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New anticoagulants
A randomized trial of high-versus conventional-dose cytarabine in consolidation chemotherapy for adult de novo acute myeloid leukemia in first remission after induction therapy containing high-dose cytarabine
Combination immunotherapy with a CpG oligonucleotide (1018 ISS) and rituximab in patients with non-Hodgkin lymphoma: increased interferon-α/β–inducible gene expression, without significant toxicity
High incidence of occult leptomeningeal disease detected by flow cytometry in newly diagnosed aggressive B-cell lymphomas at risk for central nervous system involvement: the role of flow cytometry versus cytology
Early TCR-β and TCR-γ PCR detection of T-cell clonality indicates minimal tumor disease in lymph nodes of cutaneous T-cell lymphoma: diagnostic and prognostic implications
Deficiency of somatic hypermutation of the antibody light chain is associated with increased frequency of severe respiratory tract infection in common variable immunodeficiency
The safety and efficacy of recombinant human blood coagulation factor IX in previously untreated patients with severe or moderately severe hemophilia B
Circulating endothelial cells, von Willebrand factor, interleukin-6, and prognosis in patients with acute coronary syndromes
HCV quasispecies evolution: association with progression to end-stage liver disease in hemophiliacs infected with HCV or HCV/HIV
Fatal congenital thrombotic thrombocytopenic purpura with apparent ADAMTS13 inhibitor: in vitro inhibition of ADAMTS13 activity by hemoglobin
Mortality in sickle cell patients on hydroxyurea therapy
Increased risk of extensive chronic graft-versus-host disease after allogeneic peripheral blood stem cell transplantation using unrelated donors
High factor VIII levels in venous thromboembolism show linkage to imprinted loci on chromosomes 5 and 11
A polymorphism in the VKORC1 gene is associated with an interindividual variability in the dose-anticoagulant effect of warfarin
Distinct gene expression profiles determine molecular treatment response in childhood acute lymphoblastic leukemia
The efficiency of transfusing high doses of platelets in hematologic patients with thrombocytopenia: results of a prospective, randomized, open, blinded end point (PROBE) study
Improved survival after unrelated donor bone marrow transplantation in children with primary immunodeficiency using a reduced-intensity conditioning regimen
Issue Archive
January 15 2005
In this Issue
Table of Contents
INSIDE BLOOD
REVIEW ARTICLES
REVIEW IN TRANSLATIONAL HEMATOLOGY
New anticoagulants
Clinical Trials & Observations
CHEMOKINES
IL-8 and its CXCR1 and CXCR2 receptors participate in the control of megakaryocytic proliferation, differentiation, and ploidy in myeloid metaplasia with myelofibrosis
Sharareh Emadi,Denis Clay,Christophe Desterke,Bernadette Guerton,Eliane Maquarre,Agnès Charpentier,Claude Jasmin,Marie-Caroline Le Bousse-Kerdilès,for the French INSERM Research Network on MMM
ERRATA
CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS
A randomized trial of high-versus conventional-dose cytarabine in consolidation chemotherapy for adult de novo acute myeloid leukemia in first remission after induction therapy containing high-dose cytarabine
Clinical Trials & Observations
Kenneth F. Bradstock,Jane P. Matthews,Raymond M. Lowenthal,Heather Baxter,John Catalano,Timothy Brighton,Devinder Gill,Paul Eliadis,Douglas Joshua,Paul Cannell,Anthony P. Schwarer,Simon Durrant,Anne Gillett,Jerry Koutts,Kerry Taylor,John Bashford,Christopher Arthur,Arno Enno,Lindsay Dunlop,Jeff Szer,Michael Leahy,Surender Juneja,Graham A. R. Young,for the Australasian Leukaemia and Lymphoma Group
