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Volume 104, Issue 7

October 1 2004

In this Issue

INSIDE BLOOD
BLOOD WORK
PLENARY PAPERS
REVIEW ARTICLES
REVIEW IN TRANSLATIONAL HEMATOLOGY
CHEMOKINES
CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS
HEMATOPOIESIS
HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY
IMMUNOBIOLOGY
NEOPLASIA
RED CELLS
TRANSPLANTATION
CORRESPONDENCE

INSIDE BLOOD

HEMOSTASIS

Are oncogenes responsible for hemophilic arthropathy?

Thomas Abshire

View Articletitled, Are oncogenes responsible for hemophilic arthropathy?

IMMUNOBIOLOGY

HLA-C alleles can no longer be ignored in bone marrow donor selection

Jon J. van Rood

View Articletitled, HLA-C alleles can no longer be ignored in bone marrow donor selection

CLINICAL OBSERVATIONS

Acute promyelocytic leukemia: a target for preemptive strike?

Dan Douer

View Articletitled, Acute promyelocytic leukemia: a target for preemptive strike?

HEMATOPOIESIS

Stuck on the TRAIL of osteoclast differentiation

Elizabeth Olmsted Davis

View Articletitled, Stuck on the TRAIL of osteoclast differentiation

CHEMOKINES

The APC's of tumor vaccine therapy

Scott S. Zamvil,Thomas Prod'homme

View Articletitled, The APC's of tumor vaccine therapy

IMMUNOBIOLOGY

Players in the sandbox of childhood ITP

Gowthami Arepally

View Articletitled, Players in the sandbox of childhood ITP

NEOPLASIA

Restraining CML by adhesives

Ruibao Ren

View Articletitled, Restraining CML by adhesives

RED CELLS

Hemojuvelin and hepcidin: the keys to JH?

Eric Nisbet-Brown

View Articletitled, Hemojuvelin and hepcidin: the keys to JH?

NEOPLASIA

Site-specific conversion of a pro-fusion protein toxin

John R. Murphy

View Articletitled, Site-specific conversion of a pro-fusion protein toxin

TRANSPLANTATION

Immunoregulation in human bone marrow transplantation?

Matthias Edinger

View Articletitled, Immunoregulation in human bone marrow transplantation?

BLOOD WORK

Essential thrombocythemia

View Articletitled, Essential thrombocythemia

PLENARY PAPERS

Impact of HLA class I and class II high-resolution matching on outcomes of unrelated donor bone marrow transplantation: HLA-C mismatching is associated with a strong adverse effect on transplantation outcome
Clinical Trials & Observations

Neal Flomenberg,Lee Ann Baxter-Lowe,Dennis Confer,Marcelo Fernandez-Vina,Alexandra Filipovich,Mary Horowitz,Carolyn Hurley,Craig Kollman,Claudio Anasetti,Harriet Noreen,Ann Begovich,William Hildebrand,Effie Petersdorf,Barbara Schmeckpeper,Michelle Setterholm,Elizabeth Trachtenberg,Thomas Williams,Edmond Yunis,Daniel Weisdorf

View Articletitled, Impact of HLA class I and class II high-resolution matching on outcomes of unrelated donor bone marrow transplantation: HLA-C mismatching is associated with a strong adverse effect on transplantation outcome

REVIEW ARTICLES

Imatinib targets other than bcr/abl and their clinical relevance in myeloid disorders

Animesh Pardanani,Ayalew Tefferi

View Articletitled, Imatinib targets other than bcr/abl and their clinical relevance in myeloid disorders

REVIEW IN TRANSLATIONAL HEMATOLOGY

Targeting the multidrug resistance-1 transporter in AML: molecular regulation and therapeutic strategies
Clinical Trials & Observations

Daruka Mahadevan,Alan F. List

View Articletitled, Targeting the multidrug resistance-1 transporter in AML: molecular regulation and therapeutic strategies

CHEMOKINES

Unique gene expression program of human germinal center T helper cells

Chang H. Kim,Hyung W. Lim,Jong R. Kim,Lusijah Rott,Peter Hillsamer,Eugene C. Butcher

