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INSIDE BLOOD

In pursuit of a complete remission: exploring novel therapeutic agents in CLL

Michael R. Grever

View Articletitled, In pursuit of a complete remission: exploring novel therapeutic agents in CLL

Forging iron links

Nancy C. Andrews,Cindy N. Roy

View Articletitled, Forging iron links

New insights into chronic idiopathic neutropenia

David C. Dale

View Articletitled, New insights into chronic idiopathic neutropenia

Von Willebrand factor: a matrix protein that tries to be soluble

Zaverio M. Ruggeri

View Articletitled, Von Willebrand factor: a matrix protein that tries to be soluble

Bypassing the requirement for MYC in lymphoma progression

Kevin Shannon

View Articletitled, Bypassing the requirement for MYC in lymphoma progression

Fishing for evolutionary clues to globin gene regulation

Ross C. Hardison

View Articletitled, Fishing for evolutionary clues to globin gene regulation

BLOOD WORK

Acute megakaryoblastic leukemia

View Articletitled, Acute megakaryoblastic leukemia

EDITORIALS

A (blood) smear campaign

Sanford J. Shattil, MD

View Articletitled, A (blood) smear campaign

PLENARY PAPERS

The vitamin D3 analog EB1089 induces apoptosis via a p53-independent mechanism involving p38 MAP kinase activation and suppression of ERK activity in B-cell chronic lymphocytic leukemia cells in vitro

Chris Pepper,Alun Thomas,Terry Hoy,Donald Milligan,Paul Bentley,Chris Fegan

View Articletitled, The vitamin D3 analog EB1089 induces apoptosis via a p53-independent mechanism involving p38 MAP kinase activation and suppression of ERK activity in B-cell chronic lymphocytic leukemia cells in vitro

Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein
Brief Report

Elizabeta Nemeth,Erika V. Valore,Mary Territo,Gary Schiller,Alan Lichtenstein,Tomas Ganz

View Articletitled, Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein

ERRATA

Erratum for vol. 100, p. 1566

View Articletitled, Erratum for vol. 100, p. 1566

REVIEW ARTICLES

Splenic marginal zone lymphoma
Clinical Trials & Observations

Vito Franco,Ada Maria Florena,Emilio Iannitto

View Articletitled, Splenic marginal zone lymphoma

CHEMOKINES

Coincident expression of the chemokine receptors CCR6 and CCR7 by pathologic Langerhans cells in Langerhans cell histiocytosis
Brief Report

Mark D. Fleming,Jack L. Pinkus,Sarah W. Alexander,Carmen Tam,Massimo Loda,Stephen E. Sallan,Kim E. Nichols,David F. Carpentieri,Geraldine S. Pinkus,Barrett J. Rollins

View Articletitled, Coincident expression of the chemokine receptors CCR6 and CCR7 by pathologic Langerhans cells in Langerhans cell histiocytosis

CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS

A comparison of allogeneic and autologous bone marrow transplantation for lymphoblastic lymphoma
Clinical Trials & Observations

John E. Levine,Richard E. Harris,Fausto R. Loberiza, Jr,James O. Armitage,Julie M. Vose,Koen Van Besien,Hillard M. Lazarus,Mary M. Horowitz,on behalf of the Lymphoma Study Writing Committee of the International Bone Marrow Transplant Registry and Autologous Blood and Marrow Transplant Registry

View Articletitled, A comparison of allogeneic and autologous bone marrow transplantation for lymphoblastic lymphoma

Genetic and nutritional factors contributing to hyperhomocysteinemia in young adults
Clinical Trials & Observations

Leo A. J. Kluijtmans,Ian S. Young,Colin A. Boreham,Liam Murray,Dorothy McMaster,Helene McNulty,J. J. Strain,Joseph McPartlin,John M. Scott,Alexander S. Whitehead

View Articletitled, Genetic and nutritional factors contributing to hyperhomocysteinemia in young adults

Nongastric marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue
Clinical Trials & Observations

View Articletitled, Nongastric marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue

POEMS syndrome: definitions and long-term outcome: Presented in abstract form at the 41st annual meeting of the American Society of Hematology, New Orleans, LA, December 3-7, 1999.
Clinical Trials & Observations

Angela Dispenzieri,Robert A. Kyle,Martha Q. Lacy,S. Vincent Rajkumar,Terry M. Therneau,Dirk R. Larson,Philip R. Greipp,Thomas E. Witzig,Rita Basu,Guillermo A. Suarez,Rafael Fonseca,John A. Lust,Morie A. Gertz

View Articletitled, POEMS syndrome: definitions and long-term outcome: Presented in abstract form at the 41st annual meeting of the American Society of Hematology, New Orleans, LA, December 3-7, 1999.