Combination immunotherapy with a CpG oligonucleotide (1018 ISS) and rituximab in patients with non-Hodgkin lymphoma: increased interferon-α/β–inducible gene expression, without significant toxicity
Clinical Trials & Observations
Jonathan W. Friedberg,Helen Kim,Mary McCauley,Edith M. Hessel,Paul Sims,David C. Fisher,Lee M. Nadler,Robert L. Coffman,Arnold S. Freedman
High incidence of occult leptomeningeal disease detected by flow cytometry in newly diagnosed aggressive B-cell lymphomas at risk for central nervous system involvement: the role of flow cytometry versus cytology
Clinical Trials & Observations
Upendra Hegde,Armando Filie,Richard F. Little,John E. Janik,Nicole Grant,Seth M. Steinberg,Kieron Dunleavy,Elaine S. Jaffe,Andrea Abati,Maryalice Stetler-Stevenson,Wyndham H. Wilson
Early TCR-β and TCR-γ PCR detection of T-cell clonality indicates minimal tumor disease in lymph nodes of cutaneous T-cell lymphoma: diagnostic and prognostic implications
Clinical Trials & Observations
Chalid Assaf,Michael Hummel,Matthias Steinhoff,Christoph C. Geilen,Helmut Orawa,Harald Stein,Constantin E. Orfanos
Deficiency of somatic hypermutation of the antibody light chain is associated with increased frequency of severe respiratory tract infection in common variable immunodeficiency
Clinical Trials & Observations
Pernille Andersen,Henrik Permin,Vagn Andersen,Lone Schejbel,Peter Garred,Arne Svejgaard,Torben Barington
The safety and efficacy of recombinant human blood coagulation factor IX in previously untreated patients with severe or moderately severe hemophilia B
Clinical Trials & Observations
Amy D. Shapiro,Jorge Di Paola,Alice Cohen,K. John Pasi,Margaret A. Heisel,Victor S. Blanchette,Thomas C. Abshire,W. Keith Hoots,Jeanne M. Lusher,Claude Negrier,Chantal Rothschild,David A. Roth,for the Recombinant Factor IX Study Group
Circulating endothelial cells, von Willebrand factor, interleukin-6, and prognosis in patients with acute coronary syndromes
Clinical Trials & Observations
HCV quasispecies evolution: association with progression to end-stage liver disease in hemophiliacs infected with HCV or HCV/HIV
Clinical Trials & Observations
Hongxing Qin,Norah J. Shire,Erica D. Keenan,Susan D. Rouster,M. Elaine Eyster,James J. Goedert,Margaret James Koziel,Kenneth E. Sherman,and the Multicenter Hemophilia Cohort Study Group
Fatal congenital thrombotic thrombocytopenic purpura with apparent ADAMTS13 inhibitor: in vitro inhibition of ADAMTS13 activity by hemoglobin
Clinical Trials & Observations
Brief Report
Jan-Dirk Studt,Johanna A. Kremer Hovinga,Gerhard Antoine,Martin Hermann,Manfred Rieger,Friedrich Scheiflinger,Bernhard Lämmle
Mortality in sickle cell patients on hydroxyurea therapy
Clinical Trials & Observations
Brief Report
Sule M. Bakanay,Erin Dainer,Betsy Clair,Adekunle Adekile,Lisa Daitch,Leigh Wells,Leslie Holley,David Smith,Abdullah Kutlar
Increased risk of extensive chronic graft-versus-host disease after allogeneic peripheral blood stem cell transplantation using unrelated donors
Clinical Trials & Observations
Brief Report
HEMATOPOIESIS
A novel therapeutic approach for thrombocytopenia by minibody agonist of the thrombopoietin receptor
Tetsuro Orita,Hiroyuki Tsunoda,Naohiro Yabuta,Kiyotaka Nakano,Takeshi Yoshino,Yuichi Hirata,Toshihiko Ohtomo,Jun-ichi Nezu,Hirofumi Sakumoto,Kouichiro Ono,Mikiyoshi Saito,Eiji Kumagai,Masahiko Nanami,Akihisa Kaneko,Takashi Yoshikubo,Masayuki Tsuchiya
HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY
High factor VIII levels in venous thromboembolism show linkage to imprinted loci on chromosomes 5 and 11
Clinical Trials & Observations
