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INSIDE BLOOD

Homer goes nucleus

Patrick Matthias

View Articletitled, Homer goes nucleus

Responsiveness of patients with VWD to DDAVP

Robert R. Montgomery

View Articletitled, Responsiveness of patients with VWD to DDAVP

Can increased cytokine receptor signaling cause leukemia?

Kenneth Weinberg

View Articletitled, Can increased cytokine receptor signaling cause leukemia?

Fibrinogen contributions to arterial thrombus formation: vessel size counts

Michael W. Mosesson

View Articletitled, Fibrinogen contributions to arterial thrombus formation: vessel size counts

JAK3: not just another kinase

Wilhelm Friedrich

View Articletitled, JAK3: not just another kinase

Propelling the platelet proteome

Andrew S. Weyrich,Guy A. Zimmerman

View Articletitled, Propelling the platelet proteome

P-selectin and VWF tie the knot

Paul S. Frenette

View Articletitled, P-selectin and VWF tie the knot

Integrins, mast cells, and innate immunity

Eric J. Brown

View Articletitled, Integrins, mast cells, and innate immunity

T cells in mouse follicular lymphoma

Michael A. Teitell

View Articletitled, T cells in mouse follicular lymphoma

Mutated SHP and AML in leukemias

Gen-Sheng Feng

View Articletitled, Mutated SHP and AML in leukemias

PLENARY PAPERS

Overexpression of IL-7Rα provides a competitive advantage during early T-cell development

Yasmina Laouar,I. Nicholas Crispe,Richard A. Flavell

View Articletitled, Overexpression of IL-7Rα provides a competitive advantage during early T-cell development

Antibody blockade or mutation of the fibrinogen γ-chain C-terminus is more effective in inhibiting murine arterial thrombus formation than complete absence of fibrinogen

Markéta Jiroušková,Igor Chereshnev,Heikki Väänänen,Jay L. Degen,Barry S. Coller

View Articletitled, Antibody blockade or mutation of the fibrinogen γ-chain C-terminus is more effective in inhibiting murine arterial thrombus formation than complete absence of fibrinogen

Supplemental data

PERSPECTIVES

The impact of cytomegalovirus serostatus of donor and recipient before hematopoietic stem cell transplantation in the era of antiviral prophylaxis and preemptive therapy
Clinical Trials & Observations

Michael Boeckh,W. Garrett Nichols

View Articletitled, The impact of cytomegalovirus serostatus of donor and recipient before hematopoietic stem cell transplantation in the era of antiviral prophylaxis and preemptive therapy

CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS

Janus kinase 3 (JAK3) deficiency: clinical, immunologic, and molecular analyses of 10 patients and outcomes of stem cell transplantation
Clinical Trials & Observations

Joseph L. Roberts,Andrea Lengi,Stephanie M. Brown,Min Chen,Yong-Jie Zhou,John J. O'Shea,Rebecca H. Buckley

View Articletitled, Janus kinase 3 (JAK3) deficiency: clinical, immunologic, and molecular analyses of 10 patients and outcomes of stem cell transplantation

Acquired somatic ATRX mutations in myelodysplastic syndrome associated with α thalassemia (ATMDS) convey a more severe hematologic phenotype than germline ATRX mutations
Clinical Trials & Observations

David P. Steensma,Douglas R. Higgs,Chris A. Fisher,Richard J. Gibbons

View Articletitled, Acquired somatic ATRX mutations in myelodysplastic syndrome associated with α thalassemia (ATMDS) convey a more severe hematologic phenotype than germline ATRX mutations

Early prediction of outcome and response to alemtuzumab therapy in chronic lymphocytic leukemia
Clinical Trials & Observations

Andy C. Rawstron,Ben Kennedy,Paul Moreton,Anita J. Dickinson,Matthew J. Cullen,Stephen J. Richards,Andrew S. Jack,Peter Hillmen

View Articletitled, Early prediction of outcome and response to alemtuzumab therapy in chronic lymphocytic leukemia

Biologic response to desmopressin in patients with severe type 1 and type 2 von Willebrand disease: results of a multicenter European study
Clinical Trials & Observations

Augusto B. Federici,Claudine Mazurier,Erik Berntorp,Christine A. Lee,Inge Scharrer,Jenny Goudemand,Stephan Lethagen,Ioana Nitu,Gerard Ludwig,Lysiane Hilbert,Pier M. Mannucci

