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Changes in the dynamics of the excess mortality rate in chronic phase-chronic myeloid leukemia over 1990-2007: a population study
Impact of gene expression profiling-based risk stratification in patients with myeloma receiving initial therapy with lenalidomide and dexamethasone
Phase 2 study of rituximab in newly diagnosed stage IA nodular lymphocyte-predominant Hodgkin lymphoma: a report from the German Hodgkin Study Group
Malignancies occurring during therapy with tyrosine kinase inhibitors (TKIs) for chronic myeloid leukemia (CML) and other hematologic malignancies
Elevated plasma glucosylsphingosine in Gaucher disease: relation to phenotype, storage cell markers, and therapeutic response
Romiplostim safety and efficacy for immune thrombocytopenia in clinical practice: 2-year results of 72 adults in a romiplostim compassionate-use program
Outcome of AL amyloidosis after high-dose melphalan and autologous stem cell transplantation: long-term results in a series of 421 patients
Risk factors associated with increased nonrelapse mortality and with poor overall survival in children with chronic graft-versus-host disease
Issue Archive
October 20 2011
In this Issue
Table of Contents
Inside Blood
Blood Work
Plenary Paper
Perspectives
Review Article
Clinical Trials and Observations
Changes in the dynamics of the excess mortality rate in chronic phase-chronic myeloid leukemia over 1990-2007: a population study
Clinical Trials & Observations
Selim Corm,Laurent Roche,Jean-Baptiste Micol,Valérie Coiteux,Nadine Bossard,Franck-Emmanuel Nicolini,Jean Iwaz,Claude Preudhomme,Catherine Roche-Lestienne,Thierry Facon,Laurent Remontet
Hematopoiesis and Stem Cells
Ontogeny stage-independent and high-level clonal expansion in vitro of mouse hematopoietic stem cells stimulated by an engineered NUP98-HOX fusion transcription factor
Sanja Sekulovic,Maura Gasparetto,Véronique Lecault,Corinne A. Hoesli,David G. Kent,Patty Rosten,Adrian Wan,Christy Brookes,Carl L. Hansen,James M. Piret,Clayton Smith,Connie J. Eaves,R. Keith Humphries
Immunobiology
Clonal drift demonstrates unexpected dynamics of the T-cell repertoire in T-large granular lymphocyte leukemia
Michael J. Clemente,Marcin W. Wlodarski,Hideki Makishima,Aaron D. Viny,Isabell Bretschneider,Mohammad Shaik,Nelli Bejanyan,Alan E. Lichtin,Eric D. Hsi,Ronald L. Paquette,Thomas P. Loughran, Jr,Jaroslaw P. Maciejewski
Serological identification of HSP105 as a novel non-Hodgkin lymphoma therapeutic target
Roberta Zappasodi,Italia Bongarzone,Gaia C. Ghedini,Lorenzo Castagnoli,Antonello D. Cabras,Antonella Messina,Monica Tortoreto,Claudio Tripodo,Michele Magni,Carmelo Carlo-Stella,Alessandro M. Gianni,Serenella M. Pupa,Massimo Di Nicola
Lymphoid Neoplasia
Impact of gene expression profiling-based risk stratification in patients with myeloma receiving initial therapy with lenalidomide and dexamethasone
Brief Report
Shaji K. Kumar,Hajime Uno,Susanna J. Jacobus,Scott A. Van Wier,Greg J. Ahmann,Kimberly J. Henderson,Natalie S. Callander,Jessica L. Haug,David S. Siegel,Philip R. Greipp,Rafael Fonseca,S. Vincent Rajkumar
Phase 2 study of rituximab in newly diagnosed stage IA nodular lymphocyte-predominant Hodgkin lymphoma: a report from the German Hodgkin Study Group
Brief Report
Dennis A. Eichenauer,Michael Fuchs,Annette Pluetschow,Beate Klimm,Teresa Halbsguth,Boris Böll,Bastian von Tresckow,Lucia Nogová,Peter Borchmann,Andreas Engert
Myeloid Neoplasia
Malignancies occurring during therapy with tyrosine kinase inhibitors (TKIs) for chronic myeloid leukemia (CML) and other hematologic malignancies
Clinical Trials & Observations
