Skip Nav Destination

Issue Archive

Select Decade

Select Year

Issue

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

Relative antithrombotic and antihemostatic effects of protein C activator versus low-molecular-weight heparin in primates

András Gruber,Ulla M. Marzec,Leslie Bush,Enrico Di Cera,José A. Fernández,Michelle A. Berny,Erik I. Tucker,Owen J. T. McCarty,John H. Griffin,Stephen R. Hanson

View Articletitled, Relative antithrombotic and antihemostatic effects of protein C activator versus low-molecular-weight heparin in primates

A sequence variation scan of the coagulation factor VIII (FVIII) structural gene and associations with plasma FVIII activity levels

Kevin R. Viel,Deepa K. Machiah,Diane M. Warren,Manana Khachidze,Alfonso Buil,Karl Fernstrom,Juan C. Souto,Juan M. Peralta,Todd Smith,John Blangero,Sandra Porter,Stephen T. Warren,Jordi Fontcuberta,Jose M. Soria,W. Dana Flanders,Laura Almasy,Tom E. Howard

View Articletitled, A sequence variation scan of the coagulation factor VIII (FVIII) structural gene and associations with plasma FVIII activity levels

Supplemental data

Mapping early conformational changes in αIIb and β3 during biogenesis reveals a potential mechanism for αIIbβ3 adopting its bent conformation

W. Beau Mitchell,Jihong Li,Marta Murcia,Nathalie Valentin,Peter J. Newman,Barry S. Coller

View Articletitled, Mapping early conformational changes in αIIb and β3 during biogenesis reveals a potential mechanism for αIIbβ3 adopting its bent conformation

Supplemental data

Nongenomic signaling of the retinoid X receptor through binding and inhibiting Gq in human platelets

Leonardo A. Moraes,Karen E. Swales,Jessica A. Wray,Amilcar Damazo,Jonathan M. Gibbins,Timothy D. Warner,David Bishop-Bailey

View Articletitled, Nongenomic signaling of the retinoid X receptor through binding and inhibiting Gq in human platelets

Supplemental data

Endorepellin, the C-terminal angiostatic module of perlecan, enhances collagen-platelet responses via the α2β1-integrin receptor
Brief Report

Gregory Bix,Rex A. Iozzo,Ben Woodall,Michelle Burrows,Angela McQuillan,Shelly Campbell,Gregg B. Fields,Renato V. Iozzo

View Articletitled, Endorepellin, the C-terminal angiostatic module of perlecan, enhances collagen-platelet responses via the α2β1-integrin receptor

Supplemental data

INSIDE BLOOD

IMMUNOBIOLOGY

KGF boosts thymic archiTECture

Yu-Waye Chu,Frances T. Hakim

View Articletitled, KGF boosts thymic archiTECture

IMMUNOBIOLOGY

Control LPS or get killed

Noam Stern-Ginossar,Ofer Mandelboim

View Articletitled, Control LPS or get killed

IMMUNOBIOLOGY

FcγRs join in the cascade

Francis W. Luscinskas,Tanya Mayadas

View Articletitled, FcγRs join in the cascade

IMMUNOBIOLOGY

Understand tolerogenic dendritic cells

Katharina E. Tschoep,Elfriede Noessner

View Articletitled, Understand tolerogenic dendritic cells

TRANSPLANTATION

ProTECtion from posttransplantation immune deficiency?

Kenneth I. Weinberg

View Articletitled, ProTECtion from posttransplantation immune deficiency?

IMMUNOBIOLOGY

Glis: novel modulators of TCR signaling?

Ursula Bommhardt

View Articletitled, Glis: novel modulators of TCR signaling?

NEOPLASIA

Survival signaling in HoxA9/Meis1 AML

Gang G. Wang,Mark P. Kamps

View Articletitled, Survival signaling in HoxA9/Meis1 AML

PHAGOCYTES

Braking neutrophils with PTEN

Lee-Ann H. Allen

View Articletitled, Braking neutrophils with PTEN

NEOPLASIA

Gene expression levels in lymphoma

Philip S. Rosenberg

View Articletitled, Gene expression levels in lymphoma

IMMUNOBIOLOGY

Bcl-B and Nur77/TR3: a deadly combination

Dharminder Chauhan,Kenneth C. Anderson

View Articletitled, Bcl-B and Nur77/TR3: a deadly combination

BLOOD WORK

Chronic lymphocytic leukemia: bone marrow aspirate

View Articletitled, Chronic lymphocytic leukemia: bone marrow aspirate

CHEMOKINES, CYTOKINES, AND INTERLEUKINS

The role of chemerin in the colocalization of NK and dendritic cell subsets into inflamed tissues

