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Fludarabine, cyclophosphamide, and rituximab chemoimmunotherapy is highly effective treatment for relapsed patients with CLL
Complete response correlates with long-term progression-free and overall survival in elderly myeloma treated with novel agents: analysis of 1175 patients
Identification of microRNAs in the cerebrospinal fluid as marker for primary diffuse large B-cell lymphoma of the central nervous system
SNP rs6457327 in the HLA region on chromosome 6p is predictive of the transformation of follicular lymphoma
Imatinib mesylate versus allogeneic hematopoietic stem cell transplantation for patients with chronic myelogenous leukemia in the accelerated phase
Mixed-phenotype acute leukemia: clinical and laboratory features and outcome in 100 patients defined according to the WHO 2008 classification
Achievement of VGPR to induction therapy is an important prognostic factor for longer PFS in the IFM 2005-01 trial
Comparative analysis of risk factors for acute graft-versus-host disease and for chronic graft-versus-host disease according to National Institutes of Health consensus criteria
Successful sustained engraftment after reduced-intensity umbilical cord blood transplantation for adult patients with severe aplastic anemia
Issue Archive
March 17 2011
In this Issue
Table of Contents
Inside Blood
Blood Work
Perspectives
How I Treat
Clinical Trials and Observations
Fludarabine, cyclophosphamide, and rituximab chemoimmunotherapy is highly effective treatment for relapsed patients with CLL
Clinical Trials & Observations
Xavier C. Badoux,Michael J. Keating,Xuemei Wang,Susan M. O'Brien,Alessandra Ferrajoli,Stefan Faderl,Jan Burger,Charles Koller,Susan Lerner,Hagop Kantarjian,William G. Wierda
Complete response correlates with long-term progression-free and overall survival in elderly myeloma treated with novel agents: analysis of 1175 patients
Clinical Trials & Observations
Francesca Gay,Alessandra Larocca,Pierre Wijermans,Federica Cavallo,Davide Rossi,Ron Schaafsma,Mariella Genuardi,Alessandra Romano,Anna Marina Liberati,Agostina Siniscalchi,Maria T. Petrucci,Chiara Nozzoli,Francesca Patriarca,Massimo Offidani,Roberto Ria,Paola Omedè,Benedetto Bruno,Roberto Passera,Pellegrino Musto,Mario Boccadoro,Pieter Sonneveld,Antonio Palumbo
Identification of microRNAs in the cerebrospinal fluid as marker for primary diffuse large B-cell lymphoma of the central nervous system
Clinical Trials & Observations
Alexander Baraniskin,Jan Kuhnhenn,Uwe Schlegel,Andrew Chan,Martina Deckert,Ralf Gold,Abdelouahid Maghnouj,Hannah Zöllner,Anke Reinacher-Schick,Wolff Schmiegel,Stephan A. Hahn,Roland Schroers
Gene Therapy
Hematopoiesis and Stem Cells
Immunobiology
Lymphoid Neoplasia
SNP rs6457327 in the HLA region on chromosome 6p is predictive of the transformation of follicular lymphoma
Brief Report
David Wrench,Pamela Leighton,Christine F. Skibola,Lucia Conde,Jean-Baptiste Cazier,Janet Matthews,Sameena Iqbal,Emanuela Carlotti,Csaba Bödör,Silvia Montoto,Maria Calaminici,John G. Gribben,T. Andrew Lister,Jude Fitzgibbon
Myeloid Neoplasia
Imatinib mesylate versus allogeneic hematopoietic stem cell transplantation for patients with chronic myelogenous leukemia in the accelerated phase
Clinical Trials & Observations
Qian Jiang,Lan-Ping Xu,Dai-Hong Liu,Kai-Yan Liu,Shan-Shan Chen,Bin Jiang,Hao Jiang,Huan Chen,Yu-Hong Chen,Wei Han,Xiao-Hui Zhang,Yu Wang,Ya-Zhen Qin,Yan-Rong Liu,Yue-Yun Lai,Xiao-Jun Huang
