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INSIDE BLOOD

HEMATOPOIESIS & STEM CELLS
HEMATOPOIESIS & STEM CELLS
IMMUNOBIOLOGY
IMMUNOBIOLOGY
PLATELETS & THROMBOPOIESIS
THROMBOSIS & HEMOSTASIS

PLENARY PAPERS

REVIEW ARTICLES

CLINICAL TRIALS AND OBSERVATIONS

HEMATOPOIESIS AND STEM CELLS

IMMUNOBIOLOGY

LYMPHOID NEOPLASIA

MYELOID NEOPLASIA

PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS

PLATELETS AND THROMBOPOIESIS

RED CELLS, IRON, AND ERYTHROPOIESIS

THROMBOSIS AND HEMOSTASIS

TRANSPLANTATION

VASCULAR BIOLOGY

CORRESPONDENCE

  • Cover Image

    Cover Image

    issue cover

    MT1-MMP activity is required for endothelial lumen formation and generation of vascular guidance tunnels in 3-dimensional collagen matrices. GFP-labeled endothelial cells were seeded within 3-dimensional collagen matrices and allowed to form lumens and tube networks. Cultures were fixed at 96 hours and immunostained for the collagen type I matrix using a monoclonal antibody that recognizes native but not denatured collagen type I and an Alexa Fluor 594–conjugated secondary antibody. Fluorescent images were overlaid to reveal both the endothelial cell tube networks (green) and the vascular guidance tunnels (black areas) that are created during these events (the collagen matrix is stained red). See the article by Stratman et al on page 237.

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