Circulating CD20 is detectable in the plasma of patients with chronic lymphocytic leukemia and is of prognostic significance
Clinical Trials & Observations

Taghi Manshouri,Kim-anh Do,Xuemei Wang,Francis J. Giles,Susan M. O'Brien,Helen Saffer,Deborah Thomas,Iman Jilani,Hagop M. Kantarjian,Michael J. Keating,Maher Albitar

View Articletitled, Circulating CD20 is detectable in the plasma of patients with chronic lymphocytic leukemia and is of prognostic significance

B7-H1 is up-regulated in HIV infection and is a novel surrogate marker of disease progression
Clinical Trials & Observations

Daria Trabattoni,Marina Saresella,Mara Biasin,Adriano Boasso,Luca Piacentini,Pasquale Ferrante,Haidong Dong,Renato Maserati,Gene M. Shearer,Lieping Chen,Mario Clerici

View Articletitled, B7-H1 is up-regulated in HIV infection and is a novel surrogate marker of disease progression

Quantitative real-time RT-PCR analysis of PML-RARα mRNA in acute promyelocytic leukemia: assessment of prognostic significance in adult patients from intergroup protocol 0129
Clinical Trials & Observations

Robert E. Gallagher,Beow Y. Yeap,Wanli Bi,Kenneth J. Livak,Nike Beaubier,Sreenivas Rao,Clara D. Bloomfield,Frederick R. Appelbaum,Martin S. Tallman,James L. Slack,Cheryl L. Willman

View Articletitled, Quantitative real-time RT-PCR analysis of PML-RARα mRNA in acute promyelocytic leukemia: assessment of prognostic significance in adult patients from intergroup protocol 0129

Thromboembolic events in children with acute lymphoblastic leukemia (BFM protocols): prednisone versus dexamethasone administration
Clinical Trials & Observations

Ulrike Nowak-Göttl,Elvira Ahlke,Gudrun Fleischhack,Dirk Schwabe,Rosmarie Schobess,Christiane Schumann,Ralf Junker

View Articletitled, Thromboembolic events in children with acute lymphoblastic leukemia (BFM protocols): prednisone versus dexamethasone administration

A phase 2 trial of combination low-dose thalidomide and prednisone for the treatment of myelofibrosis with myeloid metaplasia
Clinical Trials & Observations

Ruben A. Mesa,David P. Steensma,Animesh Pardanani,Chin-Yang Li,Michelle Elliott,Scott H. Kaufmann,Gregory Wiseman,Leigh A. Gray,Georgene Schroeder,Terra Reeder,Jerome B. Zeldis,Ayalew Tefferi

View Articletitled, A phase 2 trial of combination low-dose thalidomide and prednisone for the treatment of myelofibrosis with myeloid metaplasia

Pathogenic molds (including Aspergillus species) in hospital water distribution systems: a 3-year prospective study and clinical implications for patients with hematologic malignancies
Clinical Trials & Observations

Elias J. Anaissie,Shawna L. Stratton,M. Cecilia Dignani,Choon-kee Lee,Richard C. Summerbell,John H. Rex,Thomas P. Monson,Thomas J. Walsh

View Articletitled, Pathogenic molds (including Aspergillus species) in hospital water distribution systems: a 3-year prospective study and clinical implications for patients with hematologic malignancies

High incidence of t(11;18)(q21;q21) in Helicobacter pylori–negative gastric MALT lymphoma
Clinical Trials & Observations Brief Report

Hongtao Ye,Hongxiang Liu,Markus Raderer,Andreas Chott,Agnes Ruskone-Fourmestraux,Andrew Wotherspoon,Martin J. S. Dyer,Shih-Sung Chuang,Ahmet Dogan,Peter G. Isaacson,Ming-Qing Du