Silvia Parolini,Amerigo Santoro,Emanuela Marcenaro,Walter Luini,Luisa Massardi,Fabio Facchetti,David Communi,Marc Parmentier,Alessandra Majorana,Marina Sironi,Giovanna Tabellini,Alessandro Moretta,Silvano Sozzani

View Articletitled, The role of chemerin in the colocalization of NK and dendritic cell subsets into inflamed tissues

Supplemental data

Inhibition of HIV-1 infection by viral chemokine U83A via high-affinity CCR5 interactions that block human chemokine-induced leukocyte chemotaxis and receptor internalization

Julie Catusse,Chris M. Parry,David R. Dewin,Ursula A. Gompels

View Articletitled, Inhibition of HIV-1 infection by viral chemokine U83A via high-affinity CCR5 interactions that block human chemokine-induced leukocyte chemotaxis and receptor internalization

Mast cell–derived TNF can promote Th17 cell–dependent neutrophil recruitment in ovalbumin-challenged OTII mice

Susumu Nakae,Hajime Suto,Gerald J. Berry,Stephen J. Galli

View Articletitled, Mast cell–derived TNF can promote Th17 cell–dependent neutrophil recruitment in ovalbumin-challenged OTII mice

Supplemental data

Trapping and apoptosis of novel subsets of memory T lymphocytes expressing CCR6 in the spleen of HIV-infected patients

Cédric Lécureuil,Béhazine Combadière,Elodie Mazoyer,Olivia Bonduelle,Assia Samri,Brigitte Autran,Patrice Debré,Christophe Combadière

View Articletitled, Trapping and apoptosis of novel subsets of memory T lymphocytes expressing CCR6 in the spleen of HIV-infected patients

Supplemental data

ERRATUM

Erratum for Nishimura et al., Thrombin-activatable procarboxypeptidase B regulates activated complement C5a in vivo

View Articletitled, Erratum for Nishimura et al., Thrombin-activatable procarboxypeptidase B regulates activated complement C5a in vivo

CLINICAL TRIALS AND OBSERVATIONS

Results of a HOVON/SAKK donor versus no-donor analysis of myeloablative HLA-identical sibling stem cell transplantation in first remission acute myeloid leukemia in young and middle-aged adults: benefits for whom?
Clinical Trials & Observations

Jan J. Cornelissen,Wim L. J. van Putten,Leo F. Verdonck,Matthias Theobald,Emanuel Jacky,Simon M. G. Daenen,Marinus van Marwijk Kooy,Pierre Wijermans,Harry Schouten,Peter C. Huijgens,Hans van der Lelie,Martin Fey,Augustin Ferrant,Johan Maertens,Alois Gratwohl,Bob Lowenberg

View Articletitled, Results of a HOVON/SAKK donor versus no-donor analysis of myeloablative HLA-identical sibling stem cell transplantation in first remission acute myeloid leukemia in young and middle-aged adults: benefits for whom?

Supplemental data

Progression to end-stage liver disease in patients with inherited bleeding disorders and hepatitis C: an international, multicenter cohort study
Clinical Trials & Observations

Dirk Posthouwer,Michael Makris,Thynn T. Yee,Kathelijn Fischer,Joost J. van Veen,Anja Griffioen,Karel J. van Erpecum,Eveline P. Mauser-Bunschoten

View Articletitled, Progression to end-stage liver disease in patients with inherited bleeding disorders and hepatitis C: an international, multicenter cohort study

Cladribine in a weekly versus daily schedule for untreated active hairy cell leukemia: final report from the Polish Adult Leukemia Group (PALG) of a prospective, randomized, multicenter trial
Clinical Trials & Observations Brief Report

View Articletitled, Cladribine in a weekly versus daily schedule for untreated active hairy cell leukemia: final report from the Polish Adult Leukemia Group (PALG) of a prospective, randomized, multicenter trial

Imatinib plus steroids induces complete remissions and prolonged survival in elderly Philadelphia chromosome–positive patients with acute lymphoblastic leukemia without additional chemotherapy: results of the Gruppo Italiano Malattie Ematologiche dell'Adulto (GIMEMA) LAL0201-B protocol
Clinical Trials & Observations Brief Report

Marco Vignetti,Paola Fazi,Giuseppe Cimino,Giovanni Martinelli,Francesco Di Raimondo,Felicetto Ferrara,Giovanna Meloni,Achille Ambrosetti,Giovanni Quarta,Livio Pagano,Giovanna Rege-Cambrin,Loredana Elia,Raffaello Bertieri,Luciana Annino,Robin Foà,Michele Baccarani,Franco Mandelli

