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Residual vein thrombosis to establish duration of anticoagulation after a first episode of deep vein thrombosis: the Duration of Anticoagulation based on Compression UltraSonography (DACUS) study
Failure to achieve a major cytogenetic response by 12 months defines inadequate response in patients receiving nilotinib or dasatinib as second or subsequent line therapy for chronic myeloid leukemia
Restrictive usage of monoclonal immunoglobulin λ light chain germline in POEMS syndrome
Characteristics and clinical correlates of MPL 515W>L/K mutation in essential thrombocythemia
Issue Archive
August 1 2008
In this Issue
Table of Contents
INSIDE BLOOD
ASH 50TH ANNIVERSARY REVIEW
BLOOD WORK
PLENARY PAPERS
CHEMOKINES, CYTOKINES, AND INTERLEUKINS
CLINICAL TRIALS AND OBSERVATIONS
Residual vein thrombosis to establish duration of anticoagulation after a first episode of deep vein thrombosis: the Duration of Anticoagulation based on Compression UltraSonography (DACUS) study
Clinical Trials & Observations
Sergio Siragusa,Alessandra Malato,Raffaela Anastasio,Valeria Cigna,Glauco Milio,Corrado Amato,Mario Bellisi,Maria Teresa Attanzio,Oreste Cormaci,Massimo Pellegrino,Alberto Dolce,Alessandra Casuccio,Guido Bajardi,Guglielmo Mariani
Failure to achieve a major cytogenetic response by 12 months defines inadequate response in patients receiving nilotinib or dasatinib as second or subsequent line therapy for chronic myeloid leukemia
Brief Report
Constantine S. Tam,Hagop Kantarjian,Guillermo Garcia-Manero,Gautam Borthakur,Susan O'Brien,Farhad Ravandi,Jenny Shan,Jorge Cortes
HEMATOPOIESIS AND STEM CELLS
Anti-CD38 antibody–mediated clearance of human repopulating cells masks the heterogeneity of leukemia-initiating cells
David C. Taussig,Farideh Miraki-Moud,Fernando Anjos-Afonso,Daniel J. Pearce,Kirsty Allen,Christopher Ridler,Debra Lillington,Heather Oakervee,Jamie Cavenagh,Samir G. Agrawal,T. Andrew Lister,John G. Gribben,Dominique Bonnet
HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY
RGT, a synthetic peptide corresponding to the integrin β3 cytoplasmic C-terminal sequence, selectively inhibits outside-in signaling in human platelets by disrupting the interaction of integrin αIIbβ3 with Src kinase
Xiaoyu Su,Jianqing Mi,Jinsong Yan,Panagiotis Flevaris,Yuanjing Lu,Hongchen Liu,Zheng Ruan,Xuefeng Wang,Nelly Kieffer,Saijuan Chen,Xiaoping Du,Xiaodong Xi
IMMUNOBIOLOGY
Fc-dependent expression of CD137 on human NK cells: insights into “agonistic” effects of anti-CD137 monoclonal antibodies
Wei Lin,Caroline J. Voskens,Xiaoyu Zhang,Daniel G. Schindler,Aaron Wood,Erin Burch,Yadong Wei,Lieping Chen,Guoliang Tian,Koji Tamada,Lai-Xi Wang,Dan H. Schulze,Dean Mann,Scott E. Strome
NEOPLASIA
The antileukemia activity of a human anti-CD40 antagonist antibody, HCD122, on human chronic lymphocytic leukemia cells
Mohammad Luqman,Sha Klabunde,Karen Lin,Georgios V. Georgakis,Anu Cherukuri,Jocelyn Holash,Cheryl Goldbeck,Xiaomei Xu,Edward E. Kadel, III,Sang Hoon Lee,Sharon Lea Aukerman,Bahija Jallal,Natasha Aziz,Wen-Kai Weng,William Wierda,Susan O'Brien,Anas Younes
Constitutive expression of IL-12Rβ2 on human multiple myeloma cells delineates a novel therapeutic target
Irma Airoldi,Claudia Cocco,Nicola Giuliani,Marina Ferrarini,Simona Colla,Emanuela Ognio,Giuseppe Taverniti,Emma Di Carlo,Giovanna Cutrona,Vittorio Perfetti,Vittorio Rizzoli,Domenico Ribatti,Vito Pistoia