View Articletitled, High incidence of t(11;18)(q21;q21) in Helicobacter pylori–negative gastric MALT lymphoma

GENE THERAPY

Humoral immune response in mice against a circulating antigen induced by adenoviral transfer is strictly dependent on expression in antigen-presenting cells

Bart R. De Geest,Sophie A. Van Linthout,Désiré Collen

View Articletitled, Humoral immune response in mice against a circulating antigen induced by adenoviral transfer is strictly dependent on expression in antigen-presenting cells

Oncolytic measles viruses displaying a single-chain antibody against CD38, a myeloma cell marker

Kah-Whye Peng,Kathleen A. Donovan,Urs Schneider,Roberto Cattaneo,John A. Lust,Stephen J. Russell

View Articletitled, Oncolytic measles viruses displaying a single-chain antibody against CD38, a myeloma cell marker

Persistence and expression of the adenosine deaminase gene for 12 years and immune reaction to gene transfer components: long-term results of the first clinical gene therapy trial

Linda Mesler Muul,Laura M. Tuschong,Sherry Lau Soenen,G. Jayashree Jagadeesh,W. Jay Ramsey,Zhifeng Long,Charles S. Carter,Elizabeth K. Garabedian,Melinna Alleyne,Margaret Brown,Wendy Bernstein,Shepherd H. Schurman,Thomas A. Fleisher,Susan F. Leitman,Cynthia E. Dunbar,R. Michael Blaese,Fabio Candotti

View Articletitled, Persistence and expression of the adenosine deaminase gene for 12 years and immune reaction to gene transfer components: long-term results of the first clinical gene therapy trial

HEMATOPOIESIS

Role of the WT1 tumor suppressor in murine hematopoiesis

Julia A. Alberta,Gregory M. Springett,Helen Rayburn,Thomas A. Natoli,Janet Loring,Jordan A. Kreidberg,David Housman

View Articletitled, Role of the WT1 tumor suppressor in murine hematopoiesis

Bcl-X_L is required for heme synthesis during the chemical induction of erythroid differentiation of murine erythroleukemia cells independently of its antiapoptotic function

Khalid Hafid-Medheb,Yvette Augery-Bourget,Marie-Nathalie Minatchy,Nicole Hanania,Jacqueline Robert-Lézénès

View Articletitled, Bcl-XL is required for heme synthesis during the chemical induction of erythroid differentiation of murine erythroleukemia cells independently of its antiapoptotic function

Signaling mechanisms coupled to tyrosines in the granulocyte colony-stimulating factor receptor orchestrate G-CSF–induced expansion of myeloid progenitor cells

Mirjam H. A. Hermans,Gert-Jan van de Geijn,Claudia Antonissen,Judith Gits,Daphne van Leeuwen,Alister C. Ward,Ivo P. Touw

View Articletitled, Signaling mechanisms coupled to tyrosines in the granulocyte colony-stimulating factor receptor orchestrate G-CSF–induced expansion of myeloid progenitor cells

Impaired granulocytopoiesis in patients with chronic idiopathic neutropenia is associated with increased apoptosis of bone marrow myeloid progenitor cells

Helen A. Papadaki,Aristides G. Eliopoulos,Theodoros Kosteas,Claudia Gemetzi,Athina Damianaki,Helen Koutala,Juergen Bux,George D. Eliopoulos

View Articletitled, Impaired granulocytopoiesis in patients with chronic idiopathic neutropenia is associated with increased apoptosis of bone marrow myeloid progenitor cells

SgIGSF: a new mast-cell adhesion molecule used for attachment to fibroblasts and transcriptionally regulated by MITF

Akihiko Ito,Tomoko Jippo,Tomohiko Wakayama,Eiichi Morii,Yu-ichiro Koma,Hiroaki Onda,Hiroshi Nojima,Shoichi Iseki,Yukihiko Kitamura

View Articletitled, SgIGSF: a new mast-cell adhesion molecule used for attachment to fibroblasts and transcriptionally regulated by MITF

Short-term injection of antiapoptotic cytokine combinations soon after lethal γ-irradiation promotes survival