Dushyant Verma,Hagop Kantarjian,Sara S. Strom,Mary Beth Rios,Elias Jabbour,Alfonso Quintas-Cardama,Srdan Verstovsek,Farhad Ravandi,Susan O'Brien,Jorge Cortes
p53 activation of mesenchymal stromal cells partially abrogates microenvironment-mediated resistance to FLT3 inhibition in AML through HIF-1α–mediated down-regulation of CXCL12
Kensuke Kojima,Teresa McQueen,Ye Chen,Rodrigo Jacamo,Marina Konopleva,Naoki Shinojima,Elizabeth Shpall,Xuelin Huang,Michael Andreeff
Phagocytes, Granulocytes, and Myelopoiesis
Elevated plasma glucosylsphingosine in Gaucher disease: relation to phenotype, storage cell markers, and therapeutic response
e-blood
Nick Dekker,Laura van Dussen,Carla E. M. Hollak,Herman Overkleeft,Saskia Scheij,Karen Ghauharali,Mariëlle J. van Breemen,Maria J. Ferraz,Johanna E. M. Groener,Mario Maas,Frits A. Wijburg,Dave Speijer,Anna Tylki-Szymanska,Pramod K. Mistry,Rolf G. Boot,Johannes M. Aerts
Platelets and Thrombopoiesis
Romiplostim safety and efficacy for immune thrombocytopenia in clinical practice: 2-year results of 72 adults in a romiplostim compassionate-use program
Clinical Trials & Observations
Mehdi Khellaf,Marc Michel,Philippe Quittet,Jean-François Viallard,Magda Alexis,Françoise Roudot-Thoraval,Stéphane Cheze,Jean-Marc Durand,François Lefrère,Lionel Galicier,Olivier Lambotte,Gérard Panelatti,Borhane Slama,Gandhi Damaj,Gérard Sebahoun,Emmanuel Gyan,Xavier Delbrel,Nathalie Dhedin,Bruno Royer,Nicolas Schleinitz,Jean-François Rossi,Matthieu Mahévas,Laetitia Languille,Philippe Bierling,Bertrand Godeau
Immunologic effects of rituximab on the human spleen in immune thrombocytopenia
Sylvain Audia,Maxime Samson,Julien Guy,Nona Janikashvili,Jennifer Fraszczak,Malika Trad,Marion Ciudad,Vanessa Leguy,Sabine Berthier,Tony Petrella,Serge Aho-Glélé,Laurent Martin,Marc Maynadié,Bernard Lorcerie,Patrick Rat,Nicolas Cheynel,Emmanuel Katsanis,Nicolas Larmonier,Bernard Bonnotte
Red Cells, Iron, and Erythropoiesis
Thrombosis and Hemostasis
Transplantation
Outcome of AL amyloidosis after high-dose melphalan and autologous stem cell transplantation: long-term results in a series of 421 patients
Clinical Trials & Observations
Maria Teresa Cibeira,Vaishali Sanchorawala,David C. Seldin,Karen Quillen,John L. Berk,Laura M. Dember,Adam Segal,Frederick Ruberg,Hans Meier-Ewert,Nancy T. Andrea,J. Mark Sloan,Kathleen T. Finn,Gheorghe Doros,Joan Blade,Martha Skinner
Risk factors associated with increased nonrelapse mortality and with poor overall survival in children with chronic graft-versus-host disease
Clinical Trials & Observations
David A. Jacobsohn,Mukta Arora,John P. Klein,Anna Hassebroek,Mary E. Flowers,Corey S. Cutler,Alvaro Urbano-Ispizua,Brian J. Bolwell,Joseph H. Antin,Michael Boyiadzis,Jean-Yves Cahn,Mitchell S. Cairo,Roger H. Herzig,Luis M. Isola,Thomas R. Klumpp,Stephanie J. Lee,Effie W. Petersdorf,Stella Santarone,Robert P. Gale,Harry C. Schouten,Stephen R. Spellman,Daniel J. Weisdorf,John R. Wingard,Mary M. Horowitz,Steven Z. Pavletic
Correspondence
Retraction
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Cover Image
Cover Image
![issue cover]()
The image shows Dictyostelium discoideum amoebae streaming by chemotaxis to form a multicellular aggregate.Wild-type human Shwachman-Bodian-Diamond syndrome (SBDS) protein complements the growth and ribosome assembly defects in conditional SBDS null amoebae, but SBDS variants associated with Shwachman-Diamond syndrome (SDS) are defective. Extension of these findings to human cells supports the hypothesis that SDS is a ribosomopathy caused by corruption of an essential cytoplasmic step in the maturation of the large ribosomal subunit. See the article byWong et al on page 4305.
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