View Articletitled, Unique gene expression program of human germinal center T helper cells

Supplemental data

Chemokine receptor-mediated delivery directs self-tumor antigen efficiently into the class II processing pathway in vitro and induces protective immunity in vivo

Arya Biragyn,Pier Adelchi Ruffini,Marta Coscia,Linda K. Harvey,Sattva S. Neelapu,Sivasubramanian Baskar,Ji-Ming Wang,Larry W. Kwak

View Articletitled, Chemokine receptor-mediated delivery directs self-tumor antigen efficiently into the class II processing pathway in vitro and induces protective immunity in vivo

CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS

Quiescent phenotype of tumor-specific CD8⁺ T cells following immunization
Clinical Trials & Observations

Vladia Monsurrò,Ena Wang,Yoshisha Yamano,Stephen A. Migueles,Monica C. Panelli,Kina Smith,Dirk Nagorsen,Mark Connors,Steven Jacobson,Francesco M. Marincola

View Articletitled, Quiescent phenotype of tumor-specific CD8+ T cells following immunization

Long-term survival benefit and improved complete cytogenetic and molecular response rates with imatinib mesylate in Philadelphia chromosome–positive chronic-phase chronic myeloid leukemia after failure of interferon-α
Clinical Trials & Observations

Hagop M. Kantarjian,Jorge E. Cortes,Susan O'Brien,Rajyalakshmi Luthra,Francis Giles,Srdan Verstovsek,Stefan Faderl,Deborah Thomas,Guillermo Garcia-Manero,Mary Beth Rios,Jianqin Shan,Dan Jones,Moshe Talpaz

View Articletitled, Long-term survival benefit and improved complete cytogenetic and molecular response rates with imatinib mesylate in Philadelphia chromosome–positive chronic-phase chronic myeloid leukemia after failure of interferon-α

Responsiveness to G-CSF before leukopenia predicts defense to infection in high-dose chemotherapy recipients
Clinical Trials & Observations

Christian Straka,Fuat Oduncu,Axel Hinke,Hermann Einsele,Evi Drexler,Brigitte Schnabel,Lubomir Arseniev,Jochem Walther,August König,Bertold Emmerich

View Articletitled, Responsiveness to G-CSF before leukopenia predicts defense to infection in high-dose chemotherapy recipients

Gemtuzumab ozogamicin (Mylotarg) as a single agent for molecularly relapsed acute promyelocytic leukemia
Clinical Trials & Observations

Francesco Lo-Coco,Giuseppe Cimino,Massimo Breccia,Nélida I. Noguera,Daniela Diverio,Erica Finolezzi,Enrico M. Pogliani,Eros Di Bona,Concetta Micalizzi,Mariagrazia Kropp,Adriano Venditti,Agostino Tafuri,Franco Mandelli

View Articletitled, Gemtuzumab ozogamicin (Mylotarg) as a single agent for molecularly relapsed acute promyelocytic leukemia

Experimental assessment of disinfection procedures for eradication of Aspergillus fumigatus in food
Clinical Trials & Observations Brief Report

Jean-Pierre Gangneux,Latifa Noussair,Adel Bouakline,Nicole Roux,Claire Lacroix,Francis Derouin

View Articletitled, Experimental assessment of disinfection procedures for eradication of Aspergillus fumigatus in food

α⁺-thalassemia protects African children from severe malaria
Clinical Trials & Observations Brief Report

Frank P. Mockenhaupt,Stephan Ehrhardt,Sabine Gellert,Rowland N. Otchwemah,Ekkehart Dietz,Sylvester D. Anemana,Ulrich Bienzle

View Articletitled, α+-thalassemia protects African children from severe malaria

Unusual immunophenotype of CD8⁺ T cells in familial hemophagocytic lymphohistiocytosis
Clinical Trials & Observations Brief Report

