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INSIDE BLOOD

Bringing blood to life

Mervin C. Yoder, Jr

View Articletitled, Bringing blood to life

Extending the scope of FTIs

Selina M. Luger

View Articletitled, Extending the scope of FTIs

Closing the gap for detection of residual posttransplantation leukemia?

Dietrich W. Beelen

View Articletitled, Closing the gap for detection of residual posttransplantation leukemia?

Expanding uses of high-dose factor VIIa

Maureane Hoffman

View Articletitled, Expanding uses of high-dose factor VIIa

Is the cure worse than the disease?

Gordon L. Phillips, II

View Articletitled, Is the cure worse than the disease?

BLOOD WORK

Peripheral smear in pernicious anemia

View Articletitled, Peripheral smear in pernicious anemia

PLENARY PAPERS

Circulation is established in a stepwise pattern in the mammalian embryo

Kathleen E. McGrath,Anne D. Koniski,Jeffrey Malik,James Palis

View Articletitled, Circulation is established in a stepwise pattern in the mammalian embryo

ERRATA

Erratum for vol. 100, p. 3419

View Articletitled, Erratum for vol. 100, p. 3419

Erratum for vol. 101, p. 1200

View Articletitled, Erratum for vol. 101, p. 1200

CHEMOKINES

CCR4 versus CCR10 in human cutaneous T_H lymphocyte trafficking

Dulce Soler,Tricia L. Humphreys,Stanley M. Spinola,James J. Campbell

View Articletitled, CCR4 versus CCR10 in human cutaneous TH lymphocyte trafficking

Simian immunodeficiency virus dramatically alters expression of homeostatic chemokines and dendritic cell markers during infection in vivo

Yang Kyu Choi,Beth A. Fallert,Michael A. Murphey-Corb,Todd A. Reinhart

View Articletitled, Simian immunodeficiency virus dramatically alters expression of homeostatic chemokines and dendritic cell markers during infection in vivo

CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS

Efficacy of the farnesyl transferase inhibitor R115777 in chronic myeloid leukemia and other hematologic malignancies
Clinical Trials & Observations

Jorge Cortes,Maher Albitar,Deborah Thomas,Francis Giles,Razelle Kurzrock,Alain Thibault,Wayne Rackoff,Charles Koller,Susan O'Brien,Guillermo Garcia-Manero,Moshe Talpaz,Hagop Kantarjian

View Articletitled, Efficacy of the farnesyl transferase inhibitor R115777 in chronic myeloid leukemia and other hematologic malignancies

The usefulness of monitoring WT1 gene transcripts for the prediction and management of relapse following allogeneic stem cell transplantation in acute type leukemia
Clinical Trials & Observations

Hiroyasu Ogawa,Hiroya Tamaki,Kazuhiro Ikegame,Toshihiro Soma,Manabu Kawakami,Akihiro Tsuboi,Eui Ho Kim,Naoki Hosen,Masaki Murakami,Tatsuya Fujioka,Tomoki Masuda,Yuki Taniguchi,Sumiyuki Nishida,Yusuke Oji,Yoshihiro Oka,Haruo Sugiyama

View Articletitled, The usefulness of monitoring WT1 gene transcripts for the prediction and management of relapse following allogeneic stem cell transplantation in acute type leukemia

Insights into leukocyte adhesion deficiency type 2 from a novel mutation in the GDP-fucose transporter gene
Clinical Trials & Observations

Andrés Hidalgo,Songhui Ma,Anna J. Peired,Linnea A. Weiss,Charlotte Cunningham-Rundles,Paul S. Frenette

View Articletitled, Insights into leukocyte adhesion deficiency type 2 from a novel mutation in the GDP-fucose transporter gene

Successful treatment of juvenile myelomonocytic leukemia relapsing after stem cell transplantation using donor lymphocyte infusion
Clinical Trials & Observations Brief Report