View Articletitled, Biologic response to desmopressin in patients with severe type 1 and type 2 von Willebrand disease: results of a multicenter European study

Sustained long-term hematologic efficacy of hydroxyurea at maximum tolerated dose in children with sickle cell disease
Clinical Trials & Observations

Sherri A. Zimmerman,William H. Schultz,Jacqueline S. Davis,Chrisley V. Pickens,Nicole A. Mortier,Thad A. Howard,Russell E. Ware

View Articletitled, Sustained long-term hematologic efficacy of hydroxyurea at maximum tolerated dose in children with sickle cell disease

GENE THERAPY

RNA-transfected CD40-activated B cells induce functional T-cell responses against viral and tumor antigen targets: implications for pediatric immunotherapy

Christina M. Coughlin,Barbara A. Vance,Stephan A. Grupp,Robert H. Vonderheide

View Articletitled, RNA-transfected CD40-activated B cells induce functional T-cell responses against viral and tumor antigen targets: implications for pediatric immunotherapy

HEMATOPOIESIS

Alternative promoters regulate transcription of the gene that encodes stem cell surface protein AC133

Sergey V. Shmelkov,Lin Jun,Ryan St Clair,Deirdre McGarrigle,Christopher A. Derderian,Jaroslav K. Usenko,Carla Costa,Fan Zhang,Xinzheng Guo,Shahin Rafii

View Articletitled, Alternative promoters regulate transcription of the gene that encodes stem cell surface protein AC133

Early hematopoietic zinc finger protein (EHZF), the human homolog to mouse Evi3, is highly expressed in primitive human hematopoietic cells

Heather M. Bond,Maria Mesuraca,Ennio Carbone,Patrizia Bonelli,Valter Agosti,Nicola Amodio,Gennaro De Rosa,Massimo Di Nicola,Alessandro M. Gianni,Malcolm A. S. Moore,Akiko Hata,Michele Grieco,Giovanni Morrone,Salvatore Venuta

View Articletitled, Early hematopoietic zinc finger protein (EHZF), the human homolog to mouse Evi3, is highly expressed in primitive human hematopoietic cells

Mobilization studies in mice deficient in either C3 or C3a receptor (C3aR) reveal a novel role for complement in retention of hematopoietic stem/progenitor cells in bone marrow

Janina Ratajczak,Ryan Reca,Magda Kucia,Marcin Majka,Daniel J. Allendorf,Jarek T. Baran,Anna Janowska-Wieczorek,Rick A. Wetsel,Gordon D. Ross,Mariusz Z. Ratajczak

View Articletitled, Mobilization studies in mice deficient in either C3 or C3a receptor (C3aR) reveal a novel role for complement in retention of hematopoietic stem/progenitor cells in bone marrow

Impaired bone marrow homing of cytokine-activated CD34⁺ cells in the NOD/SCID model

Forhad Ahmed,Stuart J. Ings,Arnold R. Pizzey,Michael P. Blundell,Adrian J. Thrasher,Hong T. Ye,Anne Fahey,David C. Linch,Kwee L. Yong

View Articletitled, Impaired bone marrow homing of cytokine-activated CD34+ cells in the NOD/SCID model

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

Differential proteome analysis of TRAP-activated platelets: involvement of DOK-2 and phosphorylation of RGS proteins

Angel García,Sripadi Prabhakar,Sascha Hughan,Tom W. Anderson,Chris J. Brock,Andrew C. Pearce,Raymond A. Dwek,Steve P. Watson,Holger F. Hebestreit,Nicole Zitzmann

View Articletitled, Differential proteome analysis of TRAP-activated platelets: involvement of DOK-2 and phosphorylation of RGS proteins

Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions

Judith A. Coppinger,Gerard Cagney,Sinead Toomey,Thomas Kislinger,Orina Belton,James P. McRedmond,Dolores J. Cahill,Andrew Emili,Desmond J. Fitzgerald,Patricia B. Maguire

View Articletitled, Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions

Supplemental data

Aggretin, a snake venom–derived endothelial integrin α₂β₁ agonist, induces angiogenesis via expression of vascular endothelial growth factor

Ching-Hu Chung,Wen-Bin Wu,Tur-Fu Huang

View Articletitled, Aggretin, a snake venom–derived endothelial integrin α2β1 agonist, induces angiogenesis via expression of vascular endothelial growth factor