Francis Hérodin,Philippe Bourin,Jean-François Mayol,Jean-Jacques Lataillade,Michel Drouet

View Articletitled, Short-term injection of antiapoptotic cytokine combinations soon after lethal γ-irradiation promotes survival

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

Antihirudin antibodies following low-dose subcutaneous treatment with desirudin for thrombosis prophylaxis after hip-replacement surgery: incidence and clinical relevance
Clinical Trials & Observations

Andreas Greinacher,Petra Eichler,Dorothea Albrecht,Ulrike Strobel,Bernd Pötzsch,Bengt I. Eriksson

View Articletitled, Antihirudin antibodies following low-dose subcutaneous treatment with desirudin for thrombosis prophylaxis after hip-replacement surgery: incidence and clinical relevance

Interleukin-17 promotes angiogenesis and tumor growth

Muneo Numasaki,Jun-ichi Fukushi,Mayumi Ono,Satwant K. Narula,Paul J. Zavodny,Toshio Kudo,Paul D. Robbins,Hideaki Tahara,Michael T. Lotze

View Articletitled, Interleukin-17 promotes angiogenesis and tumor growth

Lactadherin inhibits enzyme complexes of blood coagulation by competing for phospholipid-binding sites

Jialan Shi,Gary E. Gilbert

View Articletitled, Lactadherin inhibits enzyme complexes of blood coagulation by competing for phospholipid-binding sites

Aspects of hydrodynamic shear regulating shear-induced platelet activation and self-association of von Willebrand factor in suspension

Harish Shankaran,Paschalis Alexandridis,Sriram Neelamegham

View Articletitled, Aspects of hydrodynamic shear regulating shear-induced platelet activation and self-association of von Willebrand factor in suspension

Supplemental data

The roles of α_IIbβ₃-mediated outside-in signal transduction, thromboxane A2, and adenosine diphosphate in collagen-induced platelet aggregation

Moon J. Cho,Junling Liu,Tamara I. Pestina,Shirley A. Steward,Dennis W. Thomas,Thomas M. Coffman,Demin Wang,Carl W. Jackson,T. Kent Gartner

View Articletitled, The roles of αIIbβ3-mediated outside-in signal transduction, thromboxane A2, and adenosine diphosphate in collagen-induced platelet aggregation

Inflammation-promoting activity of HMGB1 on human microvascular endothelial cells

Carmen Fiuza,Michael Bustin,Shefali Talwar,Margaret Tropea,Eric Gerstenberger,James H. Shelhamer,Anthony F. Suffredini

View Articletitled, Inflammation-promoting activity of HMGB1 on human microvascular endothelial cells

Platelet P-selectin facilitates atherosclerotic lesion development

Peter C. Burger,Denisa D. Wagner

View Articletitled, Platelet P-selectin facilitates atherosclerotic lesion development

Shear stress inhibits adhesion molecule expression in vascular endothelial cells induced by coculture with smooth muscle cells

Jeng-Jiann Chiu,Li-Jing Chen,Pei-Ling Lee,Chih-I Lee,Leu-Wei Lo,Shunichi Usami,Shu Chien

View Articletitled, Shear stress inhibits adhesion molecule expression in vascular endothelial cells induced by coculture with smooth muscle cells

Effective contribution of transplanted vascular progenitor cells derived from embryonic stem cells to adult neovascularization in proper differentiation stage
Brief Report

Takami Yurugi-Kobayashi,Hiroshi Itoh,Jun Yamashita,Kenichi Yamahara,Hideyo Hirai,Takuya Kobayashi,Minetaro Ogawa,Satomi Nishikawa,Shin-Ichi Nishikawa,Kazuwa Nakao

View Articletitled, Effective contribution of transplanted vascular progenitor cells derived from embryonic stem cells to adult neovascularization in proper differentiation stage

IMMUNOBIOLOGY

A1 is a growth-permissive antiapoptotic factor mediating postactivation survival in T cells

Juana Gonzalez,Amos Orlofsky,Michael B. Prystowsky

View Articletitled, A1 is a growth-permissive antiapoptotic factor mediating postactivation survival in T cells

Primary immune responses to human CMV: a critical role for IFN-γ–producing CD4⁺ T cells in protection against CMV disease