Nitin J. Karandikar,Steven H. Kroft,Subramanian Yegappan,Beverly B. Rogers,Victor M. Aquino,Kyung-Mi Lee,Vinay Kumar,F. Javier Guenaga,Elaine S. Jaffe,Daniel C. Douek,Robert W. McKenna

View Articletitled, Unusual immunophenotype of CD8+ T cells in familial hemophagocytic lymphohistiocytosis

HEMATOPOIESIS

The role of angiopoietins in the development of endothelial cells from cord blood CD34⁺ progenitors

Patrick Hildbrand,Vincenzo Cirulli,Robyn C. Prinsen,Kent A. Smith,Bruce E. Torbett,Daniel R. Salomon,Laura Crisa

View Articletitled, The role of angiopoietins in the development of endothelial cells from cord blood CD34+ progenitors

Supplemental data

Integrin α₄β₇ and its counterreceptor MAdCAM-1 contribute to hematopoietic progenitor recruitment into bone marrow following transplantation

Yoshio Katayama,Andrés Hidalgo,Anna Peired,Paul S. Frenette

View Articletitled, Integrin α4β7 and its counterreceptor MAdCAM-1 contribute to hematopoietic progenitor recruitment into bone marrow following transplantation

Upstream stimulatory factors stimulate transcription through E-box motifs in the PF4 gene in megakaryocytes

Yoshiaki Okada,Eri Matsuura,Zenzaburo Tozuka,Ryohei Nagai,Ayako Watanabe,Kayoko Matsumoto,Kazuta Yasui,Robert W. Jackman,Toru Nakano,Takefumi Doi

View Articletitled, Upstream stimulatory factors stimulate transcription through E-box motifs in the PF4 gene in megakaryocytes

Translocation of the inhibitor of apoptosis protein c-IAP1 from the nucleus to the Golgi in hematopoietic cells undergoing differentiation: a nuclear export signal-mediated event

Stéphanie Plenchette,Séverine Cathelin,Cédric Rébé,Sophie Launay,Sylvain Ladoire,Olivier Sordet,Tibor Ponnelle,Najet Debili,Thi-Hai Phan,Rose-Ann Padua,Laurence Dubrez-Daloz,Eric Solary

View Articletitled, Translocation of the inhibitor of apoptosis protein c-IAP1 from the nucleus to the Golgi in hematopoietic cells undergoing differentiation: a nuclear export signal-mediated event

TNF-related apoptosis-inducing ligand (TRAIL) blocks osteoclastic differentiation induced by RANKL plus M-CSF

Giorgio Zauli,Erika Rimondi,Vanessa Nicolin,Elisabetta Melloni,Claudio Celeghini,Paola Secchiero

View Articletitled, TNF-related apoptosis-inducing ligand (TRAIL) blocks osteoclastic differentiation induced by RANKL plus M-CSF

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

Natural killer T cells accelerate atherogenesis in mice

Yukihito Nakai,Kazuya Iwabuchi,Satoshi Fujii,Naoki Ishimori,Nyambayar Dashtsoodol,Keiko Watano,Tetsuya Mishima,Chikako Iwabuchi,Shinya Tanaka,Jelena S. Bezbradica,Toshinori Nakayama,Masaru Taniguchi,Sachiko Miyake,Takashi Yamamura,Akira Kitabatake,Sebastian Joyce,Luc Van Kaer,Kazunori Onoé

View Articletitled, Natural killer T cells accelerate atherogenesis in mice

Pathobiology of hemophilic synovitis I: overexpression of mdm2 oncogene

Narine Hakobyan,Tamara Kazarian,Adnan A. Jabbar,Kausar J. Jabbar,Leonard A. Valentino

View Articletitled, Pathobiology of hemophilic synovitis I: overexpression of mdm2 oncogene

Inhibition of tumor angiogenesis in vivo by a monoclonal antibody targeted to domain 5 of high molecular weight kininogen

James S. Song,Irma M. Sainz,Stephen C. Cosenza,Irma Isordia-Salas,Abdel Bior,Harlan N. Bradford,Yan-Lin Guo,Robin A. Pixley,E. Premkumar Reddy,Robert W. Colman