Austen Worth,Kanchana Rao,David Webb,Judith Chessells,Jane Passmore,Paul Veys

View Articletitled, Successful treatment of juvenile myelomonocytic leukemia relapsing after stem cell transplantation using donor lymphocyte infusion

Prognostic value of angiogenesis in solitary bone plasmacytoma
Clinical Trials & Observations Brief Report

Shaji Kumar,Rafael Fonseca,Angela Dispenzieri,Martha Q. Lacy,John A. Lust,Linda Wellik,Thomas E. Witzig,Morie A. Gertz,Robert A. Kyle,Philip R. Greipp,S. Vincent Rajkumar

View Articletitled, Prognostic value of angiogenesis in solitary bone plasmacytoma

GENE THERAPY

Local and systemic effects of an allogeneic tumor cell vaccine combining transgenic human lymphotactin with interleukin-2 in patients with advanced or refractory neuroblastoma
Clinical Trials & Observations

Raphaël F. Rousseau,Ann E. Haight,Charlotte Hirschmann-Jax,Eric S. Yvon,Donna R. Rill,Zhuyong Mei,Susan C. Smith,Shannon Inman,Kristine Cooper,Pat Alcoser,Bambi Grilley,Adrian Gee,Edwina Popek,Andrew Davidoff,Laura C. Bowman,Malcolm K. Brenner,Douglas Strother

View Articletitled, Local and systemic effects of an allogeneic tumor cell vaccine combining transgenic human lymphotactin with interleukin-2 in patients with advanced or refractory neuroblastoma

Efficient transduction of primary human B lymphocytes and nondividing myeloma B cells with HIV-1–derived lentiviral vectors

Fabrice Bovia,Patrick Salmon,Thomas Matthes,Krisztian Kvell,Tuan H. Nguyen,Christiane Werner-Favre,Marc Barnet,Monika Nagy,Florence Leuba,Jean-François Arrighi,Vincent Piguet,Didier Trono,Rudolf H. Zubler

View Articletitled, Efficient transduction of primary human B lymphocytes and nondividing myeloma B cells with HIV-1–derived lentiviral vectors

Therapeutic factor VIII levels and negligible toxicity in mouse and dog models of hemophilia A following gene therapy with high-capacity adenoviral vectors

Marinee K. L. Chuah,Gudrun Schiedner,Lieven Thorrez,Brian Brown,Marion Johnston,Veerle Gillijns,Sabine Hertel,Nico Van Rooijen,David Lillicrap,Désiré Collen,Thierry VandenDriessche,Stefan Kochanek

View Articletitled, Therapeutic factor VIII levels and negligible toxicity in mouse and dog models of hemophilia A following gene therapy with high-capacity adenoviral vectors

HEMATOPOIESIS

Stromal inhibition of megakaryocytic differentiation is associated with blockade of sustained Rap1 activation

Lorrie L. Delehanty,Michael Mogass,Sara L. Gonias,Frederick K. Racke,Brian Johnstone,Adam N. Goldfarb

View Articletitled, Stromal inhibition of megakaryocytic differentiation is associated with blockade of sustained Rap1 activation

Neutrophil elastase enzymatically antagonizes the in vitro action of G-CSF: implications for the regulation of granulopoiesis

Frank El Ouriaghli,Hiroshi Fujiwara,J. Joseph Melenhorst,Giuseppe Sconocchia,Nancy Hensel,A. John Barrett

View Articletitled, Neutrophil elastase enzymatically antagonizes the in vitro action of G-CSF: implications for the regulation of granulopoiesis

High-level ectopic HOXB4 expression confers a profound in vivo competitive growth advantage on human cord blood CD34⁺ cells, but impairs lymphomyeloid differentiation

Bernhard Schiedlmeier,Hannes Klump,Elke Will,Gökhan Arman-Kalcek,Zhixiong Li,Zheng Wang,Andreas Rimek,Jutta Friel,Christopher Baum,Wolfram Ostertag