Identification of a binding site on human FGF-2 for fibrinogen

Hu Peng,Abha Sahni,Philip Fay,Stephen Bellum,Igor Prudovsky,Thomas Maciag,Charles W. Francis

View Articletitled, Identification of a binding site on human FGF-2 for fibrinogen

Antibodies to tissue-type plasminogen activator (tPA) in patients with antiphospholipid syndrome: evidence of interaction between the antibodies and the catalytic domain of tPA in 2 patients

Massimo Cugno,Mara Cabibbe,Monica Galli,Pier Luigi Meroni,Sonia Caccia,Rosaria Russo,Bianca Bottasso,Pier Mannuccio Mannucci

View Articletitled, Antibodies to tissue-type plasminogen activator (tPA) in patients with antiphospholipid syndrome: evidence of interaction between the antibodies and the catalytic domain of tPA in 2 patients

Initial accumulation of platelets during arterial thrombus formation in vivo is inhibited by elevation of basal cAMP levels

Derek S. Sim,Glenn Merrill-Skoloff,Barbara C. Furie,Bruce Furie,Robert Flaumenhaft

View Articletitled, Initial accumulation of platelets during arterial thrombus formation in vivo is inhibited by elevation of basal cAMP levels

Supplemental data

Role of p300 and PCAF in regulating cyclooxygenase-2 promoter activation by inflammatory mediators

Wu-Guo Deng,Ying Zhu,Kenneth K. Wu

View Articletitled, Role of p300 and PCAF in regulating cyclooxygenase-2 promoter activation by inflammatory mediators

Interactions of Aspergillus fumigatus with endothelial cells: internalization, injury, and stimulation of tissue factor activity

Leila M. Lopes Bezerra,Scott G. Filler

View Articletitled, Interactions of Aspergillus fumigatus with endothelial cells: internalization, injury, and stimulation of tissue factor activity

P-selectin anchors newly released ultralarge von Willebrand factor multimers to the endothelial cell surface

Arnoldo Padilla,Joel L. Moake,Aubrey Bernardo,Chalmette Ball,Yongtao Wang,Maneesh Arya,Leticia Nolasco,Nancy Turner,Michael C. Berndt,Bahman Anvari,José A. López,Jing-Fei Dong

View Articletitled, P-selectin anchors newly released ultralarge von Willebrand factor multimers to the endothelial cell surface

Hyperprothrombinemia associated with prothrombin G20210A mutation inhibits plasma fibrinolysis through a TAFI-mediated mechanism
Clinical Trials & Observations

Mario Colucci,Bianca M. Binetti,Armando Tripodi,Veena Chantarangkul,Nicola Semeraro

View Articletitled, Hyperprothrombinemia associated with prothrombin G20210A mutation inhibits plasma fibrinolysis through a TAFI-mediated mechanism

IMMUNOBIOLOGY

CpG-A and CpG-B oligonucleotides differentially enhance human peptide–specific primary and memory CD8⁺ T-cell responses in vitro

Simon Rothenfusser,Veit Hornung,Maha Ayyoub,Stefanie Britsch,Andreas Towarowski,Anne Krug,Anja Sarris,Norbert Lubenow,Daniel Speiser,Stefan Endres,Gunther Hartmann

View Articletitled, CpG-A and CpG-B oligonucleotides differentially enhance human peptide–specific primary and memory CD8+ T-cell responses in vitro

Immunodeficiency virus uptake, turnover, and 2-phase transfer in human dendritic cells

Stuart G. Turville,John J. Santos,Ines Frank,Paul U. Cameron,John Wilkinson,Monica Miranda-Saksena,Joanne Dable,Hella Stössel,Nikolaus Romani,Michael Piatak, Jr,Jeffrey D. Lifson,Melissa Pope,Anthony L. Cunningham

View Articletitled, Immunodeficiency virus uptake, turnover, and 2-phase transfer in human dendritic cells

Mechanisms of hypergammaglobulinemia and impaired antigen-specific humoral immunity in HIV-1 infection

Angelo De Milito,Anna Nilsson,Kehmia Titanji,Rigmor Thorstensson,Elisabet Reizenstein,Mitsuo Narita,Sven Grutzmeier,Anders Sönnerborg,Francesca Chiodi