View Articletitled, Imatinib plus steroids induces complete remissions and prolonged survival in elderly Philadelphia chromosome–positive patients with acute lymphoblastic leukemia without additional chemotherapy: results of the Gruppo Italiano Malattie Ematologiche dell'Adulto (GIMEMA) LAL0201-B protocol

Supplemental data

HEMATOPOIESIS

Involvement of Fyn kinase in Kit and integrin-mediated Rac activation, cytoskeletal reorganization, and chemotaxis of mast cells

Lionel A. Samayawardhena,Reuben Kapur,Andrew W. B. Craig

View Articletitled, Involvement of Fyn kinase in Kit and integrin-mediated Rac activation, cytoskeletal reorganization, and chemotaxis of mast cells

HOXA10 is a critical regulator for hematopoietic stem cells and erythroid/megakaryocyte development

Mattias Magnusson,Ann C. M. Brun,Noriko Miyake,Jonas Larsson,Mats Ehinger,Jon Mar Bjornsson,Anton Wutz,Mikael Sigvardsson,Stefan Karlsson

View Articletitled, HOXA10 is a critical regulator for hematopoietic stem cells and erythroid/megakaryocyte development

Supplemental data

Ectopic expression of PAX5 promotes maintenance of biphenotypic myeloid progenitors coexpressing myeloid and B-cell lineage-associated genes

Kristina Anderson,Corinne Rusterholz,Robert Månsson,Christina T. Jensen,Karl Bacos,Sasan Zandi,Yutaka Sasaki,Claus Nerlov,Mikael Sigvardsson,Sten Eirik W. Jacobsen

View Articletitled, Ectopic expression of PAX5 promotes maintenance of biphenotypic myeloid progenitors coexpressing myeloid and B-cell lineage-associated genes

Supplemental data

Osteoblasts support B-lymphocyte commitment and differentiation from hematopoietic stem cells

Jiang Zhu,Russell Garrett,Younghun Jung,Yi Zhang,Nacksung Kim,Jingcheng Wang,Gerard J. Joe,Elizabeth Hexner,Yongwon Choi,Russell S. Taichman,Stephen G. Emerson

View Articletitled, Osteoblasts support B-lymphocyte commitment and differentiation from hematopoietic stem cells

Supplemental data

IMMUNOBIOLOGY

Sphingosine 1-phosphate regulates peritoneal B-cell trafficking for subsequent intestinal IgA production

Jun Kunisawa,Yosuke Kurashima,Masashi Gohda,Morio Higuchi,Izumi Ishikawa,Fumi Miura,Ikuko Ogahara,Hiroshi Kiyono

View Articletitled, Sphingosine 1-phosphate regulates peritoneal B-cell trafficking for subsequent intestinal IgA production

Activation of the Hedgehog signaling pathway in T-lineage cells inhibits TCR repertoire selection in the thymus and peripheral T-cell activation

Nicola J. Rowbotham,Ariadne L. Hager-Theodorides,Marek Cebecauer,Divya K. Shah,Ekati Drakopoulou,Julian Dyson,Susan V. Outram,Tessa Crompton

View Articletitled, Activation of the Hedgehog signaling pathway in T-lineage cells inhibits TCR repertoire selection in the thymus and peripheral T-cell activation

Molecular analysis of the methylprednisolone-mediated inhibition of NK-cell function: evidence for different susceptibility of IL-2– versus IL-15–activated NK cells

Laura Chiossone,Chiara Vitale,Francesca Cottalasso,Sara Moretti,Bruno Azzarone,Lorenzo Moretta,Maria Cristina Mingari

View Articletitled, Molecular analysis of the methylprednisolone-mediated inhibition of NK-cell function: evidence for different susceptibility of IL-2– versus IL-15–activated NK cells

Supplemental data

Reciprocal regulation of human natural killer cells and macrophages associated with distinct immune synapses

Shlomo Nedvetzki,Stefanie Sowinski,Robert A. Eagle,James Harris,Frédéric Vély,Daniela Pende,John Trowsdale,Eric Vivier,Siamon Gordon,Daniel M. Davis

View Articletitled, Reciprocal regulation of human natural killer cells and macrophages associated with distinct immune synapses

Supplemental data

FcRL6, a new ITIM-bearing receptor on cytolytic cells, is broadly expressed by lymphocytes following HIV-1 infection

Timothy J. Wilson,Rachel M. Presti,Ilaria Tassi,Edgar T. Overton,Marina Cella,Marco Colonna