View Articletitled, High-level ectopic HOXB4 expression confers a profound in vivo competitive growth advantage on human cord blood CD34+ cells, but impairs lymphomyeloid differentiation

Enforced expression of CUL-4A interferes with granulocytic differentiation and exit from the cell cycle

Binghui Li,Feng-Chun Yang,D. Wade Clapp,Kristin T. Chun

View Articletitled, Enforced expression of CUL-4A interferes with granulocytic differentiation and exit from the cell cycle

HES-1 preserves purified hematopoietic stem cells ex vivo and accumulates side population cells in vivo

Atsushi Kunisato,Shigeru Chiba,Etsuko Nakagami-Yamaguchi,Keiki Kumano,Toshiki Saito,Shigeo Masuda,Tomoyuki Yamaguchi,Masatake Osawa,Ryoichiro Kageyama,Hiromitsu Nakauchi,Mitsuo Nishikawa,Hisamaru Hirai

View Articletitled, HES-1 preserves purified hematopoietic stem cells ex vivo and accumulates side population cells in vivo

Combined effects of Notch signaling and cytokines induce a multiple log increase in precursors with lymphoid and myeloid reconstituting ability

Barbara Varnum-Finney,Carolyn Brashem-Stein,Irwin D. Bernstein

View Articletitled, Combined effects of Notch signaling and cytokines induce a multiple log increase in precursors with lymphoid and myeloid reconstituting ability

Novel secreted isoform of adhesion molecule ICAM-4: potential regulator of membrane-associated ICAM-4 interactions

Gloria Lee,Frances A. Spring,Stephen F. Parsons,Tosti J. Mankelow,Luanne L. Peters,Mark J. Koury,Narla Mohandas,David J. Anstee,Joel Anne Chasis

View Articletitled, Novel secreted isoform of adhesion molecule ICAM-4: potential regulator of membrane-associated ICAM-4 interactions

BVL-1–like VL30 promoter sustains long-term expression in erythroid progenitor cells
Brief Report

William R. Staplin,Joseph A. Knezetic

View Articletitled, BVL-1–like VL30 promoter sustains long-term expression in erythroid progenitor cells

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

Neuropilin-1 on hematopoietic cells as a source of vascular development

Yoshihiro Yamada,Yuichi Oike,Hisao Ogawa,Yasuhiro Ito,Hajime Fujisawa,Toshio Suda,Nobuyuki Takakura

View Articletitled, Neuropilin-1 on hematopoietic cells as a source of vascular development

Membrane-type matrix metalloproteinase-mediated angiogenesis in a fibrin-collagen matrix

Annemie Collen,Roeland Hanemaaijer,Florea Lupu,Paul H. A. Quax,Natascha van Lent,Jos Grimbergen,Erna Peters,Pieter Koolwijk,Victor W. M. van Hinsbergh

View Articletitled, Membrane-type matrix metalloproteinase-mediated angiogenesis in a fibrin-collagen matrix

The angiogenic regulator CD13/APN is a transcriptional target of Ras signaling pathways in endothelial morphogenesis

Shripad V. Bhagwat,Nenad Petrovic,Yasuhiro Okamoto,Linda H. Shapiro

View Articletitled, The angiogenic regulator CD13/APN is a transcriptional target of Ras signaling pathways in endothelial morphogenesis

Lupus anticoagulants are stronger risk factors for thrombosis than anticardiolipin antibodies in the antiphospholipid syndrome: a systematic review of the literature
Clinical Trials & Observations

Monica Galli,Davide Luciani,Guido Bertolini,Tiziano Barbui

View Articletitled, Lupus anticoagulants are stronger risk factors for thrombosis than anticardiolipin antibodies in the antiphospholipid syndrome: a systematic review of the literature

An intronic polymorphism in the PAR-1 gene is associated with platelet receptor density and the response to SFLLRN