View Articletitled, Mechanisms of hypergammaglobulinemia and impaired antigen-specific humoral immunity in HIV-1 infection

Dendritic cells constitutively present self antigens in their immature state in vivo and regulate antigen presentation by controlling the rates of MHC class II synthesis and endocytosis

Nicholas S. Wilson,Dima El-Sukkari,José A. Villadangos

View Articletitled, Dendritic cells constitutively present self antigens in their immature state in vivo and regulate antigen presentation by controlling the rates of MHC class II synthesis and endocytosis

Activated protein C inhibits bronchial hyperresponsiveness and Th2 cytokine expression in mice

View Articletitled, Activated protein C inhibits bronchial hyperresponsiveness and Th2 cytokine expression in mice

Migration of Vδ1 and Vδ2 T cells in response to CXCR3 and CXCR4 ligands in healthy donors and HIV-1–infected patients: competition by HIV-1 Tat

Alessandro Poggi,Roberta Carosio,Daniela Fenoglio,Sabrina Brenci,Giuseppe Murdaca,Maurizio Setti,Francesco Indiveri,Silvia Scabini,Elisabetta Ferrero,Maria Raffaella Zocchi

View Articletitled, Migration of Vδ1 and Vδ2 T cells in response to CXCR3 and CXCR4 ligands in healthy donors and HIV-1–infected patients: competition by HIV-1 Tat

Mast cell–mediated inflammatory responses require the α2β1 integrin

Brian T. Edelson,Zhengzhi Li,Loretta K. Pappan,Mary M. Zutter

View Articletitled, Mast cell–mediated inflammatory responses require the α2β1 integrin

Supplemental data

ICSBP is critically involved in the normal development and trafficking of Langerhans cells and dermal dendritic cells

Giovanna Schiavoni,Fabrizio Mattei,Paola Borghi,Paola Sestili,Massimo Venditti,Herbert C. Morse, III,Filippo Belardelli,Lucia Gabriele

View Articletitled, ICSBP is critically involved in the normal development and trafficking of Langerhans cells and dermal dendritic cells

Distinct pathways of LPS-induced NF-κB activation and cytokine production in human myeloid and nonmyeloid cells defined by selective utilization of MyD88 and Mal/TIRAP

Evangelos Andreakos,Sandra M. Sacre,Clive Smith,Anna Lundberg,Serafim Kiriakidis,Tim Stonehouse,Claudia Monaco,Marc Feldmann,Brian M. Foxwell

View Articletitled, Distinct pathways of LPS-induced NF-κB activation and cytokine production in human myeloid and nonmyeloid cells defined by selective utilization of MyD88 and Mal/TIRAP

Identification of circulating antigen-specific CD4⁺ T lymphocytes with a CCR5⁺, cytotoxic phenotype in an HIV-1 long-term nonprogressor and in CMV infection

John J. Zaunders,Wayne B. Dyer,Bin Wang,Mee Ling Munier,Monica Miranda-Saksena,Rebecca Newton,John Moore,Charles R. Mackay,David A. Cooper,Nitin K. Saksena,Anthony D. Kelleher

View Articletitled, Identification of circulating antigen-specific CD4+ T lymphocytes with a CCR5+, cytotoxic phenotype in an HIV-1 long-term nonprogressor and in CMV infection

Homer-3 regulates activation of serum response element in T cells via its EVH1 domain

Kazuhiro Ishiguro,Ramnik Xavier

View Articletitled, Homer-3 regulates activation of serum response element in T cells via its EVH1 domain

BAFF/BLyS can potentiate B-cell selection with the B-cell coreceptor complex

Hidenori Hase,Yumiko Kanno,Masaru Kojima,Kaoru Hasegawa,Daisuke Sakurai,Hidefumi Kojima,Naoyuki Tsuchiya,Katsushi Tokunaga,Nobuhide Masawa,Miyuki Azuma,Ko Okumura,Tetsuji Kobata

View Articletitled, BAFF/BLyS can potentiate B-cell selection with the B-cell coreceptor complex

NEOPLASIA

Mutations in the tyrosine kinase domain of FLT3 define a new molecular mechanism of acquired drug resistance to PTK inhibitors in FLT3-ITD–transformed hematopoietic cells