View Articletitled, FcRL6, a new ITIM-bearing receptor on cytolytic cells, is broadly expressed by lymphocytes following HIV-1 infection

Supplemental data

An essential role for IL-17 in preventing pathogen-initiated bone destruction: recruitment of neutrophils to inflamed bone requires IL-17 receptor–dependent signals

Jeffrey J. Yu,Matthew J. Ruddy,Grace C. Wong,Cornelia Sfintescu,Pamela J. Baker,Jeffrey B. Smith,Richard T. Evans,Sarah L. Gaffen

View Articletitled, An essential role for IL-17 in preventing pathogen-initiated bone destruction: recruitment of neutrophils to inflamed bone requires IL-17 receptor–dependent signals

Keratinocyte growth factor (KGF) enhances postnatal T-cell development via enhancements in proliferation and function of thymic epithelial cells

Simona W. Rossi,Lukas T. Jeker,Tomoo Ueno,Sachiyo Kuse,Marcel P. Keller,Saulius Zuklys,Andrei V. Gudkov,Yousuke Takahama,Werner Krenger,Bruce R. Blazar,Georg A. Holländer

View Articletitled, Keratinocyte growth factor (KGF) enhances postnatal T-cell development via enhancements in proliferation and function of thymic epithelial cells

Inhibitory effect of tumor cell–derived lactic acid on human T cells

Karin Fischer,Petra Hoffmann,Simon Voelkl,Norbert Meidenbauer,Julia Ammer,Matthias Edinger,Eva Gottfried,Sabine Schwarz,Gregor Rothe,Sabine Hoves,Kathrin Renner,Birgit Timischl,Andreas Mackensen,Leoni Kunz-Schughart,Reinhard Andreesen,Stefan W. Krause,Marina Kreutz

View Articletitled, Inhibitory effect of tumor cell–derived lactic acid on human T cells

Supplemental data

A newly established murine immature dendritic cell line can be differentiated into a mature state, but exerts tolerogenic function upon maturation in the presence of glucocorticoid

Matthias Bros,Frank Jährling,Andrea Renzing,Nadine Wiechmann,Ngoc-Anh Dang,Arne Sutter,Ralf Ross,Jürgen Knop,Stephan Sudowe,Angelika B. Reske-Kunz

View Articletitled, A newly established murine immature dendritic cell line can be differentiated into a mature state, but exerts tolerogenic function upon maturation in the presence of glucocorticoid

Effective graft depletion of MiHAg T-cell specificities and consequences for graft-versus-host disease

Moniek A. de Witte,Mireille Toebes,Ji-Ying Song,Monika C. Wolkers,Ton N. M. Schumacher

View Articletitled, Effective graft depletion of MiHAg T-cell specificities and consequences for graft-versus-host disease

Supplemental data

B cells and T cells are critical for the preservation of bone homeostasis and attainment of peak bone mass in vivo

Yan Li,Gianluca Toraldo,Aimin Li,Xiaoying Yang,Hongying Zhang,Wei-Ping Qian,M. Neale Weitzmann

View Articletitled, B cells and T cells are critical for the preservation of bone homeostasis and attainment of peak bone mass in vivo

Nur77 converts phenotype of Bcl-B, an antiapoptotic protein expressed in plasma cells and myeloma

Frederic Luciano,Maryla Krajewska,Paulina Ortiz-Rubio,Stan Krajewski,Dayong Zhai,Benjamin Faustin,Jean-Marie Bruey,Beatrice Bailly-Maitre,Alan Lichtenstein,Siva Kumar Kolluri,Arnold C. Satterthwait,Xiao-Kun Zhang,John C. Reed

View Articletitled, Nur77 converts phenotype of Bcl-B, an antiapoptotic protein expressed in plasma cells and myeloma

Supplemental data

Stimulation of P2 receptors causes release of IL-1β–loaded microvesicles from human dendritic cells

Cinzia Pizzirani,Davide Ferrari,Paola Chiozzi,Elena Adinolfi,Dorianna Sandonà,Erika Savaglio,Francesco Di Virgilio

View Articletitled, Stimulation of P2 receptors causes release of IL-1β–loaded microvesicles from human dendritic cells

Supplemental data

Vitamin A potentiates CpG-mediated memory B-cell proliferation and differentiation: involvement of early activation of p38MAPK

Aase Ertesvag,Hans-Christian Aasheim,Soheil Naderi,Heidi Kiil Blomhoff

View Articletitled, Vitamin A potentiates CpG-mediated memory B-cell proliferation and differentiation: involvement of early activation of p38MAPK