Mario Berger,Manuel Mattheisen,Bettina Kulle,Henriette Schmidt,Johannes Oldenburg,Heike Bickeböller,Ulrich Walter,Tom H. Lindner,Konstantin Strauch,Christian M. Schambeck
A polymorphism in the VKORC1 gene is associated with an interindividual variability in the dose-anticoagulant effect of warfarin
Clinical Trials & Observations
Giovanna D'Andrea,Rosa Lucia D'Ambrosio,Pasquale Di Perna,Massimiliano Chetta,Rosa Santacroce,Vincenzo Brancaccio,Elvira Grandone,Maurizio Margaglione
IMMUNOBIOLOGY
NEOPLASIA
Quantitative analysis of nucleoside transporter and metabolism gene expression in chronic lymphocytic leukemia (CLL): identification of fludarabine-sensitive and -insensitive populations
John R. Mackey,Carlos M. Galmarini,Kathryn A. Graham,Anil A. Joy,Alain Delmer,Laith Dabbagh,Darryl Glubrecht,Lawrence D. Jewell,Raymond Lai,Thack Lang,John Hanson,James D. Young,Helene Merle-Béral,Jacques L. Binet,Carol E. Cass,Charles Dumontet
Targeting NF-κB activation via pharmacologic inhibition of IKK2-induced apoptosis of human acute myeloid leukemia cells
Catherine Frelin,Véronique Imbert,Emmanuel Griessinger,Annie-Claude Peyron,Nathalie Rochet,Patrick Philip,Christian Dageville,Anne Sirvent,Michaël Hummelsberger,Etienne Bérard,Michel Dreano,Nicolas Sirvent,Jean-François Peyron
Distinct gene expression profiles determine molecular treatment response in childhood acute lymphoblastic leukemia
Clinical Trials & Observations
Gunnar Cario,Martin Stanulla,Bernard M. Fine,Oliver Teuffel,Nils v. Neuhoff,André Schrauder,Thomas Flohr,Beat W. Schäfer,Claus R. Bartram,Karl Welte,Brigitte Schlegelberger,Martin Schrappe
PHAGOCYTES
Proinflammatory mediators elicit secretion of the intracellular B-lymphocyte stimulator pool (BLyS) that is stored in activated neutrophils: implications for inflammatory diseases
Patrizia Scapini,Antonio Carletto,Bernardetta Nardelli,Federica Calzetti,Viktor Roschke,Flavia Merigo,Nicola Tamassia,Sara Pieropan,Domenico Biasi,Andrea Sbarbati,Silvano Sozzani,Lisa Bambara,Marco A. Cassatella
RED CELLS
TRANSFUSION MEDICINE
The efficiency of transfusing high doses of platelets in hematologic patients with thrombocytopenia: results of a prospective, randomized, open, blinded end point (PROBE) study
Clinical Trials & Observations
Brief Report
Luc Sensebé,Bruno Giraudeau,Laurent Bardiaux,Eric Deconinck,Aline Schmidt,Marie-Laure Bidet,Catherine LeNiger,Elisabeth Hardy,Catherine Babault,Delphine Senecal
TRANSPLANTATION
Improved survival after unrelated donor bone marrow transplantation in children with primary immunodeficiency using a reduced-intensity conditioning regimen
Clinical Trials & Observations
Kanchan Rao,Persis J. Amrolia,Alison Jones,Catherine M. Cale,Paru Naik,Doug King,Graham E. Davies,H. Bobby Gaspar,Paul A. Veys
Prediction of T-cell reconstitution by assessment of T-cell receptor excision circle before allogeneic hematopoietic stem cell transplantation in pediatric patients
Xiaohua Chen,Raymond Barfield,Ely Benaim,Wing Leung,James Knowles,Dawn Lawrence,Mario Otto,Sheila A. Shurtleff,Geoffrey A. M. Neale,Frederick G. Behm,Victoria Turner,Rupert Handgretinger
CORRESPONDENCE
Imatinib mesylate in the treatment of c-kit–positive acute myeloid leukemia: is this the real target?
Michele Malagola,Giovanni Martinelli,Michela Rondoni,Stefania Paolini,Stavrula Gaitani,Mario Arpinati,Pier Paolo Piccaluga,Marilina Amabile,Constanza Basi,Emanuela Ottaviani,Anna Candoni,Enrico Gottardi,Daniela Cilloni,Monica Bocchia,Giuseppe Saglio,Francesco Lauria,Renato Fanin,Giuseppe Visani,Maria Carla Marrè,Michela Maderna,Francesca Rancati,Vincenza Vinaccia,Domenico Russo,Michele Baccarani
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