Annabelle Dupont,Pierre Fontana,Christilla Bachelot-Loza,Jean-Luc Reny,Ivan Bièche,Florence Desvard,Martine Aiach,Pascale Gaussem

View Articletitled, An intronic polymorphism in the PAR-1 gene is associated with platelet receptor density and the response to SFLLRN

The 4G5G polymorphism in the gene for PAI-1 and the circadian oscillation of plasma PAI-1
Clinical Trials & Observations

Johanna G. van der Bom,Michiel L. Bots,Frits Haverkate,Cornelis Kluft,Diederick E. Grobbee

View Articletitled, The 4G5G polymorphism in the gene for PAI-1 and the circadian oscillation of plasma PAI-1

von Willebrand factor cleaving protease and ADAMTS13mutations in childhood TTP
Clinical Trials & Observations

Reinhard Schneppenheim,Ulrich Budde,Florian Oyen,Dorothea Angerhaus,Volker Aumann,Elke Drewke,Wolf Hassenpflug,Johannes Häberle,Karim Kentouche,Elisabeth Kohne,Karin Kurnik,Dirk Mueller-Wiefel,Tobias Obser,René Santer,Karl-Walter Sykora

View Articletitled, von Willebrand factor cleaving protease and ADAMTS13mutations in childhood TTP

Outcome of donor splice site mutations accounting for congenital afibrinogenemia reflects order of intron removal in the fibrinogen alpha gene (FGA)

Catia Attanasio,Armelle David,Marguerite Neerman-Arbez

View Articletitled, Outcome of donor splice site mutations accounting for congenital afibrinogenemia reflects order of intron removal in the fibrinogen alpha gene (FGA)

Angiostatin selectively inhibits signaling by hepatocyte growth factor in endothelial and smooth muscle cells

Nadeem Wajih,David C. Sane

View Articletitled, Angiostatin selectively inhibits signaling by hepatocyte growth factor in endothelial and smooth muscle cells

Recombinant factor VIIa enhances deposition of platelets with congenital or acquired α_IIbβ₃ deficiency to endothelial cell matrix and collagen under conditions of flow via tissue factor–independent thrombin generation

Ton Lisman,Sultana Moschatsis,Jelle Adelmeijer,H. Karel Nieuwenhuis,Philip G. De Groot

View Articletitled, Recombinant factor VIIa enhances deposition of platelets with congenital or acquired αIIbβ3 deficiency to endothelial cell matrix and collagen under conditions of flow via tissue factor–independent thrombin generation

Myocardial fibrosis in mice with overexpression of human blood coagulation factor IX
Brief Report

Afshin Ameri,Sumiko Kurachi,Katsuo Sueishi,Mitsuhiro Kuwahara,Kotoku Kurachi

View Articletitled, Myocardial fibrosis in mice with overexpression of human blood coagulation factor IX

IMMUNOBIOLOGY

Constitutive exclusion of Csk from Hck-positive membrane microdomains permits Src kinase-dependent proliferation ofTheileria-transformed B lymphocytes

Martin Baumgartner,Pavla Angelisová,Niclas Setterblad,Nuala Mooney,Dirk Werling,Václav Horejsı́,Gordon Langsley

View Articletitled, Constitutive exclusion of Csk from Hck-positive membrane microdomains permits Src kinase-dependent proliferation ofTheileria-transformed B lymphocytes

Extracellular ubiquitin inhibits the TNF-α response to endotoxin in peripheral blood mononuclear cells and regulates endotoxin hyporesponsiveness in critical illness
Clinical Trials & Observations

Matthias Majetschak,Ulrich Krehmeier,Mark Bardenheuer,Christof Denz,Michael Quintel,Gregor Voggenreiter,Udo Obertacke

View Articletitled, Extracellular ubiquitin inhibits the TNF-α response to endotoxin in peripheral blood mononuclear cells and regulates endotoxin hyporesponsiveness in critical illness