Differential effects of IL-21 and IL-15 on perforin expression, lysosomal degranulation, and proliferation in CD8 T cells of patients with human immunodeficiency virus-1 (HIV)

Lesley White,Subramaniam Krishnan,Natasa Strbo,Huanliang Liu,Michael A. Kolber,Mathias G. Lichtenheld,Rajendra N. Pahwa,Savita Pahwa

View Articletitled, Differential effects of IL-21 and IL-15 on perforin expression, lysosomal degranulation, and proliferation in CD8 T cells of patients with human immunodeficiency virus-1 (HIV)

Antiendothelial cell antibodies mediate enhanced leukocyte adhesion to cytokine-activated endothelial cells through a novel mechanism requiring cooperation between FcγRIIa and CXCR1/2

Oliver J. Florey,Michael Johns,Olubukola O. Esho,Justin C. Mason,Dorian O. Haskard

View Articletitled, Antiendothelial cell antibodies mediate enhanced leukocyte adhesion to cytokine-activated endothelial cells through a novel mechanism requiring cooperation between FcγRIIa and CXCR1/2

TLR ligands differentially affect uptake and presentation of cellular antigens

Markus Michael Weck,Frank Grünebach,Daniela Werth,Christian Sinzger,Anita Bringmann,Peter Brossart

View Articletitled, TLR ligands differentially affect uptake and presentation of cellular antigens

Supplemental data

NEOPLASIA

The C/EBPδ tumor suppressor is silenced by hypermethylation in acute myeloid leukemia

Shuchi Agrawal,Wolf-Karsten Hofmann,Nicola Tidow,Mathias Ehrich,Dirk van den Boom,Steffen Koschmieder,Wolfgang E. Berdel,Hubert Serve,Carsten Müller-Tidow

View Articletitled, The C/EBPδ tumor suppressor is silenced by hypermethylation in acute myeloid leukemia

Supplemental data

Myeloproliferative disease induced by TEL-PDGFRB displays dynamic range sensitivity to Stat5 gene dosage

Jennifer A. Cain,Zhifu Xiang,Julie O'Neal,Friederike Kreisel,AnnaLynn Colson,Hui Luo,Lothar Hennighausen,Michael H. Tomasson

View Articletitled, Myeloproliferative disease induced by TEL-PDGFRB displays dynamic range sensitivity to Stat5 gene dosage

Supplemental data

Targeting aurora kinases as therapy in multiple myeloma

Yijiang Shi,Tony Reiman,Weiqun Li,Christopher A. Maxwell,Subrata Sen,Linda Pilarski,Tracy R. Daniels,Manuel L. Penichet,Rick Feldman,Alan Lichtenstein

View Articletitled, Targeting aurora kinases as therapy in multiple myeloma

Clinical quantitation of diagnostic and predictive gene expression levels in follicular and diffuse large B-cell lymphoma by RT-PCR gene expression profiling
Clinical Trials & Observations

Ebrahim Sakhinia,Caroline Glennie,Judith A. Hoyland,Lia P. Menasce,Gerard Brady,Crispin Miller,John A. Radford,Richard J. Byers

View Articletitled, Clinical quantitation of diagnostic and predictive gene expression levels in follicular and diffuse large B-cell lymphoma by RT-PCR gene expression profiling

Supplemental data

Genomewide identification of prednisolone-responsive genes in acute lymphoblastic leukemia cells

Wim J. E. Tissing,Monique L. den Boer,Jules P. P. Meijerink,Renee X. Menezes,Sigrid Swagemakers,Peter J. van der Spek,Stephen E. Sallan,Scott A. Armstrong,Rob Pieters

View Articletitled, Genomewide identification of prednisolone-responsive genes in acute lymphoblastic leukemia cells

Polymorphisms in DNA repair genes and therapeutic outcomes of AML patients from SWOG clinical trials
Clinical Trials & Observations

Nataliya Kuptsova,Kenneth J. Kopecky,John Godwin,Jeanne Anderson,Ashraful Hoque,Cheryl L. Willman,Marilyn L. Slovak,Christine B. Ambrosone

View Articletitled, Polymorphisms in DNA repair genes and therapeutic outcomes of AML patients from SWOG clinical trials

K-Ras^G12D expression induces hyperproliferation and aberrant signaling in primary hematopoietic stem/progenitor cells

Margaret E. M. Van Meter,Ernesto Díaz-Flores,Joehleen A. Archard,Emmanuelle Passegué,Jonathan M. Irish,Nikesh Kotecha,Garry P. Nolan,Kevin Shannon,Benjamin S. Braun

View Articletitled, K-RasG12D expression induces hyperproliferation and aberrant signaling in primary hematopoietic stem/progenitor cells

