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International Myeloma Working Group consensus approach to the treatment of multiple myeloma patients who are candidates for autologous stem cell transplantation
STAT3-dependent IL-21 production from T helper cells regulates hematopoietic progenitor cell homeostasis
HIV-1–related Hodgkin lymphoma in the era of combination antiretroviral therapy: incidence and evolution of CD4+ T-cell lymphocytes
Autologous stem cell transplantation as a first-line treatment strategy for chronic lymphocytic leukemia: a multicenter, randomized, controlled trial from the SFGM-TC and GFLLC
Long-term risk for subsequent leukemia after treatment for childhood cancer: a report from the Childhood Cancer Survivor Study
Incidence of factor VIII inhibitors throughout life in severe hemophilia A in the United Kingdom
Chronic graft-versus-host disease: long-term results from a randomized trial on graft-versus-host disease prophylaxis with or without anti–T-cell globulin ATG-Fresenius
Issue Archive
June 9 2011
Table of Contents
Inside Blood
Perspectives
International Myeloma Working Group consensus approach to the treatment of multiple myeloma patients who are candidates for autologous stem cell transplantation
Clinical Trials & Observations
Michele Cavo,S. Vincent Rajkumar,Antonio Palumbo,Philippe Moreau,Robert Orlowski,Joan Bladé,Orhan Sezer,Heinz Ludwig,Meletios A. Dimopoulos,Michel Attal,Pieter Sonneveld,Mario Boccadoro,Kenneth C. Anderson,Paul G. Richardson,William Bensinger,Hans E. Johnsen,Nicolaus Kroeger,Gösta Gahrton,P. Leif Bergsagel,David H. Vesole,Hermann Einsele,Sundar Jagannath,Ruben Niesvizky,Brian G. M. Durie,Jesus San Miguel,Sagar Lonial,on behalf of the International Myeloma Working Group
Review Articles
How I Treat
Hematopoiesis and Stem Cells
STAT3-dependent IL-21 production from T helper cells regulates hematopoietic progenitor cell homeostasis
Brief Report
Mark H. Kaplan,Nicole L. Glosson,Gretta L. Stritesky,Norman Yeh,John Kinzfogl,Sara L. Rohrabaugh,Ritobrata Goswami,Duy Pham,David E. Levy,Randy R. Brutkiewicz,Janice S. Blum,Scott Cooper,Giao Hangoc,Hal E. Broxmeyer
Immunobiology
Heat-shock protein 90 inhibition in autoimmunity to type VII collagen: evidence that nonmalignant plasma cells are not therapeutic targets
Michael Kasperkiewicz,Ralf Müller,Rudolf Manz,Moritz Magens,Christoph M. Hammers,Csaba Somlai,Jürgen Westermann,Enno Schmidt,Detlef Zillikens,Ralf J. Ludwig,Antal Orosz
Lymphoid Neoplasia
HIV-1–related Hodgkin lymphoma in the era of combination antiretroviral therapy: incidence and evolution of CD4+ T-cell lymphocytes
Clinical Trials & Observations
Julia Bohlius,Kurt Schmidlin,François Boué,Gerd Fätkenheuer,Margaret May,Ana Maria Caro-Murillo,Amanda Mocroft,Fabrice Bonnet,Gary Clifford,Vassilios Paparizos,Jose M. Miro,Niels Obel,Maria Prins,Geneviève Chêne,Matthias Egger,Collaboration of Observational HIV Epidemiological Research Europe
Autologous stem cell transplantation as a first-line treatment strategy for chronic lymphocytic leukemia: a multicenter, randomized, controlled trial from the SFGM-TC and GFLLC
Clinical Trials & Observations
Laurent Sutton,Sylvie Chevret,Olivier Tournilhac,Marine Diviné,Véronique Leblond,Bernadette Corront,Stéphane Leprêtre,Houchingue Eghbali,Eric Van Den Neste,Mauricette Michallet,Frédéric Maloisel,Krimo Bouabdallah,Didier Decaudin,Christian Berthou,Pauline Brice,Hugo Gonzalez,Elise Chapiro,Isabelle Radford-Weiss,Nathalie Leporrier,Karim Maloum,Florence Nguyen-Khac,Frédéric Davi,Julie Lejeune,Hélène Merle-Béral,Michel Leporrier,for the Société Française de Greffe de Moelle et de Thérapie Cellulaire (SFGM-TC) and Groupe Français d'étude de la Leucémie Lymphoïde Chronique (GFLLC)