Evidence for naive T-cell repopulation despite thymus irradiation after autologous transplantation in adults with multiple myeloma: role of ex vivo CD34⁺ selection and age

Marion Malphettes,Guislaine Carcelain,Pierre Saint-Mezard,Véronique Leblond,Hester Korthals Altes,Jean-Pierre Marolleau,Patrice Debré,Jean-Claude Brouet,Jean-Paul Fermand,Brigitte Autran

View Articletitled, Evidence for naive T-cell repopulation despite thymus irradiation after autologous transplantation in adults with multiple myeloma: role of ex vivo CD34+ selection and age

Non-IgE–dependent activation of human lung– and cord blood–derived mast cells is induced by eosinophil major basic protein and modulated by the membrane form of stem cell factor

Adrian M. Piliponsky,Gerald J. Gleich,Arnon Nagler,Ilan Bar,Francesca Levi-Schaffer

View Articletitled, Non-IgE–dependent activation of human lung– and cord blood–derived mast cells is induced by eosinophil major basic protein and modulated by the membrane form of stem cell factor

Generating CTLs against the subdominant Epstein-Barr virus LMP1 antigen for the adoptive immunotherapy of EBV-associated malignancies

Stephen Gottschalk,Oliver L. Edwards,Uluhan Sili,M. Helen Huls,Tatiana Goltsova,Alan R. Davis,Helen E. Heslop,Cliona M. Rooney

View Articletitled, Generating CTLs against the subdominant Epstein-Barr virus LMP1 antigen for the adoptive immunotherapy of EBV-associated malignancies

The HTLV receptor is an early T-cell activation marker whose expression requires de novo protein synthesis

Nicolas Manel,Sandrina Kinet,Jean-Luc Battini,Felix J. Kim,Naomi Taylor,Marc Sitbon

View Articletitled, The HTLV receptor is an early T-cell activation marker whose expression requires de novo protein synthesis

NEOPLASIA

NPM-ALK transgenic mice spontaneously develop T-cell lymphomas and plasma cell tumors

Roberto Chiarle,Jerald Z. Gong,Ilaria Guasparri,Anna Pesci,Jonjing Cai,Jian Liu,William J. Simmons,Girish Dhall,Jennifer Howes,Roberto Piva,Giorgio Inghirami

View Articletitled, NPM-ALK transgenic mice spontaneously develop T-cell lymphomas and plasma cell tumors

Nuclear localization of cyclin B1 regulates DNA damage–induced apoptosis

Lisa A. Porter,I. Howard Cukier,Jonathan M. Lee

View Articletitled, Nuclear localization of cyclin B1 regulates DNA damage–induced apoptosis

Evi3, a common retroviral integration site in murine B-cell lymphoma, encodes an EBFAZ-related Krüppel-like zinc finger protein

Søren Warming,Pentao Liu,Takeshi Suzuki,Keiko Akagi,Susan Lindtner,George N. Pavlakis,Nancy A. Jenkins,Neal G. Copeland

View Articletitled, Evi3, a common retroviral integration site in murine B-cell lymphoma, encodes an EBFAZ-related Krüppel-like zinc finger protein

Emergence of clonal cytogenetic abnormalities in Ph⁻cells in some CML patients in cytogenetic remission to imatinib but restoration of polyclonal hematopoiesis in the majority

Thomas Bumm,Christel Müller,Haifa-Kathrin Al-Ali,Knut Krohn,Patricia Shepherd,Erika Schmidt,Sabine Leiblein,Christina Franke,Evelin Hennig,Thomas Friedrich,Reiner Krahl,Dietger Niederwieser,Michael W. N. Deininger

View Articletitled, Emergence of clonal cytogenetic abnormalities in Ph−cells in some CML patients in cytogenetic remission to imatinib but restoration of polyclonal hematopoiesis in the majority

