Skip to Main Content

Advertisement intended for health care professionals

Umbrella Alt Text
Cart
header search
Search
Skip Nav Destination

Issue Archive

Volume 116, Issue 8
August 26 2010
Issue Cover

Table of Contents

Inside Blood

CLINICAL TRIALS
PIDs and cancer: an evolving story
Luigi D. Notarangelo
View Articletitled, PIDs and cancer: an evolving story
IMMUNOBIOLOGY
A new window on c-Myb function
Timothy P. Bender
View Articletitled, A new window on c-Myb function
MYELOID NEOPLASIA
Remission in CML: is DNA useful?
François-Xavier Mahon
View Articletitled, Remission in CML: is DNA useful?
THROMBOSIS & HEMOSTASIS
A snappy new concept for APS
Jacob H. Rand
View Articletitled, A snappy new concept for APS
VASCULAR BIOLOGY
PLDing a case for angiogenesis
Anne Hamik,Mukesh K. Jain
View Articletitled, PLDing a case for angiogenesis

Review Article

Dyslipidemia after allogeneic hematopoietic stem cell transplantation: evaluation and management
Clinical Trials & Observations
Michelle L. Griffith,Bipin N. Savani,Jeffrey B. Boord
View Articletitled, Dyslipidemia after allogeneic hematopoietic stem cell transplantation: evaluation and management

Clinical Trials and Observations

Observation versus antiplatelet therapy as primary prophylaxis for thrombosis in low-risk essential thrombocythemia
CME
Alberto Alvarez-Larrán,Francisco Cervantes,Arturo Pereira,Eduardo Arellano-Rodrigo,Virginia Pérez-Andreu,Juan-Carlos Hernández-Boluda,Ramón Ayats,Carlos Salvador,Ana Muntañola,Beatriz Bellosillo,Vicente Vicente,Luis Hernández-Nieto,Carmen Burgaleta,Blanca Xicoy,Carlos Besses
View Articletitled, Observation versus antiplatelet therapy as primary prophylaxis for thrombosis in low-risk essential thrombocythemia

Gene Therapy

Factor IX ectopically expressed in platelets can be stored in α-granules and corrects the phenotype of hemophilia B mice
Guowei Zhang,Qizhen Shi,Scot A. Fahs,Erin L. Kuether,Christopher E. Walsh,Robert R. Montgomery
View Articletitled, Factor IX ectopically expressed in platelets can be stored in α-granules and corrects the phenotype of hemophilia B mice
Supplemental data

Hematopoiesis and Stem Cells

A major role of TGF-β1 in the homing capacities of murine hematopoietic stem cell/progenitors
Claude Capron,Catherine Lacout,Yann Lécluse,Valérie Jalbert,Hédia Chagraoui,Sabine Charrier,Anne Galy,Annelise Bennaceur-Griscelli,Elisabeth Cramer-Bordé,William Vainchenker
View Articletitled, A major role of TGF-β1 in the homing capacities of murine hematopoietic stem cell/progenitors
Supplemental data
The homeobox gene Hhex regulates the earliest stages of definitive hematopoiesis
Helicia Paz,Maureen R. Lynch,Clifford W. Bogue,Judith C. Gasson
View Articletitled, The homeobox gene <em>Hhex</em> regulates the earliest stages of definitive hematopoiesis
Supplemental data
In search of the original leukemic clone in chronic myeloid leukemia patients in complete molecular remission after stem cell transplantation or imatinib
Clinical Trials & Observations
Manuel Sobrinho-Simões,Vicki Wilczek,Joannah Score,Nicholas C. P. Cross,Jane F. Apperley,Junia V. Melo
View Articletitled, In search of the original leukemic clone in chronic myeloid leukemia patients in complete molecular remission after stem cell transplantation or imatinib
Supplemental data