Laila E. Gamadia,Ester B. M. Remmerswaal,Jan F. Weel,Frederieke Bemelman,René A. W. van Lier,Ineke J. M. Ten Berge

View Articletitled, Primary immune responses to human CMV: a critical role for IFN-γ–producing CD4+ T cells in protection against CMV disease

Analysis of TCR, pTα, and RAG-1 in T-acute lymphoblastic leukemias improves understanding of early human T-lymphoid lineage commitment
Clinical Trials & Observations

Vahid Asnafi,Kheira Beldjord,Emmanuelle Boulanger,Béatrice Comba,Patricia Le Tutour,Marie-Hélène Estienne,Frédéric Davi,Judith Landman-Parker,Pierre Quartier,Agnès Buzyn,Eric Delabesse,Françoise Valensi,Elizabeth Macintyre

View Articletitled, Analysis of TCR, pTα, and RAG-1 in T-acute lymphoblastic leukemias improves understanding of early human T-lymphoid lineage commitment

Antigen presentation by mouse CD4⁺ T cells involving acquired MHC class II:peptide complexes: another mechanism to limit clonal expansion?

Julia Y. S. Tsang,Jian Guo Chai,Robert Lechler

View Articletitled, Antigen presentation by mouse CD4+ T cells involving acquired MHC class II:peptide complexes: another mechanism to limit clonal expansion?

Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8⁺ T cells

Jason M. Brenchley,Nitin J. Karandikar,Michael R. Betts,David R. Ambrozak,Brenna J. Hill,Laura E. Crotty,Joseph P. Casazza,Janaki Kuruppu,Stephen A. Migueles,Mark Connors,Mario Roederer,Daniel C. Douek,Richard A. Koup

View Articletitled, Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8+ T cells

Effects of B7-blocking agent and/or CsA on induction of platelet-specific T-cell anergy in chronic autoimmune thrombocytopenic purpura
Clinical Trials & Observations

Jun Peng,Chuanfang Liu,Dai Liu,Cuiai Ren,Wei Li,Zhenguang Wang,Nianzeng Xing,Conggao Xu,Xueliang Chen,Chunyan Ji,Maohong Zhang,Ming Hou

View Articletitled, Effects of B7-blocking agent and/or CsA on induction of platelet-specific T-cell anergy in chronic autoimmune thrombocytopenic purpura

Type I interferon differential therapy for erythroleukemia: specificity of STAT activation

Vanessa S. Cull,Peta A. Tilbrook,Emmalene J. Bartlett,Natalie L. Brekalo,Cassandra M. James

View Articletitled, Type I interferon differential therapy for erythroleukemia: specificity of STAT activation

Biochemical and functional characterization of Rab27a mutations occurring in Griscelli syndrome patients
Clinical Trials & Observations

Gaël Ménasché,Jérôme Feldmann,Anne Houdusse,Catherine Desaymard,Alain Fischer,Bruno Goud,Geneviève de Saint Basile

View Articletitled, Biochemical and functional characterization of Rab27a mutations occurring in Griscelli syndrome patients

NEOPLASIA

Sensitivity to l-asparaginase is not associated with expression levels of asparagine synthetase in t(12;21)⁺pediatric ALL
Clinical Trials & Observations

Wendy A. G. Stams,Monique L. den Boer,H. Berna Beverloo,Jules P. P. Meijerink,Rolinda L. Stigter,Elisabeth R. van Wering,Gritta E. Janka-Schaub,Rosalyn Slater,Rob Pieters

View Articletitled, Sensitivity to l-asparaginase is not associated with expression levels of asparagine synthetase in t(12;21)+pediatric ALL

Expression of ribosomal and translation-associated genes is correlated with a favorable clinical course in chronic lymphocytic leukemia

Jan Dürig,Holger Nückel,Andreas Hüttmann,Elisabeth Kruse,Tanja Hölter,Katja Halfmeyer,Anja Führer,Roland Rudolph,Naser Kalhori,Arnd Nusch,Silvia Deaglio,Fabio Malavasi,Tarik Möröy,Ludger Klein-Hitpass,Ulrich Dührsen

