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B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor–transduced T cells
Retrospective analysis of prognostic factors for angioimmunoblastic T-cell lymphoma: a multicenter cooperative study in Japan
A prospective evaluation of degranulation assays in the rapid diagnosis of familial hemophagocytic syndromes
Chelation use and iron burden in North American and British thalassemia patients: a report from the Thalassemia Longitudinal Cohort
The characteristics and outcomes of parainfluenza virus infections in 200 patients with leukemia or recipients of hematopoietic stem cell transplantation
Risk of complications during hematopoietic stem cell collection in pediatric sibling donors: a prospective European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party study
Early matched sibling hematopoietic cell transplantation for adult AML in first remission using an age-adapted strategy: long-term results of a prospective GOELAMS study
Transplantation in patients with SCID: mismatched related stem cells or unrelated cord blood?
Costimulated tumor-infiltrating lymphocytes are a feasible and safe alternative donor cell therapy for relapse after allogeneic stem cell transplantation
Issue Archive
March 22 2012
In this Issue
Table of Contents
Inside Blood
Blood Work
Plenary Paper
PLENARY PAPER
B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor–transduced T cells
Clinical Trials & Observations
James N. Kochenderfer,Mark E. Dudley,Steven A. Feldman,Wyndham H. Wilson,David E. Spaner,Irina Maric,Maryalice Stetler-Stevenson,Giao Q. Phan,Marybeth S. Hughes,Richard M. Sherry,James C. Yang,Udai S. Kammula,Laura Devillier,Robert Carpenter,Debbie-Ann N. Nathan,Richard A. Morgan,Carolyn Laurencot,Steven A. Rosenberg
Perspectives
Review Article
Hematopoiesis and Stem Cells
Membrane-bound human SCF/KL promotes in vivo human hematopoietic engraftment and myeloid differentiation
Shinsuke Takagi,Yoriko Saito,Atsushi Hijikata,Satoshi Tanaka,Takashi Watanabe,Takanori Hasegawa,Shinobu Mochizuki,Jun Kunisawa,Hiroshi Kiyono,Haruhiko Koseki,Osamu Ohara,Takashi Saito,Shuichi Taniguchi,Leonard D. Shultz,Fumihiko Ishikawa
Engraftment of human HSCs in nonirradiated newborn NOD-scid IL2rγnull mice is enhanced by transgenic expression of membrane-bound human SCF
Michael A. Brehm,Waldemar J. Racki,Jean Leif,Lisa Burzenski,Vishnu Hosur,Amber Wetmore,Bruce Gott,Mary Herlihy,Ronald Ignotz,Raymond Dunn,Leonard D. Shultz,Dale L. Greiner
Immunobiology
B cell–intrinsic deficiency of the Wiskott-Aldrich syndrome protein (WASp) causes severe abnormalities of the peripheral B-cell compartment in mice
Mike Recher,Siobhan O. Burns,Miguel A. de la Fuente,Stefano Volpi,Carin Dahlberg,Jolan E. Walter,Kristin Moffitt,Divij Mathew,Nadine Honke,Philipp A. Lang,Laura Patrizi,Hervé Falet,Marton Keszei,Masayuki Mizui,Eva Csizmadia,Fabio Candotti,Kari Nadeau,Gerben Bouma,Ottavia M. Delmonte,Francesco Frugoni,Angela B. Ferraz Fomin,David Buchbinder,Emma Maria Lundequist,Michel J. Massaad,George C. Tsokos,John Hartwig,John Manis,Cox Terhorst,Raif S. Geha,Scott Snapper,Karl S. Lang,Richard Malley,Lisa Westerberg,Adrian J. Thrasher,Luigi D. Notarangelo
Lymphoid Neoplasia