Oscillation between B-lymphoid and myeloid lineages in Myc-induced hematopoietic tumors following spontaneous silencing/reactivation of the EBF/Pax5 pathway

Duonan Yu,David Allman,Michael H. Goldschmidt,Michael L. Atchison,John G. Monroe,Andrei Thomas-Tikhonenko

View Articletitled, Oscillation between B-lymphoid and myeloid lineages in Myc-induced hematopoietic tumors following spontaneous silencing/reactivation of the EBF/Pax5 pathway

The human herpes virus 8–encoded viral FLICE inhibitory protein protects against growth factor withdrawal–induced apoptosis via NF-κB activation

Qinmiao Sun,Hittu Matta,Preet M. Chaudhary

View Articletitled, The human herpes virus 8–encoded viral FLICE inhibitory protein protects against growth factor withdrawal–induced apoptosis via NF-κB activation

CD100/Plexin-B1 interactions sustain proliferation and survival of normal and leukemic CD5⁺ B lymphocytes

Luisa Granziero,Paola Circosta,Cristina Scielzo,Elisa Frisaldi,Stefania Stella,Massimo Geuna,Silvia Giordano,Paolo Ghia,Federico Caligaris-Cappio

View Articletitled, CD100/Plexin-B1 interactions sustain proliferation and survival of normal and leukemic CD5+ B lymphocytes

Platelet-endothelial interaction in tumor angiogenesis and microcirculation

Philipp C. Manegold,Joerg Hutter,Sascha A. Pahernik,Konrad Messmer,Marc Dellian

View Articletitled, Platelet-endothelial interaction in tumor angiogenesis and microcirculation

All-trans-retinoic acid induces CD52 expression in acute promyelocytic leukemia
Brief Report

Shi-Wu Li,Dongqi Tang,Kim P. Ahrens,Jin-Xiong She,Raul C. Braylan,Lijun Yang

View Articletitled, All-trans-retinoic acid induces CD52 expression in acute promyelocytic leukemia

Both B and T lymphocytes may be clonally involved in myelofibrosis with myeloid metaplasia
Clinical Trials & Observations Brief Report

Terra L. Reeder,Richard J. Bailey,Gordon W. Dewald,Ayalew Tefferi

View Articletitled, Both B and T lymphocytes may be clonally involved in myelofibrosis with myeloid metaplasia

Leukemic potential of doubly mutant Nf1 andW^v hematopoietic cells
Brief Report

David A. Ingram,Mary Jo Wenning,Kevin Shannon,D. Wade Clapp

View Articletitled, Leukemic potential of doubly mutant Nf1 andWv hematopoietic cells

PHAGOCYTES

Tumor necrosis factor α induces a caspase-independent death pathway in human neutrophils

Nikolai A. Maianski,Dirk Roos,Taco W. Kuijpers

View Articletitled, Tumor necrosis factor α induces a caspase-independent death pathway in human neutrophils

RED CELLS

Mitochondrial ferritin expression in erythroid cells from patients with sideroblastic anemia

Mario Cazzola,Rosangela Invernizzi,Gaetano Bergamaschi,Sonia Levi,Barbara Corsi,Erica Travaglino,Valeria Rolandi,Giorgio Biasiotto,Jim Drysdale,Paolo Arosio

View Articletitled, Mitochondrial ferritin expression in erythroid cells from patients with sideroblastic anemia

Induction of fetal hemoglobin expression by the histone deacetylase inhibitor apicidin

Olaf Witt,Sven Mönkemeyer,Gabi Rönndahl,Bernhard Erdlenbruch,Dirk Reinhardt,Katrin Kanbach,Arnulf Pekrun

View Articletitled, Induction of fetal hemoglobin expression by the histone deacetylase inhibitor apicidin

Heterotypic interactions between transferrin receptor and transferrin receptor 2

Todd M. Vogt,Aaron D. Blackwell,Anthony M. Giannetti,Pamela J. Bjorkman,Caroline A. Enns

