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Gene therapy for adenosine deaminase–deficient severe combined immune deficiency: clinical comparison of retroviral vectors and treatment plans
Commonly altered genomic regions in acute myeloid leukemia are enriched for somatic mutations involved in chromatin remodeling and splicing
Rozrolimupab, a mixture of 25 recombinant human monoclonal RhD antibodies, in the treatment of primary immune thrombocytopenia
Issue Archive
November 1 2012
In this Issue
Table of Contents
Inside Blood
Blood Work
Plenary Paper
CLINICAL TRIALS AND OBSERVATIONS
Gene therapy for adenosine deaminase–deficient severe combined immune deficiency: clinical comparison of retroviral vectors and treatment plans
Clinical Trials & Observations
Fabio Candotti,Kit L. Shaw,Linda Muul,Denise Carbonaro,Robert Sokolic,Christopher Choi,Shepherd H. Schurman,Elizabeth Garabedian,Chimene Kesserwan,G. Jayashree Jagadeesh,Pei-Yu Fu,Eric Gschweng,Aaron Cooper,John F. Tisdale,Kenneth I. Weinberg,Gay M. Crooks,Neena Kapoor,Ami Shah,Hisham Abdel-Azim,Xiao-Jin Yu,Monika Smogorzewska,Alan S. Wayne,Howard M. Rosenblatt,Carla M. Davis,Celine Hanson,Radha G. Rishi,Xiaoyan Wang,David Gjertson,Otto O. Yang,Arumugam Balamurugan,Gerhard Bauer,Joanna A. Ireland,Barbara C. Engel,Gregory M. Podsakoff,Michael S. Hershfield,R. Michael Blaese,Robertson Parkman,Donald B. Kohn
Perspectives
How I Treat
Gene Therapy
Hematopoiesis and Stem Cells
Immunobiology
Lymphoid Neoplasia
Inactivation of ribosomal protein L22 promotes transformation by induction of the stemness factor, Lin28B
Shuyun Rao,Sang-Yun Lee,Alejandro Gutierrez,Jacqueline Perrigoue,Roshan J. Thapa,Zhigang Tu,John R. Jeffers,Michele Rhodes,Stephen Anderson,Tamas Oravecz,Stephen P. Hunger,Roman A. Timakhov,Rugang Zhang,Siddharth Balachandran,Gerard P. Zambetti,Joseph R. Testa,A. Thomas Look,David L. Wiest
Myeloid Neoplasia
Commonly altered genomic regions in acute myeloid leukemia are enriched for somatic mutations involved in chromatin remodeling and splicing
e-blood
Anna Dolnik,Julia C. Engelmann,Maren Scharfenberger-Schmeer,Julian Mauch,Sabine Kelkenberg-Schade,Berit Haldemann,Tamara Fries,Jan Krönke,Michael W. M. Kühn,Peter Paschka,Sabine Kayser,Stephan Wolf,Verena I. Gaidzik,Richard F. Schlenk,Frank G. Rücker,Hartmut Döhner,Claudio Lottaz,Konstanze Döhner,Lars Bullinger
Phagocytes, Granulocytes, and Myelopoiesis
Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke
Mathias Gelderblom,Anna Weymar,Christian Bernreuther,Joachim Velden,Priyadharshini Arunachalam,Karin Steinbach,Ellen Orthey,Thiruma V. Arumugam,Frank Leypoldt,Olga Simova,Vivien Thom,Manuel A. Friese,Immo Prinz,Christoph Hölscher,Markus Glatzel,Thomas Korn,Christian Gerloff,Eva Tolosa,Tim Magnus
Platelets and Thrombopoiesis
Rozrolimupab, a mixture of 25 recombinant human monoclonal RhD antibodies, in the treatment of primary immune thrombocytopenia
Clinical Trials & Observations
Tadeusz Robak,Jerzy Windyga,Jacek Trelinski,Mario von Depka Prondzinski,Aristoteles Giagounidis,Chantal Doyen,Ann Janssens,María Teresa Álvarez-Román,Isidro Jarque,Javier Loscertales,Gloria Pérez Rus,Andrzej Hellmann,Wiesław Wiktor Jêdrzejczak,Kazimierz Kuliczkowski,Lana M. Golubovic,Dusica Celeketic,Andrei Cucuianu,Emanuil Gheorghita,Mihaela Lazaroiu,Ofer Shpilberg,Dina Attias,Elena Karyagina,Kalinina Svetlana,Kateryna Vilchevska,Nichola Cooper,Kate Talks,Mukhyaprana Prabhu,Prasad Sripada,T. P. R. Bharadwaj,Henrik Næsted,Niels J. Ø. Skartved,Torben P. Frandsen,Mimi F. Flensburg,Peter S. Andersen,Jørgen Petersen
Red Cells, Iron, and Erythropoiesis
Heme oxygenase-1 gene promoter polymorphism is associated with reduced incidence of acute chest syndrome among children with sickle cell disease
Christopher J. Bean,Sheree L. Boulet,Dorothy Ellingsen,Meredith E. Pyle,Emily A. Barron-Casella,James F. Casella,Amanda B. Payne,Jennifer Driggers,Heidi A. Trau,Genyan Yang,Kimberly Jones,Solomon F. Ofori-Acquah,W. Craig Hooper,Michael R. DeBaun
Thrombosis and Hemostasis
Vascular Biology
Correspondence
Helicobacter pylori eradication as exclusive treatment for limited-stage gastric diffuse large B-cell lymphoma: results of a multicenter phase 2 trial
Andrés J. M. Ferreri,Silvia Govi,Markus Raderer,Antonino Mulè,Alessandro Andriani,Daniele Caracciolo,Liliana Devizzi,Fiorella Ilariucci,Stefano Luminari,Edi Viale,Leonhard Müllauer,Stefania Dell'Oro,Paolo Giorgio Arcidiacono,Maurilio Ponzoni,Caterina Patti
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Cover Image
Cover Image
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A combination of p45NF-E2, Maf G, and Maf K converts adult human dermal fibroblasts into megakaryocytes and functional platelets. The image of the human fibroblast–derived platelet shows typical features for platelets, such as mitochondria, granules, and an open canalicular system. See the article by Ono et al on page 3812.
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