View Articletitled, Expression of ribosomal and translation-associated genes is correlated with a favorable clinical course in chronic lymphocytic leukemia

Interleukin 4–induced gene 1 is activated in primary mediastinal large B-cell lymphoma
Clinical Trials & Observations

Christiane Copie-Bergman,Marie-Laure Boulland,Catherine Dehoulle,Peter Möller,Jean-Pierre Farcet,Martin J. S. Dyer,Corinne Haioun,Paul-Henri Roméo,Philippe Gaulard,Karen Leroy

View Articletitled, Interleukin 4–induced gene 1 is activated in primary mediastinal large B-cell lymphoma

CD40 induces human multiple myeloma cell migration via phosphatidylinositol 3–kinase/AKT/NF-κB signaling

Yu-Tzu Tai,Klaus Podar,Nicholas Mitsiades,Boris Lin,Constantine Mitsiades,Deepak Gupta,Masaharu Akiyama,Laurence Catley,Teru Hideshima,Nikhil C. Munshi,Steven P. Treon,Kenneth C. Anderson

View Articletitled, CD40 induces human multiple myeloma cell migration via phosphatidylinositol 3–kinase/AKT/NF-κB signaling

CYP1A12B (Val)* allele is overrepresented in a subgroup of acute myeloid leukemia patients with poor-risk karyotype associated with NRAS mutation, but not associated withFLT3 internal tandem duplication

David T. Bowen,Marion E. Frew,Sara Rollinson,Philippa L. Roddam,Ann Dring,Martyn T. Smith,Stephen E. Langabeer,Gareth J. Morgan

View Articletitled, CYP1A1*2B (Val) allele is overrepresented in a subgroup of acute myeloid leukemia patients with poor-risk karyotype associated with NRAS mutation, but not associated withFLT3 internal tandem duplication

Paracrine interactions of basic fibroblast growth factor and interleukin-6 in multiple myeloma

Guido Bisping,Regine Leo,Doris Wenning,Berno Dankbar,Teresa Padró,Martin Kropff,Christian Scheffold,Matthias Kröger,Rolf M. Mesters,Wolfgang E. Berdel,Joachim Kienast

View Articletitled, Paracrine interactions of basic fibroblast growth factor and interleukin-6 in multiple myeloma

SOCS-1, a negative regulator of cytokine signaling, is frequently silenced by methylation in multiple myeloma

Oliver Galm,Hirohide Yoshikawa,Manel Esteller,Rainhardt Osieka,James G. Herman

View Articletitled, SOCS-1, a negative regulator of cytokine signaling, is frequently silenced by methylation in multiple myeloma

High-level expression of BCL3 differentiates t(2;5)(p23;q35)-positive anaplastic large cell lymphoma from Hodgkin disease

Momoko Nishikori,Yoshitomo Maesako,Chiyoko Ueda,Masayuki Kurata,Takashi Uchiyama,Hitoshi Ohno

View Articletitled, High-level expression of BCL3 differentiates t(2;5)(p23;q35)-positive anaplastic large cell lymphoma from Hodgkin disease

Genomically complex lymphomas undergo sustained tumor regression upon MYC inactivation unless they acquire novel chromosomal translocations

Åsa Karlsson,Sylvie Giuriato,Flora Tang,Jingly Fung-Weier,Göran Levan,Dean W. Felsher

View Articletitled, Genomically complex lymphomas undergo sustained tumor regression upon MYC inactivation unless they acquire novel chromosomal translocations

PHAGOCYTES

Felic (CIP4b), a novel binding partner with the Src kinase Lyn and Cdc42, localizes to the phagocytic cup

Patrice Dombrosky-Ferlan,Anatoly Grishin,Roberto J. Botelho,Matthew Sampson,Lin Wang,William A. Rudert,Sergio Grinstein,Seth J. Corey

View Articletitled, Felic (CIP4b), a novel binding partner with the Src kinase Lyn and Cdc42, localizes to the phagocytic cup

The heat shock protein Gp96 binds to human neutrophils and monocytes and stimulates effector functions

Markus P. Radsak,Norbert Hilf,Harpreet Singh-Jasuja,Sibylla Braedel,Peter Brossart,Hans-Georg Rammensee,Hansjoerg Schild