View Articletitled, Inhibition of tumor angiogenesis in vivo by a monoclonal antibody targeted to domain 5 of high molecular weight kininogen

Erythropoietin and hypoxia stimulate erythropoietin receptor and nitric oxide production by endothelial cells

Bojana B. Beleslin-Cokic,Vladan P. Cokic,Xiaobing Yu,Babette B. Weksler,Alan N. Schechter,Constance Tom Noguchi

View Articletitled, Erythropoietin and hypoxia stimulate erythropoietin receptor and nitric oxide production by endothelial cells

Identification of novel mutations in ADAMTS13 in an adult patient with congenital thrombotic thrombocytopenic purpura
Clinical Trials & Observations Brief Report

Toshihiro Uchida,Hideo Wada,Minoru Mizutani,Miho Iwashita,Hiroaki Ishihara,Toshiro Shibano,Misako Suzuki,Yumiko Matsubara,Kenji Soejima,Masanori Matsumoto,Yoshihiro Fujimura,Yasuo Ikeda,Mitsuru Murata,for The Research Project on Genetics of Thrombosis

View Articletitled, Identification of novel mutations in ADAMTS13 in an adult patient with congenital thrombotic thrombocytopenic purpura

Adult bone marrow-derived cells recruited during angiogenesis comprise precursors for periendothelial vascular mural cells
Brief Report

Iiro Rajantie,Maritta Ilmonen,Agne Alminaite,Ugur Ozerdem,Kari Alitalo,Petri Salven

View Articletitled, Adult bone marrow-derived cells recruited during angiogenesis comprise precursors for periendothelial vascular mural cells

IMMUNOBIOLOGY

Killing of human immunodeficiency virus-infected primary T-cell blasts by autologous natural killer cells is dependent on the ability of the virus to alter the expression of major histocompatibility complex class I molecules

Matthew I. Bonaparte,Edward Barker

View Articletitled, Killing of human immunodeficiency virus-infected primary T-cell blasts by autologous natural killer cells is dependent on the ability of the virus to alter the expression of major histocompatibility complex class I molecules

A novel form of complete IL-12/IL-23 receptor β1 deficiency with cell surface-expressed nonfunctional receptors

Claire Fieschi,Marita Bosticardo,Ludovic de Beaucoudrey,Stéphanie Boisson-Dupuis,Jacqueline Feinberg,Orchidée Filipe Santos,Jacinta Bustamante,Jacov Levy,Fabio Candotti,Jean-Laurent Casanova

View Articletitled, A novel form of complete IL-12/IL-23 receptor β1 deficiency with cell surface-expressed nonfunctional receptors

Supplemental data

Exacerbation of autoantibody-mediated thrombocytopenic purpura by infection with mouse viruses

Andrei Musaji,Françoise Cormont,Gaëtan Thirion,César L. Cambiaso,Jean-Paul Coutelier

View Articletitled, Exacerbation of autoantibody-mediated thrombocytopenic purpura by infection with mouse viruses

Function and survival of dendritic cells depend on endothelin-1 and endothelin receptor autocrine loops

Georgi Guruli,Beth R. Pflug,Stefana Pecher,Valeria Makarenkova,Michael R. Shurin,Joel B. Nelson

View Articletitled, Function and survival of dendritic cells depend on endothelin-1 and endothelin receptor autocrine loops

Self-reactive memory-phenotype CD8 T cells exhibit both MHC-restricted and non-MHC-restricted cytotoxicity: a role for the T-cell receptor and natural killer cell receptors

Salim Dhanji,Soo-Jeet Teh,Darryl Oble,John J. Priatel,Hung-Sia Teh

View Articletitled, Self-reactive memory-phenotype CD8 T cells exhibit both MHC-restricted and non-MHC-restricted cytotoxicity: a role for the T-cell receptor and natural killer cell receptors

In a model of tumor dormancy, long-term persistent leukemic cells have increased B7-H1 and B7.1 expression and resist CTL-mediated lysis