View Articletitled, Heterotypic interactions between transferrin receptor and transferrin receptor 2

TRANSPLANTATION

Myelodysplastic syndrome and acute myeloid leukemia after autotransplantation for lymphoma: a multicenter case-control study
Clinical Trials & Observations

Catherine Metayer,Rochelle E. Curtis,Julie Vose,Kathleen A. Sobocinski,Mary M. Horowitz,Smita Bhatia,Joseph W. Fay,Cesar O. Freytes,Steven C. Goldstein,Roger H. Herzig,Armand Keating,Carol B. Miller,Thomas J. Nevill,Andrew L. Pecora,J. Douglas Rizzo,Stephanie F. Williams,Chin-Yang Li,Lois B. Travis,Daniel J. Weisdorf

View Articletitled, Myelodysplastic syndrome and acute myeloid leukemia after autotransplantation for lymphoma: a multicenter case-control study

Total lymphoid irradiation nonmyeloablative preconditioning enriches for IL-4–producing CD4⁺-TNK cells and skews differentiation of immunocompetent donor CD4⁺cells

Shawn M. Rigby,Todd Rouse,Elizabeth H. Field

View Articletitled, Total lymphoid irradiation nonmyeloablative preconditioning enriches for IL-4–producing CD4+-TNK cells and skews differentiation of immunocompetent donor CD4+cells

Donor pretreatment with progenipoietin-1 is superior to granulocyte colony–stimulating factor in preventing graft-versus-host disease after allogeneic stem cell transplantation

Kelli P. A. MacDonald,Vanessa Rowe,Cheryl Filippich,Ranjeny Thomas,Andrew D. Clouston,Joseph K. Welply,Derek N. J. Hart,James L. M. Ferrara,Geoffrey R. Hill

View Articletitled, Donor pretreatment with progenipoietin-1 is superior to granulocyte colony–stimulating factor in preventing graft-versus-host disease after allogeneic stem cell transplantation

Cyclophosphamide metabolism, liver toxicity, and mortality following hematopoietic stem cell transplantation
Clinical Trials & Observations

George B. McDonald,John T. Slattery,Michelle E. Bouvier,Song Ren,Ami L. Batchelder,Thomas F. Kalhorn,H. Gary Schoch,Claudio Anasetti,Ted Gooley

View Articletitled, Cyclophosphamide metabolism, liver toxicity, and mortality following hematopoietic stem cell transplantation

Unmutated immunoglobulin variable heavy-chain gene status remains an adverse prognostic factor after autologous stem cell transplantation for chronic lymphocytic leukemia

Matthias Ritgen,Alexandra Lange,Stephan Stilgenbauer,Hartmut Döhner,Christian Bretscher,Heidi Bosse,Ariane Stuhr,Michael Kneba,Peter Dreger

View Articletitled, Unmutated immunoglobulin variable heavy-chain gene status remains an adverse prognostic factor after autologous stem cell transplantation for chronic lymphocytic leukemia

Engraftment of human CD34⁺ cells leads to widespread distribution of donor-derived cells and correction of tissue pathology in a novel murine xenotransplantation model of lysosomal storage disease

A. Alex Hofling,Carole Vogler,Michael H. Creer,Mark S. Sands

View Articletitled, Engraftment of human CD34+ cells leads to widespread distribution of donor-derived cells and correction of tissue pathology in a novel murine xenotransplantation model of lysosomal storage disease

High-dose immune suppression and autologous hematopoietic stem cell transplantation in refractory Crohn disease
Clinical Trials & Observations Brief Report

Richard K. Burt,Ann Traynor,Yu Oyama,Robert Craig

View Articletitled, High-dose immune suppression and autologous hematopoietic stem cell transplantation in refractory Crohn disease

Donor CMV serostatus has no impact on CMV viremia or disease when prophylactic granulocyte transfusions are given following allogeneic peripheral blood stem cell transplantation
Clinical Trials & Observations Brief Report

