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Sequential multiagent chemotherapy is not superior to high-dose cytarabine alone as postremission intensification therapy for acute myeloid leukemia in adults under 60 years of age: Cancer and Leukemia Group B Study 9222
Quantitative PCR of bone marrow BCL2/IgH+ cells at diagnosis predicts treatment response and long-term outcome in follicular non-Hodgkin lymphoma
A comprehensive genetic classification of adult acute lymphoblastic leukemia (ALL): analysis of the GIMEMA 0496 protocol
Genetic subtypes of familial hemophagocytic lymphohistiocytosis: correlations with clinical features and cytotoxic T lymphocyte/natural killer cell functions
The effect of first-line imatinib interim therapy on the outcome of allogeneic stem cell transplantation in adults with newly diagnosed Philadelphia chromosome–positive acute lymphoblastic leukemia
A common Fanconi anemia mutation in black populations of sub-Saharan Africa
A functional single-nucleotide polymorphism of the G-CSF receptor gene predisposes individuals to high-risk myelodysplastic syndrome
Farnesyltransferase inhibitor tipifarnib (R115777) preferentially inhibits in vitro autonomous erythropoiesis of polycythemia vera patient cells
Issue Archive
Table of Contents
INSIDE BLOOD
BLOOD WORK
PLENARY PAPERS
ERRATA
CHEMOKINES
CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS
Sequential multiagent chemotherapy is not superior to high-dose cytarabine alone as postremission intensification therapy for acute myeloid leukemia in adults under 60 years of age: Cancer and Leukemia Group B Study 9222
Clinical Trials & Observations
Joseph O. Moore,Stephen L. George,Richard K. Dodge,Philip C. Amrein,Bayard L. Powell,Jonathan E. Kolitz,Maria R. Baer,Frederick R. Davey,Clara D. Bloomfield,Richard A. Larson,Charles A. Schiffer
Quantitative PCR of bone marrow BCL2/IgH+ cells at diagnosis predicts treatment response and long-term outcome in follicular non-Hodgkin lymphoma
Clinical Trials & Observations
Alessandro Rambaldi,Emanuela Carlotti,Elena Oldani,Irene Della Starza,Michele Baccarani,Sergio Cortelazzo,Francesco Lauria,Luca Arcaini,Enrica Morra,Alessandro Pulsoni,Luigi Rigacci,Maurizio Rupolo,Francesco Zaja,Pier Luigi Zinzani,Tiziano Barbui,Robert Foa
A comprehensive genetic classification of adult acute lymphoblastic leukemia (ALL): analysis of the GIMEMA 0496 protocol
Clinical Trials & Observations
Marco Mancini,Daniela Scappaticci,Giuseppe Cimino,Mauro Nanni,Valentina Derme,Loredana Elia,Agostino Tafuri,Marco Vignetti,Antonella Vitale,Antonio Cuneo,Gianluigi Castoldi,Giuseppe Saglio,Fabrizio Pane,Cristina Mecucci,Andrea Camera,Giorgina Specchia,Alessandra Tedeschi,Francesco Di Raimondo,Giuseppe Fioritoni,Francesco Fabbiano,Filippo Marmont,Felicetto Ferrara,Nicola Cascavilla,Giuseppe Todeschini,Francesco Nobile,Maria Grazia Kropp,Pietro Leoni,Antonio Tabilio,Mario Luppi,Luciana Annino,Franco Mandelli,Robin Foà
Genetic subtypes of familial hemophagocytic lymphohistiocytosis: correlations with clinical features and cytotoxic T lymphocyte/natural killer cell functions
Clinical Trials & Observations
Eiichi Ishii,Ikuyo Ueda,Ryutaro Shirakawa,Ken Yamamoto,Hisanori Horiuchi,Shouichi Ohga,Kenji Furuno,Akira Morimoto,Miyoko Imayoshi,Yoshiyasu Ogata,Masafumi Zaitsu,Masahiro Sako,Kenichi Koike,Akifumi Sakata,Hidetoshi Takada,Toshiro Hara,Shinsaku Imashuku,Takehiko Sasazuki,Masaki Yasukawa