Ksenia Bagrintseva,Ruth Schwab,Tobias M. Kohl,Susanne Schnittger,Sabine Eichenlaub,Joachim W. Ellwart,Wolfgang Hiddemann,Karsten Spiekermann

View Articletitled, Mutations in the tyrosine kinase domain of FLT3 define a new molecular mechanism of acquired drug resistance to PTK inhibitors in FLT3-ITD–transformed hematopoietic cells

VavP-Bcl2 transgenic mice develop follicular lymphoma preceded by germinal center hyperplasia

Alexander Egle,Alan W. Harris,Mary L. Bath,Lorraine O'Reilly,Suzanne Cory

View Articletitled, VavP-Bcl2 transgenic mice develop follicular lymphoma preceded by germinal center hyperplasia

Molecular response to imatinib in late chronic-phase chronic myeloid leukemia
Clinical Trials & Observations

View Articletitled, Molecular response to imatinib in late chronic-phase chronic myeloid leukemia

Receptor synergy of interleukin-6 (IL-6) and insulin-like growth factor-I in myeloma cells that highly express IL-6 receptor α

Saeid Abroun,Hideaki Ishikawa,Naohiro Tsuyama,Shangqin Liu,Fu-Jun Li,Ken-ichiro Otsuyama,Xu Zheng,Masanori Obata,Michio M. Kawano

View Articletitled, Receptor synergy of interleukin-6 (IL-6) and insulin-like growth factor-I in myeloma cells that highly express IL-6 receptor α

A novel mechanism for imatinib mesylate–induced cell death of BCR-ABL–positive human leukemic cells: caspase-independent, necrosis-like programmed cell death mediated by serine protease activity

Masayuki Okada,Souichi Adachi,Tsuyoshi Imai,Ken-ichiro Watanabe,Shin-ya Toyokuni,Masaki Ueno,Antonis S. Zervos,Guido Kroemer,Tatsutoshi Nakahata

View Articletitled, A novel mechanism for imatinib mesylate–induced cell death of BCR-ABL–positive human leukemic cells: caspase-independent, necrosis-like programmed cell death mediated by serine protease activity

IL-3 expression by myeloma cells increases both osteoclast formation and growth of myeloma cells

Jun Won Lee,Ho Yeon Chung,Lori A. Ehrlich,Diane F. Jelinek,Natalie S. Callander,G. David Roodman,Sun Jin Choi

View Articletitled, IL-3 expression by myeloma cells increases both osteoclast formation and growth of myeloma cells

High incidence of somatic mutations in the AML1/RUNX1 gene in myelodysplastic syndrome and low blast percentage myeloid leukemia with myelodysplasia

Hironori Harada,Yuka Harada,Hiromasa Niimi,Taiichi Kyo,Akiro Kimura,Toshiya Inaba

View Articletitled, High incidence of somatic mutations in the AML1/RUNX1 gene in myelodysplastic syndrome and low blast percentage myeloid leukemia with myelodysplasia

Mutations in PTPN11 implicate the SHP-2 phosphatase in leukemogenesis

Mignon L. Loh,Shashaank Vattikuti,Suzanne Schubbert,Melissa G. Reynolds,Elaine Carlson,Kenneth H. Lieuw,Jennifer W. Cheng,Connie M. Lee,David Stokoe,Jeannette M. Bonifas,Nicole P. Curtiss,Jason Gotlib,Soheil Meshinchi,Michelle M. Le Beau,Peter D. Emanuel,Kevin M. Shannon

View Articletitled, Mutations in PTPN11 implicate the SHP-2 phosphatase in leukemogenesis

Characterization of clonogenic multiple myeloma cells

William Matsui,Carol Ann Huff,Qiuju Wang,Matthew T. Malehorn,James Barber,Yvette Tanhehco,B. Douglas Smith,Curt I. Civin,Richard J. Jones

View Articletitled, Characterization of clonogenic multiple myeloma cells

Monoclonal CD5⁺ and CD5^- B-lymphocyte expansions are frequent in the peripheral blood of the elderly
Clinical Trials & Observations

Paolo Ghia,Giuseppina Prato,Cristina Scielzo,Stefania Stella,Massimo Geuna,Giuseppe Guida,Federico Caligaris-Cappio

View Articletitled, Monoclonal CD5+ and CD5- B-lymphocyte expansions are frequent in the peripheral blood of the elderly