Supplemental data

Integrated molecular profiling of SOD2 expression in multiple myeloma

Elaine M. Hurt,Suneetha B. Thomas,Benjamin Peng,William L. Farrar

View Articletitled, Integrated molecular profiling of SOD2 expression in multiple myeloma

Supplemental data

A leukemia fusion protein attenuates the spindle checkpoint and promotes aneuploidy

Anita Boyapati,Ming Yan,Luke F. Peterson,Joseph R. Biggs,Michelle M. Le Beau,Dong-Er Zhang

View Articletitled, A leukemia fusion protein attenuates the spindle checkpoint and promotes aneuploidy

Supplemental data

Pre-TCR expression cooperates with TEL-JAK2 to transform immature thymocytes and induce T-cell leukemia

Nuno R. dos Santos,David S. Rickman,Aurélien de Reynies,Françoise Cormier,Maryvonne Williame,Camille Blanchard,Marc-Henri Stern,Jacques Ghysdael

View Articletitled, Pre-TCR expression cooperates with TEL-JAK2 to transform immature thymocytes and induce T-cell leukemia

Supplemental data

NF-κB–independent down-regulation of XIAP by bortezomib sensitizes HL B cells against cytotoxic drugs

Hamid Kashkar,Anke Deggerich,Jens-Michael Seeger,Benjamin Yazdanpanah,Katja Wiegmann,Dirk Haubert,Carola Pongratz,Martin Krönke

View Articletitled, NF-κB–independent down-regulation of XIAP by bortezomib sensitizes HL B cells against cytotoxic drugs

Temporal genetic program following B-cell receptor cross-linking: altered balance between proliferation and death in healthy and malignant B cells

Laurent D. Vallat,Yuhyun Park,Cheng Li,John G. Gribben

View Articletitled, Temporal genetic program following B-cell receptor cross-linking: altered balance between proliferation and death in healthy and malignant B cells

Supplemental data

Trib1 and Evi1 cooperate with Hoxa and Meis1 in myeloid leukemogenesis

Guang Jin,Yukari Yamazaki,Miki Takuwa,Tomoko Takahara,Keiko Kaneko,Takeshi Kuwata,Satoshi Miyata,Takuro Nakamura

View Articletitled, Trib1 and Evi1 cooperate with Hoxa and Meis1 in myeloid leukemogenesis

Supplemental data

MEK1/2 inhibitors sensitize Bcr/Abl⁺ human leukemia cells to the dual Abl/Src inhibitor BMS-354/825

Tri K. Nguyen,Mohamed Rahmani,Hisashi Harada,Paul Dent,Steven Grant

View Articletitled, MEK1/2 inhibitors sensitize Bcr/Abl+ human leukemia cells to the dual Abl/Src inhibitor BMS-354/825

Nilotinib exerts equipotent antiproliferative effects to imatinib and does not induce apoptosis in CD34⁺ CML cells
Brief Report

Heather G. Jørgensen,Elaine K. Allan,Niove E. Jordanides,Joanne C. Mountford,Tessa L. Holyoake

View Articletitled, Nilotinib exerts equipotent antiproliferative effects to imatinib and does not induce apoptosis in CD34+ CML cells

Flt3 is dispensable to the Hoxa9/Meis1 leukemogenic cooperation
Brief Report

Ester Morgado,Stéphanie Albouhair,Catherine Lavau

View Articletitled, Flt3 is dispensable to the Hoxa9/Meis1 leukemogenic cooperation

Supplemental data

Concurrent transcriptional deregulation of AML1/RUNX1 and GATA factors by the AML1-TRPS1 chimeric gene in t(8;21)(q24;q22) acute myeloid leukemia
Brief Report

Norio Asou,Masatoshi Yanagida,Liqun Huang,Masayuki Yamamoto,Katsuya Shigesada,Hiroaki Mitsuya,Yoshiaki Ito,Motomi Osato

View Articletitled, Concurrent transcriptional deregulation of AML1/RUNX1 and GATA factors by the AML1-TRPS1 chimeric gene in t(8;21)(q24;q22) acute myeloid leukemia

Supplemental data

PHAGOCYTES

Tumor suppressor PTEN is a physiologic suppressor of chemoattractant-mediated neutrophil functions

Kulandayan K. Subramanian,Yonghui Jia,Daocheng Zhu,Benjamin T. Simms,Hakryul Jo,Hidenori Hattori,Jian You,Joseph P. Mizgerd,Hongbo R. Luo

View Articletitled, Tumor suppressor PTEN is a physiologic suppressor of chemoattractant-mediated neutrophil functions

