Nagasawa,Paul S. Frenette,Dalit Tchorsh-Yutsis,Yair Reisner
IMMUNOBIOLOGY
Virus-associated activation of innate immunity induces rapid disruption of Peyer’s patches in mice
Simon Heidegger,David Anz,Nicolas Stephan,Bernadette Bohn,Tina Herbst,Wolfgang Peter Fendler,Nina Suhartha,Nadja Sandholzer,Sebastian Kobold,Christian Hotz,Katharina Eisenächer,Susanne Radtke-Schuller,Stefan Endres,Carole Bourquin
LYMPHOID NEOPLASIA
Independent prognostic value of BCR-ABL1-like signature and IKZF1 deletion, but not high CRLF2 expression, in children with B-cell precursor ALL
Arian van der Veer,Esmé Waanders,Rob Pieters,Marieke E. Willemse,Simon V. Van Reijmersdal,Lisa J. Russell,Christine J. Harrison,William E. Evans,Vincent H. J. van der Velden,Peter M. Hoogerbrugge,Frank Van Leeuwen,Gabriele Escherich,Martin A. Horstmann,Leila Mohammadi Khankahdani,Dimitris Rizopoulos,Hester A. De Groot-Kruseman,Edwin Sonneveld,Roland P. Kuiper,Monique L. Den Boer
MDM2 phenotypic and genotypic profiling, respective to TP53 genetic status, in diffuse large B-cell lymphoma patients treated with rituximab-CHOP immunochemotherapy: a report from the International DLBCL Rituximab-CHOP Consortium Program
Zijun Y. Xu-Monette,Michael B. Møller,Alexander Tzankov,Santiago Montes-Moreno,Wenwei Hu,Ganiraju C. Manyam,Louise Kristensen,Lei Fan,Carlo Visco,Karen Dybkær,April Chiu,Wayne Tam,Youli Zu,Govind Bhagat,Kristy L. Richards,Eric D. Hsi,William W. L. Choi,J. Han van Krieken,Qin Huang,Jooryung Huh,Weiyun Ai,Maurilio Ponzoni,Andrés J. M. Ferreri,Lin Wu,Xiaoying Zhao,Carlos E. Bueso-Ramos,Sa A. Wang,Ronald S. Go,Yong Li,Jane N. Winter,Miguel A. Piris,L. Jeffrey Medeiros,Ken H. Young
Two main genetic pathways lead to the transformation of chronic lymphocytic leukemia to Richter syndrome
Ekaterina Chigrinova,Andrea Rinaldi,Ivo Kwee,Davide Rossi,Paola M. V. Rancoita,Jonathan C. Strefford,David Oscier,Kostas Stamatopoulos,Theodora Papadaki,Francoise Berger,Ken H. Young,Fiona Murray,Richard Rosenquist,Timothy C. Greiner,Wing C. Chan,Ester M. Orlandi,Marco Lucioni,Roberto Marasca,Giorgio Inghirami,Marco Ladetto,Francesco Forconi,Sergio Cogliatti,Hana Votavova,Steven H. Swerdlow,Stephan Stilgenbauer,Miguel A. Piris,Andras Matolcsy,Dominic Spagnolo,Eugene Nikitin,Alberto Zamò,Valter Gattei,Govind Bhagat,German Ott,Emanuele Zucca,Gianluca Gaidano,Francesco Bertoni
PRDM1/BLIMP1 is commonly inactivated in anaplastic large T-cell lymphoma
Michela Boi,Andrea Rinaldi,Ivo Kwee,Paola Bonetti,Maria Todaro,Fabrizio Tabbò,Roberto Piva,Paola M. V. Rancoita,András Matolcsy,Botond Timar,Thomas Tousseyn,Socorro Maria Rodríguez-Pinilla,Miguel A. Piris,Sílvia Beà,Elias Campo,Govind Bhagat,Steven H. Swerdlow,Andreas Rosenwald,Maurilio Ponzoni,Ken H. Young,Pier Paolo Piccaluga,Reinhard Dummer,Stefano Pileri,Emanuele Zucca,Giorgio Inghirami,Francesco Bertoni
MYELOID NEOPLASIA
Genome-scale expression and transcription factor binding profiles reveal therapeutic targets in transgenic ERG myeloid leukemia
Liat Goldberg,Marloes R. Tijssen,Yehudit Birger,Rebecca L. Hannah,Sarah J. Kinston,Judith Schütte,Dominik Beck,Kathy Knezevic,Ginette Schiby,Jasmine Jacob-Hirsch,Anat Biran,Yoel Kloog,Guido Marcucci,Clara D. Bloomfield,Peter D. Aplan,John E. Pimanda,Berthold Göttgens,Shai Izraeli
Pediatric acute myeloid leukemia with t(8;16)(p11;p13), a distinct clinical and biological entity: a collaborative study by the International-Berlin-Frankfurt-Münster AML-study group
Eva A. Coenen,C. Michel Zwaan,Dirk Reinhardt,Christine J. Harrison,Oskar A. Haas,Valerie de Haas,Vladimir Mihál,Barbara De Moerloose,Marta Jeison,Jeffrey E. Rubnitz,Daisuke Tomizawa,Donna Johnston,Todd A. Alonzo,Henrik Hasle,Anne Auvrignon,Michael Dworzak,Andrea Pession,Vincent H. J. van der Velden,John Swansbury,Kit-fai Wong,Kiminori Terui,Sureyya Savasan,Mark Winstanley,Goda Vaitkeviciene,Martin Zimmermann,Rob Pieters,Marry M. van den Heuvel-Eibrink
PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS
PLATELETS AND THROMBOPOIESIS
THROMBOSIS AND HEMOSTASIS
TRANSPLANTATION
Bone marrow transplantation for thalassemia from alternative related donors: improved outcomes with a new approach
Javid Gaziev,Marco Marziali,Antonella Isgrò,Pietro Sodani,Katia Paciaroni,Cristiano Gallucci,Marco Andreani,Manuela Testi,Gioia De Angelis,Cecilia Alfieri,Luisa Cardarelli,Michela Ribersani,Daniele Armiento,Guido Lucarelli
VASCULAR BIOLOGY
ERRATA
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Cover Image
Cover Image
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Distribution of B220+ B cells (red) in the intestinal lamina propria was analyzed by immunofluorescence in mice treated with poly(I:C), an activator of innate immunity. Immune activation by poly(I:C) did not decrease lymphocyte numbers in the lamina propria. Nuclei are stained with 4,6 diamidino-2-phenylindole (blue). See the article by Heidegger et al on page 2591.
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