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Late mortality in survivors of autologous hematopoietic-cell transplantation: report from the Bone Marrow Transplant Survivor Study
Asparagine synthetase expression is linked with l-asparaginase resistance in TEL-AML1–negative but not TEL-AML1–positive pediatric acute lymphoblastic leukemia
Failure of SCID-X1 gene therapy in older patients
Identification and functional characterization of a novel 27-bp deletion in the macroglycopeptide-coding region of the GPIBA gene resulting in platelet-type von Willebrand disease
A proportion of patients with lymphoma may harbor mutations of the perforin gene
Mantle-cell lymphoma genotypes identified with CGH to BAC microarrays define a leukemic subgroup of disease and predict patient outcome
AML1-FOG2 fusion protein in myelodysplasia
Outcomes for reduced-intensity allogeneic transplantation for multiple myeloma: an analysis of prognostic factors from the Chronic Leukaemia Working Party of the EBMT
Issue Archive
June 1 2005
In this Issue
Table of Contents
INSIDE BLOOD
BLOOD WORK
PLENARY PAPERS
PERSPECTIVES
REVIEW ARTICLES
REVIEW IN TRANSLATIONAL HEMATOLOGY
CHEMOKINES
CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS
Late mortality in survivors of autologous hematopoietic-cell transplantation: report from the Bone Marrow Transplant Survivor Study
Clinical Trials & Observations
Smita Bhatia,Leslie L. Robison,Liton Francisco,Andrea Carter,Yan Liu,Marcia Grant,K. Scott Baker,Henry Fung,James G. Gurney,Philip B. McGlave,Auayporn Nademanee,Norma K. C. Ramsay,Anthony Stein,Daniel J. Weisdorf,Stephen J. Forman
Asparagine synthetase expression is linked with l-asparaginase resistance in TEL-AML1–negative but not TEL-AML1–positive pediatric acute lymphoblastic leukemia
Clinical Trials & Observations
Brief Report
Wendy A. G. Stams,Monique L. den Boer,Amy Holleman,Inge M. Appel,H. Berna Beverloo,Elisabeth R. van Wering,Gritta E. Janka-Schaub,William E. Evans,Rob Pieters
GENE THERAPY
Leukemias following retroviral transfer of multidrug resistance 1 (MDR1) are driven by combinatorial insertional mutagenesis
Ute Modlich,Olga S. Kustikova,Manfred Schmidt,Cornelia Rudolph,Johann Meyer,Zhixiong Li,Kenji Kamino,Nils von Neuhoff,Brigitte Schlegelberger,Klaus Kuehlcke,Kevin D. Bunting,Sonja Schmidt,Annette Deichmann,Christof von Kalle,Boris Fehse,Christopher Baum
Failure of SCID-X1 gene therapy in older patients
Clinical Trials & Observations
Adrian J. Thrasher,Salima Hacein-Bey-Abina,H. Bobby Gaspar,Stephane Blanche,E. Graham Davies,Kathryn Parsley,Kimberly Gilmour,Douglas King,Steven Howe,Joanna Sinclair,Christophe Hue,Frédérique Carlier,Christof von Kalle,Geneviève de Saint Basile,Françoise le Deist,Alain Fischer,Marina Cavazzana-Calvo
HEMATOPOIESIS
HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY
Identification and functional characterization of a novel 27-bp deletion in the macroglycopeptide-coding region of the GPIBA gene resulting in platelet-type von Willebrand disease
Clinical Trials & Observations
Maha Othman,Colleen Notley,Frances Louise Lavender,Helen White,Christopher D. Byrne,David Lillicrap,Denise Frances O'Shaughnessy
Identification of a transiently exposed VE-cadherin epitope that allows for specific targeting of an antibody to the tumor neovasculature
