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Hospitalization for pain in patients with sickle cell disease treated with sildenafil for elevated TRV and low exercise capacity
Circulating human CD4 and CD8 T cells do not have large intracellular pools of CCR5
Efficacy and safety of once-weekly and twice-weekly bortezomib in patients with relapsed systemic AL amyloidosis: results of a phase 1/2 study
Effectiveness of high-dose methotrexate in T-cell lymphoblastic leukemia and advanced-stage lymphoblastic lymphoma: a randomized study by the Children's Oncology Group (POG 9404)
Risk stratification of intermediate-risk acute myeloid leukemia: integrative analysis of a multitude of gene mutation and gene expression markers
Iron chelation with deferasirox in adult and pediatric patients with thalassemia major: efficacy and safety during 5 years' follow-up
Pomalidomide augments fetal hemoglobin production without the myelosuppressive effects of hydroxyurea in transgenic sickle cell mice
90Y-Ibritumomab tiuxetan, fludarabine, and TBI-based nonmyeloablative allogeneic transplantation conditioning for patients with persistent high-risk B-cell lymphoma
Genetic variation in recipient B-cell activating factor modulates phenotype of GVHD
Issue Archive
July 28 2011
In this Issue
Table of Contents
Inside Blood
Review Articles
Clinical Trials and Observations
Hospitalization for pain in patients with sickle cell disease treated with sildenafil for elevated TRV and low exercise capacity
CME
Roberto F. Machado,Robyn J. Barst,Nancy A. Yovetich,Kathryn L. Hassell,Gregory J. Kato,Victor R. Gordeuk,J. Simon R. Gibbs,Jane A. Little,Dean E. Schraufnagel,Lakshmanan Krishnamurti,Reda E. Girgis,Claudia R. Morris,Erika B. Rosenzweig,David B. Badesch,Sophie Lanzkron,Onyinye Onyekwere,Oswaldo L. Castro,Vandana Sachdev,Myron A. Waclawiw,Rob Woolson,Jonathan C. Goldsmith,Mark T. Gladwin,on behalf of the walk-PHaSST Investigators and Patients
Gene Therapy
Hematopoiesis and Stem Cells
Ddx18 is essential for cell-cycle progression in zebrafish hematopoietic cells and is mutated in human AML
Elspeth M. Payne,Niccolò Bolli,Jennifer Rhodes,Omar I. Abdel-Wahab,Ross Levine,Cyrus V. Hedvat,Richard Stone,Arati Khanna-Gupta,Hong Sun,John P. Kanki,Hanna T. Gazda,Alan H. Beggs,Finbarr E. Cotter,A. Thomas Look
MiR-17/20/93/106 promote hematopoietic cell expansion by targeting sequestosome 1–regulated pathways in mice
Annemarie Meenhuis,Peter A. van Veelen,Hans de Looper,Nicole van Boxtel,Iris J. van den Berge,Su M. Sun,Erdogan Taskesen,Patrick Stern,Arnoud H. de Ru,Arjan J. van Adrichem,Jeroen Demmers,Mojca Jongen-Lavrencic,Bob Löwenberg,Ivo P. Touw,Phillip A. Sharp,Stefan J. Erkeland
Immunobiology
New mechanism of X-linked anhidrotic ectodermal dysplasia with immunodeficiency: impairment of ubiquitin binding despite normal folding of NEMO protein
Marjorie Hubeau,Flora Ngadjeua,Anne Puel,Laura Israel,Jacqueline Feinberg,Maya Chrabieh,Kiran Belani,Christine Bodemer,Isabelle Fabre,Alessandro Plebani,Stéphanie Boisson-Dupuis,Capucine Picard,Alain Fischer,Alain Israel,Laurent Abel,Michel Veron,Jean-Laurent Casanova,Fabrice Agou,Jacinta Bustamante
Restriction of HIV-1 replication in macrophages and CD4+ T cells from HIV controllers
Asier Sáez-Cirión,Chiraz Hamimi,Anna Bergamaschi,Annie David,Pierre Versmisse,Adeline Mélard,Faroudy Boufassa,Françoise Barré-Sinoussi,Olivier Lambotte,Christine Rouzioux,Gianfranco Pancino,for the ANRS CO18 Cohort
Circulating human CD4 and CD8 T cells do not have large intracellular pools of CCR5
Brief Report
Heather A. Pilch-Cooper,Scott F. Sieg,Thomas J. Hope,Ann Koons,Jean-Michel Escola,Robin Offord,Ronald S. Veazey,Donald E. Mosier,Brian Clagett,Kathy Medvik,Julie K. Jadlowsky,Mark R. Chance,Janna G. Kiselar,James A. Hoxie,Ronald G. Collman,Nadeene E. Riddick,Valentina Mercanti,Oliver Hartley,Michael M. Lederman
Lymphoid Neoplasia
Efficacy and safety of once-weekly and twice-weekly bortezomib in patients with relapsed systemic AL amyloidosis: results of a phase 1/2 study
Clinical Trials & Observations
Donna E. Reece,Ute Hegenbart,Vaishali Sanchorawala,Giampaolo Merlini,Giovanni Palladini,Joan Bladé,Jean-Paul Fermand,Hani Hassoun,Leonard Heffner,Robert A. Vescio,Kevin Liu,Christopher Enny,Dixie-Lee Esseltine,Helgi van de Velde,Andrew Cakana,Raymond L. Comenzo