Immunobiology

Are antibody deficiency disorders associated with a narrower range of cancers than other forms of immunodeficiency?
Clinical Trials & Observations
Claire M. Vajdic,Limin Mao,Marina T. van Leeuwen,Philippa Kirkpatrick,Andrew E. Grulich,Sean Riminton
View Articletitled, Are antibody deficiency disorders associated with a narrower range of cancers than other forms of immunodeficiency?
Supplemental data
Hypomorphic Rag mutations can cause destructive midline granulomatous disease
Suk See De Ravin,Edward W. Cowen,Kol A. Zarember,Narda L. Whiting-Theobald,Douglas B. Kuhns,Netanya G. Sandler,Daniel C. Douek,Stefania Pittaluga,Pietro L. Poliani,Yu Nee Lee,Luigi D. Notarangelo,Lei Wang,Frederick W. Alt,Elizabeth M. Kang,Joshua D. Milner,Julie E. Niemela,Mary Fontana-Penn,Sara H. Sinal,Harry L. Malech
View Articletitled, Hypomorphic Rag mutations can cause destructive midline granulomatous disease
Elucidation of the integrin LFA-1–mediated signaling pathway of actin polarization in natural killer cells
Emily M. Mace,Jinyi Zhang,Katherine A. Siminovitch,Fumio Takei
View Articletitled, Elucidation of the integrin LFA-1–mediated signaling pathway of actin polarization in natural killer cells
Supplemental data
c-Myb, Menin, GATA-3, and MLL form a dynamic transcription complex that plays a pivotal role in human T helper type 2 cell development
Yuji Nakata,Anne C. Brignier,Shenghao Jin,Yuan Shen,Stephen I. Rudnick,Mayumi Sugita,Alan M. Gewirtz
View Articletitled, c-Myb, Menin, GATA-3, and MLL form a dynamic transcription complex that plays a pivotal role in human T helper type 2 cell development
Supplemental data
B7-H1/CD80 interaction is required for the induction and maintenance of peripheral T-cell tolerance
Jang-June Park,Ryusuke Omiya,Yumiko Matsumura,Yukimi Sakoda,Atsuo Kuramasu,Mathew M. Augustine,Sheng Yao,Fumihiko Tsushima,Hidehiko Narazaki,Sudarshan Anand,Yingjia Liu,Scott E. Strome,Lieping Chen,Koji Tamada
View Articletitled, B7-H1/CD80 interaction is required for the induction and maintenance of peripheral T-cell tolerance
Supplemental data
CD62L expression identifies a unique subset of polyfunctional CD56dim NK cells
Kerstin Juelke,Monica Killig,Merlin Luetke-Eversloh,Eliana Parente,Joachim Gruen,Barbara Morandi,Guido Ferlazzo,Andreas Thiel,Isabela Schmitt-Knosalla,Chiara Romagnani
View Articletitled, CD62L expression identifies a unique subset of polyfunctional CD56<sup>dim</sup> NK cells
Supplemental data

Lymphoid Neoplasia

Human T-cell leukemia virus type I (HTLV-1) proviral load and disease progression in asymptomatic HTLV-1 carriers: a nationwide prospective study in Japan
Clinical Trials & Observations
Masako Iwanaga,Toshiki Watanabe,Atae Utsunomiya,Akihiko Okayama,Kaoru Uchimaru,Ki-Ryang Koh,Masao Ogata,Hiroshi Kikuchi,Yasuko Sagara,Kimiharu Uozumi,Manabu Mochizuki,Kunihiro Tsukasaki,Yoshio Saburi,Masaomi Yamamura,Junji Tanaka,Yukiyoshi Moriuchi,Shigeo Hino,Shimeru Kamihira,Kazunari Yamaguchi,for the Joint Study on Predisposing Factors of ATL Development investigators
View Articletitled, Human T-cell leukemia virus type I (HTLV-1) proviral load and disease progression in asymptomatic HTLV-1 carriers: a nationwide prospective study in Japan
Supplemental data
Total Therapy 3 for multiple myeloma: prognostic implications of cumulative dosing and premature discontinuation of VTD maintenance components, bortezomib, thalidomide, and dexamethasone, relevant to all phases of therapy
Clinical Trials & Observations
Frits van Rhee,Jackie Szymonifka,Elias Anaissie,Bijay Nair,Sarah Waheed,Yazan Alsayed,Nathan Petty,John D. Shaughnessy, Jr,Antje Hoering,John Crowley,Bart Barlogie
View Articletitled, Total Therapy 3 for multiple myeloma: prognostic implications of cumulative dosing and premature discontinuation of VTD maintenance components, bortezomib, thalidomide, and dexamethasone, relevant to all phases of therapy
Deregulation of the telomerase reverse transcriptase (TERT) gene by chromosomal translocations in B-cell malignancies
Brief Report
Inga Nagel,Monika Szczepanowski,José I. Martín-Subero,Lana Harder,Takashi Akasaka,Ole Ammerpohl,Evelyne Callet-Bauchu,Randy D. Gascoyne,Stefan Gesk,Doug Horsman,Wolfram Klapper,Aneela Majid,José A. Martinez-Climent,Stephan Stilgenbauer,Holger Tönnies,Martin J. S. Dyer,Reiner Siebert
View Articletitled, Deregulation of the telomerase reverse transcriptase (<em>TERT</em>) gene by chromosomal translocations in B-cell malignancies
Supplemental data
A molecular risk score based on 4 functional pathways for advanced classical Hodgkin lymphoma
e-blood
Beatriz Sánchez-Espiridión,Carlos Montalbán,Ángel López,Javier Menárguez,Pilar Sabín,Carmen Ruiz-Marcellán,Andrés Lopez,Rafael Ramos,Jose Rodríguez,Araceli Cánovas,Carmen Camarero,Miguel Canales,Javier Alves,Reyes Arranz,Agustín Acevedo,Antonio Salar,Sergio Serrano,Águeda Bas,Jose M. Moraleda,Pedro Sánchez-Godoy,Fernando Burgos,Concepción Rayón,Manuel F. Fresno,José García Laraña,Mónica García-Cosío,Carlos Santonja,Jose L. López,Marta Llanos,Manuela Mollejo,Joaquín González-Carrero,Ana Marín,Jerónimo Forteza,Ramón García-Sanz,Jose F. Tomás,Manuel M. Morente,Miguel A. Piris,Juan F. García,on behalf of the Spanish Hodgkin Lymphoma Study Group
View Articletitled, A molecular risk score based on 4 functional pathways for advanced classical Hodgkin lymphoma

