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Lenalidomide, adriamycin, and dexamethasone (RAD) in patients with relapsed and refractory multiple myeloma: a report from the German Myeloma Study Group DSMM (Deutsche Studiengruppe Multiples Myelom)
Mature results of the M. D. Anderson Cancer Center risk-adapted transplantation strategy in mantle cell lymphoma
Improved risk classification for risk-specific therapy based on the molecular study of minimal residual disease (MRD) in adult acute lymphoblastic leukemia (ALL)
International prognostic scoring system for Waldenström macroglobulinemia
The role of cytogenetic abnormalities as a prognostic marker in primary myelofibrosis: applicability at the time of diagnosis and later during disease course
B-cell count and survival: differentiating chronic lymphocytic leukemia from monoclonal B-cell lymphocytosis based on clinical outcome
Issue Archive
Table of Contents
INSIDE BLOOD
CLINICAL TRIALS AND OBSERVATIONS
Lenalidomide, adriamycin, and dexamethasone (RAD) in patients with relapsed and refractory multiple myeloma: a report from the German Myeloma Study Group DSMM (Deutsche Studiengruppe Multiples Myelom)
Clinical Trials & Observations
Stefan Knop,Christian Gerecke,Peter Liebisch,Max S. Topp,Uwe Platzbecker,Orhan Sezer,Christina Vollmuth,Karina Falk,Axel Glasmacher,Uwe Maeder,Hermann Einsele,Ralf C. Bargou
Mature results of the M. D. Anderson Cancer Center risk-adapted transplantation strategy in mantle cell lymphoma
Clinical Trials & Observations
Constantine S. Tam,Roland Bassett,Celina Ledesma,Martin Korbling,Amin Alousi,Chitra Hosing,Partow Kebraei,Robyn Harrell,Gabriela Rondon,Sergio A. Giralt,Paolo Anderlini,Uday Popat,Barbara Pro,Barry Samuels,Frederick Hagemeister,L. Jeffrey Medeiros,Richard E. Champlin,Issa F. Khouri
Improved risk classification for risk-specific therapy based on the molecular study of minimal residual disease (MRD) in adult acute lymphoblastic leukemia (ALL)
Clinical Trials & Observations
Renato Bassan,Orietta Spinelli,Elena Oldani,Tamara Intermesoli,Manuela Tosi,Barbara Peruta,Giuseppe Rossi,Erika Borlenghi,Enrico M. Pogliani,Elisabetta Terruzzi,Pietro Fabris,Vincenzo Cassibba,Giorgio Lambertenghi-Deliliers,Agostino Cortelezzi,Alberto Bosi,Giacomo Gianfaldoni,Fabio Ciceri,Massimo Bernardi,Andrea Gallamini,Daniele Mattei,Eros Di Bona,Claudio Romani,Anna Maria Scattolin,Tiziano Barbui,Alessandro Rambaldi
International prognostic scoring system for Waldenström macroglobulinemia
Clinical Trials & Observations
Pierre Morel,Alain Duhamel,Paolo Gobbi,Meletios A. Dimopoulos,Madhav V. Dhodapkar,Jason McCoy,John Crowley,Enrique M. Ocio,Ramon Garcia-Sanz,Steven P. Treon,Veronique Leblond,Robert A. Kyle,Bart Barlogie,Giampaolo Merlini
The role of cytogenetic abnormalities as a prognostic marker in primary myelofibrosis: applicability at the time of diagnosis and later during disease course
Clinical Trials & Observations
Constantine S. Tam,Lynne V. Abruzzo,Katherine I. Lin,Jorge Cortes,Alice Lynn,Michael J. Keating,Deborah A. Thomas,Sherry Pierce,Hagop Kantarjian,Srdan Verstovsek
B-cell count and survival: differentiating chronic lymphocytic leukemia from monoclonal B-cell lymphocytosis based on clinical outcome
Clinical Trials & Observations
Tait D. Shanafelt,Neil E. Kay,Greg Jenkins,Timothy G. Call,Clive S. Zent,Diane F. Jelinek,William G. Morice,Justin Boysen,Liam Zakko,Susan Schwager,Susan L. Slager,Curtis A. Hanson
HEMATOPOIESIS AND STEM CELLS
IMMUNOBIOLOGY
Human plasmacytoid dendritic cells are unresponsive to bacterial stimulation and require a novel type of cooperation with myeloid dendritic cells for maturation