Retrospective analysis of prognostic factors for angioimmunoblastic T-cell lymphoma: a multicenter cooperative study in Japan
Clinical Trials & Observations
Takashi Tokunaga,Kazuyuki Shimada,Kazuhito Yamamoto,Dai Chihara,Takuji Ichihashi,Rika Oshima,Mitsune Tanimoto,Toshihiro Iwasaki,Atsushi Isoda,Akira Sakai,Hikaru Kobayashi,Kunio Kitamura,Kosei Matsue,Masafumi Taniwaki,Sadahiro Tamashima,Yoshio Saburi,Taro Masunari,Tomoki Naoe,Shigeo Nakamura,Tomohiro Kinoshita
Disruption of BIRC3 associates with fludarabine chemorefractoriness in TP53 wild-type chronic lymphocytic leukemia
Davide Rossi,Marco Fangazio,Silvia Rasi,Tiziana Vaisitti,Sara Monti,Stefania Cresta,Sabina Chiaretti,Ilaria Del Giudice,Giulia Fabbri,Alessio Bruscaggin,Valeria Spina,Clara Deambrogi,Marilisa Marinelli,Rosella Famà,Mariangela Greco,Giulia Daniele,Francesco Forconi,Valter Gattei,Francesco Bertoni,Silvia Deaglio,Laura Pasqualucci,Anna Guarini,Riccardo Dalla-Favera,Robin Foà,Gianluca Gaidano
Myeloid Neoplasia
Phagocytes, Granulocytes, and Myelopoiesis
A prospective evaluation of degranulation assays in the rapid diagnosis of familial hemophagocytic syndromes
Clinical Trials & Observations
Yenan T. Bryceson,Daniela Pende,Andrea Maul-Pavicic,Kimberly C. Gilmour,Heike Ufheil,Thomas Vraetz,Samuel C. Chiang,Stefania Marcenaro,Raffaella Meazza,Ilka Bondzio,Denise Walshe,Gritta Janka,Kai Lehmberg,Karin Beutel,Udo zur Stadt,Nadine Binder,Maurizio Arico,Lorenzo Moretta,Jan-Inge Henter,Stephan Ehl
Platelets and Thrombopoiesis
Red Cells, Iron, and Erythropoiesis
Chelation use and iron burden in North American and British thalassemia patients: a report from the Thalassemia Longitudinal Cohort
Clinical Trials & Observations
Janet L. Kwiatkowski,Hae-Young Kim,Alexis A. Thompson,Charles T. Quinn,Brigitta U. Mueller,Isaac Odame,Patricia J. Giardina,Elliott P. Vichinsky,Jeanne M. Boudreaux,Alan R. Cohen,John B. Porter,Thomas Coates,Nancy F. Olivieri,Ellis J. Neufeld,for the Thalassemia Clinical Research Network
Thrombosis and Hemostasis
F8 gene mutation type and inhibitor development in patients with severe hemophilia A: systematic review and meta-analysis
Samantha C. Gouw,H. Marijke van den Berg,Johannes Oldenburg,Jan Astermark,Philip G. de Groot,Maurizio Margaglione,Arthur R. Thompson,Waander van Heerde,Jorien Boekhorst,Connie H. Miller,Saskia le Cessie,Johanna G. van der Bom
Transplantation
The characteristics and outcomes of parainfluenza virus infections in 200 patients with leukemia or recipients of hematopoietic stem cell transplantation
CME
Roy F. Chemaly,Santosh S. Hanmod,Dhanesh B. Rathod,Shashank S. Ghantoji,Ying Jiang,Arpan Doshi,Karen Vigil,Javier A. Adachi,Andrew M. Khoury,Jeffery Tarrand,Chitra Hosing,Richard Champlin
Risk of complications during hematopoietic stem cell collection in pediatric sibling donors: a prospective European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party study
Clinical Trials & Observations
Jan Styczynski,Adriana Balduzzi,Lidia Gil,Myriam Labopin,Rose-Marie Hamladji,Sarah Marktel,M. Akif Yesilipek,Franca Fagioli,Karoline Ehlert,Martina Matulova,Jean-Hugues Dalle,Jacek Wachowiak,Maurizio Miano,Chiara Messina,Miguel Angel Diaz,Christiane Vermylen,Matthias Eyrich,Isabel Badell,Peter Dreger,Jolanta Gozdzik,Daphna Hutt,Jelena Rascon,Giorgio Dini,Christina Peters,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party,on behalf of the European Group for Blood and Marrow Transplantation Pediatric Diseases Working Party