Ravi Vij,John F. DiPersio,Partha Venkatraman,Kathryn Trinkaus,Lawrence T. Goodnough,Randy A. Brown,Hanna J. Khoury,Steven M. Devine,Aarti Oza,Shalini Shenoy,William Blum,Douglas Adkins

View Articletitled, Donor CMV serostatus has no impact on CMV viremia or disease when prophylactic granulocyte transfusions are given following allogeneic peripheral blood stem cell transplantation

CORRESPONDENCE

Apoptotic synergism between STI571 and the farnesyl transferase inhibitor SCH66336 on an imatinib-sensitive cell line

Andres L. Brodsky

View Articletitled, Apoptotic synergism between STI571 and the farnesyl transferase inhibitor SCH66336 on an imatinib-sensitive cell line

Acidic and neutral sialidase in the erythrocytes of patients with type 2 diabetes: an answer to comments by Richard et al

Bruno Venerando,Amelia Fiorilli,Gianluigi Croci,Cristina Tringali,Giancarlo Goi,Laura Mazzanti,Giovanna Curatola,Giovanni Segalini,Luca Massaccesi,Adriana Lombardo,Guido Tettamanti

View Articletitled, Acidic and neutral sialidase in the erythrocytes of patients with type 2 diabetes: an answer to comments by Richard et al

Increased CMV infection following nonmyeloablative allogeneic stem cell transplantation: a search for the guilty

Suparno Chakrabarti

View Articletitled, Increased CMV infection following nonmyeloablative allogeneic stem cell transplantation: a search for the guilty

Issue Archive

Table of Contents

INSIDE BLOOD

BLOOD WORK

PLENARY PAPERS

ERRATA

CHEMOKINES

CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS

Efficacy of the farnesyl transferase inhibitor R115777 in chronic myeloid leukemia and other hematologic malignancies Clinical Trials & Observations

The usefulness of monitoring WT1 gene transcripts for the prediction and management of relapse following allogeneic stem cell transplantation in acute type leukemia Clinical Trials & Observations

Insights into leukocyte adhesion deficiency type 2 from a novel mutation in the GDP-fucose transporter gene Clinical Trials & Observations

Successful treatment of juvenile myelomonocytic leukemia relapsing after stem cell transplantation using donor lymphocyte infusion Clinical Trials & Observations Brief Report

Prognostic value of angiogenesis in solitary bone plasmacytoma Clinical Trials & Observations Brief Report

GENE THERAPY

Local and systemic effects of an allogeneic tumor cell vaccine combining transgenic human lymphotactin with interleukin-2 in patients with advanced or refractory neuroblastoma Clinical Trials & Observations

HEMATOPOIESIS

BVL-1–like VL30 promoter sustains long-term expression in erythroid progenitor cells Brief Report

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

Lupus anticoagulants are stronger risk factors for thrombosis than anticardiolipin antibodies in the antiphospholipid syndrome: a systematic review of the literature Clinical Trials & Observations

The 4G5G polymorphism in the gene for PAI-1 and the circadian oscillation of plasma PAI-1 Clinical Trials & Observations

von Willebrand factor cleaving protease and ADAMTS13mutations in childhood TTP Clinical Trials & Observations

Myocardial fibrosis in mice with overexpression of human blood coagulation factor IX Brief Report

IMMUNOBIOLOGY

Extracellular ubiquitin inhibits the TNF-α response to endotoxin in peripheral blood mononuclear cells and regulates endotoxin hyporesponsiveness in critical illness Clinical Trials & Observations

NEOPLASIA

All-trans-retinoic acid induces CD52 expression in acute promyelocytic leukemia Brief Report

Both B and T lymphocytes may be clonally involved in myelofibrosis with myeloid metaplasia Clinical Trials & Observations Brief Report

Leukemic potential of doubly mutant Nf1 andWv hematopoietic cells Brief Report