View Articletitled, The heat shock protein Gp96 binds to human neutrophils and monocytes and stimulates effector functions

PECAM-1–dependent neutrophil transmigration is independent of monolayer PECAM-1 signaling or localization

Christopher D. O'Brien,Poay Lim,Jing Sun,Steven M. Albelda

View Articletitled, PECAM-1–dependent neutrophil transmigration is independent of monolayer PECAM-1 signaling or localization

RED CELLS

HbF reactivation in sibling BFU-E colonies: synergistic interaction of kit ligand with low-dose dexamethasone

Marco Gabbianelli,Ugo Testa,Adriana Massa,Ornella Morsilli,Ernestina Saulle,Nadia Maria Sposi,Eleonora Petrucci,Gualtiero Mariani,Cesare Peschle

View Articletitled, HbF reactivation in sibling BFU-E colonies: synergistic interaction of kit ligand with low-dose dexamethasone

The spectrum of PIG-A gene mutations in aplastic anemia/paroxysmal nocturnal hemoglobinuria (AA/PNH): a high incidence of multiple mutations and evidence of a mutational hot spot
Clinical Trials & Observations

Yousef Mortazavi,Bruno Merk,Jenny McIntosh,Judith C. W. Marsh,Hubert Schrezenmeier,Tim R. Rutherford,for the BIOMED II Pathophysiology and Treatment of Aplastic Anaemia Study Group

View Articletitled, The spectrum of PIG-A gene mutations in aplastic anemia/paroxysmal nocturnal hemoglobinuria (AA/PNH): a high incidence of multiple mutations and evidence of a mutational hot spot

Functional and comparative analysis of globin loci in pufferfish and humans

Nynke Gillemans,Tara McMorrow,Rita Tewari,Albert W. K. Wai,Carola Burgtorf,Dubravka Drabek,Nicki Ventress,An Langeveld,Douglas Higgs,Kian Tan-Un,Frank Grosveld,Sjaak Philipsen

View Articletitled, Functional and comparative analysis of globin loci in pufferfish and humans

Src-family kinase signaling modulates the adhesion ofPlasmodium falciparum on human microvascular endothelium under flow

Bryan G. Yipp,Stephen M. Robbins,Mary E. Resek,Dror I. Baruch,Sornchai Looareesuwan,May Ho

View Articletitled, Src-family kinase signaling modulates the adhesion ofPlasmodium falciparum on human microvascular endothelium under flow

A single viral protein HCMV US2 affects antigen presentation and intracellular iron homeostasis by degradation of classical HLA class I and HFE molecules

Sayeh Vahdati-Ben Arieh,Nihay Laham,Chana Schechter,Jon W. Yewdell,John E. Coligan,Rachel Ehrlich

View Articletitled, A single viral protein HCMV US2 affects antigen presentation and intracellular iron homeostasis by degradation of classical HLA class I and HFE molecules

Distinct HLA associations by stroke subtype in children with sickle cell anemia

Carolyn Hoppe,William Klitz,Janelle Noble,Lara Vigil,Elliott Vichinsky,Lori Styles

View Articletitled, Distinct HLA associations by stroke subtype in children with sickle cell anemia

TRANSFUSION MEDICINE

A novel I-branching β-1,6-N-acetylglucosaminyltransferase involved in human blood group I antigen expression

Niro Inaba,Toru Hiruma,Akira Togayachi,Hiroko Iwasaki,Xiao-Hui Wang,Yusuke Furukawa,Ryoichi Sumi,Takashi Kudo,Katsuya Fujimura,Toshie Iwai,Masanori Gotoh,Mitsuru Nakamura,Hisashi Narimatsu

View Articletitled, A novel I-branching β-1,6-N-acetylglucosaminyltransferase involved in human blood group I antigen expression

TRANSPLANTATION

Pretreatment of donors with interleukin-18 attenuates acute graft-versus-host disease via STAT6 and preserves graft-versus-leukemia effects

Pavan Reddy,Takanori Teshima,Gerhard Hildebrandt,Debra L. Williams,Chen Liu,Kenneth R. Cooke,James L.M. Ferrara

View Articletitled, Pretreatment of donors with interleukin-18 attenuates acute graft-versus-host disease via STAT6 and preserves graft-versus-leukemia effects

