Skip Nav Destination
The principal results of the International Immune Tolerance Study: a randomized dose comparison
Assessment and prognostic value of the European LeukemiaNet criteria for clinicohematologic response, resistance, and intolerance to hydroxyurea in polycythemia vera
A pilot randomized trial of adjuvant rituximab or placebo for nonsplenectomized patients with immune thrombocytopenia
Thigh-length versus below-knee compression elastic stockings for prevention of the postthrombotic syndrome in patients with proximal-venous thrombosis: a randomized trial
Treatment, risk factors, and outcome of adults with relapsed AML after reduced intensity conditioning for allogeneic stem cell transplantation
Issue Archive
February 9 2012
In this Issue
Table of Contents
Inside Blood
Blood Work
Plenary Paper
CLINICAL TRIALS AND OBSERVATIONS
The principal results of the International Immune Tolerance Study: a randomized dose comparison
Clinical Trials & Observations
Review Article
Blood Consult
Hematopoiesis and Stem Cells
The critical role of histone H2A-deubiquitinase Mysm1 in hematopoiesis and lymphocyte differentiation
Anastasia Nijnik,Simon Clare,Christine Hale,Claire Raisen,Rebecca E. McIntyre,Kosuke Yusa,Aaron R. Everitt,Lynda Mottram,Christine Podrini,Mark Lucas,Jeanne Estabel,David Goulding,Sanger Institute Microarray Facility,Sanger Mouse Genetics Project,Niels Adams,Ramiro Ramirez-Solis,Jacqui K. White,David J. Adams,Robert E. W. Hancock,Gordon Dougan
Immunobiology
Alterations in the adenosine metabolism and CD39/CD73 adenosinergic machinery cause loss of Treg cell function and autoimmunity in ADA-deficient SCID
Aisha V. Sauer,Immacolata Brigida,Nicola Carriglio,Raisa Jofra Hernandez,Samantha Scaramuzza,Daniela Clavenna,Francesca Sanvito,Pietro L. Poliani,Nicola Gagliani,Filippo Carlucci,Antonella Tabucchi,Maria Grazia Roncarolo,Elisabetta Traggiai,Anna Villa,Alessandro Aiuti
Lymphoid Neoplasia
KLF9 is a novel transcriptional regulator of bortezomib- and LBH589-induced apoptosis in multiple myeloma cells
Sudha Mannava,DaZhong Zhuang,Jayakumar R. Nair,Rajat Bansal,Joseph A. Wawrzyniak,Shoshanna N. Zucker,Emily E. Fink,Kalyana C. Moparthy,Qiang Hu,Song Liu,Lawrence H. Boise,Kelvin P. Lee,Mikhail A. Nikiforov
Partial plasma cell differentiation as a mechanism of lost major histocompatibility complex class II expression in diffuse large B-cell lymphoma
Sarah T. Wilkinson,Kristie A. Vanpatten,Diane R. Fernandez,Patrick Brunhoeber,Karl E. Garsha,Betty J. Glinsmann-Gibson,Thomas M. Grogan,Julie Teruya-Feldstein,Lisa M. Rimsza
P-selectin glycoprotein ligand regulates the interaction of multiple myeloma cells with the bone marrow microenvironment
Abdel Kareem Azab,Phong Quang,Feda Azab,Costas Pitsillides,Brian Thompson,Triona Chonghaile,John T. Patton,Patricia Maiso,Val Monrose,Antonio Sacco,Hai T. Ngo,Ludmila M. Flores,Charles P. Lin,John L. Magnani,Andrew L. Kung,Anthony Letai,Ruben Carrasco,Aldo M. Roccaro,Irene M. Ghobrial
High ERp5/ADAM10 expression in lymph node microenvironment and impaired NKG2D ligands recognition in Hodgkin lymphomas
Maria Raffaella Zocchi,Silvia Catellani,Paolo Canevali,Sara Tavella,Anna Garuti,Barbara Villaggio,Annalisa Zunino,Marco Gobbi,Giulio Fraternali-Orcioni,Annalisa Kunkl,Jean-Louis Ravetti,Silvia Boero,Alessandra Musso,Alessandro Poggi
Myeloid Neoplasia
Assessment and prognostic value of the European LeukemiaNet criteria for clinicohematologic response, resistance, and intolerance to hydroxyurea in polycythemia vera
Clinical Trials & Observations
Alberto Alvarez-Larrán,Arturo Pereira,Francisco Cervantes,Eduardo Arellano-Rodrigo,Juan-Carlos Hernández-Boluda,Francisca Ferrer-Marín,Anna Angona,Montse Gómez,Begoña Muiña,Helga Guillén,Anabel Teruel,Beatriz Bellosillo,Carmen Burgaleta,Vicente Vicente,Carles Besses
