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Efficacy and safety of once-weekly bortezomib in multiple myeloma patients
Immunoblastic morphology but not the immunohistochemical GCB/nonGCB classifier predicts outcome in diffuse large B-cell lymphoma in the RICOVER-60 trial of the DSHNHL
Defect of plasmacytoid dendritic cells in warts, hypogammaglobulinemia, infections, myelokathexis (WHIM) syndrome patients
Lenalidomide in combination with melphalan and dexamethasone in patients with newly diagnosed AL amyloidosis: a multicenter phase 1/2 dose-escalation study
Identification of novel cluster groups in pediatric high-risk B-precursor acute lymphoblastic leukemia with gene expression profiling: correlation with genome-wide DNA copy number alterations, clinical characteristics, and outcome
Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs
Photodepletion differentially affects CD4+ Tregs versus CD4+ effector T cells from patients with chronic graft-versus-host disease
Successful treatment of EBV-associated posttransplantation lymphoma after cord blood transplantation using third-party EBV-specific cytotoxic T lymphocytes
Issue Archive
December 2 2010
In this Issue
Table of Contents
Inside blood
Blood Work
Plenary Paper
PLENARY PAPER
Efficacy and safety of once-weekly bortezomib in multiple myeloma patients
Clinical Trials & Observations
Sara Bringhen,Alessandra Larocca,Davide Rossi,Maide Cavalli,Mariella Genuardi,Roberto Ria,Silvia Gentili,Francesca Patriarca,Chiara Nozzoli,Anna Levi,Tommasina Guglielmelli,Giulia Benevolo,Vincenzo Callea,Vincenzo Rizzo,Clotilde Cangialosi,Pellegrino Musto,Luca De Rosa,Anna Marina Liberati,Mariella Grasso,Antonietta P. Falcone,Andrea Evangelista,Michele Cavo,Gianluca Gaidano,Mario Boccadoro,Antonio Palumbo
Review Article
Perspectives
Clinical Trials and Observations
Immunoblastic morphology but not the immunohistochemical GCB/nonGCB classifier predicts outcome in diffuse large B-cell lymphoma in the RICOVER-60 trial of the DSHNHL
Clinical Trials & Observations
German Ott,Marita Ziepert,Wolfram Klapper,Heike Horn,Monika Szczepanowski,Heinz-Wolfram Bernd,Christoph Thorns,Alfred C. Feller,Dido Lenze,Michael Hummel,Harald Stein,Hans-Konrad Müller-Hermelink,Matthias Frank,Martin-Leo Hansmann,Thomas F. E. Barth,Peter Möller,Sergio Cogliatti,Michael Pfreundschuh,Norbert Schmitz,Lorenz Trümper,Markus Loeffler,Andreas Rosenwald
Hematopoiesis and Stem Cells
Immunobiology
Rapid generation of maturationally synchronized human dendritic cells: contribution to the clinical efficacy of extracorporeal photochemotherapy
Carole Berger,Kristin Hoffmann,Juan G. Vasquez,Shrikant Mane,Julia Lewis,Renata Filler,Aiping Lin,Hongyu Zhao,Tyler Durazzo,Abigail Baird,William Lin,Francine Foss,Inger Christensen,Michael Girardi,Robert Tigelaar,Richard Edelson
Anti-cytokine autoantibodies are associated with opportunistic infection in patients with thymic neoplasia
Peter D. Burbelo,Sarah K. Browne,Elizabeth P. Sampaio,Giuseppe Giaccone,Rifat Zaman,Ervand Kristosturyan,Arun Rajan,Li Ding,Kathryn H. Ching,Arlene Berman,Joao B. Oliveira,Amy P. Hsu,Caitlin M. Klimavicz,Michael J. Iadarola,Steven M. Holland
Defect of plasmacytoid dendritic cells in warts, hypogammaglobulinemia, infections, myelokathexis (WHIM) syndrome patients
Brief Report
Laura Tassone,Daniele Moratto,William Vermi,Maria De Francesco,Lucia D. Notarangelo,Fulvio Porta,Vassilios Lougaris,Fabio Facchetti,Alessandro Plebani,Raffaele Badolato
Lymphoid Neoplasia
Lenalidomide in combination with melphalan and dexamethasone in patients with newly diagnosed AL amyloidosis: a multicenter phase 1/2 dose-escalation study
Clinical Trials & Observations
Philippe Moreau,Arnaud Jaccard,Lotfi Benboubker,Bruno Royer,Xavier Leleu,Franck Bridoux,Gilles Salles,Veronique Leblond,Murielle Roussel,May Alakl,Olivier Hermine,Lucie Planche,Jean-Luc Harousseau,Jean-Paul Fermand
Identification of novel cluster groups in pediatric high-risk B-precursor acute lymphoblastic leukemia with gene expression profiling: correlation with genome-wide DNA copy number alterations, clinical characteristics, and outcome
Clinical Trials & Observations