Aurore Saudemont,Bruno Quesnel

View Articletitled, In a model of tumor dormancy, long-term persistent leukemic cells have increased B7-H1 and B7.1 expression and resist CTL-mediated lysis

NEOPLASIA

Clonotypic IgM V/D/J sequence analysis in Waldenstrom macroglobulinemia suggests an unusual B-cell origin and an expansion of polyclonal B cells in peripheral blood

Jitra Kriangkum,Brian J. Taylor,Steven P. Treon,Michael J. Mant,Andrew R. Belch,Linda M. Pilarski

View Articletitled, Clonotypic IgM V/D/J sequence analysis in Waldenstrom macroglobulinemia suggests an unusual B-cell origin and an expansion of polyclonal B cells in peripheral blood

A urokinase-activated recombinant diphtheria toxin targeting the granulocyte-macrophage colony-stimulating factor receptor is selectively cytotoxic to human acute myeloid leukemia blasts

Ralph J. Abi-Habib,Shihui Liu,Thomas H. Bugge,Stephen H. Leppla,Arthur E. Frankel

View Articletitled, A urokinase-activated recombinant diphtheria toxin targeting the granulocyte-macrophage colony-stimulating factor receptor is selectively cytotoxic to human acute myeloid leukemia blasts

Anti-α4 integrin antibody suppresses the development of multiple myeloma and associated osteoclastic osteolysis

Yoshihisa Mori,Nobuaki Shimizu,Mark Dallas,Maryla Niewolna,Beryl Story,Paul J. Williams,Gregory R. Mundy,Toshiyuki Yoneda

View Articletitled, Anti-α4 integrin antibody suppresses the development of multiple myeloma and associated osteoclastic osteolysis

Polymorphisms and haplotypes in folate-metabolizing genes and risk of non-Hodgkin lymphoma

Christine F. Skibola,Matthew S. Forrest,Fabio Coppedé,Luz Agana,Alan Hubbard,Martyn T. Smith,Paige M. Bracci,Elizabeth A. Holly

View Articletitled, Polymorphisms and haplotypes in folate-metabolizing genes and risk of non-Hodgkin lymphoma

Lack of the adhesion molecules P-selectin and intercellular adhesion molecule-1 accelerate the development of BCR/ABL-induced chronic myeloid leukemia-like myeloproliferative disease in mice

Shawn D. Pelletier,Daniel S. Hong,Yiguo Hu,Yuhua Liu,Shaoguang Li

View Articletitled, Lack of the adhesion molecules P-selectin and intercellular adhesion molecule-1 accelerate the development of BCR/ABL-induced chronic myeloid leukemia-like myeloproliferative disease in mice

Multiple myeloma cells catalyze hepatocyte growth factor (HGF) activation by secreting the serine protease HGF-activator
Brief Report

Esther P.M. Tjin,Patrick W.B. Derksen,Hiroaki Kataoka,Marcel Spaargaren,Steven T. Pals

View Articletitled, Multiple myeloma cells catalyze hepatocyte growth factor (HGF) activation by secreting the serine protease HGF-activator

RED CELLS

Identification of a novel mutation (C321X) in HJV
Clinical Trials & Observations Brief Report

Franklin W. Huang,Isabel Rubio-Aliaga,James P. Kushner,Nancy C. Andrews,Mark D. Fleming

View Articletitled, Identification of a novel mutation (C321X) in HJV

Inhibition of iron transport across human intestinal epithelial cells by hepcidin
Brief Report

Sachie Yamaji,Paul Sharp,Bala Ramesh,Surjit Kaila Srai

View Articletitled, Inhibition of iron transport across human intestinal epithelial cells by hepcidin

Severe hemochromatosis in a Portuguese family associated with a new mutation in the 5′-UTR of the HAMP gene
Clinical Trials & Observations

Thomas Matthes,Patricia Aguilar-Martinez,Loredana Pizzi-Bosman,Régis Darbellay,Laura Rubbia-Brandt,Emilio Giostra,Martine Michel,Tomas Ganz,Photis Beris

