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Unrelated transplants in aplastic anemia: are we making progress?
Alternating versus concurrent schedules of imatinib and chemotherapy as front-line therapy for Philadelphia-positive acute lymphoblastic leukemia (Ph+ALL)
Survival advantage from imatinib compared with the combination interferon-α plus cytarabine in chronic-phase chronic myelogenous leukemia: historical comparison between two phase 3 trials
Optimization of conditioning for marrow transplantation from unrelated donors for patients with aplastic anemia after failure of immunosuppressive therapy
Predictive factors for thrombosis and major bleeding in an observational study in 181 patients with heparin-induced thrombocytopenia treated with lepirudin
International Working Group (IWG) consensus criteria for treatment response in myelofibrosis with myeloid metaplasia, for the IWG for Myelofibrosis Research and Treatment (IWG-MRT)
The Follicular Lymphoma International Prognostic Index (FLIPI) separates high-risk from intermediate- or low-risk patients with advanced-stage follicular lymphoma treated front-line with rituximab and the combination of cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) with respect to treatment outcome
Constitutive activation of STAT5 and Bcl-xL overexpression can induce endogenous erythroid colony formation in human primary cells
Frequent gain of chromosome band 1q21 in plasma-cell dyscrasias detected by fluorescence in situ hybridization: incidence increases from MGUS to relapsed myeloma and is related to prognosis and disease progression following tandem stem-cell transplantation
Issue Archive
September 1 2006
Table of Contents
INSIDE BLOOD
CLINICAL TRIALS AND OBSERVATIONS
Unrelated transplants in aplastic anemia: are we making progress?
Clinical Trials & Observations
BLOOD WORK
PERSPECTIVES
REVIEW ARTICLES
CHEMOKINES, CYTOKINES, AND INTERLEUKINS
Cell death provoked by loss of interleukin-3 signaling is independent of Bad, Bim, and PI3 kinase, but depends in part on Puma
Paul G. Ekert,Anissa M. Jabbour,Anand Manoharan,Jacki E. Heraud,Jai Yu,Miha Pakusch,Ewa M. Michalak,Priscilla N. Kelly,Bernard Callus,Thomas Kiefer,Anne Verhagen,John Silke,Andreas Strasser,Christoph Borner,David L. Vaux
CLINICAL TRIALS AND OBSERVATIONS
Alternating versus concurrent schedules of imatinib and chemotherapy as front-line therapy for Philadelphia-positive acute lymphoblastic leukemia (Ph+ALL)
Clinical Trials & Observations
Barbara Wassmann,Heike Pfeifer,Nicola Goekbuget,Dietrich W. Beelen,Joachim Beck,Matthias Stelljes,Martin Bornhäuser,Albrecht Reichle,Jolanta Perz,Rainer Haas,Arnold Ganser,Mathias Schmid,Lothar Kanz,Georg Lenz,Martin Kaufmann,Anja Binckebanck,Patrick Brück,Regina Reutzel,Harald Gschaidmeier,Stefan Schwartz,Dieter Hoelzer,Oliver G. Ottmann
Survival advantage from imatinib compared with the combination interferon-α plus cytarabine in chronic-phase chronic myelogenous leukemia: historical comparison between two phase 3 trials
Clinical Trials & Observations
Lydia Roy,Joëlle Guilhot,Tillmann Krahnke,Agnès Guerci-Bresler,Brian J. Druker,Richard A. Larson,Steve O'Brien,Charlene So,Giorgio Massimini,François Guilhot
Optimization of conditioning for marrow transplantation from unrelated donors for patients with aplastic anemia after failure of immunosuppressive therapy
Clinical Trials & Observations
H. Joachim Deeg,Margaret O'Donnell,Jakub Tolar,Rajni Agarwal,Richard E. Harris,Stephen A. Feig,Mary C. Territo,Robert H. Collins,Peter A. McSweeney,Edward A. Copelan,Shakila P. Khan,Ann Woolfrey,Barry Storer
Predictive factors for thrombosis and major bleeding in an observational study in 181 patients with heparin-induced thrombocytopenia treated with lepirudin
Clinical Trials & Observations
Bernard Tardy,Thomas Lecompte,Françoise Boelhen,Brigitte Tardy-Poncet,Ismaïl Elalamy,Pierre Morange,Yves Gruel,Martine Wolf,Dominique François,Evelyne Racadot,Philippe Camarasa,Marie Thérèse Blouch,Françoise Nguyen,Sylvie Doubine,Fabienne Dutrillaux,Martine Alhenc-Gelas,Isabelle Martin-Toutain,Anne Bauters,Patrick Ffrench,Emmanuel de Maistre,Lélia Grunebaum,Christine Mouton,Marie G. Huisse,Michèle Gouault-Heilmann,Veronique Lucke,for the GEHT-HIT study group
International Working Group (IWG) consensus criteria for treatment response in myelofibrosis with myeloid metaplasia, for the IWG for Myelofibrosis Research and Treatment (IWG-MRT)