Supplemental data

RED CELLS

Hepcidin antimicrobial peptide transgenic mice exhibit features of the anemia of inflammation

Cindy N. Roy,Howard H. Mak,Imo Akpan,Grigoriy Losyev,David Zurakowski,Nancy C. Andrews

View Articletitled, Hepcidin antimicrobial peptide transgenic mice exhibit features of the anemia of inflammation

Iron chelation regulates cyclin D1 expression via the proteasome: a link to iron deficiency–mediated growth suppression

Effie Nurtjahja-Tjendraputra,Dong Fu,Juanita M. Phang,Des R. Richardson

View Articletitled, Iron chelation regulates cyclin D1 expression via the proteasome: a link to iron deficiency–mediated growth suppression

STEM CELLS IN HEMATOLOGY

MMP-2, MT1-MMP, and TIMP-2 are essential for the invasive capacity of human mesenchymal stem cells: differential regulation by inflammatory cytokines

Christian Ries,Virginia Egea,Marisa Karow,Helmut Kolb,Marianne Jochum,Peter Neth

View Articletitled, MMP-2, MT1-MMP, and TIMP-2 are essential for the invasive capacity of human mesenchymal stem cells: differential regulation by inflammatory cytokines

TRANSPLANTATION

HLA mismatching within or outside of cross-reactive groups (CREGs) is associated with similar outcomes after unrelated hematopoietic stem cell transplantation
Clinical Trials & Observations

Judith A. Wade,Carolyn Katovich Hurley,Steven K. Takemoto,John Thompson,Stella M. Davies,Thomas C. Fuller,Glenn Rodey,Dennis L. Confer,Harriet Noreen,Michael Haagenson,Fangyu Kan,John Klein,Mary Eapen,Stephen Spellman,Craig Kollman

View Articletitled, HLA mismatching within or outside of cross-reactive groups (CREGs) is associated with similar outcomes after unrelated hematopoietic stem cell transplantation

New differentiation pathway for double-negative regulatory T cells that regulates the magnitude of immune responses

Dong Zhang,Wei Yang,Nicolas Degauque,Yan Tian,Allison Mikita,Xin Xiao Zheng

View Articletitled, New differentiation pathway for double-negative regulatory T cells that regulates the magnitude of immune responses

Supplemental data

Donor T-cell alloreactivity against host thymic epithelium limits T-cell development after bone marrow transplantation

Mathias M. Hauri-Hohl,Marcel P. Keller,Jason Gill,Katrin Hafen,Esther Pachlatko,Thomas Boulay,Annick Peter,Georg A. Holländer,Werner Krenger

View Articletitled, Donor T-cell alloreactivity against host thymic epithelium limits T-cell development after bone marrow transplantation

Supplemental data

Multiple myeloma–reactive T cells recognize an activation-induced minor histocompatibility antigen encoded by the ATP-dependent interferon-responsive (ADIR) gene

Cornelis A. M. van Bergen,Michel G. D. Kester,Inge Jedema,Mirjam H. M. Heemskerk,Simone A. P. van Luxemburg-Heijs,Freke M. Kloosterboer,W. A. Erik Marijt,Arnoud H. de Ru,M. Ron Schaafsma,Roel Willemze,Peter A. van Veelen,J. H. Frederik Falkenburg

View Articletitled, Multiple myeloma–reactive T cells recognize an activation-induced minor histocompatibility antigen encoded by the ATP-dependent interferon-responsive (ADIR) gene

Selective targeting of the LIGHT-HVEM costimulatory system for the treatment of graft-versus-host disease

Yanhui Xu,Andrew S. Flies,Dallas B. Flies,Gefeng Zhu,Sudarshan Anand,Sarah J. Flies,Haiying Xu,Robert A. Anders,Wayne W. Hancock,Lieping Chen,Koji Tamada

View Articletitled, Selective targeting of the LIGHT-HVEM costimulatory system for the treatment of graft-versus-host disease

Supplemental data

CORRESPONDENCE

The interaction between leukocytosis and other risk factors for thrombosis in essential thrombocythemia
Clinical Trials & Observations

Ayalew Tefferi,Naseema Gangat,Alexandra Wolanskyj

View Articletitled, The interaction between leukocytosis and other risk factors for thrombosis in essential thrombocythemia

Why make a diagnosis?

Richard Lipton

View Articletitled, Why make a diagnosis?

Response: Diagnosing VWD type 1: when is it useful and when illogical?

J. Evan Sadler

View Articletitled, Response: Diagnosing VWD type 1: when is it useful and when illogical?