Chronic myeloid leukemia stem cells are not dependent on Bcr-Abl kinase activity for their survival
Ashley Hamilton,G. Vignir Helgason,Mirle Schemionek,Bin Zhang,Svetlana Myssina,Elaine K. Allan,Franck E. Nicolini,Carsten Müller-Tidow,Ravi Bhatia,Valerie G. Brunton,Steffen Koschmieder,Tessa L. Holyoake
Phagocytes, Granulocytes, and Myelopoiesis
Platelets and Thrombopoiesis
A pilot randomized trial of adjuvant rituximab or placebo for nonsplenectomized patients with immune thrombocytopenia
Clinical Trials & Observations
Donald M. Arnold,Nancy M. Heddle,Julie Carruthers,Deborah J. Cook,Mark A. Crowther,Ralph M. Meyer,Yang Liu,Richard J. Cook,Anne McLeod,Janet A. MacEachern,Joy Mangel,David Anderson,Linda Vickars,Alan Tinmouth,Andre C. Schuh,John G. Kelton
Red Cells, Iron, and Erythropoiesis
Defective nuclear localization of Hsp70 is associated with dyserythropoiesis and GATA-1 cleavage in myelodysplastic syndromes
Emilie Frisan,Julie Vandekerckhove,Aurélie de Thonel,Cécile Pierre-Eugène,Alexander Sternberg,Jean-Benoît Arlet,Célia Floquet,Emmanuel Gyan,Olivier Kosmider,François Dreyfus,Anne-Sophie Gabet,Geneviève Courtois,Paresh Vyas,Jean-Antoine Ribeil,Yael Zermati,Catherine Lacombe,Patrick Mayeux,Eric Solary,Carmen Garrido,Olivier Hermine,Michaela Fontenay
Thrombosis and Hemostasis
Thigh-length versus below-knee compression elastic stockings for prevention of the postthrombotic syndrome in patients with proximal-venous thrombosis: a randomized trial
Clinical Trials & Observations
Paolo Prandoni,Franco Noventa,Roberto Quintavalla,Carlo Bova,Benilde Cosmi,Sergio Siragusa,Eugenio Bucherini,Francesco Astorri,Stefano Cuppini,Fabio Dalla Valle,Anthonie W. A. Lensing,Martin H. Prins,Sabina Villalta,on behalf of the Canano Investigators
Transfusion Medicine
Transplantation
Donor B-cell alloantibody deposition and germinal center formation are required for the development of murine chronic GVHD and bronchiolitis obliterans
Mathangi Srinivasan,Ryan Flynn,Andrew Price,Ann Ranger,Jeffrey L. Browning,Patricia A. Taylor,Jerome Ritz,Joseph H. Antin,William J. Murphy,Leo Luznik,Mark J. Shlomchik,Angela Panoskaltsis-Mortari,Bruce R. Blazar
Treatment, risk factors, and outcome of adults with relapsed AML after reduced intensity conditioning for allogeneic stem cell transplantation
Clinical Trials & Observations
Christoph Schmid,Myriam Labopin,Arnon Nagler,Dietger Niederwieser,Luca Castagna,Reza Tabrizi,Michael Stadler,Jürgen Kuball,Jan Cornelissen,Jiri Vorlicek,Gerard Socié,Michele Falda,Lars Vindeløv,Per Ljungman,Graham Jackson,Nicolaus Kröger,Andreas Rank,Emmanuelle Polge,Vanderson Rocha,Mohamad Mohty,on behalf of the Acute Leukaemia Working Party of the European Group for Blood and Marrow Transplantation (EBMT)
Vascular Biology
MicroRNA-27a/b controls endothelial cell repulsion and angiogenesis by targeting semaphorin 6A
Carmen Urbich,David Kaluza,Timo Frömel,Andrea Knau,Katrin Bennewitz,Reinier A. Boon,Angelika Bonauer,Carmen Doebele,Jes-Niels Boeckel,Eduard Hergenreider,Andreas M. Zeiher,Jens Kroll,Ingrid Fleming,Stefanie Dimmeler
-
Cover Image
Cover Image
![issue cover]()
The image shows the increased collagen deposition surrounding the bronchioles of the lungs in mice with chronic GVHD (cGVHD). Mice transplanted with full MHC disparate bone marrow and mature T cells develop extensive fibrosis and inflammation in target organs, such as the lung, compared to mice that receive MHC disparate bone marrow alone. The increase in lung damage, caused by pathogenic antibody deposition, leads to the development of bronchiolitis obliterans, a pathognomonic feature of cGVHD. See the article by Srinivasan et al on page 1570.
- PDF Icon PDF LinkFront Matter
- PDF Icon PDF LinkTable of Contents
- PDF Icon PDF LinkBack Matter
- PDF Icon PDF LinkAdvertising
- PDF Icon PDF LinkEditorial Board
Advertisement
Email alerts
Advertisement