The effect of first-line imatinib interim therapy on the outcome of allogeneic stem cell transplantation in adults with newly diagnosed Philadelphia chromosome–positive acute lymphoblastic leukemia
Clinical Trials & Observations
Seok Lee,Yoo-Jin Kim,Chang-Ki Min,Hee-Je Kim,Ki-Sung Eom,Dong-Wook Kim,Jong-Wook Lee,Woo-Sung Min,Chun-Choo Kim
GENE THERAPY
Ex vivo culture of Fancc-/- stem/progenitor cells predisposes cells to undergo apoptosis, and surviving stem/progenitor cells display cytogenetic abnormalities and an increased risk of malignancy
Xiaxin Li,Michelle M. Le Beau,Samantha Ciccone,Feng-Chun Yang,Brian Freie,Shi Chen,Jin Yuan,Ping Hong,Attilio Orazi,Laura S. Haneline,D. Wade Clapp
HEMATOPOIESIS
A pathobiologic pathway linking thrombopoietin, GATA-1, and TGF-β1 in the development of myelofibrosis
Alessandro M. Vannucchi,Lucia Bianchi,Francesco Paoletti,Alessandro Pancrazzi,Eugenio Torre,Mitsuo Nishikawa,Maria Zingariello,Angela Di Baldassarre,Rosa Alba Rana,Rodolfo Lorenzini,Elena Alfani,Giovanni Migliaccio,Anna Rita Migliaccio
A common Fanconi anemia mutation in black populations of sub-Saharan Africa
Clinical Trials & Observations
Brief Report
Neil V. Morgan,Fahmida Essop,Ilja Demuth,Thomy de Ravel,Stander Jansen,Marc Tischkowitz,Cathryn M. Lewis,Linda Wainwright,Janet Poole,Hans Joenje,Martin Digweed,Amanda Krause,Christopher G. Mathew
HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY
Tumor necrosis factor-α–dependent expression of phosphodiesterase 2: role in endothelial hyperpermeability
Joachim Seybold,Dirk Thomas,Martin Witzenrath,Şengül Boral,Andreas C. Hocke,Alexander Bürger,Armin Hatzelmann,Hermann Tenor,Christian Schudt,Matthias Krüll,Hartwig Schütte,Stefan Hippenstiel,Norbert Suttorp
IMMUNOBIOLOGY
Uptake and presentation of hepatitis C virus–like particles by human dendritic cells
Heidi Barth,Axel Ulsenheimer,Gerd R. Pape,Helmut M. Diepolder,Marco Hoffmann,Christoph Neumann-Haefelin,Robert Thimme,Philipp Henneke,Reinhild Klein,Glaucia Paranhos-Baccalà,Erik Depla,T. Jake Liang,Hubert E. Blum,Thomas F. Baumert
Ligands for natural killer cell–activating receptors are expressed upon the maturation of normal myelomonocytic cells but at low levels in acute myeloid leukemias
Pegah Nowbakht,Mihai-Constantin S. Ionescu,Andreas Rohner,Christian P. Kalberer,Emmanuel Rossy,Lucia Mori,David Cosman,Gennaro De Libero,Aleksandra Wodnar-Filipowicz
NEOPLASIA
A functional single-nucleotide polymorphism of the G-CSF receptor gene predisposes individuals to high-risk myelodysplastic syndrome
Clinical Trials & Observations
Albert Wölfler,Stefan J. Erkeland,Claudia Bodner,Marijke Valkhof,Wilfried Renner,Christina Leitner,Werner Olipitz,Michael Pfeilstöcker,Christoph Tinchon,Werner Emberger,Werner Linkesch,Ivo P. Touw,Heinz Sill
Farnesyltransferase inhibitor tipifarnib (R115777) preferentially inhibits in vitro autonomous erythropoiesis of polycythemia vera patient cells
Brief Report
Jérôme Larghero,Nathalie Gervais,Bruno Cassinat,Jean-Didier Rain,Marie-Hélène Schlageter,Rose Ann Padua,Christine Chomienne,Philippe Rousselot
RED CELLS
TRANSPLANTATION
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