Richard C. Harvey,Charles G. Mullighan,Xuefei Wang,Kevin K. Dobbin,George S. Davidson,Edward J. Bedrick,I-Ming Chen,Susan R. Atlas,Huining Kang,Kerem Ar,Carla S. Wilson,Walker Wharton,Maurice Murphy,Meenakshi Devidas,Andrew J. Carroll,Michael J. Borowitz,W. Paul Bowman,James R. Downing,Mary Relling,Jun Yang,Deepa Bhojwani,William L. Carroll,Bruce Camitta,Gregory H. Reaman,Malcolm Smith,Stephen P. Hunger,Cheryl L. Willman
Persistent expression of the full genome of hepatitis C virus in B cells induces spontaneous development of B-cell lymphomas in vivo
Yuri Kasama,Satoshi Sekiguchi,Makoto Saito,Kousuke Tanaka,Masaaki Satoh,Kazuhiko Kuwahara,Nobuo Sakaguchi,Motohiro Takeya,Yoichi Hiasa,Michinori Kohara,Kyoko Tsukiyama-Kohara
Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs
e-blood
Dereje D. Jima,Jenny Zhang,Cassandra Jacobs,Kristy L. Richards,Cherie H. Dunphy,William W. L. Choi,Wing Yan Au,Gopesh Srivastava,Magdalena B. Czader,David A. Rizzieri,Anand S. Lagoo,Patricia L. Lugar,Karen P. Mann,Christopher R. Flowers,Leon Bernal-Mizrachi,Kikkeri N. Naresh,Andrew M. Evens,Leo I. Gordon,Micah Luftig,Daphne R. Friedman,J. Brice Weinberg,Michael A. Thompson,Javed I. Gill,Qingquan Liu,Tam How,Vladimir Grubor,Yuan Gao,Amee Patel,Han Wu,Jun Zhu,Gerard C. Blobe,Peter E. Lipsky,Amy Chadburn,Sandeep S. Dave,for the Hematologic Malignancies Research Consortium (HMRC)
Myeloid Neoplasia
Phagocytes, Granulocytes, and Myelopoiesis
PtdIns3P and Rac direct the assembly of the NADPH oxidase on a novel, pre-phagosomal compartment during FcR-mediated phagocytosis in primary mouse neutrophils
Karen E. Anderson,Tamara A. M. Chessa,Keith Davidson,Robert B. Henderson,Simon Walker,Tanya Tolmachova,Katarzyna Grys,Oliver Rausch,Miguel C. Seabra,Victor L. J. Tybulewicz,Len R. Stephens,Phillip T. Hawkins
Platelets and Thrombopoiesis
Gray platelet syndrome: natural history of a large patient cohort and locus assignment to chromosome 3p
Meral Gunay-Aygun,Yifat Zivony-Elboum,Fatma Gumruk,Dan Geiger,Mualla Cetin,Morad Khayat,Robert Kleta,Nehama Kfir,Yair Anikster,Judith Chezar,Mauricio Arcos-Burgos,Adel Shalata,Horia Stanescu,Joseph Manaster,Mutlu Arat,Hailey Edwards,Andrew S. Freiberg,P. Suzanne Hart,Lauren C. Riney,Katherine Patzel,Pranoot Tanpaiboon,Tom Markello,Marjan Huizing,Irina Maric,McDonald Horne,Beate E. Kehrel,Kerstin Jurk,Nancy F. Hansen,Praveen F. Cherukuri,Marypat Jones,Pedro Cruz,Jim C. Mullikin,Alan Nurden,James G. White,William A. Gahl,Tzippora Falik-Zaccai
Red Cells, Iron, and Erythropoiesis
Thrombosis and Hemostasis
Transplantation
Photodepletion differentially affects CD4+ Tregs versus CD4+ effector T cells from patients with chronic graft-versus-host disease
Clinical Trials & Observations
Jean-Philippe Bastien,Gorazd Krosl,Cynthia Therien,Marissa Rashkovan,Christian Scotto,Sandra Cohen,David S. Allan,Donna Hogge,R. Maarten Egeler,Claude Perreault,Denis Claude Roy
Successful treatment of EBV-associated posttransplantation lymphoma after cord blood transplantation using third-party EBV-specific cytotoxic T lymphocytes
Brief Report
Juliet N. Barker,Ekaterina Doubrovina,Craig Sauter,Jennifer J. Jaroscak,Miguel A. Perales,Mikhail Doubrovin,Susan E. Prockop,Guenther Koehne,Richard J. O'Reilly
Vascular Biology
LPA4 regulates blood and lymphatic vessel formation during mouse embryogenesis
Hayakazu Sumida,Kyoko Noguchi,Yasuyuki Kihara,Manabu Abe,Keisuke Yanagida,Fumie Hamano,Shinichi Sato,Kunihiko Tamaki,Yasuyuki Morishita,Mitsunobu R. Kano,Caname Iwata,Kohei Miyazono,Kenji Sakimura,Takao Shimizu,Satoshi Ishii
Correspondence
Errata
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Cover Image
Cover Image
Plasma iron concentration and the availability of iron for erythropoiesis are controlled by the hepcidin-ferroportin interaction. Ferroportin (Fpn) is the iron exporter expressed on all cells supplying iron to plasma. The hepatic hormone hepcidin causes the degradation of ferroportin in these iron-exporting cells and thereby decreases the efflux of iron from cells into plasma. The article by Goodnough et al on page 4754 describes the role of the hepcidin-ferroportin axis in anemias.
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