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Phase 1/2 trial of total marrow and lymph node irradiation to augment reduced-intensity transplantation for advanced hematologic malignancies
X-linked lymphoproliferative disease due to SAP/SH2D1A deficiency: a multicenter study on the manifestations, management and outcome of the disease
Transfer of influenza vaccine–primed costimulated autologous T cells after stem cell transplantation for multiple myeloma leads to reconstitution of influenza immunity: results of a randomized clinical trial
A novel NUP98/RARG gene fusion in acute myeloid leukemia resembling acute promyelocytic leukemia
Thrombospondin-1 is not the major activator of TGF-β1 in thrombopoietin-induced myelofibrosis
Issue Archive
January 6 2011
In this Issue
Table of Contents
Inside blood
Blood Work
Plenary paper
PLATELETS AND THROMBOPOIESIS
Intracoronary shear-related up-regulation of platelet P-selectin and platelet-monocyte aggregation despite the use of aspirin and clopidogrel
Andy S. C. Yong,Gabrielle J. Pennings,Michael Chang,Afiqah Hamzah,Tommy Chung,Miao Qi,David Brieger,Masud Behnia,Steven A. Krilis,Martin K.C. Ng,Harry C. Lowe,Leonard Kritharides
Perspectives
Remuneration of hematopoietic stem cell donors: principles and perspective of the World Marrow Donor Association
Michael Boo,Suzanna M. van Walraven,Jeremy Chapman,Brian Lindberg,Alexander H. Schmidt,Bronwen E. Shaw,Galen E. Switzer,Edward Yang,Torstein Egeland,on behalf of the World Marrow Donor Association
Review Article
How I treat
Clinical Trials and Observations
Phase 1/2 trial of total marrow and lymph node irradiation to augment reduced-intensity transplantation for advanced hematologic malignancies
Clinical Trials & Observations
Joseph Rosenthal,Jeffrey Wong,Anthony Stein,Dajun Qian,Debbie Hitt,Hossameldin Naeem,Andrew Dagis,Sandra H. Thomas,Stephen Forman
Gene therapy
Hematopoiesis and Stem Cells
Immunobiology
X-linked lymphoproliferative disease due to SAP/SH2D1A deficiency: a multicenter study on the manifestations, management and outcome of the disease
Clinical Trials & Observations
Claire Booth,Kimberly C. Gilmour,Paul Veys,Andrew R. Gennery,Mary A. Slatter,Helen Chapel,Paul T. Heath,Colin G. Steward,Owen Smith,Anna O'Meara,Hilary Kerrigan,Nizar Mahlaoui,Marina Cavazzana-Calvo,Alain Fischer,Despina Moshous,Stephane Blanche,Jana Pachlopnik Schmid,Sylvain Latour,Genevieve de Saint-Basile,Michael Albert,Gundula Notheis,Nikolaus Rieber,Brigitte Strahm,Henrike Ritterbusch,Arjan Lankester,Nico G. Hartwig,Isabelle Meyts,Alessandro Plebani,Annarosa Soresina,Andrea Finocchi,Claudio Pignata,Emilia Cirillo,Sonia Bonanomi,Christina Peters,Krzysztof Kalwak,Srdjan Pasic,Petr Sedlacek,Janez Jazbec,Hirokazu Kanegane,Kim E. Nichols,I. Celine Hanson,Neena Kapoor,Elie Haddad,Morton Cowan,Sharon Choo,Joanne Smart,Peter D. Arkwright,Hubert B. Gaspar
Transfer of influenza vaccine–primed costimulated autologous T cells after stem cell transplantation for multiple myeloma leads to reconstitution of influenza immunity: results of a randomized clinical trial
Clinical Trials & Observations
Edward A. Stadtmauer,Dan T. Vogl,Eline Luning Prak,Jean Boyer,Nicole A. Aqui,Aaron P. Rapoport,Kenyetta R. McDonald,Xiaoling Hou,Heather Murphy,Rita Bhagat,Patricia A. Mangan,Anne Chew,Elizabeth A. Veloso,Bruce L. Levine,Robert H. Vonderheide,Abbas F. Jawad,Carl H. June,Kathleen E. Sullivan
Notch2 signaling is required for proper mast cell distribution and mucosal immunity in the intestine
Mamiko Sakata-Yanagimoto,Toru Sakai,Yasuyuki Miyake,Toshiki I. Saito,Haruhiko Maruyama,Yasuyuki Morishita,Etsuko Nakagami-Yamaguchi,Keiki Kumano,Hideo Yagita,Masashi Fukayama,Seishi Ogawa,Mineo Kurokawa,Koji Yasutomo,Shigeru Chiba