Cyproheptadine displays preclinical activity in myeloma and leukemia
Xinliang Mao,Sheng-ben Liang,Rose Hurren,Marcela Gronda,Sue Chow,G. Wei Xu,Xiaoming Wang,Reza Beheshti Zavareh,Nazir Jamal,Hans Messner,David W. Hedley,Alessandro Datti,Jeff L. Wrana,Yuanxiao Zhu,Chang-xin Shi,Kyle Lee,Rodger Tiedemann,Suzanne Trudel,A. Keith Stewart,Aaron D. Schimmer
BCR ligation induced by IgM stimulation results in gene expression and functional changes only in IgVH unmutated chronic lymphocytic leukemia (CLL) cells
Anna Guarini,Sabina Chiaretti,Simona Tavolaro,Roberta Maggio,Nadia Peragine,Franca Citarella,Maria Rosaria Ricciardi,Simona Santangelo,Marilisa Marinelli,Maria Stefania De Propris,Monica Messina,Francesca Romana Mauro,Ilaria Del Giudice,Robert Foà
Restrictive usage of monoclonal immunoglobulin λ light chain germline in POEMS syndrome
Brief Report
Daijiro Abe,Chiaki Nakaseko,Masahiro Takeuchi,Hiroaki Tanaka,Chikako Ohwada,Emiko Sakaida,Yusuke Takeda,Kayo Oda,Shinichi Ozawa,Naomi Shimizu,Shinichi Masuda,Ryuko Cho,Miki Nishimura,Sonoko Misawa,Satoshi Kuwabara,Yasushi Saito
Characteristics and clinical correlates of MPL 515W>L/K mutation in essential thrombocythemia
Brief Report
Alessandro M. Vannucchi,Elisabetta Antonioli,Paola Guglielmelli,Alessandro Pancrazzi,Vittoria Guerini,Giovanni Barosi,Marco Ruggeri,Giorgina Specchia,Francesco Lo-Coco,Federica Delaini,Laura Villani,Silvia Finotto,Emanuele Ammatuna,Renato Alterini,Valentina Carrai,Gloria Capaccioli,Simonetta Di Lollo,Vincenzo Liso,Alessandro Rambaldi,Alberto Bosi,Tiziano Barbui
PHAGOCYTES
RED CELLS
Decreased differentiation of erythroid cells exacerbates ineffective erythropoiesis in β-thalassemia
Ilaria V. Libani,Ella C. Guy,Luca Melchiori,Raffaella Schiro,Pedro Ramos,Laura Breda,Thomas Scholzen,Amy Chadburn,YiFang Liu,Margrit Kernbach,Bettina Baron-Lühr,Matteo Porotto,Maria de Sousa,Eliezer A. Rachmilewitz,John D. Hood,M. Domenica Cappellini,Patricia J. Giardina,Robert W. Grady,Johannes Gerdes,Stefano Rivella
TRANSFUSION MEDICINE
TRANSPLANTATION
WHO classification and WPSS predict posttransplantation outcome in patients with myelodysplastic syndrome: a study from the Gruppo Italiano Trapianto di Midollo Osseo (GITMO)
Emilio Paolo Alessandrino,Matteo Giovanni Della Porta,Andrea Bacigalupo,Maria Teresa Van Lint,Michele Falda,Francesco Onida,Massimo Bernardi,Anna Paola Iori,Alessandro Rambaldi,Raffaella Cerretti,Paola Marenco,Pietro Pioltelli,Luca Malcovati,Cristiana Pascutto,Rosi Oneto,Renato Fanin,Alberto Bosi
Long-term remission of Philadelphia chromosome–positive acute lymphoblastic leukemia after allogeneic hematopoietic cell transplantation from matched sibling donors: a 20-year experience with the fractionated total body irradiation–etoposide regimen
Ginna G. Laport,Joseph C. Alvarnas,Joycelynne M. Palmer,David S. Snyder,Marilyn L. Slovak,Athena M. Cherry,Ruby M. Wong,Robert S. Negrin,Karl G. Blume,Stephen J. Forman
CORRESPONDENCE
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Cover Image
Cover Image
Confocal immunofluorescence image of an erythroblastic island reconstituted from freshly harvested mouse bone marrow cells showing a multilobulated reticulocyte stained in red with an erythroid-specific marker, a central macrophage stained in green, and nuclei stained blue with a DNA probe. Reproduced from Lee et al. Blood. 2006;108:2064-2071. See the related article in this issue by Chasis and Mohandas, beginning on page 470.
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