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Risk stratification–directed donor lymphocyte infusion could reduce relapse of standard-risk acute leukemia patients after allogeneic hematopoietic stem cell transplantation
The role of sex and weight on rituximab clearance and serum elimination half-life in elderly patients with DLBCL
A phase 2 study of the safety, tolerability, and pharmacodynamics of FBS0701, a novel oral iron chelator, in transfusional iron overload
Heparin in pregnant women with previous placenta-mediated pregnancy complications: a prospective, randomized, multicenter, controlled clinical trial
Issue Archive
April 5 2012
In this Issue
Table of Contents
Inside Blood
Blood Work
Plenary Papers
MYELOID NEOPLASIA
Mutations in the spliceosome machinery, a novel and ubiquitous pathway in leukemogenesis
Hideki Makishima,Valeria Visconte,Hirotoshi Sakaguchi,Anna M. Jankowska,Sarah Abu Kar,Andres Jerez,Bartlomiej Przychodzen,Manoj Bupathi,Kathryn Guinta,Manuel G. Afable,Mikkael A. Sekeres,Richard A. Padgett,Ramon V. Tiu,Jaroslaw P. Maciejewski
MYELOID NEOPLASIA
Mutations affecting mRNA splicing define distinct clinical phenotypes and correlate with patient outcome in myelodysplastic syndromes
Frederik Damm,on behalf of the Groupe Francophone des Myélodysplasies,Olivier Kosmider,on behalf of the Groupe Francophone des Myélodysplasies,Véronique Gelsi-Boyer,on behalf of the Groupe Francophone des Myélodysplasies,Aline Renneville,on behalf of the Groupe Francophone des Myélodysplasies,Nadine Carbuccia,on behalf of the Groupe Francophone des Myélodysplasies,Claire Hidalgo-Curtis,on behalf of the Groupe Francophone des Myélodysplasies,Véronique Della Valle,on behalf of the Groupe Francophone des Myélodysplasies,Lucile Couronné,on behalf of the Groupe Francophone des Myélodysplasies,Laurianne Scourzic,on behalf of the Groupe Francophone des Myélodysplasies,Virginie Chesnais,on behalf of the Groupe Francophone des Myélodysplasies,Agnes Guerci-Bresler,on behalf of the Groupe Francophone des Myélodysplasies,Bohrane Slama,on behalf of the Groupe Francophone des Myélodysplasies,Odile Beyne-Rauzy,on behalf of the Groupe Francophone des Myélodysplasies,Aline Schmidt-Tanguy,on behalf of the Groupe Francophone des Myélodysplasies,Aspasia Stamatoullas-Bastard,on behalf of the Groupe Francophone des Myélodysplasies,François Dreyfus,on behalf of the Groupe Francophone des Myélodysplasies,Thomas Prébet,on behalf of the Groupe Francophone des Myélodysplasies,Stéphane de Botton,on behalf of the Groupe Francophone des Myélodysplasies,Norbert Vey,on behalf of the Groupe Francophone des Myélodysplasies,Michael A. Morgan,on behalf of the Groupe Francophone des Myélodysplasies,Nicholas C. P. Cross,on behalf of the Groupe Francophone des Myélodysplasies,Claude Preudhomme,on behalf of the Groupe Francophone des Myélodysplasies,Daniel Birnbaum,on behalf of the Groupe Francophone des Myélodysplasies,Olivier A. Bernard,on behalf of the Groupe Francophone des Myélodysplasies,Michaela Fontenay,on behalf of the Groupe Francophone des Myélodysplasies
Perspectives
Review Articles
How I Treat
Clinical Trials and Observations
Risk stratification–directed donor lymphocyte infusion could reduce relapse of standard-risk acute leukemia patients after allogeneic hematopoietic stem cell transplantation
Clinical Trials & Observations
Chen-Hua Yan,Dai-Hong Liu,Kai-Yan Liu,Lan-Ping Xu,Yan-Rong Liu,Huan Chen,Wei Han,Yu Wang,Ya-Zhen Qin,Xiao-Jun Huang
Hematopoiesis and Stem Cells
Immunobiology
Natural killer cell degranulation capacity predicts early onset of the immune reconstitution inflammatory syndrome (IRIS) in HIV-infected patients with tuberculosis