Myeloid Neoplasia

Differential ability of Tribbles family members to promote degradation of C/EBPα and induce acute myelogenous leukemia
Priya H. Dedhia,Karen Keeshan,Sacha Uljon,Lanwei Xu,Maria E. Vega,Olga Shestova,Meirav Zaks-Zilberman,Candice Romany,Stephen C. Blacklow,Warren S. Pear
View Articletitled, Differential ability of Tribbles family members to promote degradation of C/EBPα and induce acute myelogenous leukemia
Supplemental data

Phagocytes, Granulocytes, and Myelopoiesis

Cytokine-activated NK cells inhibit PMN apoptosis and preserve their functional capacity
Nupur Bhatnagar,Henoch S. Hong,Jayendra K. Krishnaswamy,Arash Haghikia,Georg M. Behrens,Reinhold E. Schmidt,Roland Jacobs
View Articletitled, Cytokine-activated NK cells inhibit PMN apoptosis and preserve their functional capacity
Supplemental data

Thrombosis and Hemostasis

β2-Glycoprotein I can exist in 2 conformations: implications for our understanding of the antiphospholipid syndrome
Çetin Ağar,Gwendolyn M. A. van Os,Matthias Mörgelin,Richard R. Sprenger,J. Arnoud Marquart,Rolf T. Urbanus,Ronald H. W. M. Derksen,Joost C. M. Meijers,Philip G. de Groot
View Articletitled, β<sub>2</sub>-Glycoprotein I can exist in 2 conformations: implications for our understanding of the antiphospholipid syndrome
The Kunitz-3 domain of TFPI-α is required for protein S–dependent enhancement of factor Xa inhibition
Matthew Ndonwi,Elodee A. Tuley,George J. Broze, Jr
View Articletitled, The Kunitz-3 domain of TFPI-α is required for protein S–dependent enhancement of factor Xa inhibition
Building better fibrin knob mimics: an investigation of synthetic fibrin knob peptide structures in solution and their dynamic binding with fibrinogen/fibrin holes
Sarah E. Stabenfeldt,J. Jared Gossett,Thomas H. Barker
View Articletitled, Building better fibrin knob mimics: an investigation of synthetic fibrin knob peptide structures in solution and their dynamic binding with fibrinogen/fibrin holes
Supplemental data

Transfusion Medicine

Supernatant of stored platelets causes lung inflammation and coagulopathy in a novel in vivo transfusion model
Alexander P. J. Vlaar,Jorrit J. Hofstra,Wim Kulik,Henk van Lenthe,Rienk Nieuwland,Marcus J. Schultz,Marcel M. Levi,Joris J. T. H. Roelofs,Anton T. J. Tool,Dirk de Korte,Nicole P. Juffermans
View Articletitled, Supernatant of stored platelets causes lung inflammation and coagulopathy in a novel in vivo transfusion model