The influence of immunosuppressive drugs on tolerance induction through bone marrow transplantation with costimulation blockade

Peter Blaha,Sinda Bigenzahn,Zvonimir Koporc,Maximilian Schmid,Felix Langer,Edgar Selzer,Helga Bergmeister,Friedrich Wrba,Josef Kurtz,Christopher Kiss,Erich Roth,Ferdinand Muehlbacher,Megan Sykes,Thomas Wekerle

View Articletitled, The influence of immunosuppressive drugs on tolerance induction through bone marrow transplantation with costimulation blockade

CORRESPONDENCE

Estimation of cell membrane alteration after drug treatment by LDH release

Vladimir Jurisic

View Articletitled, Estimation of cell membrane alteration after drug treatment by LDH release

Diagnostic criteria for acute erythroleukemia

Dale M. Selby,Riccardo Valdez,Bertram Schnitzer,Charles W. Ross,William G. Finn

View Articletitled, Diagnostic criteria for acute erythroleukemia

CYP2C9 exon 4 mutations and warfarin dose phenotype in Asians

Allan E. Rettie,Guoying Tai,David L. Veenstra,Fred M. Farin,Sengkeo Srinouanprachan,Yvonne S. Lin,Kenneth E. Thummel,Ronald N. Hines

View Articletitled, CYP2C9 exon 4 mutations and warfarin dose phenotype in Asians

The role of erythrocyte peroxiredoxin in detoxifying peroxides and in stimulating potassium efflux via the Gardos channels

Ewald Schröder,Thomas Jönsson,Leslie Poole

View Articletitled, The role of erythrocyte peroxiredoxin in detoxifying peroxides and in stimulating potassium efflux via the Gardos channels

Low levels of serum elastase are not associated with mutations in ELA-2 elastase encoding gene in chronic idiopathic neutropenia

Helen A. Papadaki,Marshall Horwitz,Stavroula A. Coulocheri,Richard A. Person,Kathleen F. Benson,George D. Eliopoulos

View Articletitled, Low levels of serum elastase are not associated with mutations in ELA-2 elastase encoding gene in chronic idiopathic neutropenia

Issue Archive

Table of Contents

INSIDE BLOOD

BLOOD WORK

EDITORIALS

PLENARY PAPERS

Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein Brief Report

ERRATA

REVIEW ARTICLES

Splenic marginal zone lymphoma Clinical Trials & Observations

CHEMOKINES

Coincident expression of the chemokine receptors CCR6 and CCR7 by pathologic Langerhans cells in Langerhans cell histiocytosis Brief Report

CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS

A comparison of allogeneic and autologous bone marrow transplantation for lymphoblastic lymphoma Clinical Trials & Observations

Genetic and nutritional factors contributing to hyperhomocysteinemia in young adults Clinical Trials & Observations

Nongastric marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue Clinical Trials & Observations

POEMS syndrome: definitions and long-term outcome: Presented in abstract form at the 41st annual meeting of the American Society of Hematology, New Orleans, LA, December 3-7, 1999. Clinical Trials & Observations

Circulating CD20 is detectable in the plasma of patients with chronic lymphocytic leukemia and is of prognostic significance Clinical Trials & Observations

B7-H1 is up-regulated in HIV infection and is a novel surrogate marker of disease progression Clinical Trials & Observations

Quantitative real-time RT-PCR analysis of PML-RARα mRNA in acute promyelocytic leukemia: assessment of prognostic significance in adult patients from intergroup protocol 0129 Clinical Trials & Observations

Thromboembolic events in children with acute lymphoblastic leukemia (BFM protocols): prednisone versus dexamethasone administration Clinical Trials & Observations

A phase 2 trial of combination low-dose thalidomide and prednisone for the treatment of myelofibrosis with myeloid metaplasia Clinical Trials & Observations

Pathogenic molds (including Aspergillus species) in hospital water distribution systems: a 3-year prospective study and clinical implications for patients with hematologic malignancies Clinical Trials & Observations

High incidence of t(11;18)(q21;q21) in Helicobacter pylori–negative gastric MALT lymphoma Clinical Trials & Observations Brief Report