Myelofibrosis evolving during imatinib treatment of a chronic myeloproliferative disease with coexisting BCR-ABL translocation and JAK2^V617F mutation

Kais Hussein,Oliver Bock,Anna Seegers,Michael Flasshove,Felicitas Henneke,Guntram Buesche,Hans Heinrich Kreipe

View Articletitled, Myelofibrosis evolving during imatinib treatment of a chronic myeloproliferative disease with coexisting BCR-ABL translocation and JAK2V617F mutation

Issue Archive

Table of Contents

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

Endorepellin, the C-terminal angiostatic module of perlecan, enhances collagen-platelet responses via the α2β1-integrin receptor Brief Report

INSIDE BLOOD

BLOOD WORK

CHEMOKINES, CYTOKINES, AND INTERLEUKINS

ERRATUM

CLINICAL TRIALS AND OBSERVATIONS

Results of a HOVON/SAKK donor versus no-donor analysis of myeloablative HLA-identical sibling stem cell transplantation in first remission acute myeloid leukemia in young and middle-aged adults: benefits for whom? Clinical Trials & Observations

Progression to end-stage liver disease in patients with inherited bleeding disorders and hepatitis C: an international, multicenter cohort study Clinical Trials & Observations

Cladribine in a weekly versus daily schedule for untreated active hairy cell leukemia: final report from the Polish Adult Leukemia Group (PALG) of a prospective, randomized, multicenter trial Clinical Trials & Observations Brief Report

HEMATOPOIESIS

IMMUNOBIOLOGY

NEOPLASIA

Clinical quantitation of diagnostic and predictive gene expression levels in follicular and diffuse large B-cell lymphoma by RT-PCR gene expression profiling Clinical Trials & Observations

Polymorphisms in DNA repair genes and therapeutic outcomes of AML patients from SWOG clinical trials Clinical Trials & Observations

Nilotinib exerts equipotent antiproliferative effects to imatinib and does not induce apoptosis in CD34+ CML cells Brief Report

Flt3 is dispensable to the Hoxa9/Meis1 leukemogenic cooperation Brief Report

Concurrent transcriptional deregulation of AML1/RUNX1 and GATA factors by the AML1-TRPS1 chimeric gene in t(8;21)(q24;q22) acute myeloid leukemia Brief Report

PHAGOCYTES

RED CELLS

STEM CELLS IN HEMATOLOGY

TRANSPLANTATION

HLA mismatching within or outside of cross-reactive groups (CREGs) is associated with similar outcomes after unrelated hematopoietic stem cell transplantation Clinical Trials & Observations

CORRESPONDENCE

The interaction between leukocytosis and other risk factors for thrombosis in essential thrombocythemia Clinical Trials & Observations

Cover Image

Email alerts

ASH Publications

American Society of Hematology

This Feature Is Available To Subscribers Only

Endorepellin, the C-terminal angiostatic module of perlecan, enhances collagen-platelet responses via the α2β1-integrin receptor
Brief Report

Results of a HOVON/SAKK donor versus no-donor analysis of myeloablative HLA-identical sibling stem cell transplantation in first remission acute myeloid leukemia in young and middle-aged adults: benefits for whom?
Clinical Trials & Observations

Progression to end-stage liver disease in patients with inherited bleeding disorders and hepatitis C: an international, multicenter cohort study
Clinical Trials & Observations

Cladribine in a weekly versus daily schedule for untreated active hairy cell leukemia: final report from the Polish Adult Leukemia Group (PALG) of a prospective, randomized, multicenter trial
Clinical Trials & Observations Brief Report

Clinical quantitation of diagnostic and predictive gene expression levels in follicular and diffuse large B-cell lymphoma by RT-PCR gene expression profiling
Clinical Trials & Observations

Polymorphisms in DNA repair genes and therapeutic outcomes of AML patients from SWOG clinical trials
Clinical Trials & Observations

Nilotinib exerts equipotent antiproliferative effects to imatinib and does not induce apoptosis in CD34⁺ CML cells
Brief Report

Flt3 is dispensable to the Hoxa9/Meis1 leukemogenic cooperation
Brief Report

Concurrent transcriptional deregulation of AML1/RUNX1 and GATA factors by the AML1-TRPS1 chimeric gene in t(8;21)(q24;q22) acute myeloid leukemia
Brief Report

HLA mismatching within or outside of cross-reactive groups (CREGs) is associated with similar outcomes after unrelated hematopoietic stem cell transplantation
Clinical Trials & Observations

The interaction between leukocytosis and other risk factors for thrombosis in essential thrombocythemia
Clinical Trials & Observations