Transplantation

Transplantation of allogeneic hematopoietic stem cells for adult T-cell leukemia: a nationwide retrospective study
Clinical Trials & Observations
Masakatsu Hishizawa,Junya Kanda,Atae Utsunomiya,Shuichi Taniguchi,Tetsuya Eto,Yukiyoshi Moriuchi,Ryuji Tanosaki,Fumio Kawano,Yasushi Miyazaki,Masato Masuda,Koji Nagafuji,Masamichi Hara,Minoko Takanashi,Shunro Kai,Yoshiko Atsuta,Ritsuro Suzuki,Takakazu Kawase,Keitaro Matsuo,Tokiko Nagamura-Inoue,Shunichi Kato,Hisashi Sakamaki,Yasuo Morishima,Jun Okamura,Tatsuo Ichinohe,Takashi Uchiyama
View Articletitled, Transplantation of allogeneic hematopoietic stem cells for adult T-cell leukemia: a nationwide retrospective study
Supplemental data

Vascular Biology

PLD1-dependent PKCγ activation downstream to Src is essential for the development of pathologic retinal neovascularization
Qiuhua Zhang,Dong Wang,Venkatesh Kundumani-Sridharan,Laxmisilpa Gadiparthi,Dianna A. Johnson,Gabor J. Tigyi,Gadiparthi N. Rao
View Articletitled, PLD1-dependent PKCγ activation downstream to Src is essential for the development of pathologic retinal neovascularization

Retractions

Sawada S, Ishikawa C, Tanji H, Nakachi S, Senba M, Okudaira T, Uchihara J-N, Taira N, Ohshiro K, Yamada Y, Tanaka Y, Uezato H, Ohshima K, Sasai K, Burgering BMT, Duc Dodon M, Fujii M, Sunakawa H, Mori N. Overexpression of caveolin-1 in adult T-cell leukemia. Blood. 2010; 115(11):2220–2230.
View Articletitled, Sawada S, Ishikawa C, Tanji H, Nakachi S, Senba M, Okudaira T, Uchihara J-N, Taira N, Ohshiro K, Yamada Y, Tanaka Y, Uezato H, Ohshima K, Sasai K, Burgering BMT, Duc Dodon M, Fujii M, Sunakawa H, Mori N. Overexpression of caveolin-1 in adult T-cell leukemia. <em>Blood.</em> 2010; 115(11):<span class="related-article">2220–2230</span>.
Tanji H, Ishikawa C, Sawada S, Nakachi S, Takamatsu R, Matsuda T, Okudaira T, Uchihara J-N, Ohshiro K, Tanaka Y, Senba M, Uezato H, Ohshima K, Duc Dodon M, Wu K-J, Mori N. Aberrant expression of the transcription factor Twist in adult T-cell leukemia [published online ahead of print January 13, 2010]. Blood. doi:10.1182/blood-2009-07-232231.
View Articletitled, Tanji H, Ishikawa C, Sawada S, Nakachi S, Takamatsu R, Matsuda T, Okudaira T, Uchihara J-N, Ohshiro K, Tanaka Y, Senba M, Uezato H, Ohshima K, Duc Dodon M, Wu K-J, Mori N. Aberrant expression of the transcription factor Twist in adult T-cell leukemia [published online ahead of print January 13, 2010]. <em>Blood</em>. doi:10.1182/blood-2009-07-232231.

Other Departments

Continuing Medical Education (CME) questions: Essential thrombocythemia
CME
View Articletitled, Continuing Medical Education (CME) questions: Essential thrombocythemia
All Issues

Advertisement intended for health care professionals

Baseline Immune State and T-cell Clonal Kinetics are Associated with Durable Response to CAR-T Therapy in Large B-cell Lymphoma
Allogeneic Hematopoietic Cell Transplantation for Acute Myeloid Leukemia in Adults over 70 years old
TCR targeting hematopoiesis to cure leukemia
TP53-Mutated Acute Myeloid Leukemia: How Can We Improve Outcomes?
Incorporation of immunotherapy into frontline treatment for adults with B-cell precursor acute lymphoblastic leukemia.

Advertisement intended for health care professionals

Advertisement intended for health care professionals

  • American Society of Hematology
  • 2021 L Street NW, Suite 900
  • Washington, DC 20036
  • TEL +1 202-776-0544
  • FAX +1 202-776-0545

ASH Publications

American Society of Hematology

Copyright 2024 by American Society of Hematology
 
Close Modal
This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal

Advertisement intended for health care professionals