Clinical Trials & Observations
Ayalew Tefferi,Giovanni Barosi,Ruben A. Mesa,Francisco Cervantes,H. Joachim Deeg,John T. Reilly,Srdan Verstovsek,Brigitte Dupriez,Richard T. Silver,Olatoyosi Odenike,Jorge Cortes,Martha Wadleigh,Lawrence A. Solberg, Jr,John K. Camoriano,Heinz Gisslinger,Pierre Noel,Juergen Thiele,James W. Vardiman,Ronald Hoffman,Nicholas C. P. Cross,D. Gary Gilliland,Hagop Kantarjian
The Follicular Lymphoma International Prognostic Index (FLIPI) separates high-risk from intermediate- or low-risk patients with advanced-stage follicular lymphoma treated front-line with rituximab and the combination of cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) with respect to treatment outcome
Clinical Trials & Observations
Brief Report
Christian Buske,Eva Hoster,Martin Dreyling,Joerg Hasford,Michael Unterhalt,Wolfgang Hiddemann,for the German Low Grade Lymphoma Study Group (GLSG)
HEMATOPOIESIS
Tetracycline-controlled transgenic targeting from the SCL locus directs conditional expression to erythrocytes, megakaryocytes, granulocytes, and c-kit-expressing lineage-negative hematopoietic cells
Ernesto Bockamp,Cecilia Antunes,Marko Maringer,Rosario Heck,Katrin Presser,Sven Beilke,Svetlana Ohngemach,Rudiger Alt,Michael Cross,Rolf Sprengel,Udo Hartwig,Bernd Kaina,Steffen Schmitt,Leonid Eshkind
Identification of Y589 and Y599 in the juxtamembrane domain of Flt3 as ligand-induced autophosphorylation sites involved in binding of Src family kinases and the protein tyrosine phosphatase SHP2
Elke Heiss,Kristina Masson,Christina Sundberg,Malin Pedersen,Jianmin Sun,Susanne Bengtsson,Lars Rönnstrand
Constitutive activation of STAT5 and Bcl-xL overexpression can induce endogenous erythroid colony formation in human primary cells
Brief Report
Loïc Garçon,Christine Rivat,Chloé James,Catherine Lacout,Valérie Camara-Clayette,Valérie Ugo,Yann Lecluse,Annelise Bennaceur-Griscelli,William Vainchenker
HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY
IMMUNOBIOLOGY
IL-2 regulates FOXP3 expression in human CD4+CD25+ regulatory T cells through a STAT-dependent mechanism and induces the expansion of these cells in vivo
Emmanuel Zorn,Erik A. Nelson,Mehrdad Mohseni,Fabrice Porcheray,Haesook Kim,Despina Litsa,Roberto Bellucci,Elke Raderschall,Christine Canning,Robert J. Soiffer,David A. Frank,Jerome Ritz
NEOPLASIA
Loss of inhibitory semaphorin 3A (SEMA3A) autocrine loops in bone marrow endothelial cells of patients with multiple myeloma
Angelo Vacca,Claudio Scavelli,Guido Serini,Giulia Di Pietro,Teresa Cirulli,Francesca Merchionne,Domenico Ribatti,Federico Bussolino,Diego Guidolin,Giovanna Piaggio,Andrea Bacigalupo,Franco Dammacco
Independent confirmation of a prognostic gene-expression signature in adult acute myeloid leukemia with a normal karyotype: a Cancer and Leukemia Group B study
Michael D. Radmacher,Guido Marcucci,Amy S. Ruppert,Krzysztof Mrózek,Susan P. Whitman,James W. Vardiman,Peter Paschka,Tamara Vukosavljevic,Claudia D. Baldus,Jonathan E. Kolitz,Michael A. Caligiuri,Richard A. Larson,Clara D. Bloomfield
Multiple myeloma cell survival relies on high activity of protein kinase CK2
Francesco A. Piazza,Maria Ruzzene,Carmela Gurrieri,Barbara Montini,Luca Bonanni,Gino Chioetto,Giovanni Di Maira,Francesca Barbon,Anna Cabrelle,Renato Zambello,Fausto Adami,Livio Trentin,Lorenzo A. Pinna,Gianpietro Semenzato
Frequent gain of chromosome band 1q21 in plasma-cell dyscrasias detected by fluorescence in situ hybridization: incidence increases from MGUS to relapsed myeloma and is related to prognosis and disease progression following tandem stem-cell transplantation
Clinical Trials & Observations
Ichiro Hanamura,James P. Stewart,Yongsheng Huang,Fenghuang Zhan,Madhumita Santra,Jeffrey R. Sawyer,Klaus Hollmig,Maurizio Zangarri,Mauricio Pineda-Roman,Frits van Rhee,Federica Cavallo,Bart Burington,John Crowley,Guido Tricot,Bart Barlogie,John D. Shaughnessy, Jr
Mantle cell lymphoma cells express predominantly cyclin D1a isoform and are highly sensitive to selective inhibition of CDK4 kinase activity
Michal Marzec,Monika Kasprzycka,Raymond Lai,Andrew B. Gladden,Pawel Wlodarski,Ewa Tomczak,Peter Nowell,Samuel E. DePrimo,Seth Sadis,Stephen Eck,Stephen J. Schuster,J. Alan Diehl,Mariusz A. Wasik
PHAGOCYTES
TRANSPLANTATION
CORRESPONDENCE
ERRATA
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