View Articletitled, Severe hemochromatosis in a Portuguese family associated with a new mutation in the 5′-UTR of the HAMP gene

Quantitative trait locus on chromosome 8q influences the switch from fetal to adult hemoglobin
Brief Report

Chad Garner,Nicholas Silver,Steve Best,Stephan Menzel,Charlotte Martin,Tim D. Spector,Swee Lay Thein

View Articletitled, Quantitative trait locus on chromosome 8q influences the switch from fetal to adult hemoglobin

TRANSPLANTATION

Association of Foxp3 regulatory gene expression with graft-versus-host disease

Yuji Miura,Christopher J. Thoburn,Emilie C. Bright,Michele L. Phelps,Tahiro Shin,Elizabeth C. Matsui,William H. Matsui,Sally Arai,Ephraim J. Fuchs,Georgia B. Vogelsang,Richard J. Jones,Allan D. Hess

View Articletitled, Association of Foxp3 regulatory gene expression with graft-versus-host disease

Physicians' attitudes about quality-of-life issues in hematopoietic stem cell transplantation
Clinical Trials & Observations

Stephanie J. Lee,Steven Joffe,Haesook T. Kim,Gerard Socie,Andrew L. Gilman,John R. Wingard,Mary M. Horowitz,David Cella,Karen L. Syrjala

View Articletitled, Physicians' attitudes about quality-of-life issues in hematopoietic stem cell transplantation

CORRESPONDENCE

Comparison of rHuEpo plus rHuG-CSF and supportive care: apples to oranges

Roberto Stasi,Sergio Amadori,Adrian C. Newland,Drew Provan

View Articletitled, Comparison of rHuEpo plus rHuG-CSF and supportive care: apples to oranges

Engraftment of distinct clonal MDS-derived hematopoietic precursors in NOD/SCID-β2-microglobulin-deficient mice after intramedullary transplantation of hematopoietic and stromal cells

Daniella M. Bahia Kerbauy,Vladimir Lesnikov,Beverly Torok-Storb,Eileen Bryant,H. Joachim Deeg

View Articletitled, Engraftment of distinct clonal MDS-derived hematopoietic precursors in NOD/SCID-β2-microglobulin-deficient mice after intramedullary transplantation of hematopoietic and stromal cells

Discontinuation of imatinib therapy after achieving a molecular response

Jorge Cortes,Susan O'Brien,Hagop Kantarjian

View Articletitled, Discontinuation of imatinib therapy after achieving a molecular response

CCR5-specific mucosal IgA in saliva and genital fluids of HIV-exposed seronegative subjects

Claudia Barassi,Adriano Lazzarin,Lucia Lopalco

View Articletitled, CCR5-specific mucosal IgA in saliva and genital fluids of HIV-exposed seronegative subjects

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Novel biomarker-based probability engine

Help on the way to unsilence HbF

Improved survival in cHL with novel agents

Targeted therapy in mediastinal gray zone lymphoma

Kemps PG, Picarsic J, Durham BH, et al. ALK-positive histiocytosis: a new clinicopathologic spectrum highlighting neurologic involvement and responses to ALK inhibition. Blood. 2022;139(2):256-280.

Issue Archive

Table of Contents

INSIDE BLOOD

BLOOD WORK

PLENARY PAPERS

Impact of HLA class I and class II high-resolution matching on outcomes of unrelated donor bone marrow transplantation: HLA-C mismatching is associated with a strong adverse effect on transplantation outcome Clinical Trials & Observations

REVIEW ARTICLES

REVIEW IN TRANSLATIONAL HEMATOLOGY

Targeting the multidrug resistance-1 transporter in AML: molecular regulation and therapeutic strategies Clinical Trials & Observations

CHEMOKINES

CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS

Quiescent phenotype of tumor-specific CD8+ T cells following immunization Clinical Trials & Observations

Long-term survival benefit and improved complete cytogenetic and molecular response rates with imatinib mesylate in Philadelphia chromosome–positive chronic-phase chronic myeloid leukemia after failure of interferon-α Clinical Trials & Observations