Chad May,Jacqueline F. Doody,Rashed Abdullah,Paul Balderes,Xiaohong Xu,Chien Peter Chen,Zhenping Zhu,Lawrence Shapiro,Paul Kussie,Daniel J. Hicklin,Fang Liao,Peter Bohlen
IMMUNOBIOLOGY
A proportion of patients with lymphoma may harbor mutations of the perforin gene
Clinical Trials & Observations
Rita Clementi,Franco Locatelli,Loïc Dupré,Alberto Garaventa,Lorenzo Emmi,Marco Bregni,Graziella Cefalo,Antonia Moretta,Cesare Danesino,Margherita Comis,Andrea Pession,Ugo Ramenghi,Rita Maccario,Maurizio Aricò,Maria Grazia Roncarolo
NEOPLASIA
TEF, an antiapoptotic bZIP transcription factor related to the oncogenic E2A-HLF chimera, inhibits cell growth by down-regulating expression of the common β chain of cytokine receptors
Takeshi Inukai,Toshiya Inaba,Jinjun Dang,Ryoko Kuribara,Keiya Ozawa,Atsushi Miyajima,Wenshu Wu,A. Thomas Look,Yojiro Arinobu,Hiromi Iwasaki,Koichi Akashi,Keiko Kagami,Kumiko Goi,Kanji Sugita,Shinpei Nakazawa
Mantle-cell lymphoma genotypes identified with CGH to BAC microarrays define a leukemic subgroup of disease and predict patient outcome
Clinical Trials & Observations
Fanny Rubio-Moscardo,Joan Climent,Reiner Siebert,Miguel A. Piris,Jose I. Martín-Subero,Inga Nieländer,Javier Garcia-Conde,Martin J. S. Dyer,Maria Jose Terol,Daniel Pinkel,Jose A. Martinez-Climent
Azaspirane (N-N-diethyl-8,8-dipropyl-2-azaspiro [4.5] decane-2-propanamine) inhibits human multiple myeloma cell growth in the bone marrow milieu in vitro and in vivo
Makoto Hamasaki,Teru Hideshima,Pierfrancesco Tassone,Paola Neri,Kenji Ishitsuka,Hiroshi Yasui,Norihiko Shiraishi,Noopur Raje,Shaji Kumar,Donald H. Picker,Gary S. Jacob,Paul G. Richardson,Nikhil C. Munshi,Kenneth C. Anderson
A novel CDK inhibitor, CYC202 (R-roscovitine), overcomes the defect in p53-dependent apoptosis in B-CLL by down-regulation of genes involved in transcription regulation and survival
Azra J. Alvi,Belinda Austen,Victoria J. Weston,Christopher Fegan,David MacCallum,Athos Gianella-Borradori,David P. Lane,Mike Hubank,Judith E. Powell,Wenbin Wei,A. Malcolm R. Taylor,Paul A. H. Moss,Tatjana Stankovic
Constitutive mobilization of CD34+ cells into the peripheral blood in idiopathic myelofibrosis may be due to the action of a number of proteases
Mingjiang Xu,Edward Bruno,Joseph Chao,Stephen Huang,Guido Finazzi,Steven M. Fruchtman,Uday Popat,Josef T. Prchal,Giovanni Barosi,Ronald Hoffman,for the MPD Research Consortium
AML1-FOG2 fusion protein in myelodysplasia
Brief Report
Edward M. Chan,Elisha M. Comer,Frank C. Brown,Kathleen E. Richkind,Melissa L. Holmes,Beng H. Chong,Roger Shiffman,Dong-Er Zhang,Marilyn L. Slovak,Cheryl L. Willman,Constance T. Noguchi,Yanjun Li,Devan J. Heiber,Lori Kwan,Rebecca J. Chan,Gail H. Vance,Heather C. Ramsey,Robert A. Hromas
RED CELLS
TRANSPLANTATION
Outcomes for reduced-intensity allogeneic transplantation for multiple myeloma: an analysis of prognostic factors from the Chronic Leukaemia Working Party of the EBMT
Clinical Trials & Observations
Charles Crawley,Marc Lalancette,Richard Szydlo,Maria Gilleece,Karl Peggs,Stephen Mackinnon,Gunnar Juliusson,Lucia Ahlberg,Arnon Nagler,Avichai Shimoni,Anna Sureda,Jean-Michel Boiron,Herman Einsele,Rajesh Chopra,Angelo Carella,Jamie Cavenagh,Alois Gratwohl,Frederic Garban,Axel Zander,Bo Björkstrand,Dietger Niederwieser,Gösta Gahrton,Jane F. Apperley,for the Chronic Leukaemia Working Party of the EBMT
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