Polidy Pean,for the Cambodian Early versus Late Introduction of Antiretroviral Drugs (CAMELIA) study team,Eric Nerrienet,for the Cambodian Early versus Late Introduction of Antiretroviral Drugs (CAMELIA) study team,Yoann Madec,for the Cambodian Early versus Late Introduction of Antiretroviral Drugs (CAMELIA) study team,Laurence Borand,for the Cambodian Early versus Late Introduction of Antiretroviral Drugs (CAMELIA) study team,Didier Laureillard,for the Cambodian Early versus Late Introduction of Antiretroviral Drugs (CAMELIA) study team,Marcelo Fernandez,for the Cambodian Early versus Late Introduction of Antiretroviral Drugs (CAMELIA) study team,Olivier Marcy,for the Cambodian Early versus Late Introduction of Antiretroviral Drugs (CAMELIA) study team,Chan Sarin,for the Cambodian Early versus Late Introduction of Antiretroviral Drugs (CAMELIA) study team,Kerya Phon,for the Cambodian Early versus Late Introduction of Antiretroviral Drugs (CAMELIA) study team,Sylvia Taylor,for the Cambodian Early versus Late Introduction of Antiretroviral Drugs (CAMELIA) study team,Gianfranco Pancino,for the Cambodian Early versus Late Introduction of Antiretroviral Drugs (CAMELIA) study team,Françoise Barré-Sinoussi,for the Cambodian Early versus Late Introduction of Antiretroviral Drugs (CAMELIA) study team,Daniel Scott-Algara,for the Cambodian Early versus Late Introduction of Antiretroviral Drugs (CAMELIA) study team
Lymphoid Neoplasia
The role of sex and weight on rituximab clearance and serum elimination half-life in elderly patients with DLBCL
Clinical Trials & Observations
Carsten Müller,Niels Murawski,Martin H. J. Wiesen,Gerhard Held,Viola Poeschel,Samira Zeynalova,Michael Wenger,Christina Nickenig,Norma Peter,Eva Lengfelder,Bernd Metzner,Tanja Rixecker,Carsten Zwick,Michael Pfreundschuh,Marcel Reiser
The mitochondrial ATP-dependent Lon protease: a novel target in lymphoma death mediated by the synthetic triterpenoid CDDO and its derivatives
Steven H. Bernstein,Sundararajan Venkatesh,Min Li,Jae Lee,Bin Lu,Shannon P. Hilchey,Kimberly M. Morse,Hollie M. Metcalfe,Jolanta Skalska,Michael Andreeff,Paul S. Brookes,Carolyn K. Suzuki
Platelets and Thrombopoiesis
Red Cells, Iron, and Erythropoiesis
A phase 2 study of the safety, tolerability, and pharmacodynamics of FBS0701, a novel oral iron chelator, in transfusional iron overload
Clinical Trials & Observations
Ellis J. Neufeld,Renzo Galanello,Vip Viprakasit,Yesim Aydinok,Antonio Piga,Paul Harmatz,Gian Luca Forni,Farrukh T. Shah,Rachael F. Grace,John B. Porter,John C. Wood,Jennifer Peppe,Amber Jones,Hugh Young Rienhoff, Jr
Thrombosis and Hemostasis
Heparin in pregnant women with previous placenta-mediated pregnancy complications: a prospective, randomized, multicenter, controlled clinical trial
Clinical Trials & Observations
Ida Martinelli,for the HAPPY Study Group,Piero Ruggenenti,for the HAPPY Study Group,Irene Cetin,for the HAPPY Study Group,Giorgio Pardi,for the HAPPY Study Group,Annalisa Perna,for the HAPPY Study Group,Patrizia Vergani,for the HAPPY Study Group,Barbara Acaia,for the HAPPY Study Group,Fabio Facchinetti,for the HAPPY Study Group,Giovanni Battista La Sala,for the HAPPY Study Group,Maddalena Bozzo,for the HAPPY Study Group,Stefania Rampello,for the HAPPY Study Group,Luca Marozio,for the HAPPY Study Group,Olimpia Diadei,for the HAPPY Study Group,Giulia Gherardi,for the HAPPY Study Group,Sergio Carminati,for the HAPPY Study Group,Giuseppe Remuzzi,for the HAPPY Study Group,Pier Mannuccio Mannucci,for the HAPPY Study Group
Transplantation
Azacitidine augments expansion of regulatory T cells after allogeneic stem cell transplantation in patients with acute myeloid leukemia (AML)
Oliver C. Goodyear,Mike Dennis,Nadira Y. Jilani,Justin Loke,Shamyla Siddique,Gordon Ryan,Jane Nunnick,Rahela Khanum,Manoj Raghavan,Mark Cook,John A. Snowden,Mike Griffiths,Nigel Russell,John Yin,Charles Crawley,Gordon Cook,Paresh Vyas,Paul Moss,Ram Malladi,Charles F. Craddock
Vascular Biology
Retraction
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Cover Image
Cover Image
The image is a histological micrograph (magnification ×200) of a lung section of a Jam-A knockout (Jam-Agt/gt) mouse showing both macro- and micro-thromboemboli. Pulmonary thromboembolism was induced by injecting a mixture of collagen and epinephrine through the tail vein. See the article by Naik et al on page 3352, which describes a protective role for Jam-A in thrombosis.
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