Genetic control of myeloproliferation in BXH-2 mice

Karine Turcotte,Susan Gauthier,Loukia-Maria Mitsos,Chaim Shustik,Neal G. Copeland,Nancy A. Jenkins,Jean-Christophe Fournet,Paul Jolicoeur,Philippe Gros

View Articletitled, Genetic control of myeloproliferation in BXH-2 mice

Silencing of the p18^INK4c gene by promoter hypermethylation in Reed-Sternberg cells in Hodgkin lymphomas

Abel Sánchez-Aguilera,Julio Delgado,Francisca I. Camacho,Margarita Sánchez-Beato,Lydia Sánchez,Carlos Montalbán,Manuel F. Fresno,Carmen Martín,Miguel A. Piris,Juan F. García

View Articletitled, Silencing of the p18INK4c gene by promoter hypermethylation in Reed-Sternberg cells in Hodgkin lymphomas

Mutations of the PML tumor suppressor gene in acute promyelocytic leukemia
Brief Report

Carmela Gurrieri,Khedoudja Nafa,Taha Merghoub,Rosa Bernardi,Paola Capodieci,Andrea Biondi,Stephen Nimer,Dan Douer,Carlos Cordon-Cardo,Robert Gallagher,Pier Paolo Pandolfi

View Articletitled, Mutations of the PML tumor suppressor gene in acute promyelocytic leukemia

PHAGOCYTES

Ceramide inhibition of phospholipase D and its relationship to RhoA and ARF1 translocation in GTPγS-stimulated polymorphonuclear leukocytes

Pamela J. Mansfield,Shannon S. Carey,Vania Hinkovska-Galcheva,James A. Shayman,Laurence A. Boxer

View Articletitled, Ceramide inhibition of phospholipase D and its relationship to RhoA and ARF1 translocation in GTPγS-stimulated polymorphonuclear leukocytes

RED CELLS

Regulated secretion of glycosylated human ferritin from hepatocytes

Sharmistha Ghosh,Sarah Hevi,Steven L. Chuck

View Articletitled, Regulated secretion of glycosylated human ferritin from hepatocytes

Analysis of the biologic functions of H- and L-ferritins in HeLa cells by transfection with siRNAs and cDNAs: evidence for a proliferative role of L-ferritin

Anna Cozzi,Barbara Corsi,Sonia Levi,Paolo Santambrogio,Giorgio Biasiotto,Paolo Arosio

View Articletitled, Analysis of the biologic functions of H- and L-ferritins in HeLa cells by transfection with siRNAs and cDNAs: evidence for a proliferative role of L-ferritin

Expression of HbC and HbS, but not HbA, results in activation of K-Cl cotransport activity in transgenic mouse red cells

Jose R. Romero,Sandra M. Suzuka,Ronald L. Nagel,Mary E. Fabry

View Articletitled, Expression of HbC and HbS, but not HbA, results in activation of K-Cl cotransport activity in transgenic mouse red cells

Gene interactions and stroke risk in children with sickle cell anemia
Clinical Trials & Observations

Carolyn Hoppe,William Klitz,Suzanne Cheng,Ray Apple,Lori Steiner,Lara Robles,Tom Girard,Elliott Vichinsky,Lori Styles,the CSSCD Investigators

View Articletitled, Gene interactions and stroke risk in children with sickle cell anemia

Intravenous immune globulin prevents venular vaso-occlusion in sickle cell mice by inhibiting leukocyte adhesion and the interactions between sickle erythrocytes and adherent leukocytes
Brief Report

Aslihan Turhan,Pegah Jenab,Pierre Bruhns,Jeffrey V. Ravetch,Barry S. Coller,Paul S. Frenette

View Articletitled, Intravenous immune globulin prevents venular vaso-occlusion in sickle cell mice by inhibiting leukocyte adhesion and the interactions between sickle erythrocytes and adherent leukocytes

Supplemental data

Hemolytic anemia and severe rhabdomyolysis caused by compound heterozygous mutations of the gene for erythrocyte/muscle isozyme of aldolase, ALDOA^{(Arg303X/Cys338Tyr)}
Brief Report

David C. Yao,Dean R. Tolan,Michael F. Murray,David J. Harris,Basil T. Darras,Alon Geva,Ellis J. Neufeld

