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Dendritic cell and natural killer cell cross-talk: a pivotal role of CX3CL1 in NK cytoskeleton organization and activation
Sirolimus is associated with veno-occlusive disease of the liver after myeloablative allogeneic stem cell transplantation
Influence of thrombophilia on risk of recurrent venous thromboembolism while on warfarin: results from a randomized trial
European LeukemiaNet criteria for failure or suboptimal response reliably identify patients with CML in early chronic phase treated with imatinib whose eventual outcome is poor
Lenalidomide plus dexamethasone is more effective than dexamethasone alone in patients with relapsed or refractory multiple myeloma regardless of prior thalidomide exposure
Thalidomide and rituximab in Waldenstrom macroglobulinemia
Factor H, membrane cofactor protein, and factor I mutations in patients with hemolysis, elevated liver enzymes, and low platelet count syndrome
Clinical improvement by farnesyltransferase inhibition in NK large granular lymphocyte leukemia associated with imbalanced NK receptor signaling
Issue Archive
December 1 2008
In this Issue
Table of Contents
INSIDE BLOOD
ASH 50TH ANNIVERSARY REVIEWS
BLOOD WORK
CHEMOKINES, CYTOKINES, AND INTERLEUKINS
Dendritic cell and natural killer cell cross-talk: a pivotal role of CX3CL1 in NK cytoskeleton organization and activation
Brief Report
Jean R. Pallandre,Konrad Krzewski,Romain Bedel,Bernhard Ryffel,Anne Caignard,Pierre Simon Rohrlich,Xavier Pivot,Pierre Tiberghien,Laurence Zitvogel,Jack L. Strominger,Christophe Borg
CLINICAL TRIALS AND OBSERVATIONS
Sirolimus is associated with veno-occlusive disease of the liver after myeloablative allogeneic stem cell transplantation
Clinical Trials & Observations
Corey Cutler,Kristen Stevenson,Haesook T. Kim,Paul Richardson,Vincent T. Ho,Erica Linden,Carolyn Revta,Ruth Ebert,Diane Warren,Sung Choi,John Koreth,Philippe Armand,Edwin Alyea,Shelly Carter,Mary Horowitz,Joseph H. Antin,Robert Soiffer
Influence of thrombophilia on risk of recurrent venous thromboembolism while on warfarin: results from a randomized trial
Clinical Trials & Observations
Clive Kearon,for the ELATE Investigators,Jim A. Julian,for the ELATE Investigators,Michael J. Kovacs,for the ELATE Investigators,David R. Anderson,for the ELATE Investigators,Philip Wells,for the ELATE Investigators,Betsy MacKinnon,for the ELATE Investigators,Jeffrey I. Weitz,for the ELATE Investigators,Mark A. Crowther,for the ELATE Investigators,Sean Dolan,for the ELATE Investigators,Alexander G. Turpie,for the ELATE Investigators,William Geerts,for the ELATE Investigators,Susan Solymoss,for the ELATE Investigators,Paul van Nguyen,for the ELATE Investigators,Christine Demers,for the ELATE Investigators,Susan R. Kahn,for the ELATE Investigators,Jeannine Kassis,for the ELATE Investigators,Marc Rodger,for the ELATE Investigators,Julie Hambleton,for the ELATE Investigators,Michael Gent,for the ELATE Investigators,Jeffrey S. Ginsberg,for the ELATE Investigators
European LeukemiaNet criteria for failure or suboptimal response reliably identify patients with CML in early chronic phase treated with imatinib whose eventual outcome is poor
Clinical Trials & Observations
David Marin,Dragana Milojkovic,Eduardo Olavarria,Jamshid S. Khorashad,Hugues de Lavallade,Alistair G. Reid,Letizia Foroni,Katayoun Rezvani,Marco Bua,Francesco Dazzi,Jiri Pavlu,Matthias Klammer,Jaspal S. Kaeda,John M. Goldman,Jane F. Apperley
Lenalidomide plus dexamethasone is more effective than dexamethasone alone in patients with relapsed or refractory multiple myeloma regardless of prior thalidomide exposure
Clinical Trials & Observations
Michael Wang,Meletios A. Dimopoulos,Christine Chen,M. Teresa Cibeira,Michel Attal,Andrew Spencer,S. Vincent Rajkumar,Zhinuan Yu,Marta Olesnyckyj,Jerome B. Zeldis,Robert D. Knight,Donna M. Weber
Thalidomide and rituximab in Waldenstrom macroglobulinemia
Clinical Trials & Observations
Steven P. Treon,Jacob D. Soumerai,Andrew R. Branagan,Zachary R. Hunter,Christopher J. Patterson,Leukothea Ioakimidis,Frederick M. Briccetti,Mark Pasmantier,Harvey Zimbler,Robert B. Cooper,Maria Moore,John Hill, II,Alan Rauch,Lawrence Garbo,Luis Chu,Cynthia Chua,Stephen H. Nantel,David R. Lovett,Hans Boedeker,Henry Sonneborn,John Howard,Paul Musto,Bryan T. Ciccarelli,Evdoxia Hatjiharissi,Kenneth C. Anderson
GENE THERAPY
HEMATOPOIESIS AND STEM CELLS
HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY
Endoglin expression in blood and endothelium is differentially regulated by modular assembly of the Ets/Gata hemangioblast code
John E. Pimanda,Wan Y. I. Chan,Nicola K. Wilson,Aileen M. Smith,Sarah Kinston,Kathy Knezevic,Mary E. Janes,Josette-Renée Landry,Anja Kolb-Kokocinski,Jonathan Frampton,David Tannahill,Katrin Ottersbach,George A. Follows,Georges Lacaud,Valerie Kouskoff,Berthold Göttgens
Factor H, membrane cofactor protein, and factor I mutations in patients with hemolysis, elevated liver enzymes, and low platelet count syndrome
Brief Report
Fadi Fakhouri,Mathieu Jablonski,Jacques Lepercq,Jacques Blouin,Alexandra Benachi,Maryvonne Hourmant,Yves Pirson,Antoine Dürrbach,Jean-Pierre Grünfeld,Bertrand Knebelmann,Véronique Frémeaux-Bacchi
IMMUNOBIOLOGY
Primary infection with simian immunodeficiency virus: plasmacytoid dendritic cell homing to lymph nodes, type I interferon, and immune suppression
Benoît Malleret,Benjamin Manéglier,Ingrid Karlsson,Pierre Lebon,Michelina Nascimbeni,Leïla Perié,Patricia Brochard,Benoît Delache,Julien Calvo,Thibault Andrieu,Odile Spreux-Varoquaux,Anne Hosmalin,Roger Le Grand,Bruno Vaslin
Expanded cells in monoclonal TCR-αβ+/CD4+/NKa+/CD8−/+dim T-LGL lymphocytosis recognize hCMV antigens
Arancha Rodríguez-Caballero,Andrés C. García-Montero,Paloma Bárcena,Julia Almeida,Francisco Ruiz-Cabello,Maria Dolores Tabernero,Pilar Garrido,Santiago Muñoz-Criado,Yorick Sandberg,Anton W. Langerak,Marcos González,Ana Balanzategui,Alberto Orfao
NEOPLASIA
Five new pedigrees with inherited RUNX1 mutations causing familial platelet disorder with propensity to myeloid malignancy
Carolyn J. Owen,Cynthia L. Toze,Anna Koochin,Donna L. Forrest,Clayton A. Smith,Jane M. Stevens,Shannon C. Jackson,Man-Chiu Poon,Gary D. Sinclair,Brian Leber,Peter R. E. Johnson,Anthony Macheta,John A. L. Yin,Michael J. Barnett,T. Andrew Lister,Jude Fitzgibbon
Leukemic challenge unmasks a requirement for PI3Kδ in NK cell–mediated tumor surveillance
Eva Zebedin,Olivia Simma,Christian Schuster,Eva Maria Putz,Sabine Fajmann,Wolfgang Warsch,Eva Eckelhart,Dagmar Stoiber,Eva Weisz,Johannes A. Schmid,Winfried F. Pickl,Christian Baumgartner,Peter Valent,Roland P. Piekorz,Michael Freissmuth,Veronika Sexl
Geldanamycin-induced Lyn dissociation from aberrant Hsp90-stabilized cytosolic complex is an early event in apoptotic mechanisms in B-chronic lymphocytic leukemia
Livio Trentin,Martina Frasson,Arianna Donella-Deana,Federica Frezzato,Mario A. Pagano,Elena Tibaldi,Cristina Gattazzo,Renato Zambello,Gianpietro Semenzato,Anna M. Brunati
CD27-CD70 interactions in the pathogenesis of Waldenström macroglobulinemia
Allen W. Ho,Evdoxia Hatjiharissi,Bryan T. Ciccarelli,Andrew R. Branagan,Zachary R. Hunter,Xavier Leleu,Olivier Tournilhac,Lian Xu,Kelly O'Connor,Robert J. Manning,Daniel Ditzel Santos,Mariana Chemaly,Christopher J. Patterson,Jacob D. Soumerai,Nikhil C. Munshi,Julie A. McEarchern,Che-Leung Law,Iqbal S. Grewal,Steven P. Treon
Clinical improvement by farnesyltransferase inhibition in NK large granular lymphocyte leukemia associated with imbalanced NK receptor signaling
Brief Report
P. K. Epling-Burnette,Lubomir Sokol,Xianhong Chen,Fanqi Bai,Junmin Zhou,Michelle A. Blaskovich,JianXiang Zou,Jeffrey S. Painter,Todd D. Edwards,Lynn Moscinski,Jeffrey A. Yoder,Julie Y. Djeu,Said Sebti,Thomas P. Loughran, Jr,Sheng Wei
PHAGOCYTES
RED CELLS
TRANSFUSION MEDICINE
TRANSPLANTATION
Adoptive transfer of allogeneic tumor-specific T cells mediates effective regression of large tumors across major histocompatibility barriers
Andrea Boni,Pawel Muranski,Lydie Cassard,Claudia Wrzesinski,Chrystal M. Paulos,Douglas C. Palmer,Luca Gattinoni,Christian S. Hinrichs,Chi-Chao Chan,Steven A. Rosenberg,Nicholas P. Restifo
Rapidly proliferating CD44hi peripheral T cells undergo apoptosis and delay posttransplantation T-cell reconstitution after allogeneic bone marrow transplantation
S. Önder Alpdogan,Sydney X. Lu,Neel Patel,Suzanne McGoldrick,David Suh,Tulin Budak-Alpdogan,Odette M. Smith,Jeremy Grubin,Christopher King,Gabrielle L. Goldberg,Vanessa M. Hubbard,Adam A. Kochman,Marcel R. M. van den Brink
CORRESPONDENCE
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Cover Image
Cover Image
![issue cover]()
Representative example of a BFU-E colony grown from trisomy 21 fetal liver cells. T21 BFU-E colonies tended to be larger, with the majority approximately twice the size of control colonies. Original magnification ×10. See the article by Chou et al on page 4503.
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