Mixed-phenotype acute leukemia: clinical and laboratory features and outcome in 100 patients defined according to the WHO 2008 classification
Clinical Trials & Observations
Estella Matutes,Winfried F. Pickl,Mars van't Veer,Ricardo Morilla,John Swansbury,Herbert Strobl,Andishe Attarbaschi,Georg Hopfinger,Sue Ashley,Marie Christine Bene,Anna Porwit,Alberto Orfao,Petr Lemez,Richard Schabath,Wolf-Dieter Ludwig
Phagocytes, Granulocytes, and Myelopoiesis
Monocytic cells derived from human embryonic stem cells and fetal liver share common differentiation pathways and homeostatic functions
Olena Klimchenko,Antonio Di Stefano,Birgit Geoerger,Sofiane Hamidi,Paule Opolon,Thomas Robert,Mélanie Routhier,Jamel El-Benna,Anne-Lise Delezoide,Siham Boukour,Bernadette Lescure,Eric Solary,William Vainchenker,Françoise Norol
Platelets and Thrombopoiesis
Thrombosis and Hemostasis
Transplantation
Achievement of VGPR to induction therapy is an important prognostic factor for longer PFS in the IFM 2005-01 trial
Brief Report
Philippe Moreau,Michel Attal,Brigitte Pégourié,Lucie Planche,Cyrille Hulin,Thierry Facon,Anne-Marie Stoppa,Jean-Gabriel Fuzibet,Bernard Grosbois,Chantal Doyen,Nicolas Ketterer,Catherine Sebban,Brigitte Kolb,Carine Chaleteix,Mamoun Dib,Laurent Voillat,Jean Fontan,Laurent Garderet,Jérôme Jaubert,Claire Mathiot,Dixie Esseltine,Hervé Avet-Loiseau,Jean-Luc Harousseau,for the IFM 2005-01 study investigators*
Comparative analysis of risk factors for acute graft-versus-host disease and for chronic graft-versus-host disease according to National Institutes of Health consensus criteria
Clinical Trials & Observations
Mary E. D. Flowers,Yoshihiro Inamoto,Paul A. Carpenter,Stephanie J. Lee,Hans-Peter Kiem,Effie W. Petersdorf,Shalini E. Pereira,Richard A. Nash,Marco Mielcarek,Matthew L. Fero,Edus H. Warren,Jean E. Sanders,Rainer F. Storb,Frederick R. Appelbaum,Barry E. Storer,Paul J. Martin
Successful sustained engraftment after reduced-intensity umbilical cord blood transplantation for adult patients with severe aplastic anemia
Brief Report
Hisashi Yamamoto,Daisuke Kato,Naoyuki Uchida,Kazuya Ishiwata,Hideki Araoka,Shinsuke Takagi,Nobuaki Nakano,Masanori Tsuji,Yuki Asano-Mori,Naofumi Matsuno,Kazuhiro Masuoka,Koji Izutsu,Atsushi Wake,Akiko Yoneyama,Shigeyoshi Makino,Shuichi Taniguchi
Vascular Biology
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Cover Image
Cover Image
![issue cover]()
The cover image shows two baby hamster kidney–derived (BHK) cells expressing the hemophilia A–associated factor VIII A3 domain mutant N1922S (top) and 2 BHK cells expressing wild-type factor VIII (bottom). Factor VIII is detected with an anti–factor VIII murine monoclonal antibody, 2-54, and DyLight 488 donkey anti–mouse antibody (pseudocolored green). The Golgi apparatus is localized using wheat germ agglutinin–Alexa Fluor 350 conjugate (pseudocolored red). Nuclei are stained with DRAQ5 (pseudocolored blue). Factor VIII colocalizes with Golgi in wild-type cells (red-green overlap, yellow), but not in N1922S cells, demonstrating a block in transport of N1922S factor VIII from the endoplasmic reticulum to Golgi. The cover image is a montage of individual cell images now artificially grouped together. See the article by Summers et al on page 3190.
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