Integrin β7-mediated regulation of multiple myeloma cell adhesion, migration, and invasion
Paola Neri,Li Ren,Abdel Kareem Azab,Matthew Brentnall,Kathy Gratton,Alexander C. Klimowicz,Charles Lin,Peter Duggan,Pierfrancesco Tassone,Adnan Mansoor,Douglas A. Stewart,Lawrence H. Boise,Irene M. Ghobrial,Nizar J. Bahlis
Combinatorial effects of microRNAs to suppress the Myc oncogenic pathway
María J. Bueno,Marta Gómez de Cedrón,Gonzalo Gómez-López,Ignacio Pérez de Castro,Lorena Di Lisio,Santiago Montes-Moreno,Nerea Martínez,Manuel Guerrero,Ruth Sánchez-Martínez,Javier Santos,David G. Pisano,Miguel Angel Piris,José Fernández-Piqueras,Marcos Malumbres
Bruton tyrosine kinase represents a promising therapeutic target for treatment of chronic lymphocytic leukemia and is effectively targeted by PCI-32765
Sarah E. M. Herman,Amber L. Gordon,Erin Hertlein,Asha Ramanunni,Xiaoli Zhang,Samantha Jaglowski,Joseph Flynn,Jeffrey Jones,Kristie A. Blum,Joseph J. Buggy,Ahmed Hamdy,Amy J. Johnson,John C. Byrd
Myeloid Neoplasia
Long-term risk for subsequent leukemia after treatment for childhood cancer: a report from the Childhood Cancer Survivor Study
Brief Report
Kerri Nottage,Jennifer Lanctot,Zhenghong Li,Joseph P. Neglia,Smita Bhatia,Sue Hammond,Wendy Leisenring,Anna Meadows,Deokumar Srivastava,Leslie L. Robison,Gregory T. Armstrong
Platelets and Thrombopoiesis
Red Cells, Iron, and Erythropoiesis
Thrombosis and Hemostasis
The development of inflammatory joint disease is attenuated in mice expressing the anticoagulant prothrombin mutant W215A/E217A
Matthew J. Flick,Anil K. Chauhan,Malinda Frederick,Kathryn E. Talmage,Keith W. Kombrinck,Whitney Miller,Eric S. Mullins,Joseph S. Palumbo,Xunzhen Zheng,Naomi L. Esmon,Charles T. Esmon,Sherry Thornton,Ann Becker,Leslie A. Pelc,Enrico Di Cera,Denisa D. Wagner,Jay L. Degen
Incidence of factor VIII inhibitors throughout life in severe hemophilia A in the United Kingdom
Brief Report
Charles R.M. Hay,Ben Palmer,Elizabeth Chalmers,Ri Liesner,Rhona Maclean,Savita Rangarajan,Michael Williams,Peter W. Collins,on behalf of United Kingdom Haemophilia Centre Doctors' Organisation (UKHCDO)
Transplantation
Chronic graft-versus-host disease: long-term results from a randomized trial on graft-versus-host disease prophylaxis with or without anti–T-cell globulin ATG-Fresenius
Clinical Trials & Observations
Gérard Socié,Claudia Schmoor,Wolfgang A. Bethge,Hellmut D. Ottinger,Matthias Stelljes,Axel R. Zander,Liisa Volin,Tapani Ruutu,Dominik A. Heim,Rainer Schwerdtfeger,Karin Kolbe,Jiri Mayer,Johan A. Maertens,Werner Linkesch,Ernst Holler,Vladimir Koza,Martin Bornhäuser,Hermann Einsele,Hans-Jochem Kolb,Hartmut Bertz,Matthias Egger,Olga Grishina,Jürgen Finke,for the ATG-Fresenius Trial Group
Vascular Biology
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Cover Image
Cover Image
![issue cover]()
The cover image shows how maternal IgG antibodies inhibit B-cell responses by cross-linking the B-cell receptor (BCR; membrane-bound Ig in green in the center) with the inhibitory Fc receptor (FcγRIIB; in brown on the left) through a measles vaccine virus–IgG complex. This inhibition can be partially overcome by cross-linking the B-cell receptor with the stimulatory complement receptor 2 (CD21/CD19/CD81/Leu-13; in green and blue to the right) through a measles vaccine virus–IgM (pentameter in purple)–complement C3d protein (orange) complex. (Illustration by Tim Vojt, Medical Illustrator, The Ohio State University.) See the full article by Kim et al on page 6143.
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