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INSIDE BLOOD

IMMUNOBIOLOGY
CLINICAL TRIALS
INSIDE BLOOD
PHAGOCYTES & GRANULOCYTES
PLATELETS & THROMBOPOIESIS
THROMBOSIS & HEMOSTASIS

REVIEW ARTICLES

CLINICAL TRIALS AND OBSERVATIONS

GENE THERAPY

HEMATOPOIESIS AND STEM CELLS

IMMUNOBIOLOGY

LYMPHOID NEOPLASIA

MYELOID NEOPLASIA

PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS

PLATELETS AND THROMBOPOIESIS

RED CELLS, IRON, AND ERYTHROPOIESIS

THROMBOSIS AND HEMOSTASIS

TRANSPLANTATION

CORRESPONDENCE

  • Cover Image

    Cover Image

    issue cover

    Deconvolution of representative 2D XY focal plane was treated to allow Z scaling of pixel intensity (analyzed by Metamorph and ImageJ softwares). This representation was used to enhance the observation of TRAIL localization in the cytoplasm or its relocalization to the membrane. Unstimulated pDC (top image), HTLV-1–stimulated pDC (middle image) treated with chloroquine (bottom image) restrictively expressed TRAIL (green) in the cytoplasm in contrast to HTLV-1–activated pDC that expressed TRAIL at cell surface. Inhibitor of endosomal acidification, chloroquine, allowed detection of HTLV-1 particles (red) in the cytoplasm in contrast to the cell-surface detection of HTLV-1 virions in HTLV-1–activated pDC. See the article by Colisson et al on page 2177.

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