Responsiveness to G-CSF before leukopenia predicts defense to infection in high-dose chemotherapy recipients Clinical Trials & Observations

Gemtuzumab ozogamicin (Mylotarg) as a single agent for molecularly relapsed acute promyelocytic leukemia Clinical Trials & Observations

Experimental assessment of disinfection procedures for eradication of Aspergillus fumigatus in food Clinical Trials & Observations Brief Report

α+-thalassemia protects African children from severe malaria Clinical Trials & Observations Brief Report

Unusual immunophenotype of CD8+ T cells in familial hemophagocytic lymphohistiocytosis Clinical Trials & Observations Brief Report

HEMATOPOIESIS

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

Identification of novel mutations in ADAMTS13 in an adult patient with congenital thrombotic thrombocytopenic purpura Clinical Trials & Observations Brief Report

Adult bone marrow-derived cells recruited during angiogenesis comprise precursors for periendothelial vascular mural cells Brief Report

IMMUNOBIOLOGY

NEOPLASIA

Multiple myeloma cells catalyze hepatocyte growth factor (HGF) activation by secreting the serine protease HGF-activator Brief Report

RED CELLS

Identification of a novel mutation (C321X) in HJV Clinical Trials & Observations Brief Report

Inhibition of iron transport across human intestinal epithelial cells by hepcidin Brief Report

Severe hemochromatosis in a Portuguese family associated with a new mutation in the 5′-UTR of the HAMP gene Clinical Trials & Observations

Quantitative trait locus on chromosome 8q influences the switch from fetal to adult hemoglobin Brief Report

TRANSPLANTATION

Physicians' attitudes about quality-of-life issues in hematopoietic stem cell transplantation Clinical Trials & Observations

CORRESPONDENCE

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American Society of Hematology

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Impact of HLA class I and class II high-resolution matching on outcomes of unrelated donor bone marrow transplantation: HLA-C mismatching is associated with a strong adverse effect on transplantation outcome
Clinical Trials & Observations

Targeting the multidrug resistance-1 transporter in AML: molecular regulation and therapeutic strategies
Clinical Trials & Observations

Quiescent phenotype of tumor-specific CD8⁺ T cells following immunization
Clinical Trials & Observations

Long-term survival benefit and improved complete cytogenetic and molecular response rates with imatinib mesylate in Philadelphia chromosome–positive chronic-phase chronic myeloid leukemia after failure of interferon-α
Clinical Trials & Observations

Responsiveness to G-CSF before leukopenia predicts defense to infection in high-dose chemotherapy recipients
Clinical Trials & Observations

Gemtuzumab ozogamicin (Mylotarg) as a single agent for molecularly relapsed acute promyelocytic leukemia
Clinical Trials & Observations

Experimental assessment of disinfection procedures for eradication of Aspergillus fumigatus in food
Clinical Trials & Observations Brief Report

α⁺-thalassemia protects African children from severe malaria
Clinical Trials & Observations Brief Report

Unusual immunophenotype of CD8⁺ T cells in familial hemophagocytic lymphohistiocytosis
Clinical Trials & Observations Brief Report

Identification of novel mutations in ADAMTS13 in an adult patient with congenital thrombotic thrombocytopenic purpura
Clinical Trials & Observations Brief Report

Adult bone marrow-derived cells recruited during angiogenesis comprise precursors for periendothelial vascular mural cells
Brief Report

Multiple myeloma cells catalyze hepatocyte growth factor (HGF) activation by secreting the serine protease HGF-activator
Brief Report

Identification of a novel mutation (C321X) in HJV
Clinical Trials & Observations Brief Report

Inhibition of iron transport across human intestinal epithelial cells by hepcidin
Brief Report

Severe hemochromatosis in a Portuguese family associated with a new mutation in the 5′-UTR of the HAMP gene
Clinical Trials & Observations

Quantitative trait locus on chromosome 8q influences the switch from fetal to adult hemoglobin
Brief Report

Physicians' attitudes about quality-of-life issues in hematopoietic stem cell transplantation
Clinical Trials & Observations