View Articletitled, Hemolytic anemia and severe rhabdomyolysis caused by compound heterozygous mutations of the gene for erythrocyte/muscle isozyme of aldolase, ALDOA(Arg303X/Cys338Tyr)

Plasmodium falciparum induces reorganization of host membrane proteins during intraerythrocytic growth
Brief Report

Phillip D. Parker,Leann Tilley,Nectarios Klonis

View Articletitled, Plasmodium falciparum induces reorganization of host membrane proteins during intraerythrocytic growth

Screening hepcidin for mutations in juvenile hemochromatosis: identification of a new mutation (C70R)
Clinical Trials & Observations Brief Report

Antonella Roetto,Filomena Daraio,Paolo Porporato,Roberta Caruso,Timothy M. Cox,Mario Cazzola,Paolo Gasparini,Alberto Piperno,Clara Camaschella

View Articletitled, Screening hepcidin for mutations in juvenile hemochromatosis: identification of a new mutation (C70R)

TRANSPLANTATION

Chronic graft-versus-host disease is associated with increased numbers of peripheral blood CD4⁺CD25^high regulatory T cells

Fiona J. Clark,Richard Gregg,Karen Piper,Debbie Dunnion,Lisa Freeman,Mike Griffiths,Gulnaz Begum,Premini Mahendra,Charles Craddock,Paul Moss,Ronjon Chakraverty

View Articletitled, Chronic graft-versus-host disease is associated with increased numbers of peripheral blood CD4+CD25high regulatory T cells

A critical role for CCR2/MCP-1 interactions in the development of idiopathic pneumonia syndrome after allogeneic bone marrow transplantation

Gerhard C. Hildebrandt,Ulrich A. Duffner,Krystyna M. Olkiewicz,Leigh A. Corrion,Nicole E. Willmarth,Debra L. Williams,Shawn G. Clouthier,Cory M. Hogaboam,Pavan R. Reddy,Bethany B. Moore,William A. Kuziel,Chen Liu,Gregory Yanik,Kenneth R. Cooke

View Articletitled, A critical role for CCR2/MCP-1 interactions in the development of idiopathic pneumonia syndrome after allogeneic bone marrow transplantation

CORRESPONDENCE

Endogenous erythroid and megakaryocytic circulating progenitors, HUMARA clonality assay, and PRV-1 expression are useful tools for diagnosis of polycythemia vera and essential thrombocythemia

Lourdes Florensa,Carles Besses,Lurdes Zamora,Beatriz Bellosillo,Blanca Espinet,Sergi Serrano,Soledad Woessner,Francesc Solé

View Articletitled, Endogenous erythroid and megakaryocytic circulating progenitors, HUMARA clonality assay, and PRV-1 expression are useful tools for diagnosis of polycythemia vera and essential thrombocythemia

Usefulness of the quantitative assessment of PRV-1 gene expression for the diagnosis of polycythemia vera and essential thrombocythemia patients

Daniela Cilloni,Sonia Carturan,Enrico Gottardi,Francesca Messa,Milena Fava,Ilaria Defilippi,Francesca Arruga,Giuseppe Saglio

View Articletitled, Usefulness of the quantitative assessment of PRV-1 gene expression for the diagnosis of polycythemia vera and essential thrombocythemia patients

Not-so-novel phenotypes in the Fanconi anemia group D2 mouse model

Madeleine Carreau

View Articletitled, Not-so-novel phenotypes in the Fanconi anemia group D2 mouse model

Hepatitis B reactivation during combination chemotherapy for AIDS-related lymphoma is uncommon and does not adversely affect outcome

Justin Stebbing,Mark Atkins,Mark Nelson,Shefali Rajpopat,Tom Newsom-Davis,Brian Gazzard,Mark Bower

View Articletitled, Hepatitis B reactivation during combination chemotherapy for AIDS-related lymphoma is uncommon and does not adversely affect outcome

Issue Archive

Table of Contents

INSIDE BLOOD

PLENARY PAPERS

PERSPECTIVES

The impact of cytomegalovirus serostatus of donor and recipient before hematopoietic stem cell transplantation in the era of antiviral prophylaxis and preemptive therapy Clinical Trials & Observations

CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS

Janus kinase 3 (JAK3) deficiency: clinical, immunologic, and molecular analyses of 10 patients and outcomes of stem cell transplantation Clinical Trials & Observations

