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SNP array–based karyotyping: differences and similarities between aplastic anemia and hypocellular myelodysplastic syndromes
Variant Philadelphia translocations: molecular-cytogenetic characterization and prognostic influence on frontline imatinib therapy, a GIMEMA Working Party on CML analysis
Overexpression of microRNA-16-2 contributes to the abnormal erythropoiesis in polycythemia vera
Serum hepcidin: reference ranges and biochemical correlates in the general population
Impact of immune modulation with anti–T-cell antibodies on the outcome of reduced-intensity allogeneic hematopoietic stem cell transplantation for hematologic malignancies
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Hematopoiesis and Stem Cells
SNP array–based karyotyping: differences and similarities between aplastic anemia and hypocellular myelodysplastic syndromes
Clinical Trials & Observations
Manuel G. Afable, II,Marcin Wlodarski,Hideki Makishima,Mohammed Shaik,Mikkael A. Sekeres,Ramon V. Tiu,Matt Kalaycio,Christine L. O'Keefe,Jaroslaw P. Maciejewski
Immunobiology
Specificity for the tumor-associated self-antigen WT1 drives the development of fully functional memory T cells in the absence of vaccination
Constandina Pospori,Shao-An Xue,Angelika Holler,Cecile Voisine,Mario Perro,Judith King,Farnaz Fallah-Arani,Barry Flutter,Ronjon Chakraverty,Hans J. Stauss,Emma C. Morris
Lymphoid Neoplasia
Genomic characterization implicates iAMP21 as a likely primary genetic event in childhood B-cell precursor acute lymphoblastic leukemia
Vikki Rand,Helen Parker,Lisa J. Russell,Claire Schwab,Hannah Ensor,Julie Irving,Lisa Jones,Dino Masic,Lynne Minto,Heather Morrison,Sarra Ryan,Hazel Robinson,Paul Sinclair,Anthony V. Moorman,Jonathan C. Strefford,Christine J. Harrison
Myeloid Neoplasia
Variant Philadelphia translocations: molecular-cytogenetic characterization and prognostic influence on frontline imatinib therapy, a GIMEMA Working Party on CML analysis
Clinical Trials & Observations
Giulia Marzocchi,Fausto Castagnetti,Simona Luatti,Carmen Baldazzi,Monica Stacchini,Gabriele Gugliotta,Marilina Amabile,Giorgina Specchia,Mario Sessarego,Ursula Giussani,Laura Valori,Giancarlo Discepoli,Anna Montaldi,Alessandra Santoro,Laura Bonaldi,Giovanni Giudici,Anna Maria Cianciulli,Francesca Giacobbi,Francesca Palandri,Fabrizio Pane,Giuseppe Saglio,Giovanni Martinelli,Michele Baccarani,Gianantonio Rosti,Nicoletta Testoni,for the Gruppo Italiano Malattie EMatologiche dell'Adulto (GIMEMA) Working Party on Chronic Myeloid Leukemia
R723, a selective JAK2 inhibitor, effectively treats JAK2V617F-induced murine myeloproliferative neoplasm
Kotaro Shide,Takuro Kameda,Vadim Markovtsov,Haruko K. Shimoda,Elizabeth Tonkin,Shuling Fang,Chian Liu,Marina Gelman,Wayne Lang,Jason Romero,John McLaughlin,Somasekhar Bhamidipati,Jeffrey Clough,Caroline Low,Andrea Reitsma,Stacey Siu,Polly Pine,Gary Park,Allan Torneros,Matt Duan,Rajinder Singh,Donald G. Payan,Takuya Matsunaga,Yasumichi Hitoshi,Kazuya Shimoda
A genome-wide association study identifies novel loci associated with susceptibility to chronic myeloid leukemia
Dong Hwan (Dennis) Kim,Seung-Tae Lee,Hong-Hee Won,Seonwoo Kim,Min-Ji Kim,Hee-Jin Kim,Sun-Hee Kim,Jong-Won Kim,Hyeoung-Joon Kim,Yeo-Kyeoung Kim,Sang Kyun Sohn,Joon Ho Moon,Chul Won Jung,Jeffrey H. Lipton
Overexpression of microRNA-16-2 contributes to the abnormal erythropoiesis in polycythemia vera
Brief Report
Paola Guglielmelli,Lorenzo Tozzi,Costanza Bogani,Ilaria Iacobucci,Vanessa Ponziani,Giovanni Martinelli,Alberto Bosi,Alessandro M. Vannucchi,on behalf of the AGIMM (AIRC-Gruppo Italiano Malattie Mieloproliferative) Investigators
Red Cells, Iron, and Erythropoiesis
Codanin-1 mutations in congenital dyserythropoietic anemia type 1 affect HP1α localization in erythroblasts
Raffaele Renella,Nigel A. Roberts,Jill M. Brown,Marco De Gobbi,Louise E. Bird,Tasneem Hassanali,Jacqueline A. Sharpe,Jacqueline Sloane-Stanley,David J. P. Ferguson,Jacqueline Cordell,Veronica J. Buckle,Douglas R. Higgs,William G. Wood
Serum hepcidin: reference ranges and biochemical correlates in the general population
e-blood
Tessel E. Galesloot,Sita H. Vermeulen,Anneke J. Geurts-Moespot,Siem M. Klaver,Joyce J. Kroot,Dorlene van Tienoven,Jack F. M. Wetzels,Lambertus A. L. M. Kiemeney,Fred C. Sweep,Martin den Heijer,Dorine W. Swinkels
Thrombosis and Hemostasis
Transplantation
Impact of immune modulation with anti–T-cell antibodies on the outcome of reduced-intensity allogeneic hematopoietic stem cell transplantation for hematologic malignancies
Clinical Trials & Observations
Robert J. Soiffer,Jennifer LeRademacher,Vincent Ho,Fangyu Kan,Andrew Artz,Richard E. Champlin,Steven Devine,Luis Isola,Hillard M. Lazarus,David I. Marks,David L. Porter,Edmund K. Waller,Mary M. Horowitz,Mary Eapen
Other Departments
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Cover Image
Cover Image
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The cover image illustrates the ultrastructural abnormalities observed in erythroid progenitors of patients with congenital dyserythropoietic anemia type 1. Two intermediate erythroblasts display the characteristic “spongy” (Swiss cheese–like) nuclear chromatin pattern and are connected by an internuclear bridge, as imaged by electron microscopy. See the article by Renella et al on page 6928.
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