Effectiveness of high-dose methotrexate in T-cell lymphoblastic leukemia and advanced-stage lymphoblastic lymphoma: a randomized study by the Children's Oncology Group (POG 9404)
Clinical Trials & Observations
Barbara L. Asselin,Meenakshi Devidas,Chenguang Wang,Jeanette Pullen,Michael J. Borowitz,Robert Hutchison,Steven E. Lipshultz,Bruce M. Camitta
miRNA expression in diffuse large B-cell lymphoma treated with chemoimmunotherapy
Santiago Montes-Moreno,Nerea Martinez,Beatriz Sanchez-Espiridión,Ramon Díaz Uriarte,Maria Elena Rodriguez,Anabel Saez,Carlos Montalbán,Gonzalo Gomez,David G. Pisano,Juan Fernando García,Eulogio Conde,Eva Gonzalez-Barca,Andres Lopez,Manuela Mollejo,Carlos Grande,Miguel Angel Martinez,Cherie Dunphy,Eric D. Hsi,Gabrielle B. Rocque,Julie Chang,Ronald S. Go,Carlo Visco,Zijun Xu-Monette,Ken H. Young,Miguel A. Piris
Myeloid Neoplasia
Risk stratification of intermediate-risk acute myeloid leukemia: integrative analysis of a multitude of gene mutation and gene expression markers
Clinical Trials & Observations
Veronika Rockova,Saman Abbas,Bas J. Wouters,Claudia A. J. Erpelinck,H. Berna Beverloo,Ruud Delwel,Wim L. J. van Putten,Bob Löwenberg,Peter J. M. Valk
Phagocytes, Granulocytes, and Myelopoiesis
Red Cells, Iron, and Erythropoiesis
Iron chelation with deferasirox in adult and pediatric patients with thalassemia major: efficacy and safety during 5 years' follow-up
Clinical Trials & Observations
M. Domenica Cappellini,Mohamed Bejaoui,Leyla Agaoglu,Duran Canatan,Marcello Capra,Alan Cohen,Guillermo Drelichman,Marina Economou,Slaheddine Fattoum,Antonis Kattamis,Yurdanur Kilinc,Silverio Perrotta,Antonio Piga,John B. Porter,Louis Griffel,Victor Dong,Joan Clark,Yesim Aydinok
Pomalidomide augments fetal hemoglobin production without the myelosuppressive effects of hydroxyurea in transgenic sickle cell mice
Brief Report
Steffen E. Meiler,Marlene Wade,Ferdane Kutlar,Shobha D. Yerigenahally,Yongjun Xue,Laure A. Moutouh-de Parseval,Laura G. Corral,Paul S. Swerdlow,Abdullah Kutlar
Thrombosis and Hemostasis
Transplantation
90Y-Ibritumomab tiuxetan, fludarabine, and TBI-based nonmyeloablative allogeneic transplantation conditioning for patients with persistent high-risk B-cell lymphoma
Clinical Trials & Observations
Ajay K. Gopal,Katherine A. Guthrie,Joseph Rajendran,John M. Pagel,George Oliveira,David G. Maloney,Manuela C. Matesan,Rainer F. Storb,Oliver W. Press
Genetic variation in recipient B-cell activating factor modulates phenotype of GVHD
Brief Report
William B. Clark,Kristin D. Brown-Gentry,Dana C. Crawford,Kang-Hsien Fan,Jennifer Snavely,Heidi Chen,Bipin N. Savani,Adetola Kassim,John P. Greer,Friedrich G. Schuening,Brian G. Engelhardt,Madan H. Jagasia
Vascular Biology
RhoJ is an endothelial cell-restricted Rho GTPase that mediates vascular morphogenesis and is regulated by the transcription factor ERG
Lei Yuan,Anastasia Sacharidou,Amber N. Stratman,Alexandra Le Bras,Peter J. Zwiers,Katherine Spokes,Manoj Bhasin,Shou-ching Shih,Janice A. Nagy,Grietje Molema,William C. Aird,George E. Davis,Peter Oettgen
Correspondence
Response: absence of CCR5 intracellular pools in most CD4 and CD8 T cells
Heather A. Pilch-Cooper,Scott F. Sieg,Thomas J. Hope,Valentina Mercanti,Robin Offord,Ronald S. Veazey,Donald E. Mosier,Brian Clagett,Julie K. Jadlowsky,Mark R. Chance,Ronald G. Collman,Nadeene E. Riddick,Oliver Hartley,Michael M. Lederman
NOD2/CARD15 gene polymorphisms affect outcome in pediatric allogeneic stem cell transplantation
Hermann Kreyenberg,Andrea Jarisch,Christina Bayer,Blanca Schuster,Andre Willasch,Brigitte Strahm,Bernhard Kremens,Bernd Gruhn,Andre Schrauder,Stefan Burdach,Monika Führer,Claudia Rossig,Hartmut Kabisch,Paul-Gerhard Schlegel,Daniel Stachel,James F. Beck,Christine Mauz-Koerholz,Tje Lin Chung,Ernst Holler,Thomas Klingebiel,Peter Bader
Other Departments
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Cover Image
Cover Image
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Whole body gamma camera images 48 hours after 111In-ibritumomab tiuxetan infusion in a patient with diffuse large B-cell lymphoma: localization to known sites of disease in right skull and pelvis is demonstrated along with normal blood pool activity and expected uptake in liver, spleen, and kidneys. See the article by Gopal et al on page 1132.
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