Acquired somatic ATRX mutations in myelodysplastic syndrome associated with α thalassemia (ATMDS) convey a more severe hematologic phenotype than germline ATRX mutations Clinical Trials & Observations

Early prediction of outcome and response to alemtuzumab therapy in chronic lymphocytic leukemia Clinical Trials & Observations

Biologic response to desmopressin in patients with severe type 1 and type 2 von Willebrand disease: results of a multicenter European study Clinical Trials & Observations

Sustained long-term hematologic efficacy of hydroxyurea at maximum tolerated dose in children with sickle cell disease Clinical Trials & Observations

GENE THERAPY

HEMATOPOIESIS

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

Hyperprothrombinemia associated with prothrombin G20210A mutation inhibits plasma fibrinolysis through a TAFI-mediated mechanism Clinical Trials & Observations

IMMUNOBIOLOGY

NEOPLASIA

Molecular response to imatinib in late chronic-phase chronic myeloid leukemia Clinical Trials & Observations

Monoclonal CD5+ and CD5- B-lymphocyte expansions are frequent in the peripheral blood of the elderly Clinical Trials & Observations

Mutations of the PML tumor suppressor gene in acute promyelocytic leukemia Brief Report

PHAGOCYTES

RED CELLS

Gene interactions and stroke risk in children with sickle cell anemia Clinical Trials & Observations

Intravenous immune globulin prevents venular vaso-occlusion in sickle cell mice by inhibiting leukocyte adhesion and the interactions between sickle erythrocytes and adherent leukocytes Brief Report

Hemolytic anemia and severe rhabdomyolysis caused by compound heterozygous mutations of the gene for erythrocyte/muscle isozyme of aldolase, ALDOA(Arg303X/Cys338Tyr) Brief Report

Plasmodium falciparum induces reorganization of host membrane proteins during intraerythrocytic growth Brief Report

Screening hepcidin for mutations in juvenile hemochromatosis: identification of a new mutation (C70R) Clinical Trials & Observations Brief Report

TRANSPLANTATION

CORRESPONDENCE

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American Society of Hematology

This Feature Is Available To Subscribers Only

The impact of cytomegalovirus serostatus of donor and recipient before hematopoietic stem cell transplantation in the era of antiviral prophylaxis and preemptive therapy
Clinical Trials & Observations

Janus kinase 3 (JAK3) deficiency: clinical, immunologic, and molecular analyses of 10 patients and outcomes of stem cell transplantation
Clinical Trials & Observations

Acquired somatic ATRX mutations in myelodysplastic syndrome associated with α thalassemia (ATMDS) convey a more severe hematologic phenotype than germline ATRX mutations
Clinical Trials & Observations

Early prediction of outcome and response to alemtuzumab therapy in chronic lymphocytic leukemia
Clinical Trials & Observations

Biologic response to desmopressin in patients with severe type 1 and type 2 von Willebrand disease: results of a multicenter European study
Clinical Trials & Observations

Sustained long-term hematologic efficacy of hydroxyurea at maximum tolerated dose in children with sickle cell disease
Clinical Trials & Observations

Hyperprothrombinemia associated with prothrombin G20210A mutation inhibits plasma fibrinolysis through a TAFI-mediated mechanism
Clinical Trials & Observations

Molecular response to imatinib in late chronic-phase chronic myeloid leukemia
Clinical Trials & Observations

Monoclonal CD5⁺ and CD5^- B-lymphocyte expansions are frequent in the peripheral blood of the elderly
Clinical Trials & Observations

Mutations of the PML tumor suppressor gene in acute promyelocytic leukemia
Brief Report

Gene interactions and stroke risk in children with sickle cell anemia
Clinical Trials & Observations

Intravenous immune globulin prevents venular vaso-occlusion in sickle cell mice by inhibiting leukocyte adhesion and the interactions between sickle erythrocytes and adherent leukocytes
Brief Report

Hemolytic anemia and severe rhabdomyolysis caused by compound heterozygous mutations of the gene for erythrocyte/muscle isozyme of aldolase, ALDOA^{(Arg303X/Cys338Tyr)}
Brief Report

Plasmodium falciparum induces reorganization of host membrane proteins during intraerythrocytic growth
Brief Report

Screening hepcidin for mutations in juvenile hemochromatosis: identification of a new mutation (C70R)
Clinical Trials & Observations Brief Report