Diego Piccioli,Chiara Sammicheli,Simona Tavarini,Sandra Nuti,Elisabetta Frigimelica,Andrea G.O. Manetti,Annalisa Nuccitelli,Susanna Aprea,Sara Valentini,Erica Borgogni,Andreas Wack,Nicholas M. Valiante
LYMPHOID NEOPLASIA
CS1 promotes multiple myeloma cell adhesion, clonogenic growth, and tumorigenicity via c-maf–mediated interactions with bone marrow stromal cells
Yu-Tzu Tai,Ender Soydan,Weihua Song,Mariateresa Fulciniti,Kihyun Kim,Fangxin Hong,Xian-Feng Li,Peter Burger,Matthew J. Rumizen,Sabikun Nahar,Klaus Podar,Teru Hideshima,Nikhil C. Munshi,Giovanni Tonon,Ruben D. Carrasco,Daniel E. H. Afar,Kenneth C. Anderson
Inhibition of aurora kinases for tailored risk-adapted treatment of multiple myeloma
Dirk Hose,Thierry Rème,Tobias Meissner,Jérôme Moreaux,Anja Seckinger,Joe Lewis,Vladimir Benes,Axel Benner,Michael Hundemer,Thomas Hielscher,John D. Shaughnessy, Jr,Bart Barlogie,Kai Neben,Alwin Krämer,Jens Hillengass,Uta Bertsch,Anna Jauch,John De Vos,Jean-François Rossi,Thomas Möhler,Jonathon Blake,Jürgen Zimmermann,Bernard Klein,Hartmut Goldschmidt
CXCR4 inhibitor AMD3100 disrupts the interaction of multiple myeloma cells with the bone marrow microenvironment and enhances their sensitivity to therapy
Abdel Kareem Azab,Judith M. Runnels,Costas Pitsillides,Anne-Sophie Moreau,Feda Azab,Xavier Leleu,Xiaoying Jia,Renee Wright,Beatriz Ospina,Alicia L. Carlson,Clemens Alt,Nicholas Burwick,Aldo M. Roccaro,Hai T. Ngo,Mena Farag,Molly R. Melhem,Antonio Sacco,Nikhil C. Munshi,Teru Hideshima,Barrett J. Rollins,Kenneth C. Anderson,Andrew L. Kung,Charles P. Lin,Irene M. Ghobrial
Potent antitumor activity of the anti-CD19 auristatin antibody drug conjugate hBU12-vcMMAE against rituximab-sensitive and -resistant lymphomas
Hans-Peter Gerber,May Kung-Sutherland,Ivan Stone,Carol Morris-Tilden,Jamie Miyamoto,Renee McCormick,Stephen C. Alley,Nicole Okeley,Brad Hayes,Francisco J. Hernandez-Ilizaliturri,Charlotte F. McDonagh,Paul J. Carter,Dennis Benjamin,Iqbal S. Grewal
microRNA expression in the biology, prognosis, and therapy of Waldenström macroglobulinemia
Aldo M. Roccaro,Antonio Sacco,Changzhong Chen,Judith Runnels,Xavier Leleu,Feda Azab,Abdel Kareem Azab,Xiaoying Jia,Hai T. Ngo,Molly R. Melhem,Nicholas Burwick,Lyuba Varticovski,Carl D. Novina,Barrett J. Rollins,Kenneth C. Anderson,Irene M. Ghobrial
MYELOID NEOPLASIA
THROMBOSIS AND HEMOSTASIS
TRANSPLANTATION
Donor T cells primed on leukemia lysate-pulsed recipient APCs mediate strong graft-versus-leukemia effects across MHC barriers in full chimeras
Arnab Ghosh,Wolfgang Koestner,Martin Hapke,Verena Schlaphoff,Florian Länger,Rolf Baumann,Christian Koenecke,Markus Cornberg,Karl Welte,Bruce R. Blazar,Martin G. Sauer
VASCULAR BIOLOGY
Vascular endothelial growth factor-D transgenic mice show enhanced blood capillary density, improved postischemic muscle regeneration, and increased susceptibility to tumor formation
Anna-Mari Kärkkäinen,Antti Kotimaa,Jenni Huusko,Ivana Kholova,Suvi Elina Heinonen,Anna Stefanska,Marike Hinke Dijkstra,Hanna Purhonen,Eveliina Hämäläinen,Petri Ilmari Mäkinen,Mikko Petri Turunen,Seppo Ylä-Herttuala
CORRESPONDENCE
ERRATUM
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Cover Image
Cover Image
The crystal structure of BβD432A fibrinogen fragment D in complex with knob "B" peptide mimic revealed surprising findings on the importance of hole "b" and "B:b" interactions in fibrin polymerization. For details see the article by Bowley and Lord on page 4425.
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