Early matched sibling hematopoietic cell transplantation for adult AML in first remission using an age-adapted strategy: long-term results of a prospective GOELAMS study
Clinical Trials & Observations
Bruno Lioure,Marie C. Béné,Arnaud Pigneux,Anne Huynh,Patrice Chevallier,Nathalie Fegueux,Didier Blaise,Brigitte Witz,Martine Delain,Jérôme Cornillon,Isabelle Luquet,Odile Blanchet,Pascale Cornillet-Lefebvre,Martin Carré,Mathilde Hunault,Fabrice Larosa,Thierry Lamy,Edouard Randriamalala,Mario Ojeda-Uribe,Christian Berthou,Luc Fornecker,Jean-Luc Harousseau,Didier Bouscary,Norbert Ifrah,Jean-Yves Cahn,on behalf of the GOELAMS,on behalf of the GOELAMS,on behalf of the GOELAMS,on behalf of the GOELAMS,on behalf of the GOELAMS,on behalf of the GOELAMS,on behalf of the GOELAMS,on behalf of the GOELAMS,on behalf of the GOELAMS,on behalf of the GOELAMS,on behalf of the GOELAMS,on behalf of the GOELAMS,on behalf of the GOELAMS,on behalf of the GOELAMS,on behalf of the GOELAMS,on behalf of the GOELAMS,on behalf of the GOELAMS,on behalf of the GOELAMS,on behalf of the GOELAMS,on behalf of the GOELAMS,on behalf of the GOELAMS,on behalf of the GOELAMS,on behalf of the GOELAMS,on behalf of the GOELAMS,on behalf of the GOELAMS
Transplantation in patients with SCID: mismatched related stem cells or unrelated cord blood?
Clinical Trials & Observations
Juliana F. Fernandes,Vanderson Rocha,Myriam Labopin,Benedicte Neven,Despina Moshous,Andrew R. Gennery,Wilhelm Friedrich,Fulvio Porta,Cristina Diaz de Heredia,Donna Wall,Yves Bertrand,Paul Veys,Mary Slatter,Ansgar Schulz,Ka Wah Chan,Michael Grimley,Mouhab Ayas,Tayfun Gungor,Wolfram Ebell,Carmem Bonfim,Krzysztof Kalwak,Pierre Taupin,Stéphane Blanche,H. Bobby Gaspar,Paul Landais,Alain Fischer,Eliane Gluckman,Marina Cavazzana-Calvo,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation,on behalf of Eurocord and the Inborn Errors Working Party of the European Group for Blood and Marrow Transplantation
Costimulated tumor-infiltrating lymphocytes are a feasible and safe alternative donor cell therapy for relapse after allogeneic stem cell transplantation
Brief Report
Nancy M. Hardy,Vicki Fellowes,Jeremy J. Rose,Jeanne Odom,Stefania Pittaluga,Seth M. Steinberg,Bazetta Blacklock-Schuver,Daniele N. Avila,Sarfraz Memon,Roger J. Kurlander,Hahn M. Khuu,Maryalice Stetler-Stevenson,Esther Mena,Andrew J. Dwyer,Bruce L. Levine,Carl H. June,Ran Reshef,Robert H. Vonderheide,Ronald E. Gress,Daniel H. Fowler,Frances T. Hakim,Michael R. Bishop
Correspondence
Other Departments
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Cover Image
Cover Image
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Knocking down filamins A and B resulted in the production of embryonic stem cell–derived proplatelets with abnormally large swellings and proplatelet shafts that generated giant platelets in culture. See the article by Kanaji et al on page 2906.
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