High expression levels of B lymphocyte stimulator (BLyS) by dendritic cells correlate with HIV-related B-cell disease progression in humans
Julie Fontaine,Josiane Chagnon-Choquet,Han Sang Valcke,Johanne Poudrier,Michel Roger,the Montreal Primary HIV Infection and Long-Term Non-Progressor Study Groups
Lymphoid Neoplasia
STAT6 signaling pathway activated by the cytokines IL-4 and IL-13 induces expression of the Epstein-Barr virus–encoded protein LMP-1 in absence of EBNA-2: implications for the type II EBV latent gene expression in Hodgkin lymphoma
Loránd L. Kis,Natalija Gerasimčik,Daniel Salamon,Emma K. Persson,Noémi Nagy,George Klein,Eva Severinson,Eva Klein
Constitutive BR3 receptor signaling in diffuse, large B-cell lymphomas stabilizes nuclear factor-κB–inducing kinase while activating both canonical and alternative nuclear factor-κB pathways
Lan V. Pham,Lingchen Fu,Archito T. Tamayo,Carlos Bueso-Ramos,Elias Drakos,Francisco Vega,L. Jeffrey Medeiros,Richard J. Ford
The MMSET histone methyl transferase switches global histone methylation and alters gene expression in t(4;14) multiple myeloma cells
Eva Martinez-Garcia,Relja Popovic,Dong-Joon Min,Steve M. M. Sweet,Paul M. Thomas,Leonid Zamdborg,Aaron Heffner,Christine Will,Laurence Lamy,Louis M. Staudt,David L. Levens,Neil L. Kelleher,Jonathan D. Licht
Myeloid Neoplasia
Two types of C/EBPα mutations play distinct but collaborative roles in leukemogenesis: lessons from clinical data and BMT models
Naoko Kato,Jiro Kitaura,Noriko Doki,Yukiko Komeno,Naoko Watanabe-Okochi,Katsuhiro Togami,Fumio Nakahara,Toshihiko Oki,Yutaka Enomoto,Yumi Fukuchi,Hideaki Nakajima,Yuka Harada,Hironori Harada,Toshio Kitamura
A novel NUP98/RARG gene fusion in acute myeloid leukemia resembling acute promyelocytic leukemia
Brief Report
Esperanza Such,José Cervera,Ana Valencia,Eva Barragán,Mariam Ibañez,Irene Luna,Óscar Fuster,Maria Luz Perez-Sirvent,Leonor Senent,Amparo Sempere,Jesús Martinez,Guillermo Martín-Aragonés,Miguel A. Sanz
Thrombospondin-1 is not the major activator of TGF-β1 in thrombopoietin-induced myelofibrosis
Brief Report
Solène Evrard,Olivier Bluteau,Micheline Tulliez,Philippe Rameau,Patrick Gonin,Eva Zetterberg,Jan Palmblad,Arnaud Bonnefoy,Jean-Luc Villeval,William Vainchenker,Stéphane Giraudier,Orianne Wagner-Ballon
Phagocytes, Granulocytes, and Myelopoiesis
Platelets and Thrombopoiesis
Thrombosis and Hemostasis
Association of genomic loci from a cardiovascular gene SNP array with fibrinogen levels in European Americans and African-Americans from six cohort studies: the Candidate Gene Association Resource (CARe)
Christina L. Wassel,Leslie A. Lange,Brendan J. Keating,Kira C. Taylor,Andrew D. Johnson,Cameron Palmer,Lindsey A. Ho,Nicholas L. Smith,Ethan M. Lange,Yun Li,Qiong Yang,Joseph A. Delaney,Weihong Tang,Geoffrey Tofler,Susan Redline,Herman A. Taylor, Jr,James G. Wilson,Russell P. Tracy,David R. Jacobs, Jr,Aaron R. Folsom,David Green,Christopher J. O'Donnell,Alexander P. Reiner
Transplantation
Notch signaling is a critical regulator of allogeneic CD4+ T-cell responses mediating graft-versus-host disease
Yi Zhang,Ashley R. Sandy,Jina Wang,Vedran Radojcic,Gloria T. Shan,Ivy T. Tran,Ann Friedman,Koji Kato,Shan He,Shuaiying Cui,Elizabeth Hexner,Dale M. Frank,Stephen G. Emerson,Warren S. Pear,Ivan Maillard
Vascular Biology
Correspondence
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Cover Image
Cover Image
Acute myeloid leukemia with a novel NUP98/RARG rearrangement displaying morphologic features, resembling the classical hypergranular subtype of acute promyelocytic leukemia. The cover image illustrates a May-Grünwald-Giemsa–stained bone marrow smear showing the presence of promyelocytes with hypergranulated cytoplasm and bundles of Auer rods (faggot cell). See the article by Such et al on page 242.
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